ES303113A1 - Procedure for preparing steroid ketones and their derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for preparing steroid ketones and their derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES303113A1
ES303113A1 ES0303113A ES303113A ES303113A1 ES 303113 A1 ES303113 A1 ES 303113A1 ES 0303113 A ES0303113 A ES 0303113A ES 303113 A ES303113 A ES 303113A ES 303113 A1 ES303113 A1 ES 303113A1
Authority
ES
Spain
Prior art keywords
group
ring
translation
derivatives
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0303113A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES303113A1 publication Critical patent/ES303113A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)

Abstract

Procedure for preparing steroid ketones and their derivatives, especially a structured steroid ketone ** (See formula) ** characterized in that each R group is hydrogen or an alkyl group, R1 is a saturated alkyl group having at least 2 carbon atoms, R2 is a halogenoalkynyl group trans to R1, R3 is hydrogen or an alkyl or acyl group, Q is a methylenic or ethylenic group, the substituents on the tertiary carbon atoms of ring C are in the trans-anti-trans configuration and ring A contains an atylenic bond terminating in position 5, a process in which a hydrolyze is structure steroid ketone derivative ** (See formula) ** where R, R1, R2, R3, Q and the configuration of ring C are as indicated above, group X contains an organic radical linked to ring A by oxygen, sulfur or nitrogen, there is unsaturation in ring A or in ring B and group X and unsaturation form an arrangement of atoms such that acid hydrolysis can convert it into a 4,5-ethylenic 3-ketone. (Machine-translation by Google Translate, not legally binding)
ES0303113A 1963-08-14 1964-08-13 Procedure for preparing steroid ketones and their derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES303113A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3206463A GB1100441A (en) 1963-08-14 1963-08-14 13-alkyl 17-halogenoalkynyl-steroid 3-ketones and their derivatives

Publications (1)

Publication Number Publication Date
ES303113A1 true ES303113A1 (en) 1965-01-01

Family

ID=10332630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0303113A Expired ES303113A1 (en) 1963-08-14 1964-08-13 Procedure for preparing steroid ketones and their derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
ES (1) ES303113A1 (en)
GB (1) GB1100441A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984476A (en) * 1974-10-18 1976-10-05 Andor Furst D-homo-19-norsteroids

Also Published As

Publication number Publication date
GB1100441A (en) 1968-01-24

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