JP7542000B2 - 核酸分析用の多価性結合組成物 - Google Patents

核酸分析用の多価性結合組成物 Download PDF

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JP7542000B2
JP7542000B2 JP2021561845A JP2021561845A JP7542000B2 JP 7542000 B2 JP7542000 B2 JP 7542000B2 JP 2021561845 A JP2021561845 A JP 2021561845A JP 2021561845 A JP2021561845 A JP 2021561845A JP 7542000 B2 JP7542000 B2 JP 7542000B2
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nucleotide
nucleic acid
polymer
binding
target nucleic
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JP2022535187A (ja
JP2022535187A5 (https=
Inventor
アルスラーン，シナン
ホー，モリー
ケリンジャー，マシュー
ルヴィユ，ジェイク
プレヴァイト，マイケル
ジャオ，ジュンホア
ジャン，スー
ロペス，タイラー
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エレメント バイオサイエンシーズ，インク．
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Priority claimed from US16/579,794 external-priority patent/US10768173B1/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/10—Nucleotidyl transfering
    • C12Q2521/101—DNA polymerase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/157—A reaction step characterised by the number of molecules incorporated or released
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/149—Particles, e.g. beads

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2021561845A 2019-05-24 2020-05-22 核酸分析用の多価性結合組成物 Active JP7542000B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024137063A JP2024174880A (ja) 2019-05-24 2024-08-16 核酸分析用の多価性結合組成物

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962852876P 2019-05-24 2019-05-24
US62/852,876 2019-05-24
US201962897172P 2019-09-06 2019-09-06
US62/897,172 2019-09-06
US16/579,794 2019-09-23
US16/579,794 US10768173B1 (en) 2019-09-06 2019-09-23 Multivalent binding composition for nucleic acid analysis
PCT/US2020/034409 WO2020243017A1 (en) 2019-05-24 2020-05-22 Multivalent binding composition for nucleic acid analysis

Related Child Applications (1)

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JP2024137063A Division JP2024174880A (ja) 2019-05-24 2024-08-16 核酸分析用の多価性結合組成物

Publications (3)

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JP2022535187A JP2022535187A (ja) 2022-08-05
JP2022535187A5 JP2022535187A5 (https=) 2023-03-17
JP7542000B2 true JP7542000B2 (ja) 2024-08-29

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JP2021561845A Active JP7542000B2 (ja) 2019-05-24 2020-05-22 核酸分析用の多価性結合組成物
JP2024137063A Pending JP2024174880A (ja) 2019-05-24 2024-08-16 核酸分析用の多価性結合組成物

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EP (1) EP3947731A4 (https=)
JP (2) JP7542000B2 (https=)
KR (3) KR102823471B1 (https=)
CN (1) CN113939601A (https=)
AU (3) AU2020285657B2 (https=)
CA (1) CA3137120A1 (https=)
DE (1) DE112020002516B4 (https=)
GB (1) GB2597398B (https=)
IL (3) IL316901A (https=)
SG (1) SG11202112049VA (https=)
WO (1) WO2020243017A1 (https=)

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WO2019241305A1 (en) 2018-06-12 2019-12-19 Element Biosciences, Inc. Improved reverse transcriptase for nucleic acid sequencing
US10768173B1 (en) 2019-09-06 2020-09-08 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
WO2020102766A2 (en) 2018-11-15 2020-05-22 Element Biosciences, Inc. Methods for generating circular nucleic acid molecules
AU2019392932B2 (en) 2018-12-07 2023-11-02 Element Biosciences, Inc. Flow cell device and use thereof
US12313627B2 (en) 2019-05-01 2025-05-27 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
US12391929B2 (en) 2019-05-24 2025-08-19 Element Biosciences, Inc. Polymerase-nucleotide conjugates for sequencing by trapping
US11287422B2 (en) 2019-09-23 2022-03-29 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
US11060138B1 (en) 2020-01-17 2021-07-13 Element Biosciences, Inc. Nucleic acid sequencing systems
US11198121B1 (en) 2020-06-10 2021-12-14 Element Biosciences, Inc. Flow cell systems and devices
GB2599729A (en) * 2020-10-12 2022-04-13 Sumitomo Chemical Co Method comprising light emitting marker
CA3196800A1 (en) 2020-10-30 2022-05-05 Element Biosciences, Inc. Reagents for massively parallel nucleic acid sequencing
AU2022316142A1 (en) 2021-07-21 2024-02-22 Element Biosciences, Inc. Optical systems for nucleic acid sequencing and methods thereof
KR20230153706A (ko) 2022-04-29 2023-11-07 연세대학교 산학협력단 핵산의 검출 또는 분리용 조성물 및 이를 이용한 핵산의 검출 또는 분리 방법
EP4573213A1 (en) 2022-08-15 2025-06-25 Element Biosciences, Inc. Spatially resolved surface capture of nucleic acids
CN116024315B (zh) * 2022-11-30 2025-09-09 温州医科大学 一种基于链置换反应的多价双锁钥系统及其在核苷酸多态性检测中的应用
WO2026080904A2 (en) 2024-10-11 2026-04-16 Element Biosciences, Inc. Systems and methods for performing dna sequencing

