GB9215361D0 - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
GB9215361D0
GB9215361D0 GB929215361A GB9215361A GB9215361D0 GB 9215361 D0 GB9215361 D0 GB 9215361D0 GB 929215361 A GB929215361 A GB 929215361A GB 9215361 A GB9215361 A GB 9215361A GB 9215361 D0 GB9215361 D0 GB 9215361D0
Authority
GB
United Kingdom
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB929215361A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB929215361A priority Critical patent/GB9215361D0/en
Publication of GB9215361D0 publication Critical patent/GB9215361D0/en
Priority to CA002140662A priority patent/CA2140662A1/en
Priority to AU45795/93A priority patent/AU4579593A/en
Priority to EP93916105A priority patent/EP0651750A1/en
Priority to KR1019950700226A priority patent/KR950702563A/ko
Priority to CN93116598A priority patent/CN1088209A/zh
Priority to SI9300390A priority patent/SI9300390A/sl
Priority to HU9500171A priority patent/HUT76787A/hu
Priority to SK75-95A priority patent/SK7595A3/sk
Priority to ZA935213A priority patent/ZA935213B/xx
Priority to JP6504272A priority patent/JPH08502037A/ja
Priority to PL93307169A priority patent/PL307169A1/xx
Priority to MX9304355A priority patent/MX9304355A/es
Priority to RU95104939/04A priority patent/RU95104939A/ru
Priority to CZ95149A priority patent/CZ14995A3/cs
Priority to IL106385A priority patent/IL106385A0/xx
Priority to NZ254207A priority patent/NZ254207A/en
Priority to PCT/GB1993/001512 priority patent/WO1994002483A1/en
Priority to HR931066A priority patent/HRP931066A2/hr
Priority to YU50293A priority patent/YU50293A/sh
Priority to BG99359A priority patent/BG99359A/bg
Priority to FI950229A priority patent/FI950229A/fi
Priority to NO950202A priority patent/NO950202L/no
Priority to US08/743,283 priority patent/US5679694A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB929215361A 1992-07-20 1992-07-20 Heterocyclic compounds Pending GB9215361D0 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
GB929215361A GB9215361D0 (en) 1992-07-20 1992-07-20 Heterocyclic compounds
HR931066A HRP931066A2 (en) 1992-07-20 1993-07-19 Heterocyclic compounds
JP6504272A JPH08502037A (ja) 1992-07-20 1993-07-19 ４環性化合物、これらを調整するための方法及び中間体並びに抗腫瘍剤としてのこれらの使用
MX9304355A MX9304355A (es) 1992-07-20 1993-07-19 Compuestos heterociclicos.
EP93916105A EP0651750A1 (en) 1992-07-20 1993-07-19 Tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents
KR1019950700226A KR950702563A (ko) 1992-07-20 1993-07-19 테트라시클릭 화합물, 이것의 제조방법 및 중간체와, 항암제로서의 이들의 사용방법(tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents)
CN93116598A CN1088209A (zh) 1992-07-20 1993-07-19 杂环化合物
SI9300390A SI9300390A (en) 1992-07-20 1993-07-19 Pyrolo :3,2-b: carbazones, 1h benzofuro :3,2-f: indoles and 1h-:1: benzothieno :2,3-f: indoles and their use as anti-tumour agents
HU9500171A HUT76787A (en) 1992-07-20 1993-07-19 Pyrrole ring containing tetracyclic compounds, process for their preparation and pharmaceutical compositions containing them
SK75-95A SK7595A3 (en) 1992-07-20 1993-07-19 Tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents
ZA935213A ZA935213B (en) 1992-07-20 1993-07-19 Heterocyclic compounds
CA002140662A CA2140662A1 (en) 1992-07-20 1993-07-19 Tetracyclic compounds, process and intermediates for their preparation and their use as antitumour agents
PL93307169A PL307169A1 (en) 1992-07-20 1993-07-19 Tetracyclic compounds, method of and intermediate compounds for obtaining them and their application as anticarcinogenic agents
AU45795/93A AU4579593A (en) 1992-07-20 1993-07-19 Tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents
RU95104939/04A RU95104939A (ru) 1992-07-20 1993-07-19 Тетрациклические соединения, способ их получения и промежуточные соединения для этого и применение их в качестве противоопухолевых веществ
CZ95149A CZ14995A3 (en) 1992-07-20 1993-07-19 Tetracyclin compounds, process of their preparation, intermediates for their preparation and their use as antitumor preparations
IL106385A IL106385A0 (en) 1992-07-20 1993-07-19 Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
NZ254207A NZ254207A (en) 1992-07-20 1993-07-19 Tetracyclic derivatives antitumour medicaments and intermediate compounds (x and y are each s, c, o or n)
PCT/GB1993/001512 WO1994002483A1 (en) 1992-07-20 1993-07-19 Tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents
YU50293A YU50293A (sh) 1992-07-20 1993-07-20 Heterociklična jedinjenja
BG99359A BG99359A (bg) 1992-07-20 1995-01-18 Тетрациклинени съединения,метод и междинни съединения за тяхното получаване и прилагането им като антитуморни агенти
FI950229A FI950229A (fi) 1992-07-20 1995-01-19 Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineina
NO950202A NO950202L (no) 1992-07-20 1995-01-19 Tetracykliske forbindelser, fremgangsmåter og intermediater for fremstilling og anvendelse derav
US08/743,283 US5679694A (en) 1992-07-20 1996-11-04 Tetracyclic compounds, intermediates for their preparation and their use as antitumor agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929215361A GB9215361D0 (en) 1992-07-20 1992-07-20 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
GB9215361D0 true GB9215361D0 (en) 1992-09-02

