GB2597398B - Multivalent binding composition for nucleic acid analysis - Google Patents
Multivalent binding composition for nucleic acid analysis Download PDFInfo
- Publication number
- GB2597398B GB2597398B GB2115667.4A GB202115667A GB2597398B GB 2597398 B GB2597398 B GB 2597398B GB 202115667 A GB202115667 A GB 202115667A GB 2597398 B GB2597398 B GB 2597398B
- Authority
- GB
- United Kingdom
- Prior art keywords
- nucleic acid
- acid analysis
- binding composition
- multivalent binding
- multivalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/157—A reaction step characterised by the number of molecules incorporated or released
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/149—Particles, e.g. beads
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962852876P | 2019-05-24 | 2019-05-24 | |
| US201962897172P | 2019-09-06 | 2019-09-06 | |
| US16/579,794 US10768173B1 (en) | 2019-09-06 | 2019-09-23 | Multivalent binding composition for nucleic acid analysis |
| PCT/US2020/034409 WO2020243017A1 (en) | 2019-05-24 | 2020-05-22 | Multivalent binding composition for nucleic acid analysis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB202115667D0 GB202115667D0 (en) | 2021-12-15 |
| GB2597398A GB2597398A (en) | 2022-01-26 |
| GB2597398B true GB2597398B (en) | 2024-03-06 |
Family
ID=73554179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2115667.4A Active GB2597398B (en) | 2019-05-24 | 2020-05-22 | Multivalent binding composition for nucleic acid analysis |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3947731A4 (https=) |
| JP (2) | JP7542000B2 (https=) |
| KR (3) | KR102823471B1 (https=) |
| CN (1) | CN113939601A (https=) |
| AU (3) | AU2020285657B2 (https=) |
| CA (1) | CA3137120A1 (https=) |
| DE (1) | DE112020002516B4 (https=) |
| GB (1) | GB2597398B (https=) |
| IL (3) | IL316901A (https=) |
| SG (1) | SG11202112049VA (https=) |
| WO (1) | WO2020243017A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019241305A1 (en) | 2018-06-12 | 2019-12-19 | Element Biosciences, Inc. | Improved reverse transcriptase for nucleic acid sequencing |
| US10768173B1 (en) | 2019-09-06 | 2020-09-08 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US10704094B1 (en) | 2018-11-14 | 2020-07-07 | Element Biosciences, Inc. | Multipart reagents having increased avidity for polymerase binding |
| WO2020102766A2 (en) | 2018-11-15 | 2020-05-22 | Element Biosciences, Inc. | Methods for generating circular nucleic acid molecules |
| AU2019392932B2 (en) | 2018-12-07 | 2023-11-02 | Element Biosciences, Inc. | Flow cell device and use thereof |
| US12313627B2 (en) | 2019-05-01 | 2025-05-27 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US12391929B2 (en) | 2019-05-24 | 2025-08-19 | Element Biosciences, Inc. | Polymerase-nucleotide conjugates for sequencing by trapping |
| US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US11060138B1 (en) | 2020-01-17 | 2021-07-13 | Element Biosciences, Inc. | Nucleic acid sequencing systems |
| US11198121B1 (en) | 2020-06-10 | 2021-12-14 | Element Biosciences, Inc. | Flow cell systems and devices |
| GB2599729A (en) * | 2020-10-12 | 2022-04-13 | Sumitomo Chemical Co | Method comprising light emitting marker |
| CA3196800A1 (en) | 2020-10-30 | 2022-05-05 | Element Biosciences, Inc. | Reagents for massively parallel nucleic acid sequencing |
| AU2022316142A1 (en) | 2021-07-21 | 2024-02-22 | Element Biosciences, Inc. | Optical systems for nucleic acid sequencing and methods thereof |
| KR20230153706A (ko) | 2022-04-29 | 2023-11-07 | 연세대학교 산학협력단 | 핵산의 검출 또는 분리용 조성물 및 이를 이용한 핵산의 검출 또는 분리 방법 |
| EP4573213A1 (en) | 2022-08-15 | 2025-06-25 | Element Biosciences, Inc. | Spatially resolved surface capture of nucleic acids |
| CN116024315B (zh) * | 2022-11-30 | 2025-09-09 | 温州医科大学 | 一种基于链置换反应的多价双锁钥系统及其在核苷酸多态性检测中的应用 |
| WO2026080904A2 (en) | 2024-10-11 | 2026-04-16 | Element Biosciences, Inc. | Systems and methods for performing dna sequencing |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005111240A2 (en) * | 2004-04-30 | 2005-11-24 | Li-Cor, Inc. | Field-switch sequencing |
| WO2009073201A2 (en) * | 2007-12-04 | 2009-06-11 | Pacific Biosciences Of California, Inc. | Alternate labeling strategies for single molecule sequencing |
| US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
