GB686135A - Improvements in cyclopentanophenanthrene derivatives and process for producing the same - Google Patents

Improvements in cyclopentanophenanthrene derivatives and process for producing the same

Info

Publication number
GB686135A
GB686135A GB21137/50A GB2113750A GB686135A GB 686135 A GB686135 A GB 686135A GB 21137/50 A GB21137/50 A GB 21137/50A GB 2113750 A GB2113750 A GB 2113750A GB 686135 A GB686135 A GB 686135A
Authority
GB
United Kingdom
Prior art keywords
allopregnane
producing
same
diol
amide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21137/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex SA
Original Assignee
Syntex SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex SA filed Critical Syntex SA
Publication of GB686135A publication Critical patent/GB686135A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

2 - Halo - allopregnane - 17a - ol - 3,20 - dione having the formula <FORM:0686135/IV (b)/1> wherein X is a chlorine or bromine atom, is produced by reacting allopregnane-3b ,17a -diol-20-one with an amide having the formula <FORM:0686135/IV (b)/2> wherein R is an aromatic or aliphatic radical and X is a chlorine or bromine atom, in the proportion of 1 mol. of allopregnane-3b , 17 a -diol-20-one to 2 mols. of the amide. As amides there may be used bromacetamide, bromotoluenesulphonamide, bromophthalimide, bromosuccinimide or chlorosuccinimide and the reaction is effected in a suitable solvent, e.g. tertiary-butyl alcohol. Specification 685,331 is referred to.
GB21137/50A 1949-09-19 1950-08-25 Improvements in cyclopentanophenanthrene derivatives and process for producing the same Expired GB686135A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US686135XA 1949-09-19 1949-09-19

Publications (1)

Publication Number Publication Date
GB686135A true GB686135A (en) 1953-01-21

Family

ID=22083646

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21137/50A Expired GB686135A (en) 1949-09-19 1950-08-25 Improvements in cyclopentanophenanthrene derivatives and process for producing the same

Country Status (1)

Country Link
GB (1) GB686135A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3057859A (en) * 1959-06-09 1962-10-09 British Drug Houses Ltd 4alpha-methyl-3-oxo-5alpha-steroids and a method for preparation of same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3057859A (en) * 1959-06-09 1962-10-09 British Drug Houses Ltd 4alpha-methyl-3-oxo-5alpha-steroids and a method for preparation of same

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