ES271722A1 - New steroid compounds, and processes for their preparation - Google Patents

New steroid compounds, and processes for their preparation

Info

Publication number
ES271722A1
ES271722A1 ES0271722A ES271722A ES271722A1 ES 271722 A1 ES271722 A1 ES 271722A1 ES 0271722 A ES0271722 A ES 0271722A ES 271722 A ES271722 A ES 271722A ES 271722 A1 ES271722 A1 ES 271722A1
Authority
ES
Spain
Prior art keywords
estra
hydroxy
preparation
processes
steroid compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0271722A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Francais de Chimiotherapie SA
Laboratoires Francaise de Chimiotherapie
Original Assignee
Laboratoires Francais de Chimiotherapie SA
Laboratoires Francaise de Chimiotherapie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Francais de Chimiotherapie SA, Laboratoires Francaise de Chimiotherapie filed Critical Laboratoires Francais de Chimiotherapie SA
Publication of ES271722A1 publication Critical patent/ES271722A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 17a -ethinyl-17b hydroxy - estra - b (10),9(11) - dien-3-one and a process for the preparation thereof by reacting 17a - ethynyl - 17b - hydroxy-estra-4,9(10)-dien3-one with a secondary amine so as to form the corresponding 3-enamino-17a -ethynyl-17b hydroxy - estra - 3,5(10),9(11) - triene of the formula: <FORM:0919434/IV (b)/1> (where R and R1 are alkyl groups, which may be the same or different, or together with the nitrogen atom constitute a heterocyclic ring containing nitrogen or both nitrogen and oxygen) and the latter is subjected to hydrolysis in an acid medium so as to yield the desired 17a -ethinyl-17b -hydroxy-estra-5(10), 9(11)-dien-3-one. As secondary amine there may be used pyrrolidine, piperidine or morpholine. Hydrolysis may be effected with formic or acetic acids.
ES0271722A 1960-11-04 1961-11-03 New steroid compounds, and processes for their preparation Expired ES271722A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR843044A FR1363115A (en) 1960-11-04 1960-11-04 Novel ethynylated steroid derivative and method of preparation

Publications (1)

Publication Number Publication Date
ES271722A1 true ES271722A1 (en) 1962-01-01

Family

ID=8742086

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0271722A Expired ES271722A1 (en) 1960-11-04 1961-11-03 New steroid compounds, and processes for their preparation

Country Status (5)

Country Link
BE (1) BE609881A (en)
CH (1) CH395979A (en)
ES (1) ES271722A1 (en)
FR (1) FR1363115A (en)
GB (1) GB919434A (en)

Also Published As

Publication number Publication date
BE609881A (en) 1962-05-03
GB919434A (en) 1963-02-27
CH395979A (en) 1965-07-31
FR1363115A (en) 1964-06-12

Similar Documents

Publication Publication Date Title
ES269420A1 (en) Novel estradienes and preparation thereof
ES271722A1 (en) New steroid compounds, and processes for their preparation
GB1042480A (en) Substituted pyridyl coumarins
GB914525A (en) New n-substituted carbamic acid esters and a process for the production thereof
ES285236A1 (en) Procedure for the preparation of penicillins (Machine-translation by Google Translate, not legally binding)
GB930676A (en) Process for the preparation of 20-alkylamino steroid derivatives and novel 20-alkylamino steroid derivatives prepared thereby
ES273089A1 (en) Process of making nu-acyl derivatives of 6-amino-penicillanic acid
ES236513A1 (en) Salts of steroidal amino acid esters
ES307983A1 (en) Procedure for the preparation of new amidas of ariloxyacetic acid. (Machine-translation by Google Translate, not legally binding)
GB771151A (en) Method for the preparation of aminoacyl-anilides
ES275091A1 (en) Process for the production of dibenzoazepine derivatives
SE7710337L (en) PROCEDURE FOR THE PREPARATION OF 9,11-HALOGENERATED STEROIDS
GB983607A (en) Novel 4,5-seco-steroid compounds and methods for the formation thereof
GB879954A (en) Process for the manufacture of tertiary alkylamine phthalazones
GB1098349A (en) Improvements in or relating to the preparation of p-alkoxy-phenyl-alkylene carboxylic acids
GB686135A (en) Improvements in cyclopentanophenanthrene derivatives and process for producing the same
GB1215124A (en) PROCESS FOR THE PRODUCTION OF DERIVATIVES OF o-ALKOXYPHENOLS
GB937184A (en) 8-azabicyclo-octane-2,4-dione derivatives
ES236450A1 (en) Procedure for the obtaining of new derivatives of pepiracine (Machine-translation by Google Translate, not legally binding)
ES289046A1 (en) A procedure for preparing new derivatives of 6-methyl and 1,6-dimethyl-8- (alpha-hydroxy-alkyl) -ergoline i (Machine-translation by Google Translate, not legally binding)
GB773027A (en) Improvements in or relating to steroids and the manufacture thereof
ES303113A1 (en) Procedure for preparing steroid ketones and their derivatives. (Machine-translation by Google Translate, not legally binding)
GB889231A (en) Improvements in or relating to penicillins
ES260554A1 (en) Procedure for the manufacture of hydrazides of carboxylic acid disustitute in n1 and n2 (Machine-translation by Google Translate, not legally binding)
ES230580A1 (en) A procedure for preparing alcohyl transhexahidrotereftalate and steroid hormone (Machine-translation by Google Translate, not legally binding)