KR102823471B1 - 핵산 분석을 위한 다가 결합 조성물 - Google Patents
핵산 분석을 위한 다가 결합 조성물 Download PDFInfo
- Publication number
- KR102823471B1 KR102823471B1 KR1020237040302A KR20237040302A KR102823471B1 KR 102823471 B1 KR102823471 B1 KR 102823471B1 KR 1020237040302 A KR1020237040302 A KR 1020237040302A KR 20237040302 A KR20237040302 A KR 20237040302A KR 102823471 B1 KR102823471 B1 KR 102823471B1
- Authority
- KR
- South Korea
- Prior art keywords
- nucleotide
- nucleic acid
- delete delete
- binding
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/101—DNA polymerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/157—A reaction step characterised by the number of molecules incorporated or released
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/149—Particles, e.g. beads
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020257019970A KR20250096873A (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962852876P | 2019-05-24 | 2019-05-24 | |
| US62/852,876 | 2019-05-24 | ||
| US201962897172P | 2019-09-06 | 2019-09-06 | |
| US62/897,172 | 2019-09-06 | ||
| US16/579,794 | 2019-09-23 | ||
| US16/579,794 US10768173B1 (en) | 2019-09-06 | 2019-09-23 | Multivalent binding composition for nucleic acid analysis |
| PCT/US2020/034409 WO2020243017A1 (en) | 2019-05-24 | 2020-05-22 | Multivalent binding composition for nucleic acid analysis |
| KR1020217037728A KR102607124B1 (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217037728A Division KR102607124B1 (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257019970A Division KR20250096873A (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20230165871A KR20230165871A (ko) | 2023-12-05 |
| KR102823471B1 true KR102823471B1 (ko) | 2025-06-19 |
Family
ID=73554179
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237040302A Active KR102823471B1 (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
| KR1020217037728A Active KR102607124B1 (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
| KR1020257019970A Pending KR20250096873A (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217037728A Active KR102607124B1 (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
| KR1020257019970A Pending KR20250096873A (ko) | 2019-05-24 | 2020-05-22 | 핵산 분석을 위한 다가 결합 조성물 |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3947731A4 (https=) |
| JP (2) | JP7542000B2 (https=) |
| KR (3) | KR102823471B1 (https=) |
| CN (1) | CN113939601A (https=) |
| AU (3) | AU2020285657B2 (https=) |
| CA (1) | CA3137120A1 (https=) |
| DE (1) | DE112020002516B4 (https=) |
| GB (1) | GB2597398B (https=) |
| IL (3) | IL316901A (https=) |
| SG (1) | SG11202112049VA (https=) |
| WO (1) | WO2020243017A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019241305A1 (en) | 2018-06-12 | 2019-12-19 | Element Biosciences, Inc. | Improved reverse transcriptase for nucleic acid sequencing |
| US10768173B1 (en) | 2019-09-06 | 2020-09-08 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US10704094B1 (en) | 2018-11-14 | 2020-07-07 | Element Biosciences, Inc. | Multipart reagents having increased avidity for polymerase binding |
| WO2020102766A2 (en) | 2018-11-15 | 2020-05-22 | Element Biosciences, Inc. | Methods for generating circular nucleic acid molecules |
| AU2019392932B2 (en) | 2018-12-07 | 2023-11-02 | Element Biosciences, Inc. | Flow cell device and use thereof |
| US12313627B2 (en) | 2019-05-01 | 2025-05-27 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US12391929B2 (en) | 2019-05-24 | 2025-08-19 | Element Biosciences, Inc. | Polymerase-nucleotide conjugates for sequencing by trapping |
| US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
| US11060138B1 (en) | 2020-01-17 | 2021-07-13 | Element Biosciences, Inc. | Nucleic acid sequencing systems |
| US11198121B1 (en) | 2020-06-10 | 2021-12-14 | Element Biosciences, Inc. | Flow cell systems and devices |
| GB2599729A (en) * | 2020-10-12 | 2022-04-13 | Sumitomo Chemical Co | Method comprising light emitting marker |
| CA3196800A1 (en) | 2020-10-30 | 2022-05-05 | Element Biosciences, Inc. | Reagents for massively parallel nucleic acid sequencing |
| AU2022316142A1 (en) | 2021-07-21 | 2024-02-22 | Element Biosciences, Inc. | Optical systems for nucleic acid sequencing and methods thereof |
| KR20230153706A (ko) | 2022-04-29 | 2023-11-07 | 연세대학교 산학협력단 | 핵산의 검출 또는 분리용 조성물 및 이를 이용한 핵산의 검출 또는 분리 방법 |
| EP4573213A1 (en) | 2022-08-15 | 2025-06-25 | Element Biosciences, Inc. | Spatially resolved surface capture of nucleic acids |
| CN116024315B (zh) * | 2022-11-30 | 2025-09-09 | 温州医科大学 | 一种基于链置换反应的多价双锁钥系统及其在核苷酸多态性检测中的应用 |
| WO2026080904A2 (en) | 2024-10-11 | 2026-04-16 | Element Biosciences, Inc. | Systems and methods for performing dna sequencing |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050158761A1 (en) | 1999-05-19 | 2005-07-21 | Jonas Korlach | Method for sequencing nucleic acid molecules |
