GB774883A - Phenthiazine derivatives - Google Patents
Phenthiazine derivativesInfo
- Publication number
- GB774883A GB774883A GB17971/55A GB1797155A GB774883A GB 774883 A GB774883 A GB 774883A GB 17971/55 A GB17971/55 A GB 17971/55A GB 1797155 A GB1797155 A GB 1797155A GB 774883 A GB774883 A GB 774883A
- Authority
- GB
- United Kingdom
- Prior art keywords
- atom
- methyl
- derivatives
- quaternary ammonium
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Abstract
The invention comprises phenthiazine derivatives of the formula: <FORM:0774883/IV(b)/1> and their acid addition salts and quaternary ammonium derivatives in which the -CH2-bridge is directly connected to a ring carbon atom of the piperidine nucleus, X represents a halogen (preferably chlorine) atom or an alkyl or alkoxy group containing not more than 4 carbon atoms or a phenyl or phenoxy group and R represents a hydrogen atom or an alkyl group containing not more than 4 carbon atoms or a benzyl group. Such compounds are obtained by the method of Specification 774,882. Preferred for therapeutic purposes are the hydrohalides and the quaternary ammonium salts. Bases specifically described are 3 - chloro -, 3-methyl asnd 3-methoxy-10-(1-methyl-3-piperidyl)-methylphenthiazines.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB333362X | 1954-06-21 | ||
GB160655X | 1955-06-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB774883A true GB774883A (en) | 1957-05-15 |
Family
ID=26251762
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB17971/55A Expired GB774883A (en) | 1954-06-21 | 1954-06-21 | Phenthiazine derivatives |
GB18213/54A Expired GB774882A (en) | 1954-06-21 | 1954-06-21 | Improvements in or relating to phenthiazine derivatives |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB18213/54A Expired GB774882A (en) | 1954-06-21 | 1954-06-21 | Improvements in or relating to phenthiazine derivatives |
Country Status (4)
Country | Link |
---|---|
CH (1) | CH333362A (en) |
DE (1) | DE1052403B (en) |
FR (1) | FR1171946A (en) |
GB (2) | GB774883A (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1100635B (en) * | 1958-04-22 | 1961-03-02 | Rhone Poulenc Sa | Process for the preparation of phenthiazine derivatives |
DE1092476B (en) * | 1958-04-24 | 1960-11-10 | Rhone Poulenc Sa | Process for the preparation of phenthiazine derivatives |
NL244514A (en) * | 1958-10-21 | |||
GB8912303D0 (en) * | 1989-05-27 | 1989-07-12 | Pfizer Ltd | Therapeutic agents |
US9504692B2 (en) | 2011-08-02 | 2016-11-29 | Helmholtz Zentrum Munchen, Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Selective inhibition of MALT1 protease by phenothiazine derivatives |
WO2022187568A1 (en) * | 2021-03-05 | 2022-09-09 | Monopteros Therapeutics, Inc. | (s)-mepazine salt forms, process of preparing, and formulations thereof |
-
1954
- 1954-06-21 GB GB17971/55A patent/GB774883A/en not_active Expired
- 1954-06-21 GB GB18213/54A patent/GB774882A/en not_active Expired
-
1955
- 1955-06-01 FR FR1171946D patent/FR1171946A/en not_active Expired
- 1955-06-20 DE DES44425A patent/DE1052403B/en active Pending
- 1955-06-20 CH CH333362D patent/CH333362A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB774882A (en) | 1957-05-15 |
CH333362A (en) | 1958-10-15 |
FR1171946A (en) | 1959-02-03 |
DE1052403B (en) | 1959-03-12 |
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