GB494183A - Improvements in the manufacture and production of aminoquinaldines - Google Patents
Improvements in the manufacture and production of aminoquinaldinesInfo
- Publication number
- GB494183A GB494183A GB1510037A GB1510037A GB494183A GB 494183 A GB494183 A GB 494183A GB 1510037 A GB1510037 A GB 1510037A GB 1510037 A GB1510037 A GB 1510037A GB 494183 A GB494183 A GB 494183A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminoquinaldine
- hydroxyquinaldine
- yield
- ammonia
- methylquinaldine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Quinoline Compounds (AREA)
Abstract
8-Aminoquinaldine and its nuclear substitution products are obtained by heating 8-hydroxyquinaldine or its ethers or esters, or the substitution products of any of these compounds, with ammonia (or a reagent which yields ammonia) at about 150-220 DEG C. in the presence of a sulphite or bisulphite or in the absence of oxygen or a gas containing oxygen. In the examples: (1) 8-hydroxyquinaldine is heated with ammonia and aqueous sodium bisulphite solution to yield 8-aminoquinaldine; (2) 8 - methoxyquinaldine and 8 - acetoxyquinaldine are treated as in example 1 to yield 8-aminoquinaldine; (3) 8-hydroxyquinaldine is heated with urea in an atmosphere of nitrogen; 8 - aminoquinaldine is again obtained; (4) 8 - hydroxy - 5 - methylquinaldine is treated as in example 1 to yield 8-amino-5-methylquinaldine. Specification 395,063 is referred to.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1510037A GB494183A (en) | 1937-05-31 | 1937-05-31 | Improvements in the manufacture and production of aminoquinaldines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1510037A GB494183A (en) | 1937-05-31 | 1937-05-31 | Improvements in the manufacture and production of aminoquinaldines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB494183A true GB494183A (en) | 1938-10-21 |
Family
ID=10053033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1510037A Expired GB494183A (en) | 1937-05-31 | 1937-05-31 | Improvements in the manufacture and production of aminoquinaldines |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB494183A (en) |
-
1937
- 1937-05-31 GB GB1510037A patent/GB494183A/en not_active Expired
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