GB861420A - Substituted phenothiazinyl piperazines - Google Patents
Substituted phenothiazinyl piperazinesInfo
- Publication number
- GB861420A GB861420A GB13199/59A GB1319959A GB861420A GB 861420 A GB861420 A GB 861420A GB 13199/59 A GB13199/59 A GB 13199/59A GB 1319959 A GB1319959 A GB 1319959A GB 861420 A GB861420 A GB 861420A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- methyl
- piperazine
- phenthiazinyl
- bromo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 phenothiazinyl piperazines Chemical class 0.000 title abstract 6
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- QOZKHOIGOQWTRS-UHFFFAOYSA-N 1-(2-bromoethoxy)hexane Chemical compound CCCCCCOCCBr QOZKHOIGOQWTRS-UHFFFAOYSA-N 0.000 abstract 1
- WNFMMHBDMMSQFG-UHFFFAOYSA-N 1-(5-ethoxypentyl)piperazine Chemical compound CCOCCCCCN1CCNCC1 WNFMMHBDMMSQFG-UHFFFAOYSA-N 0.000 abstract 1
- ZKDOQFPDSUOLGF-UHFFFAOYSA-N 1-bromo-3-chloro-2-methylpropane Chemical compound ClCC(C)CBr ZKDOQFPDSUOLGF-UHFFFAOYSA-N 0.000 abstract 1
- DRTWXURLAVHUQM-UHFFFAOYSA-N 1-bromo-5-ethoxypentane Chemical compound CCOCCCCCBr DRTWXURLAVHUQM-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000002440 hydroxy compounds Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 239000001294 propane Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K35/00—Rods, electrodes, materials, or media, for use in soldering, welding, or cutting
- B23K35/22—Rods, electrodes, materials, or media, for use in soldering, welding, or cutting characterised by the composition or nature of the material
- B23K35/24—Selection of soldering or welding materials proper
- B23K35/30—Selection of soldering or welding materials proper with the principal constituent melting at less than 1550 degrees C
- B23K35/3053—Fe as the principal constituent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE448276 | 1958-04-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB861420A true GB861420A (en) | 1961-02-22 |
Family
ID=3844344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB13199/59A Expired GB861420A (en) | 1958-04-19 | 1959-04-17 | Substituted phenothiazinyl piperazines |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE566958A (enrdf_load_stackoverflow) |
CH (1) | CH382169A (enrdf_load_stackoverflow) |
DE (1) | DE1131679B (enrdf_load_stackoverflow) |
GB (1) | GB861420A (enrdf_load_stackoverflow) |
NL (1) | NL100554C (enrdf_load_stackoverflow) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668671A (en) * | 1985-04-26 | 1987-05-26 | Smith Kline & French Laboratories Limited | Tricyclic derivatives and pharmaceutical use |
WO1998015546A1 (en) * | 1996-10-04 | 1998-04-16 | Novo Nordisk A/S | N-substituted azaheterocyclic compounds |
WO2002050050A1 (en) * | 2000-12-19 | 2002-06-27 | Ucb, S.A. | 2-(2-(4-((2r)-2-methyl-3-(10h-phenothiazin-10-yl)propyl)-1-piperazinyl)-ethoxy)ethanol, process for the preparation thereof, pharmaceutical compositions containing said compound and therapeutic uses thereof |
CN109053716A (zh) * | 2018-09-26 | 2018-12-21 | 暨明医药科技(苏州)有限公司 | 一种制备美托哌丙嗪的新工艺 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE558008A (enrdf_load_stackoverflow) * | 1956-06-21 |
-
0
- NL NL100554D patent/NL100554C/xx active
- BE BE566958D patent/BE566958A/xx unknown
-
1959
- 1959-04-17 DE DEM41207A patent/DE1131679B/de active Pending
- 1959-04-17 CH CH7218559A patent/CH382169A/fr unknown
- 1959-04-17 GB GB13199/59A patent/GB861420A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668671A (en) * | 1985-04-26 | 1987-05-26 | Smith Kline & French Laboratories Limited | Tricyclic derivatives and pharmaceutical use |
WO1998015546A1 (en) * | 1996-10-04 | 1998-04-16 | Novo Nordisk A/S | N-substituted azaheterocyclic compounds |
US6569849B1 (en) | 1996-10-04 | 2003-05-27 | Novo Nordisk A/S | N-Substituted azaheterocyclic compounds |
WO2002050050A1 (en) * | 2000-12-19 | 2002-06-27 | Ucb, S.A. | 2-(2-(4-((2r)-2-methyl-3-(10h-phenothiazin-10-yl)propyl)-1-piperazinyl)-ethoxy)ethanol, process for the preparation thereof, pharmaceutical compositions containing said compound and therapeutic uses thereof |
CN109053716A (zh) * | 2018-09-26 | 2018-12-21 | 暨明医药科技(苏州)有限公司 | 一种制备美托哌丙嗪的新工艺 |
Also Published As
Publication number | Publication date |
---|---|
NL100554C (enrdf_load_stackoverflow) | |
CH382169A (fr) | 1964-09-30 |
DE1131679B (de) | 1962-06-20 |
BE566958A (enrdf_load_stackoverflow) |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US2988551A (en) | Piperazine derivatives | |
GB842804A (en) | Preparation of substituted piperazines | |
GB850662A (en) | Substituted piperazines and processes for their production | |
GB861420A (en) | Substituted phenothiazinyl piperazines | |
GB991800A (en) | Two-component diazotype material | |
GB774883A (en) | Phenthiazine derivatives | |
GB819886A (en) | New phenthiazine derivatives and processes for their preparation | |
GB1045325A (en) | Thioxanthenes | |
GB954146A (en) | Improvements in or relating to steroid derivatives | |
GB688354A (en) | Improvements relating to compounds of the benzhydryl ether type | |
GB938646A (en) | New piperazine derivatives | |
GB874575A (en) | New basic ethers and a process for the production thereof | |
GB808636A (en) | Basically substituted heterocyclic compounds | |
GB712343A (en) | Improvements relating to 1, 4-disubstituted piperazines | |
GB841120A (en) | Improvements in or relating to piperidine compounds | |
GB945824A (en) | ªÏ-(pyridyl-3)-or ªÏ-(piperidyl-3)-propanol and derivatives thereof and processes for their manufacture | |
GB1056474A (en) | 4-amino-pyrazolone derivatives and process for the preparation thereof | |
GB1049769A (en) | Organic compounds containing an isocyclic and a heterocyclic non-aromatic ring and aprocess for the production of these compounds | |
GB974712A (en) | N-arylalkyl and n-arylalkenyl derivatives of 4-alkoxy-4-phenylpiperidines | |
GB794043A (en) | New quinoline derivatives | |
GB747418A (en) | New anaesthetic agents | |
GB1026927A (en) | Triphenylhaloethylenes | |
GB922957A (en) | New derivatives of pyrazine-carboxylic acid and process for the preparation thereof | |
GB853783A (en) | New piperazine derivatives and process for the preparation thereof | |
GB667116A (en) | Manufacture of biguanide derivatives |