ES290275A2 - Procedure for preparing new compounds for 6-methyl and 1,6-dimethyl-er-golina ii (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for preparing new compounds for 6-methyl and 1,6-dimethyl-er-golina ii (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES290275A2
ES290275A2 ES290275A ES290275A ES290275A2 ES 290275 A2 ES290275 A2 ES 290275A2 ES 290275 A ES290275 A ES 290275A ES 290275 A ES290275 A ES 290275A ES 290275 A2 ES290275 A2 ES 290275A2
Authority
ES
Spain
Prior art keywords
methyl
dimethyl
new compounds
translation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES290275A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farm Italia
Pfizer Italia SRL
Original Assignee
Farm Italia
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farm Italia, Farmaceutici Italia SpA filed Critical Farm Italia
Publication of ES290275A2 publication Critical patent/ES290275A2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Improvements in the object of the main patent No. 289,641, by "procedure for preparing new compounds of 6-methyl- and 1,6-dimethyl-ergoline II", and especially new compounds of 6-methyl- and 1 , 6-dimethyl-8-hydroxymethyl-ergoline I, of the following structural formula: ** (See formula) ** where R is hydrogen or methyl and R 'is the radical of an organic acid aliphatic, cycloaliphatic, aromatic or heterocyclic with 3 to 10 carbon atoms, characterized in that a compound taken in the group consisting of dihydro-lysergol I and 1-methyl-dihydro-lysergol I is esterified with the anhydride or the chloride of an organic acid aliphatic, cycloaliphatic, aromatic or heterocyclic with to 10 carbon atoms, in the presence or absence of tertiary amines, such as pyridine, diethyloniline, triethylamine and the like. (Machine-translation by Google Translate, not legally binding)
ES290275A 1962-07-26 1963-07-05 Procedure for preparing new compounds for 6-methyl and 1,6-dimethyl-er-golina ii (Machine-translation by Google Translate, not legally binding) Expired ES290275A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1506562 1962-07-26

Publications (1)

Publication Number Publication Date
ES290275A2 true ES290275A2 (en) 1964-03-01

Family

ID=11146222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES290275A Expired ES290275A2 (en) 1962-07-26 1963-07-05 Procedure for preparing new compounds for 6-methyl and 1,6-dimethyl-er-golina ii (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
AT (1) AT243993B (en)
BE (1) BE635411A (en)
CH (1) CH454890A (en)
DE (1) DE1470248A1 (en)
DK (1) DK104939C (en)
ES (1) ES290275A2 (en)
GB (1) GB1048555A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1094965B (en) * 1978-04-05 1985-08-10 Corvi Mora E LISERGOL DERIVATION PREPARATION PROCEDURE
DE3001752A1 (en) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin METHOD FOR PRODUCING 8 (ALPHA) SUBSTITUTED 6-METHYLERGOLINES

Also Published As

Publication number Publication date
GB1048555A (en) 1966-11-16
AT243993B (en) 1965-12-10
DK104939C (en) 1966-07-25
BE635411A (en) 1963-11-18
DE1470248A1 (en) 1969-10-09
CH454890A (en) 1968-04-30

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