GB9027055D0 - Organic compounds - Google Patents

Organic compounds

Info

Publication number
GB9027055D0
GB9027055D0 GB909027055A GB9027055A GB9027055D0 GB 9027055 D0 GB9027055 D0 GB 9027055D0 GB 909027055 A GB909027055 A GB 909027055A GB 9027055 A GB9027055 A GB 9027055A GB 9027055 D0 GB9027055 D0 GB 9027055D0
Authority
GB
United Kingdom
Prior art keywords
organic compounds
4alkoxy
acid addition
addition salts
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB909027055A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Priority to GB909027055A priority Critical patent/GB9027055D0/en
Publication of GB9027055D0 publication Critical patent/GB9027055D0/en
Priority to HU913760A priority patent/HUT61729A/hu
Priority to ES91810954T priority patent/ES2093694T3/es
Priority to AT91810954T priority patent/ATE145201T1/de
Priority to DE69123124T priority patent/DE69123124T2/de
Priority to DK91810954.7T priority patent/DK0490823T3/da
Priority to EP91810954A priority patent/EP0490823B1/en
Priority to MYPI91002283A priority patent/MY129941A/en
Priority to FI915844A priority patent/FI915844A7/fi
Priority to MX9102502A priority patent/MX9102502A/es
Priority to IL10032891A priority patent/IL100328A/en
Priority to CS913757A priority patent/CZ281669B6/cs
Priority to NZ240936A priority patent/NZ240936A/xx
Priority to AU88985/91A priority patent/AU643575B2/en
Priority to SU915010401A priority patent/RU2060992C1/ru
Priority to CA002057524A priority patent/CA2057524A1/en
Priority to PT99775A priority patent/PT99775B/pt
Priority to PL91292738A priority patent/PL168329B1/pl
Priority to IE432591A priority patent/IE914325A1/en
Priority to US07/805,662 priority patent/US5177085A/en
Priority to KR1019910022728A priority patent/KR920012040A/ko
Priority to JP3328665A priority patent/JPH0764820B2/ja
Priority to ZA919858A priority patent/ZA919858B/xx
Priority to TW080109769A priority patent/TW201736B/zh
Priority to GR960403459T priority patent/GR3022034T3/el
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
GB909027055A 1990-12-13 1990-12-13 Organic compounds Pending GB9027055D0 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds
HU913760A HUT61729A (en) 1990-12-13 1991-12-02 Process for producing dihydroisoquinoline derivatives and pharmaceutical compositions comprising such compounds
ES91810954T ES2093694T3 (es) 1990-12-13 1991-12-09 Nuevos derivados de dihidro-isoquinoleina.
AT91810954T ATE145201T1 (de) 1990-12-13 1991-12-09 Dihydro-isoquinolinderivate
DE69123124T DE69123124T2 (de) 1990-12-13 1991-12-09 Dihydro-Isoquinolinderivate
DK91810954.7T DK0490823T3 (https=) 1990-12-13 1991-12-09
EP91810954A EP0490823B1 (en) 1990-12-13 1991-12-09 Dihydro-isoquinoline derivates
MYPI91002283A MY129941A (en) 1990-12-13 1991-12-10 Novel dihydro-isoquinoline derivatives
AU88985/91A AU643575B2 (en) 1990-12-13 1991-12-11 Isoquinoline derivatives
NZ240936A NZ240936A (en) 1990-12-13 1991-12-11 Alkoxy-substituted 1-phenyl-isoquinoline derivative and pharmaceutical compositions
MX9102502A MX9102502A (es) 1990-12-13 1991-12-11 Nuevos derivados de dihidro-isoquinolina y procedimiento para su preparacion.
IL10032891A IL100328A (en) 1990-12-13 1991-12-11 Dihydro isoquinoline derivatives their production and pharmaceutical compositions containing them
CS913757A CZ281669B6 (cs) 1990-12-13 1991-12-11 Nové dihydroisochinolinové deriváty
FI915844A FI915844A7 (fi) 1990-12-13 1991-12-11 Uusia dihydro-isokinoliinijohdannaisia
JP3328665A JPH0764820B2 (ja) 1990-12-13 1991-12-12 新規ジヒドロイソキノリン誘導体
PL91292738A PL168329B1 (pl) 1990-12-13 1991-12-12 Sposób wytwarzania nowych pochodnych dihydro-izochinoliny PL PL
CA002057524A CA2057524A1 (en) 1990-12-13 1991-12-12 Dihydro-isoquinoline derivatives
PT99775A PT99775B (pt) 1990-12-13 1991-12-12 Processo para a preparacao de novos derivados de di-hidroisoquinolina
SU915010401A RU2060992C1 (ru) 1990-12-13 1991-12-12 Производные дигидроизохинолинов и способ их получения
IE432591A IE914325A1 (en) 1990-12-13 1991-12-12 Novel dihydro-isoquinoline derivatives
US07/805,662 US5177085A (en) 1990-12-13 1991-12-12 Dihydro-isoquinoline derivatives, processes for their production, pharmaceutical compositions containing them, and their use in treating asthma
KR1019910022728A KR920012040A (ko) 1990-12-13 1991-12-12 신규의 디히드로-이소퀴놀린 유도체
ZA919858A ZA919858B (en) 1990-12-13 1991-12-13 Novel dihydro-isoquinoline derivatives.
TW080109769A TW201736B (https=) 1990-12-13 1991-12-13
GR960403459T GR3022034T3 (en) 1990-12-13 1996-12-13 Dihydro-isoquinoline derivates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Publications (1)