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US20090186343A1 (en) 2003-01-28 2009-07-23 Visigen Biotechnologies, Inc. Methods for preparing modified biomolecules, modified biomolecules and methods for using same

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US9035035B2 (en) * 2004-11-05 2015-05-19 Genovoxx Gmbh Macromolecular nucleotide compounds and methods for using the same
WO2009073201A2 (en) * 2007-12-04 2009-06-11 Pacific Biosciences Of California, Inc. Alternate labeling strategies for single molecule sequencing
US9777320B2 (en) * 2010-08-25 2017-10-03 Pacific Biosciences Of California, Inc. Molecular adaptors for dye conjugates
WO2012150035A1 (de) * 2011-05-04 2012-11-08 Genovoxx Gmbh Nukleosid-triphosphat-konjugate und methoden zu deren anwendung
US9062091B2 (en) * 2012-02-15 2015-06-23 Pacific Biosciences Of California, Inc. Polymerase enzyme substrates with protein shield
EP3589752B1 (en) 2017-01-26 2021-05-19 QIAGEN GmbH Method for generating a sequencing library
WO2018144854A1 (en) 2017-02-02 2018-08-09 Caris Science, Inc. Targeted oligonucleotides

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US20090186343A1 (en) 2003-01-28 2009-07-23 Visigen Biotechnologies, Inc. Methods for preparing modified biomolecules, modified biomolecules and methods for using same
WO2005111240A2 (en) 2004-04-30 2005-11-24 Li-Cor, Inc. Field-switch sequencing

Non-Patent Citations (2)

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Title
J.P.Anderson, et al.，NANO LETTERS，2013年，Vol.10，p.788-792
Technology Spotligh: Illumina(R) Sequencing ［オンライン］，2010年，［検索日 2024.2.22］, インターネット：<URL: https://www.illumina.com/documents/products/techspotlights/techspotlight_sequencing.pdf>

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Publication number Publication date
GB2597398B (en) 2024-03-06
KR20250096873A (ko) 2025-06-27
AU2022291540B2 (en) 2024-11-14
IL301380B1 (en) 2025-01-01
IL287528B1 (en) 2023-04-01
IL316901A (en) 2025-01-01
SG11202112049VA (en) 2021-12-30
IL301380A (en) 2023-05-01
DE112020002516T5 (de) 2022-03-24
CA3137120A1 (en) 2020-12-03
EP3947731A4 (en) 2022-06-29
CN113939601A (zh) 2022-01-14
JP2022535187A (ja) 2022-08-05
IL301380B2 (en) 2025-05-01
IL287528B2 (en) 2023-08-01
IL287528A (en) 2021-12-01
DE112020002516B4 (de) 2025-03-13
EP3947731A1 (en) 2022-02-09
KR20230165871A (ko) 2023-12-05
AU2025200380A1 (en) 2025-02-06
GB202115667D0 (en) 2021-12-15
KR102823471B1 (ko) 2025-06-19
KR20210144929A (ko) 2021-11-30
AU2020285657A1 (en) 2021-11-18
WO2020243017A1 (en) 2020-12-03
KR102607124B1 (ko) 2023-11-29
AU2020285657B2 (en) 2022-10-06
AU2022291540A1 (en) 2023-02-02
JP2024174880A (ja) 2024-12-17
GB2597398A (en) 2022-01-26

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