Family

ID=10718981

Family Applications (1)

Application Number Title Priority Date Filing Date
GB929215361A Pending GB9215361D0 (en) 1992-07-20 1992-07-20 Heterocyclic compounds

Country Status (23)

Country Link
EP (1) EP0651750A1 (ru)
JP (1) JPH08502037A (ru)
KR (1) KR950702563A (ru)
CN (1) CN1088209A (ru)
AU (1) AU4579593A (ru)
BG (1) BG99359A (ru)
CA (1) CA2140662A1 (ru)
CZ (1) CZ14995A3 (ru)
FI (1) FI950229A (ru)
GB (1) GB9215361D0 (ru)
HR (1) HRP931066A2 (ru)
HU (1) HUT76787A (ru)
IL (1) IL106385A0 (ru)
MX (1) MX9304355A (ru)
NO (1) NO950202L (ru)
NZ (1) NZ254207A (ru)
PL (1) PL307169A1 (ru)
RU (1) RU95104939A (ru)
SI (1) SI9300390A (ru)
SK (1) SK7595A3 (ru)
WO (1) WO1994002483A1 (ru)
YU (1) YU50293A (ru)
ZA (1) ZA935213B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9401921D0 (en) * 1994-02-01 1994-03-30 Wellcome Found Heterocyclic compounds
GB9413758D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Heterocyclic compounds
GB9804343D0 (en) * 1998-02-27 1998-04-22 Univ Cardiff Chemical compounds
CA2437579C (en) * 2001-02-14 2012-05-01 Hector F. Deluca Preparations and use of an ah receptor ligand, 2-(1'h-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester
US7419992B2 (en) 2001-02-14 2008-09-02 Wisconsin Alumni Research Foundation Use of aryl hydrocarbon receptor ligand as a therapeutic intervention in angiogenesis-implicated disorders
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
WO2008051523A2 (en) * 2006-10-23 2008-05-02 Georgetown University Carbazole derivatives useful as medicaments in cancer therapy
WO2010019271A1 (en) 2008-08-15 2010-02-18 Georgetown University Fluorescent regulators of rassf1a expression and human cancer cell proliferation
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Ｅｇ５阻害剤
KR20160066490A (ko) * 2014-12-02 2016-06-10 주식회사 씨앤드씨신약연구소 헤테로사이클 유도체 및 그의 용도
US11053255B2 (en) 2015-06-22 2021-07-06 Georgetown University Synthesis of mahanine and related compounds
CN109776550B (zh) * 2019-01-17 2021-08-10 广东轻工职业技术学院 一种海洋真菌来源的生物碱化合物及其在制备食品防腐剂中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300688A1 (en) * 1987-07-21 1989-01-25 FISONS plc Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them
US5166204A (en) * 1989-11-01 1992-11-24 Toyama Chemical Co., Ltd. Isoindole derivatives and salts thereof and antitumor agent comprising the same
JPH06503549A (ja) * 1990-03-20 1994-04-21 ザ　ウェルカム　ファウンデーション　リミテッド 殺生物性ヘテロ多環状化合物およびそれらの医療における使用

Also Published As

Publication number Publication date
CZ14995A3 (en) 1995-10-18
FI950229A (fi) 1995-03-10
HUT76787A (en) 1997-11-28
FI950229A0 (fi) 1995-01-19
HU9500171D0 (en) 1995-03-28
CA2140662A1 (en) 1994-02-03
EP0651750A1 (en) 1995-05-10
NZ254207A (en) 1997-03-24
SI9300390A (en) 1994-03-31
JPH08502037A (ja) 1996-03-05
KR950702563A (ko) 1995-07-29
IL106385A0 (en) 1993-11-15
NO950202D0 (no) 1995-01-19
MX9304355A (es) 1994-04-29
PL307169A1 (en) 1995-05-15
YU50293A (sh) 1997-01-08
SK7595A3 (en) 1995-07-11
HRP931066A2 (en) 1995-12-31
CN1088209A (zh) 1994-06-22
RU95104939A (ru) 1996-10-27
NO950202L (no) 1995-01-19
ZA935213B (en) 1995-01-19
AU4579593A (en) 1994-02-14
BG99359A (bg) 1995-11-30
WO1994002483A1 (en) 1994-02-03

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Legal Events

Date Code Title Description
730A Proceeding under section 30 patents act 1977