GB974712A - N-arylalkyl and n-arylalkenyl derivatives of 4-alkoxy-4-phenylpiperidines - Google Patents

N-arylalkyl and n-arylalkenyl derivatives of 4-alkoxy-4-phenylpiperidines

Info

Publication number
GB974712A
GB974712A GB10905/62A GB1090562A GB974712A GB 974712 A GB974712 A GB 974712A GB 10905/62 A GB10905/62 A GB 10905/62A GB 1090562 A GB1090562 A GB 1090562A GB 974712 A GB974712 A GB 974712A
Authority
GB
United Kingdom
Prior art keywords
alkoxy
prepared
unsaturated compound
phenylpiperidines
arylalkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10905/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Laboratorium C Janssen NV
Original Assignee
Research Laboratorium C Janssen NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Laboratorium C Janssen NV filed Critical Research Laboratorium C Janssen NV
Publication of GB974712A publication Critical patent/GB974712A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention comprises compounds of the general formula: <FORM:0974712/C1/1> wherein Y is a hydrogen or a fluorine atom or a methoxy group; X is a -CH2- or a -CH=CH-residue; n is a positive integer less than 4 and "lower alkyl" is a C1-4-alkyl group. The bases form salts with inorganic and organic acids (including ascorbic acid) and quaternary ammonium salts with esters of alkanols and aralkanols. The compounds of the invention may be prepared by reacting an appropriate aralkyl or aralkenyl halide with a 4-alkoxy-4-phenylpiperidine or by reducing a ketone of the formula <FORM:0974712/C1/2> to the alcohol and subsequently dehydrating this to the unsaturated compound, or by hydrogenation of the unsaturated compound (where n is less than 3). 2-(4-Fluorophenyl) -1- chloroethane is prepared from the ethanol and thionyl chloride. Specification 974,711 is referred to.
GB10905/62A 1961-03-22 1962-03-21 N-arylalkyl and n-arylalkenyl derivatives of 4-alkoxy-4-phenylpiperidines Expired GB974712A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9742861A 1961-03-22 1961-03-22

Publications (1)

Publication Number Publication Date
GB974712A true GB974712A (en) 1964-11-11

Family

ID=22263291

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10905/62A Expired GB974712A (en) 1961-03-22 1962-03-21 N-arylalkyl and n-arylalkenyl derivatives of 4-alkoxy-4-phenylpiperidines

Country Status (4)

Country Link
BE (1) BE615349A (en)
BR (1) BR6237376D0 (en)
DE (1) DE1289529B (en)
GB (1) GB974712A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4333942A (en) 1979-08-03 1982-06-08 Byk Gulden Lomberg Chemische Fabrik Gmbh Anti-depressant and analgesic 4-phenoxypiperidines

Also Published As

Publication number Publication date
BE615349A (en) 1962-09-20
BR6237376D0 (en) 1973-05-17
DE1289529B (en) 1969-02-20

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