| WO2018137826A1 (en) | 2017-01-26 | 2018-08-02 | Qiagen Gmbh | Method for enriching template nucleic acids |
| WO2018144854A1 (en) | 2017-02-02 | 2018-08-09 | Caris Science, Inc. | Targeted oligonucleotides |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
| US7462452B2 (en) * | 2004-04-30 | 2008-12-09 | Pacific Biosciences Of California, Inc. | Field-switch sequencing |
| US9035035B2 (en) * | 2004-11-05 | 2015-05-19 | Genovoxx Gmbh | Macromolecular nucleotide compounds and methods for using the same |
| WO2009073201A2 (en) * | 2007-12-04 | 2009-06-11 | Pacific Biosciences Of California, Inc. | Alternate labeling strategies for single molecule sequencing |
| US9777320B2 (en) * | 2010-08-25 | 2017-10-03 | Pacific Biosciences Of California, Inc. | Molecular adaptors for dye conjugates |
| WO2012150035A1 (de) * | 2011-05-04 | 2012-11-08 | Genovoxx Gmbh | Nukleosid-triphosphat-konjugate und methoden zu deren anwendung |
| US9062091B2 (en) * | 2012-02-15 | 2015-06-23 | Pacific Biosciences Of California, Inc. | Polymerase enzyme substrates with protein shield |
-
2020
- 2020-05-22 IL IL316901A patent/IL316901A/en unknown
- 2020-05-22 WO PCT/US2020/034409 patent/WO2020243017A1/en not_active Ceased
- 2020-05-22 KR KR1020237040302A patent/KR102823471B1/ko active Active
- 2020-05-22 KR KR1020217037728A patent/KR102607124B1/ko active Active
- 2020-05-22 CA CA3137120A patent/CA3137120A1/en active Pending
- 2020-05-22 EP EP20815612.5A patent/EP3947731A4/en active Pending
- 2020-05-22 CN CN202080042516.6A patent/CN113939601A/zh active Pending
- 2020-05-22 IL IL301380A patent/IL301380B2/en unknown
- 2020-05-22 AU AU2020285657A patent/AU2020285657B2/en active Active
- 2020-05-22 JP JP2021561845A patent/JP7542000B2/ja active Active
- 2020-05-22 SG SG11202112049VA patent/SG11202112049VA/en unknown
- 2020-05-22 GB GB2115667.4A patent/GB2597398B/en active Active
- 2020-05-22 KR KR1020257019970A patent/KR20250096873A/ko active Pending
- 2020-05-22 DE DE112020002516.0T patent/DE112020002516B4/de active Active
-
2021
- 2021-10-24 IL IL287528A patent/IL287528B2/en unknown
-
2022
- 2022-12-22 AU AU2022291540A patent/AU2022291540B2/en active Active
-
2024
- 2024-08-16 JP JP2024137063A patent/JP2024174880A/ja active Pending
-
2025
- 2025-01-20 AU AU2025200380A patent/AU2025200380A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050158761A1 (en) | 1999-05-19 | 2005-07-21 | Jonas Korlach | Method for sequencing nucleic acid molecules |
| WO2018137826A1 (en) | 2017-01-26 | 2018-08-02 | Qiagen Gmbh | Method for enriching template nucleic acids |
| WO2018144854A1 (en) | 2017-02-02 | 2018-08-09 | Caris Science, Inc. | Targeted oligonucleotides |
Non-Patent Citations (2)
| Title |
|---|
| J Am Chem Soc, 133(49): 19878-19888 (2011.11.18.) |
| Proc Natl Acad Sci USA, 103(52): 19635-19640 (2006.12.14.) |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2597398B (en) | 2024-03-06 |
| KR20250096873A (ko) | 2025-06-27 |
| JP7542000B2 (ja) | 2024-08-29 |
| AU2022291540B2 (en) | 2024-11-14 |
| IL301380B1 (en) | 2025-01-01 |
| IL287528B1 (en) | 2023-04-01 |
| IL316901A (en) | 2025-01-01 |
| SG11202112049VA (en) | 2021-12-30 |
| IL301380A (en) | 2023-05-01 |
| DE112020002516T5 (de) | 2022-03-24 |
| CA3137120A1 (en) | 2020-12-03 |
| EP3947731A4 (en) | 2022-06-29 |
| CN113939601A (zh) | 2022-01-14 |
| JP2022535187A (ja) | 2022-08-05 |
| IL301380B2 (en) | 2025-05-01 |
| IL287528B2 (en) | 2023-08-01 |
| IL287528A (en) | 2021-12-01 |
| DE112020002516B4 (de) | 2025-03-13 |
| EP3947731A1 (en) | 2022-02-09 |
| KR20230165871A (ko) | 2023-12-05 |
| AU2025200380A1 (en) | 2025-02-06 |
| GB202115667D0 (en) | 2021-12-15 |
| KR20210144929A (ko) | 2021-11-30 |
| AU2020285657A1 (en) | 2021-11-18 |
| WO2020243017A1 (en) | 2020-12-03 |
| KR102607124B1 (ko) | 2023-11-29 |
| AU2020285657B2 (en) | 2022-10-06 |
| AU2022291540A1 (en) | 2023-02-02 |
| JP2024174880A (ja) | 2024-12-17 |
| GB2597398A (en) | 2022-01-26 |
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Legal Events
| Date | Code | Title | Description |
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| A107 | Divisional application of patent | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20231122 Application number text: 1020217037728 Filing date: 20211118 |
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| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20240821 Patent event code: PE09021S01D |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20250425 |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 20250617 Patent event code: PR07011E01D |
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| PR1002 | Payment of registration fee |
Payment date: 20250617 End annual number: 3 Start annual number: 1 |
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| PG1601 | Publication of registration |