Publication Number Publication Date
GB9027055D0 true GB9027055D0 (en) 1991-02-06

Family

ID=10686945

Family Applications (1)

Application Number Title Priority Date Filing Date
GB909027055A Pending GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Country Status (25)

Country Link
US (1) US5177085A (https=)
EP (1) EP0490823B1 (https=)
JP (1) JPH0764820B2 (https=)
KR (1) KR920012040A (https=)
AT (1) ATE145201T1 (https=)
AU (1) AU643575B2 (https=)
CA (1) CA2057524A1 (https=)
CZ (1) CZ281669B6 (https=)
DE (1) DE69123124T2 (https=)
DK (1) DK0490823T3 (https=)
ES (1) ES2093694T3 (https=)
FI (1) FI915844A7 (https=)
GB (1) GB9027055D0 (https=)
GR (1) GR3022034T3 (https=)
HU (1) HUT61729A (https=)
IE (1) IE914325A1 (https=)
IL (1) IL100328A (https=)
MX (1) MX9102502A (https=)
MY (1) MY129941A (https=)
NZ (1) NZ240936A (https=)
PL (1) PL168329B1 (https=)
PT (1) PT99775B (https=)
RU (1) RU2060992C1 (https=)
TW (1) TW201736B (https=)
ZA (1) ZA919858B (https=)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212673D0 (en) * 1992-06-15 1992-07-29 Celltech Ltd Chemical compounds
GB9222253D0 (en) * 1992-10-23 1992-12-09 Celltech Ltd Chemical compounds
GB9226830D0 (en) * 1992-12-23 1993-02-17 Celltech Ltd Chemical compounds
US5622977A (en) * 1992-12-23 1997-04-22 Celltech Therapeutics Limited Tri-substituted (aryl or heteroaryl) derivatives and pharmaceutical compositions containing the same
GB9304919D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
GB9304920D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
GB9322828D0 (en) * 1993-11-05 1993-12-22 Sandoz Ltd Organic compounds
EP0738268B1 (en) * 1993-12-22 2004-03-03 Celltech R&D Limited Trisubstituted phenyl derivatives, processes for their preparation and their use as phosphodiesterase (type iv) inhibitors
GB9326173D0 (en) * 1993-12-22 1994-02-23 Celltech Ltd Chemical compounds and process
US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
GB9412573D0 (en) * 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9412571D0 (en) 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9412672D0 (en) * 1994-06-23 1994-08-10 Celltech Ltd Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
RU2161967C2 (ru) * 1994-08-18 2001-01-20 Дзе Проктер Энд Гэмбл Компани Соединения 7-(2-имидазолиниламино) хинолина, пригодные в качестве агонистов альфа-2-адренорецептора
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
EP0778263B1 (en) * 1994-08-22 2002-01-09 Welfide Corporation Benzene compound and medicinal use thereof
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
EP0799040B1 (en) * 1994-12-13 2003-08-20 Euroceltique S.A. Trisubstituted thioxanthines
US6268373B1 (en) * 1995-06-07 2001-07-31 Euro-Celtique S.A. Trisubstituted thioxanthines
GB9523267D0 (en) * 1995-11-14 1996-01-17 Sandoz Ltd Organic compounds
GB9523675D0 (en) * 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
GB9526243D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9526246D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9526245D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
WO1997034473A1 (en) * 1996-03-21 1997-09-25 The Trustees Of Columbia University In The City Of New York Craf1 (traf-3) isoforms and uses thereof
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
GB9608435D0 (en) * 1996-04-24 1996-06-26 Celltech Therapeutics Ltd Chemical compounds
GB9619284D0 (en) * 1996-09-16 1996-10-30 Celltech Therapeutics Ltd Chemical compounds
WO1998017636A1 (en) * 1996-10-22 1998-04-30 Ortho Pharmaceutical Corporation Phenylalaninol derivatives for the treatment of central nervous system disorders
GB9622363D0 (en) 1996-10-28 1997-01-08 Celltech Therapeutics Ltd Chemical compounds
GB9625184D0 (en) * 1996-12-04 1997-01-22 Celltech Therapeutics Ltd Chemical compounds
ID19155A (id) * 1996-12-13 1998-06-18 Tanabe Seiyaku Co Turunan-turunan piridin, pembuatannya dan intermediet untuk pembuatannya
EP0946523A1 (en) 1996-12-23 1999-10-06 Celltech Therapeutics Limited Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors
