GB747418A - New anaesthetic agents - Google Patents

New anaesthetic agents

Info

Publication number
GB747418A
GB747418A GB18417/53A GB1841753A GB747418A GB 747418 A GB747418 A GB 747418A GB 18417/53 A GB18417/53 A GB 18417/53A GB 1841753 A GB1841753 A GB 1841753A GB 747418 A GB747418 A GB 747418A
Authority
GB
United Kingdom
Prior art keywords
aniline
tri
isopropyl
chloroacetyl
anaesthetic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB18417/53A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cassella Farbwerke Mainkur AG
Original Assignee
Cassella Farbwerke Mainkur AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur AG filed Critical Cassella Farbwerke Mainkur AG
Publication of GB747418A publication Critical patent/GB747418A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

The invention comprises compounds of the formula <FORM:0747418/IV(a)/1> where each R is alkyl, aralkyl or cycloalkyl (or one may be hydrogen) or together they form a saturated ring with the N atom which may contain a further hetero atom, and R1 is -CH2- or -C2H4-. These are made by condensing chloroacetyl or a chloropropionyl chloride first with 2:4:6-tri-isopropyl-aniline and then with HNRR. Examples show the production of (1) N - chloroacetyl - 2:4:6 - tri - isopropyl - aniline and its condensation products with dimethylamine, diethylamine, ethylamine, n-butylamine, benzylamine, cyclohexylamine and morpholine; and (2) N-(b -chloropropionylamino) - 2:4:6-tri-isopropyl-aniline and its condensation product with piperidine. The hydrochlorides of the products are described. Specification 634,073 is referred to.
GB18417/53A 1952-07-05 1953-07-02 New anaesthetic agents Expired GB747418A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE747418X 1952-07-05

Publications (1)

Publication Number Publication Date
GB747418A true GB747418A (en) 1956-04-04

Family

ID=6648622

Family Applications (1)

Application Number Title Priority Date Filing Date
GB18417/53A Expired GB747418A (en) 1952-07-05 1953-07-02 New anaesthetic agents

Country Status (1)

Country Link
GB (1) GB747418A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1156814B (en) * 1957-10-31 1963-11-07 Astra Apotekarnes Kem Fab Process for the preparation of ª-morpholino-fatty acid anilides
GB2177695A (en) * 1985-07-15 1987-01-28 Roussel Lab Ltd Aminoalkylamide derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1156814B (en) * 1957-10-31 1963-11-07 Astra Apotekarnes Kem Fab Process for the preparation of ª-morpholino-fatty acid anilides
GB2177695A (en) * 1985-07-15 1987-01-28 Roussel Lab Ltd Aminoalkylamide derivatives
GB2177695B (en) * 1985-07-15 1989-07-19 Roussel Lab Ltd Aminoalkylamide derivatives

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