FI950229A0 - Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineina - Google Patents
Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineinaInfo
- Publication number
- FI950229A0 FI950229A0 FI950229A FI950229A FI950229A0 FI 950229 A0 FI950229 A0 FI 950229A0 FI 950229 A FI950229 A FI 950229A FI 950229 A FI950229 A FI 950229A FI 950229 A0 FI950229 A0 FI 950229A0
- Authority
- FI
- Finland
- Prior art keywords
- intermediates
- processes
- preparation
- antitumor agents
- tetracyclic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929215361A GB9215361D0 (en) | 1992-07-20 | 1992-07-20 | Heterocyclic compounds |
| PCT/GB1993/001512 WO1994002483A1 (en) | 1992-07-20 | 1993-07-19 | Tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI950229A0 true FI950229A0 (fi) | 1995-01-19 |
| FI950229A FI950229A (fi) | 1995-03-10 |
Family
ID=10718981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI950229A FI950229A (fi) | 1992-07-20 | 1995-01-19 | Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineina |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0651750A1 (fi) |
| JP (1) | JPH08502037A (fi) |
| KR (1) | KR950702563A (fi) |
| CN (1) | CN1088209A (fi) |
| AU (1) | AU4579593A (fi) |
| BG (1) | BG99359A (fi) |
| CA (1) | CA2140662A1 (fi) |
| CZ (1) | CZ14995A3 (fi) |
| FI (1) | FI950229A (fi) |
| GB (1) | GB9215361D0 (fi) |
| HR (1) | HRP931066A2 (fi) |
| HU (1) | HUT76787A (fi) |
| IL (1) | IL106385A0 (fi) |
| MX (1) | MX9304355A (fi) |
| NO (1) | NO950202L (fi) |
| NZ (1) | NZ254207A (fi) |
| PL (1) | PL307169A1 (fi) |
| RU (1) | RU95104939A (fi) |
| SI (1) | SI9300390A (fi) |
| SK (1) | SK7595A3 (fi) |
| WO (1) | WO1994002483A1 (fi) |
| YU (1) | YU50293A (fi) |
| ZA (1) | ZA935213B (fi) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9401921D0 (en) * | 1994-02-01 | 1994-03-30 | Wellcome Found | Heterocyclic compounds |
| GB9413758D0 (en) * | 1994-07-07 | 1994-08-24 | Wellcome Found | Heterocyclic compounds |
| GB9804343D0 (en) * | 1998-02-27 | 1998-04-22 | Univ Cardiff | Chemical compounds |
| NZ527430A (en) * | 2001-02-14 | 2005-03-24 | Wisconsin Alumni Res Found | Preparations and use of an Ah receptor ligand, 2-(1'H-Indole-3'-Carbonyl)-thiazole-4-carboxylic acid methyl ester |
| US7419992B2 (en) | 2001-02-14 | 2008-09-02 | Wisconsin Alumni Research Foundation | Use of aryl hydrocarbon receptor ligand as a therapeutic intervention in angiogenesis-implicated disorders |
| GB0302094D0 (en) | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| GB0324269D0 (en) | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| WO2008051523A2 (en) * | 2006-10-23 | 2008-05-02 | Georgetown University | Carbazole derivatives useful as medicaments in cancer therapy |
| EP2323982B1 (en) | 2008-08-15 | 2012-02-29 | Georgetown University | Fluorescent regulators of rassf1a expression and human cancer cell proliferation |
| JP2012051804A (ja) * | 2008-12-26 | 2012-03-15 | Kyoto Univ | Ｅｇ５阻害剤 |
| KR20160066490A (ko) | 2014-12-02 | 2016-06-10 | 주식회사 씨앤드씨신약연구소 | 헤테로사이클 유도체 및 그의 용도 |
| US11053255B2 (en) | 2015-06-22 | 2021-07-06 | Georgetown University | Synthesis of mahanine and related compounds |
| CN109776550B (zh) * | 2019-01-17 | 2021-08-10 | 广东轻工职业技术学院 | 一种海洋真菌来源的生物碱化合物及其在制备食品防腐剂中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0300688A1 (en) * | 1987-07-21 | 1989-01-25 | FISONS plc | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them |
| US5166204A (en) * | 1989-11-01 | 1992-11-24 | Toyama Chemical Co., Ltd. | Isoindole derivatives and salts thereof and antitumor agent comprising the same |
| WO1991014688A1 (en) * | 1990-03-20 | 1991-10-03 | The Wellcome Foundation Limited | Hetero polycyclic biocidal compounds and their use in medecine |
-
1992
- 1992-07-20 GB GB929215361A patent/GB9215361D0/en active Pending
-
1993
- 1993-07-19 AU AU45795/93A patent/AU4579593A/en not_active Abandoned
- 1993-07-19 IL IL106385A patent/IL106385A0/xx unknown
- 1993-07-19 ZA ZA935213A patent/ZA935213B/xx unknown
- 1993-07-19 PL PL93307169A patent/PL307169A1/xx unknown
- 1993-07-19 KR KR1019950700226A patent/KR950702563A/ko not_active Application Discontinuation
- 1993-07-19 SK SK75-95A patent/SK7595A3/sk unknown
- 1993-07-19 CA CA002140662A patent/CA2140662A1/en not_active Abandoned
- 1993-07-19 RU RU95104939/04A patent/RU95104939A/ru unknown