| US20100093992A1 (en) * | 2004-11-05 | 2010-04-15 | Dmitry Cherkasov | Macromolecular Nucleotide Compounds and Methods for Using the Same |
| WO2012027625A2 (en) * | 2010-08-25 | 2012-03-01 | Pacific Biosciences Of California, Inc. | Scaffold-based polymerase enzyme substrates |
| WO2013123258A1 (en) * | 2012-02-15 | 2013-08-22 | Pacific Biosciences Of California, Inc. | Polymerase enzyme substrates with protein shield |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| WO2012150035A1 (de) * | 2011-05-04 | 2012-11-08 | Genovoxx Gmbh | Nukleosid-triphosphat-konjugate und methoden zu deren anwendung |
| EP3589752B1 (en) | 2017-01-26 | 2021-05-19 | QIAGEN GmbH | Method for generating a sequencing library |
| WO2018144854A1 (en) | 2017-02-02 | 2018-08-09 | Caris Science, Inc. | Targeted oligonucleotides |
-
2020
- 2020-05-22 IL IL316901A patent/IL316901A/en unknown
- 2020-05-22 WO PCT/US2020/034409 patent/WO2020243017A1/en not_active Ceased
- 2020-05-22 KR KR1020237040302A patent/KR102823471B1/ko active Active
- 2020-05-22 KR KR1020217037728A patent/KR102607124B1/ko active Active
- 2020-05-22 CA CA3137120A patent/CA3137120A1/en active Pending
- 2020-05-22 EP EP20815612.5A patent/EP3947731A4/en active Pending
- 2020-05-22 CN CN202080042516.6A patent/CN113939601A/zh active Pending
- 2020-05-22 IL IL301380A patent/IL301380B2/en unknown
- 2020-05-22 AU AU2020285657A patent/AU2020285657B2/en active Active
- 2020-05-22 JP JP2021561845A patent/JP7542000B2/ja active Active
- 2020-05-22 SG SG11202112049VA patent/SG11202112049VA/en unknown
- 2020-05-22 GB GB2115667.4A patent/GB2597398B/en active Active
- 2020-05-22 KR KR1020257019970A patent/KR20250096873A/ko active Pending
- 2020-05-22 DE DE112020002516.0T patent/DE112020002516B4/de active Active
-
2021
- 2021-10-24 IL IL287528A patent/IL287528B2/en unknown
-
2022
- 2022-12-22 AU AU2022291540A patent/AU2022291540B2/en active Active
-
2024
- 2024-08-16 JP JP2024137063A patent/JP2024174880A/ja active Pending
-
2025
- 2025-01-20 AU AU2025200380A patent/AU2025200380A1/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
| WO2005111240A2 (en) * | 2004-04-30 | 2005-11-24 | Li-Cor, Inc. | Field-switch sequencing |
| US20100093992A1 (en) * | 2004-11-05 | 2010-04-15 | Dmitry Cherkasov | Macromolecular Nucleotide Compounds and Methods for Using the Same |
| WO2009073201A2 (en) * | 2007-12-04 | 2009-06-11 | Pacific Biosciences Of California, Inc. | Alternate labeling strategies for single molecule sequencing |
| WO2012027625A2 (en) * | 2010-08-25 | 2012-03-01 | Pacific Biosciences Of California, Inc. | Scaffold-based polymerase enzyme substrates |
| WO2013123258A1 (en) * | 2012-02-15 | 2013-08-22 | Pacific Biosciences Of California, Inc. | Polymerase enzyme substrates with protein shield |
Non-Patent Citations (2)
| Title |
|---|
| Anderson, J P. Et al "Flurescent Structural DNA Nanoballs Functionalized with Phospate - Lineked Nucleotide Triphosphates" Nano Letters 2010 10(3): 788-792. doi: 10.1021/nl9039718. Abstract, second last paragraph, Fig 3A * |
| Technology Spotlight: Illumina Sequencing, 2010, downloaded form https://www.illumina.com/documents/products/techspotlights/techspotlight_sequencing. pdf on 31/07.2020 * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20250096873A (ko) | 2025-06-27 |
| JP7542000B2 (ja) | 2024-08-29 |
| AU2022291540B2 (en) | 2024-11-14 |
| IL301380B1 (en) | 2025-01-01 |
| IL287528B1 (en) | 2023-04-01 |
| IL316901A (en) | 2025-01-01 |
| SG11202112049VA (en) | 2021-12-30 |
| IL301380A (en) | 2023-05-01 |
| DE112020002516T5 (de) | 2022-03-24 |
| CA3137120A1 (en) | 2020-12-03 |
| EP3947731A4 (en) | 2022-06-29 |
| CN113939601A (zh) | 2022-01-14 |
| JP2022535187A (ja) | 2022-08-05 |
| IL301380B2 (en) | 2025-05-01 |
| IL287528B2 (en) | 2023-08-01 |
| IL287528A (en) | 2021-12-01 |
| DE112020002516B4 (de) | 2025-03-13 |
| EP3947731A1 (en) | 2022-02-09 |
| KR20230165871A (ko) | 2023-12-05 |
| AU2025200380A1 (en) | 2025-02-06 |
| GB202115667D0 (en) | 2021-12-15 |
| KR102823471B1 (ko) | 2025-06-19 |
| KR20210144929A (ko) | 2021-11-30 |
| AU2020285657A1 (en) | 2021-11-18 |
| WO2020243017A1 (en) | 2020-12-03 |
| KR102607124B1 (ko) | 2023-11-29 |
| AU2020285657B2 (en) | 2022-10-06 |
| AU2022291540A1 (en) | 2023-02-02 |
| JP2024174880A (ja) | 2024-12-17 |
| GB2597398A (en) | 2022-01-26 |
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