GB1059898A - Basically-substituted 6,11-dihydro-dibenz-[b,e]-oxepin-6-ones - Google Patents

Basically-substituted 6,11-dihydro-dibenz-[b,e]-oxepin-6-ones

Info

Publication number
GB1059898A
GB1059898A GB84566A GB84566A GB1059898A GB 1059898 A GB1059898 A GB 1059898A GB 84566 A GB84566 A GB 84566A GB 84566 A GB84566 A GB 84566A GB 1059898 A GB1059898 A GB 1059898A
Authority
GB
United Kingdom
Prior art keywords
formula
alkyl
oxepin
dibenz
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB84566A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1059898A publication Critical patent/GB1059898A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention comprises compounds of the formula <FORM:1059898/C2/1> wherein R1 is a hydrogen or halogen atom or a C1- 6 alkyl radical, R2 is a hydrogen atom or a C1- 6 alkyl radical and B is a dialkylamino, alkyl-aralkylamino, pyrrolidino, piperidino, morpholino, thiomorpholino or N-alkyl-piperazino radical; pharmaceutically - acceptable, non-toxic, acid-addition salts thereof; and a process for their preparation comprising reacting a dione of the formula <FORM:1059898/C2/2> with a Grinard compound of the formula <FORM:1059898/C2/3> wherein X represents a chlorine or bromine atom, and cyclizing the resulting compound of the formula <FORM:1059898/C2/4> or <FORM:1059898/C2/5> by splitting off one or two molecules of water, respectively.
GB84566A 1965-01-07 1966-01-07 Basically-substituted 6,11-dihydro-dibenz-[b,e]-oxepin-6-ones Expired GB1059898A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0044899 1965-01-07

Publications (1)

Publication Number Publication Date
GB1059898A true GB1059898A (en) 1967-02-22

Family

ID=7100257

Family Applications (1)

Application Number Title Priority Date Filing Date
GB84566A Expired GB1059898A (en) 1965-01-07 1966-01-07 Basically-substituted 6,11-dihydro-dibenz-[b,e]-oxepin-6-ones

Country Status (3)

Country Link
DE (1) DE1251331B (en)
FR (2) FR1463285A (en)
GB (1) GB1059898A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2119015A1 (en) * 1970-12-22 1972-08-04 Yoshitomi Pharmaceutical

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2119015A1 (en) * 1970-12-22 1972-08-04 Yoshitomi Pharmaceutical

Also Published As

Publication number Publication date
FR1463285A (en) 1966-12-23
FR5303M (en) 1967-08-16
DE1251331B (en) 1967-10-05

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