- 1993-07-19 HU HU9500171A patent/HUT76787A/hu unknown
- 1993-07-19 MX MX9304355A patent/MX9304355A/es not_active IP Right Cessation
- 1993-07-19 NZ NZ254207A patent/NZ254207A/en unknown
- 1993-07-19 CN CN93116598A patent/CN1088209A/zh active Pending
- 1993-07-19 JP JP6504272A patent/JPH08502037A/ja active Pending
- 1993-07-19 EP EP93916105A patent/EP0651750A1/en not_active Withdrawn
- 1993-07-19 CZ CZ95149A patent/CZ14995A3/cs unknown
- 1993-07-19 SI SI9300390A patent/SI9300390A/sl unknown
- 1993-07-19 HR HR931066A patent/HRP931066A2/hr not_active Application Discontinuation
- 1993-07-19 WO PCT/GB1993/001512 patent/WO1994002483A1/en not_active Application Discontinuation
- 1993-07-20 YU YU50293A patent/YU50293A/sh unknown
-
1995
- 1995-01-18 BG BG99359A patent/BG99359A/bg unknown
- 1995-01-19 NO NO950202A patent/NO950202L/no unknown
- 1995-01-19 FI FI950229A patent/FI950229A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI950229A (fi) | 1995-03-10 |
| RU95104939A (ru) | 1996-10-27 |
| GB9215361D0 (en) | 1992-09-02 |
| HUT76787A (en) | 1997-11-28 |
| JPH08502037A (ja) | 1996-03-05 |
| SK7595A3 (en) | 1995-07-11 |
| HRP931066A2 (en) | 1995-12-31 |
| WO1994002483A1 (en) | 1994-02-03 |
| NZ254207A (en) | 1997-03-24 |
| CZ14995A3 (en) | 1995-10-18 |
| NO950202D0 (no) | 1995-01-19 |
| HU9500171D0 (en) | 1995-03-28 |
| ZA935213B (en) | 1995-01-19 |
| YU50293A (sh) | 1997-01-08 |
| PL307169A1 (en) | 1995-05-15 |
| NO950202L (no) | 1995-01-19 |
| BG99359A (bg) | 1995-11-30 |
| MX9304355A (es) | 1994-04-29 |
| KR950702563A (ko) | 1995-07-29 |
| EP0651750A1 (en) | 1995-05-10 |
| SI9300390A (en) | 1994-03-31 |
| CA2140662A1 (en) | 1994-02-03 |
| IL106385A0 (en) | 1993-11-15 |
| CN1088209A (zh) | 1994-06-22 |
| AU4579593A (en) | 1994-02-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI963283A (fi) | 4-asemasta heterosyklyylillä substituoituja kinatsoliinijohdannaisia, menetelmiä niiden valmistamiseksi ja niiden käyttö syöpälääkkeinä | |
| FI934220A (fi) | Piperidinderivat, framstaellning daerav och anvaendning daerav vid en terapi | |
| FI934373A (fi) | Fabrikationsprocess av komposittraod och kompositprodukter som faotts avnaemnda traoden | |
| FI930620A0 (fi) | Bensimidazolylderivat, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning | |
| FI945662A0 (fi) | Roerformad stomme, i synnerhet som hylselement och med hylselement foersedd stomme | |
| FI950229A (fi) | Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineina | |
| FI932625A0 (fi) | Anordning och foerfarande foer detektering av ytfel i laonga, i roerelse befintliga metallprodukter | |
| FI103666B1 (fi) | Menetelmä bifenyylijohdannaisen valmistamiseksi | |
| FI931291A (fi) | Indol- och indazolderivat foer behandling och foerebyggande av hjaernsjukdomar, deras framstaellning och anvaendning | |
| FI935829A0 (fi) | Anlaeggning och foerfarande foer uttnyttjning av braennbara aemnen, speciellt industri- och hushaollsavfall | |
| FI923855A (fi) | Katalysaattori ja sen valmistusmenetelmä | |
| FI934221A0 (fi) | Piperidinderivat, framstaellning och terapeutisk anvaendning daerav | |
| FI931682A (fi) | Tackykininreceptorantagonister, isokinoloner och deras framstaellning | |
| FI950874A0 (fi) | Uudet polyjoditetut yhdisteet, menetelmä niiden valmistamiseksi, niitä sisältävä varjoaine | |
| FI932750A (fi) | Kaoda nedbrytande svampar och preparation av dem | |
| FI935196A (fi) | Pyrrolderivat, framstaellning av dem och anvaendning av dem vid terapi | |
| FI875704A (fi) | Foerfarande och maskin foer skalning av potatis och liknande. | |
| FI935132A0 (fi) | Fenolisk resolfanerharts, foerfarande och tillverkning | |
| FI931159A (fi) | Dosaerosoler, som innehaoller som aktivt aemne flezelastin och med dettarelaterade strukturer | |
| FI950101A (fi) | 4-oksa-1-atsabisyklo 3,2,0 -7heptanoni-johdannaiset kasvainten vastaisina aineina | |
| FI934164A0 (fi) | Anordning foer att utfoera mig-svetsning pao en tredimensionell kurvad yta, och en svarvanordning foer automatisk formning av svetsskaoror | |
| FI924350A0 (fi) | Honungscellstruktur foer rensning av avgas och foerfarande foer framstaellning av denna. | |
| FI806U1 (fi) | Kombination av eldstad, roeklaeda och stekunderlag | |
| FI48U1 (fi) | Anordning foer ljus, vaser och dylika | |
| NO950061D0 (no) | 4-oksa-1-azabisyklo [3,2,0Å heptan-7-on-derivater som antitumormidler |