WO1998038168A1 (en) * 1997-02-27 1998-09-03 Tanabe Seiyaku Co., Ltd. Isoquinolinone derivatives, process for preparing the same, and their use as phosphodiesterase inhibitors
GB9705361D0 (en) 1997-03-14 1997-04-30 Celltech Therapeutics Ltd Chemical compounds
GB9713087D0 (en) * 1997-06-20 1997-08-27 Celltech Therapeutics Ltd Chemical compounds
PT998460E (pt) 1997-07-25 2004-07-30 Altana Pharma Ag Novos derivados de tetrazole
EP1023269A4 (en) * 1997-09-30 2001-06-27 Molecular Design Int BETA3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USE
IT1296985B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
IT1302677B1 (it) * 1998-10-15 2000-09-29 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
GB9914258D0 (en) 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
GB9924862D0 (en) 1999-10-20 1999-12-22 Celltech Therapeutics Ltd Chemical compounds
DE60125026T2 (de) * 2000-03-23 2007-06-28 Takeda Pharmaceutical Co. Ltd. Fluorisochinolinderivate, verfahren zu ihrer herstellung und ihre anwendung
CZ20031334A3 (cs) 2000-11-14 2003-09-17 Altana Pharma Ag Isochinolinové deriváty a jejich použití jako inhibitory
AU2002224835A1 (en) * 2000-11-14 2002-05-27 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Dihydroisoquinolines as novel phosphodiesterase inhibitors
US6593341B2 (en) 2001-03-29 2003-07-15 Molecular Design International, Inc. β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same
BR0209774A (pt) * 2001-05-29 2004-06-01 Schering Ag Pirimidinas inibidoras de cdk, sua preparação e aplicação como medicamento
DK1471054T3 (da) * 2002-01-11 2009-11-09 Daiichi Sankyo Co Ltd Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse
US7745180B2 (en) * 2002-04-24 2010-06-29 Hitachi Chemical Co., Ltd. Device and method for high-throughput quantification of mRNA from whole blood
RS20050117A (sr) * 2002-08-17 2007-06-04 Altana Pharma Ag., Novi benzonaftiridini
CA2495597A1 (en) * 2002-08-17 2004-03-04 Altana Pharma Ag Novel phenanthridines
ATE353217T1 (de) 2002-08-29 2007-02-15 Altana Pharma Ag 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
JP4587294B2 (ja) 2002-08-29 2010-11-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｄｅ４インヒビターとしての２−ヒドロキシ−６−フェニルフェナントリジン
US6596734B1 (en) 2002-10-11 2003-07-22 Molecular Design International, Inc. Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
RU2355686C2 (ru) * 2003-10-16 2009-05-20 Ф.Хоффманн-Ля Рош Аг Ингибиторы глутаминфруктозо-6-фосфатамидотрансферазы
CA2556086C (en) 2004-02-18 2014-04-01 Altana Pharma Ag Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (pde) 4 inhibitors
NZ549162A (en) 2004-02-24 2009-12-24 Sankyo Co Amino-pyrrol alcohol compounds
PL2589599T4 (pl) 2004-03-03 2015-06-30 Takeda Gmbh Nowe hydroksy-6-heteroarylofenantrydyny i ich zastosowanie jako inhibitorów PDE4
RU2281100C1 (ru) * 2005-01-11 2006-08-10 Общество с ограниченной ответственностью "Синтез-2000" Спазмолитическое средство
PL1856093T3 (pl) 2005-03-02 2010-05-31 Takeda Gmbh Chlorowodorek (2R,4aR,10bR)-6-(2,6-dimetoksy-pirydyn-3-ylo)-9-etoksy-8-metoksy-1,2,3,4,4a,10b-heksahydrofenantrydyn-2-olu
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
DK2681236T3 (en) 2011-03-01 2018-04-16 Synergy Pharmaceuticals Inc PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
WO2014131024A2 (en) 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
AU2014307803A1 (en) 2013-08-16 2016-03-10 Universiteit Maastricht Treatment of cognitive impairment with PDE4 inhibitor
EP4706758A3 (en) 2019-05-21 2026-05-06 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1400425A (en) * 1971-09-22 1975-07-16 Rolland Sa A Substituted 3-hydroxymethyl-isoquinolines and derivatives
PH25651A (en) * 1986-05-21 1991-08-21 Duphar Int Res New di, tetrahydroisoquinoline derivatives
HU196758B (en) * 1986-05-21 1989-01-30 Gyogyszerkutato Intezet Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
GB8800397D0 (en) * 1988-01-08 1988-02-10 Sandoz Ltd Improvements in/relating to organic compounds

