GR20010100097A - Μεθοδος παρασκευης της σιταλοπραμης - Google Patents

Μεθοδος παρασκευης της σιταλοπραμης

Info

Publication number
GR20010100097A
GR20010100097A GR20010100097A GR2001100097A GR20010100097A GR 20010100097 A GR20010100097 A GR 20010100097A GR 20010100097 A GR20010100097 A GR 20010100097A GR 2001100097 A GR2001100097 A GR 2001100097A GR 20010100097 A GR20010100097 A GR 20010100097A
Authority
GR
Greece
Prior art keywords
citalopram
preparation
formula
alkylated
aldehyde
Prior art date
Application number
GR20010100097A
Other languages
Greek (el)
English (en)
Inventor
Hans Petersen
Harold Michael Rock
Original Assignee
H.Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR20010100097(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H.Lundbeck A/S filed Critical H.Lundbeck A/S
Publication of GR20010100097A publication Critical patent/GR20010100097A/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
GR20010100097A 2000-02-24 2001-02-22 Μεθοδος παρασκευης της σιταλοπραμης GR20010100097A (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000296 2000-02-24

Publications (1)

Publication Number Publication Date
GR20010100097A true GR20010100097A (el) 2001-10-31

Family

ID=8159208

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010100097A GR20010100097A (el) 2000-02-24 2001-02-22 Μεθοδος παρασκευης της σιταλοπραμης

Country Status (29)

Country Link
US (3) US20020004604A1 (https=)
EP (1) EP1259500A1 (https=)
JP (1) JP2003524009A (https=)
KR (1) KR20020080438A (https=)
CN (1) CN1161350C (https=)
AU (1) AU2001235357A1 (https=)
BE (1) BE1012921A6 (https=)
BG (1) BG107015A (https=)
BR (1) BR0108947A (https=)
CA (1) CA2400682A1 (https=)
EA (1) EA005593B1 (https=)
FR (1) FR2805813A1 (https=)
GR (1) GR20010100097A (https=)
HK (1) HK1054378B (https=)
HR (1) HRP20020743A2 (https=)
HU (1) HUP0300078A3 (https=)
IE (1) IES20010143A2 (https=)
IL (1) IL151339A0 (https=)
IS (1) IS6512A (https=)
IT (1) ITMI20010385A1 (https=)
MX (1) MXPA02008230A (https=)
NL (1) NL1017414C1 (https=)
NO (1) NO20024007L (https=)
PL (1) PL357178A1 (https=)
SK (1) SK13662002A3 (https=)
TR (1) TR200202048T2 (https=)
UA (1) UA71059C2 (https=)
WO (1) WO2001062754A1 (https=)
ZA (2) ZA200206255B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
HRP20020344B1 (hr) 1999-10-25 2010-10-31 H. Lundbeck A/S Način priprave citaloprama
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
HUP0203635A3 (en) 1999-12-28 2005-02-28 Lundbeck & Co As H Method for the preparation of citalopram
PT1246813E (pt) 1999-12-30 2004-02-27 Lundbeck & Co As H Metodo para a preparacao de citalopram
CN1195749C (zh) * 2000-01-14 2005-04-06 H.隆德贝克有限公司 制备5－氰基2－苯并[c]呋喃酮的方法
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
KR20020080481A (ko) 2000-03-13 2002-10-23 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조 방법
CN1427835A (zh) 2000-03-13 2003-07-02 H·隆德贝克有限公司 5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
TR200202155T2 (tr) 2000-03-14 2002-12-23 H. Lundbeck A/S Sitalopramin preparasyon metodu
DE10190485T1 (de) * 2000-03-16 2002-03-21 Lundbeck & Co As H Verfahren zur Herstellung von 5-Cyano-1-(4-fluorphenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
DK1281707T3 (da) * 2001-08-02 2005-05-02 Infosint Sa Fremgangsmåde til fremstilling af 5-substituerede isobenzenfuraner
WO2004016602A1 (en) * 2002-08-14 2004-02-26 Natco Pharma Limited Process for the preparation of high purity citalopram and its pharmaceutically acceptable salts
US8539533B2 (en) * 2003-03-07 2013-09-17 Siemens Enterprise Communications, Inc. System and method for digital personal video stream manager
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
JP2006176490A (ja) * 2004-11-29 2006-07-06 Sumitomo Chemical Co Ltd ５−フタランカルボニトリル及びシタロプラムの製造方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136193A (en) * 1976-01-14 1979-01-23 Kefalas A/S Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans
WO1998019511A2 (en) * 1997-11-10 1998-05-14 H. Lundbeck A/S Method for the preparation of citalopram
WO1999030548A2 (en) * 1999-04-14 1999-06-24 H. Lundbeck A/S Method for the preparation of citalopram
EP1095926A2 (en) * 1999-11-01 2001-05-02 SUMIKA FINE CHEMICALS Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EP1125907A2 (en) * 2000-02-17 2001-08-22 SUMIKA FINE CHEMICALS Co., Ltd. Intermediates for the production of citalopram

