GB1026927A - Triphenylhaloethylenes - Google Patents

Triphenylhaloethylenes

Info

Publication number
GB1026927A
GB1026927A GB235564A GB235564A GB1026927A GB 1026927 A GB1026927 A GB 1026927A GB 235564 A GB235564 A GB 235564A GB 235564 A GB235564 A GB 235564A GB 1026927 A GB1026927 A GB 1026927A
Authority
GB
United Kingdom
Prior art keywords
alkyl
compounds
triphenyldichloroethane
r1r2n
triphenylethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB235564A
Inventor
Frank Patrick Palopoli
Vernon John Feil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Priority to GB235564A priority Critical patent/GB1026927A/en
Priority to DER37109A priority patent/DE1226096B/en
Publication of GB1026927A publication Critical patent/GB1026927A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of formula <FORM:1026927/C2/1> where R1 and R2 are alkyl (1-4C) or with the N-atom are piperidino or morpholino, and R3 and R4 are hydrogen, halogen, alkyl or alkoxy (1-4C), or trifluoromethyl; acid addition salts thereof; and their preparation by chlorinating a corresponding triphenylethylene, and if necessary heating an intermediate triphenyldichloroethane at 50-150 DEG C. Starting materials additionally prepared are substituted 1 - (p - R1R2N - propyl - phenyl) - 1,2-diphenyl-ethanols. The compounds of the invention are gonadotrophin inhibitors and block cholesterol synthesis. Administration orally, parenterally and topically in conventional manner is mentioned.
GB235564A 1964-01-20 1964-01-20 Triphenylhaloethylenes Expired GB1026927A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB235564A GB1026927A (en) 1964-01-20 1964-01-20 Triphenylhaloethylenes
DER37109A DE1226096B (en) 1964-01-20 1964-01-31 Process for the preparation of triphenylhaloethylene compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB235564A GB1026927A (en) 1964-01-20 1964-01-20 Triphenylhaloethylenes

Publications (1)

Publication Number Publication Date
GB1026927A true GB1026927A (en) 1966-04-20

Family

ID=9738102

Family Applications (1)

Application Number Title Priority Date Filing Date
GB235564A Expired GB1026927A (en) 1964-01-20 1964-01-20 Triphenylhaloethylenes

Country Status (1)

Country Link
GB (1) GB1026927A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0793489A1 (en) * 1994-09-13 1997-09-10 Ramot University Authority For Applied Research & Industrial Development Ltd. Compositions for the treatment of skin disorders

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0793489A1 (en) * 1994-09-13 1997-09-10 Ramot University Authority For Applied Research & Industrial Development Ltd. Compositions for the treatment of skin disorders
EP0793489A4 (en) * 1994-09-13 2001-12-19 Univ Ramot Compositions for the treatment of skin disorders

Similar Documents

Publication Publication Date Title
GB943694A (en) 3-pyrazolidinone derivatives and their use as photographic developers
GB1120463A (en) Derivatives of 1,3-diazafluoranthene-1-oxide
ES330368A1 (en) Procedure for preparing N-alcohilamino-alcohilic derivatives of espirotetralinosuccinimidas and their salts. (Machine-translation by Google Translate, not legally binding)
GB1026927A (en) Triphenylhaloethylenes
GB1083902A (en) Pyrazinoyl guanidines
GB727151A (en) Improvements in derivatives of pyrimidine and methods of making the same
GB1022940A (en) Novel substituted quinolines and method of preparing the same
GB991800A (en) Two-component diazotype material
GB858140A (en) The preparation of new basic phenothiazine derivatives
GB954146A (en) Improvements in or relating to steroid derivatives
GB861420A (en) Substituted phenothiazinyl piperazines
GB1029221A (en) Triarylalkane derivatives
GB876022A (en) Hemioxonol dyes, processes for preparing them and photographic emulsions containing them
ES331427A1 (en) Procedure for the preparation of new condensed heterociclic compounds. (Machine-translation by Google Translate, not legally binding)
GB817231A (en) New derivatives of n-mono-benzhydryl-piperazine and process for the preparation thereof
ES319943A1 (en) Procedure for the obtaining of 3 &#39;, 4&#39;, 5&#39;-trimetoxy-3-aminoacrilofenona. (Machine-translation by Google Translate, not legally binding)
GB938646A (en) New piperazine derivatives
GB1067817A (en) Substituted piperazines
GB1031082A (en) Benzene derivatives
ES310920A1 (en) Procedure for obtaining heterociclic piperidinic compounds. (Machine-translation by Google Translate, not legally binding)
ES314975A1 (en) A procedure for the preparation of fluorene i-oxides- (1,9-ef) -1,4-diazepine. (Machine-translation by Google Translate, not legally binding)
ES295940A1 (en) A procedure for the preparation of compounds of trifenilohalo-ethylene (Machine-translation by Google Translate, not legally binding)
ES360860A1 (en) Procedure for the preparation of new derivatives of tiazepine. (Machine-translation by Google Translate, not legally binding)
GB1059898A (en) Basically-substituted 6,11-dihydro-dibenz-[b,e]-oxepin-6-ones
GB740307A (en) New amide-like derivatives of piperidine and process for their preparation