Also Published As

Publication number Publication date
IL100328A (en) 1995-12-08
HU913760D0 (en) 1992-02-28
EP0490823A1 (en) 1992-06-17
IL100328A0 (en) 1992-09-06
DE69123124D1 (de) 1996-12-19
KR920012040A (ko) 1992-07-25
CA2057524A1 (en) 1992-06-14
FI915844A0 (fi) 1991-12-11
FI915844L (fi) 1992-06-14
EP0490823B1 (en) 1996-11-13
JPH04275276A (ja) 1992-09-30
CS375791A3 (en) 1992-06-17
PT99775B (pt) 1999-05-31
RU2060992C1 (ru) 1996-05-27
HUT61729A (en) 1993-03-01
AU643575B2 (en) 1993-11-18
MX9102502A (es) 1992-06-01
TW201736B (https=) 1993-03-11
FI915844A7 (fi) 1992-06-14
ATE145201T1 (de) 1996-11-15
CZ281669B6 (cs) 1996-12-11
IE914325A1 (en) 1992-06-17
MY129941A (en) 2007-05-31
ZA919858B (en) 1993-06-14
JPH0764820B2 (ja) 1995-07-12
DK0490823T3 (https=) 1997-02-17
GR3022034T3 (en) 1997-03-31
PL168329B1 (pl) 1996-02-29
ES2093694T3 (es) 1997-01-01
US5177085A (en) 1993-01-05
PT99775A (pt) 1992-11-30
DE69123124T2 (de) 1997-05-15
PL292738A1 (en) 1992-12-14
AU8898591A (en) 1992-06-18
NZ240936A (en) 1993-09-27

Similar Documents

Publication Publication Date Title
GB9027055D0 (en) Organic compounds
TW289020B (https=)
NO2004004I1 (no) Bortezomib eller en farmasøytisk akseptabel ester derav, eventuelt i form av et farmasøytisk akseptabelt salt derav
GB9309324D0 (en) Venzofuranyl-and-thiophenyl-alkanecarboxyclic acids derivatives
KR0148213B1 (en) Phenyla lkan(en)oic acid and pharmaceutical composition comprising the same
HUT47793A (en) Herbicide compositions containing 2,6-substituted-pyridine-carboxylic acid derivatives as active components and process for producing the active components
NO944531L (no) Diaminsalter av clavulansyre
CA2200742A1 (en) Quinoxaline derivatives useful in therapy
TW241264B (https=)
NO891679D0 (no) Fremgangsmaate for fremstilling av 5-klor-3-klorsulfonyl-2-tiofenkarbonsyreestere.
PT87563A (pt) Process for the preparation of vinylcephalosporins useful as medicaments
EP0127389A3 (en) N,n-diethyl-5-methyl-2h-1-benzothiopyrano-(4,3,2-cd)-indazole-2-ethanamine, compositions comprising the same and uses therefor
WO1995022544A3 (de) Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika
HU9202229D0 (en) Method for manufacturing new pharmaceutical preparatives containing 2-oxo-benzimidaazoline-1-carboxylic acid derivatives
AU6029090A (en) Improvements in or relating to organic compounds