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136193A (en) * 1976-01-14 1979-01-23 Kefalas A/S Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans
WO1998019511A2 (en) * 1997-11-10 1998-05-14 H. Lundbeck A/S Method for the preparation of citalopram
WO1999030548A2 (en) * 1999-04-14 1999-06-24 H. Lundbeck A/S Method for the preparation of citalopram
EP1095926A2 (en) * 1999-11-01 2001-05-02 SUMIKA FINE CHEMICALS Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EP1125907A2 (en) * 2000-02-17 2001-08-22 SUMIKA FINE CHEMICALS Co., Ltd. Intermediates for the production of citalopram

Also Published As

Publication number Publication date
BR0108947A (pt) 2003-06-03
CN1161350C (zh) 2004-08-11
HUP0300078A2 (en) 2003-05-28
UA71059C2 (uk) 2004-11-15
HK1054378B (zh) 2005-04-29
ZA200206255B (en) 2003-10-20
CN1404475A (zh) 2003-03-19
JP2003524009A (ja) 2003-08-12
AU2001235357A1 (en) 2001-09-03
IL151339A0 (en) 2003-04-10
FR2805813A1 (fr) 2001-09-07
EA200200900A1 (ru) 2003-02-27
IES20010143A2 (en) 2001-07-25
US20030114692A1 (en) 2003-06-19
HUP0300078A3 (en) 2005-02-28
US20030083508A1 (en) 2003-05-01
TR200202048T2 (tr) 2003-01-21
BE1012921A6 (fr) 2001-05-08
CA2400682A1 (en) 2001-08-30
SK13662002A3 (sk) 2003-01-09
PL357178A1 (en) 2004-07-26
KR20020080438A (ko) 2002-10-23
US20020004604A1 (en) 2002-01-10
IS6512A (is) 2002-08-20
EA005593B1 (ru) 2005-04-28
HK1054378A1 (en) 2003-11-28
NO20024007D0 (no) 2002-08-22
BG107015A (bg) 2003-05-30
NL1017414C1 (nl) 2001-03-15
ITMI20010385A1 (it) 2002-08-26
ZA200206699B (en) 2003-11-21
WO2001062754A1 (en) 2001-08-30
EP1259500A1 (en) 2002-11-27
MXPA02008230A (es) 2003-05-23
HRP20020743A2 (en) 2003-12-31
NO20024007L (no) 2002-10-07

Similar Documents

Publication Publication Date Title
GR20010100097A (el) Μεθοδος παρασκευης της σιταλοπραμης
GR1004074B (el) Μεθοδος παρασκευης της σιταλοπραμης.
ES2159488A1 (es) Procedimiento para la preparacion de derivados de pirimidona con actividad antifugica.
HUP0300856A2 (hu) Eljárás szubsztituált fenil-acetonitrilek elżállítására
IL159814A0 (en) Process for the production of beraprost an its salts
BG107050A (en) Method for the preparation of citalopram
EA200200101A1 (ru) Получение замещенных пиперидин-4-онов
DK1204658T3 (da) Benzofurylpiperazin-serotoninagonister
WO2002016322A3 (en) Process for the preparation of 2-aminoethylpyridines
BR0109176A (pt) Método para preparação de citalopram e composto da fórmula
IL155181A0 (en) A process for the preparation of pantoprazole and intermediates therefor
IS6527A (is) Aðferð til framleiðslu á sítalóprami
BG107048A (en) Method for the preparation of citalopram
WO2003029254A1 (en) Process for preparation of tricyclic compounds
DK1206452T3 (da) Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser
IL145449A0 (en) Processes for preparing pesticidal intermediates
TR200400293T4 (tr) 9-dihidro-13-asetilbasatin III'e ait suda çözünebilir 9-dihidro-paklitaksel türevlerinin sentezi.
AU2001250356A1 (en) Method for the production of spirocyclic tetronic acid derivatives
ATE254099T1 (de) Trimethyldecen-verbindungen
ITRM20010309A0 (it) Procedimento per la produzione di composti perfluoro-organici mediante florurazione elettrochimica.
IL154165A0 (en) Method for the production of imidazo-(1,2-c) (2,3)-benzodiazepines and intermediates in the production thereof
IN184757B (https=)
ES2194745T3 (es) Procedimiento para la obtencion de 4,6-dicloropirimidi-na.
GR20010100123A (el) Μεθοδος παρασκευης της σιταλοπραμης
CY1110529T1 (el) Παρασκευη ν-υποκατεστημενων 2,7-διαλκυλο-4-υδροξυ-5-αμινο-8-αρυλοοκτανοϋλαμιδιων