GB2279251A - High dose pharmaceutical compositions - Google Patents

High dose pharmaceutical compositions Download PDF

Info

Publication number
GB2279251A
GB2279251A GB9410987A GB9410987A GB2279251A GB 2279251 A GB2279251 A GB 2279251A GB 9410987 A GB9410987 A GB 9410987A GB 9410987 A GB9410987 A GB 9410987A GB 2279251 A GB2279251 A GB 2279251A
Authority
GB
United Kingdom
Prior art keywords
ibuprofen
treatment
salt
pharmaceutical composition
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9410987A
Other languages
English (en)
Other versions
GB9410987D0 (en
Inventor
Federico Stroppolo
Daniele Bonadeo
Gian Franco Fornasini
Annibale Gazzaniga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Publication of GB9410987D0 publication Critical patent/GB9410987D0/en
Publication of GB2279251A publication Critical patent/GB2279251A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB9410987A 1993-06-21 1994-05-31 High dose pharmaceutical compositions Withdrawn GB2279251A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001324A IT1264855B1 (it) 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici

Publications (2)

Publication Number Publication Date
GB9410987D0 GB9410987D0 (en) 1994-07-20
GB2279251A true GB2279251A (en) 1995-01-04

Family

ID=11366435

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9410987A Withdrawn GB2279251A (en) 1993-06-21 1994-05-31 High dose pharmaceutical compositions

Country Status (12)

Country Link
US (1) US5510385A (https=)
JP (1) JPH0710749A (https=)
BE (1) BE1007193A5 (https=)
CA (1) CA2125644C (https=)
CH (1) CH686866A5 (https=)
DE (1) DE4420858A1 (https=)
ES (1) ES2099022B1 (https=)
FR (1) FR2706891B1 (https=)
GB (1) GB2279251A (https=)
IT (1) IT1264855B1 (https=)
NL (1) NL9401006A (https=)
SE (1) SE9402156L (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146149A (zh) * 1994-02-24 1997-03-26 株式会社大塚制药工场 增强止痛效果的制剂
NZ333474A (en) 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US6251426B1 (en) 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6344479B1 (en) 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
NZ532096A (en) * 2001-09-28 2006-10-27 Mcneil Ppc Inc Dosage forms having an inner core and outer shell with different shapes
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
CN1758904A (zh) 2003-03-21 2006-04-12 麦克内尔-Ppc股份有限公司 非甾体抗炎药物的给药方案
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
MXPA06014185A (es) * 2004-06-07 2007-04-16 Strides Arcolab Ltd Composicion farmaceutica que contiene una solucion estable y clara de medicamento anti-inflmatorio en capsulas de gelatina blanda, y proceso para producirlo.
US20050281876A1 (en) 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20080075767A1 (en) * 2006-06-30 2008-03-27 Jin Xiao P Ibuprofen-containing liquid filled hard capsules
KR20090088913A (ko) 2006-11-21 2009-08-20 맥네일-피피씨, 인코포레이티드 개질된 방출형 진통 현탁제
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
CA2696063C (en) 2007-08-15 2014-05-06 Mcneil-Ppc, Inc. Immediate release and sustained release ibuprofen dosing form
US8143314B1 (en) * 2007-09-13 2012-03-27 Robert Carl Stover Methods and formulations for treating ineffective or decreased esophageal motility
CN101390844B (zh) * 2007-09-23 2011-11-09 天津医科大学 精氨酸布洛芬片剂及其制备方法
CN101265178A (zh) * 2008-04-25 2008-09-17 北京阜康仁生物制药科技有限公司 一种右旋布洛芬的氨基酸盐及其药用组合物
BR122021011394B1 (pt) * 2008-12-04 2021-09-28 Chongxi Yu Composição de alta penetração de um fármaco principal, e uso de uma hpc
JP5977672B2 (ja) * 2009-04-27 2016-08-24 ラボラトリオ デ アプリカシオネス ファルマコディナミカス，エセ．アー．Ｌａｂｏｒａｔｏｒｉｏ Ｄｅ Ａｐｌｉｃａｃｉｏｎｅｓ Ｆａｒｍａｃｏｄｉｎａｍｉｃａｓ，Ｓ．Ａ． イブプロフェンリシナートの経口投与用の懸濁液
CN101978955A (zh) * 2010-11-05 2011-02-23 航天中心医院 右旋布洛芬氨基酸盐片剂及其制备方法
RS53612B1 (sr) * 2011-11-17 2015-04-30 Zambon S.P.A. Čvrste farmaceutske kompozicije koje sadrže ibuprofen soli
BR112014019526B8 (pt) 2012-02-07 2022-08-30 Chenango Zero Llc Forma de dosagem de liberação rápida e seu método de produção
CA2884270A1 (en) 2012-09-18 2014-03-27 Mcneil-Ppc, Inc. Sustained release oral dosage forms comprising low melting propionic acid derivative particles
CA2884119A1 (en) 2012-09-18 2014-03-27 Mcneil-Ppc, Inc. Low melting propionic acid derivative particles for use in oral dosage forms
US10583089B2 (en) 2016-07-19 2020-03-10 Johnson & Johnson Consumer Inc. Tablets having discontinuous coated regions
CA3242369A1 (en) 2016-07-19 2018-01-25 Johnson & Johnson Consumer Inc. (A Delaware Corporation) Tablets having discontinuous coated regions
JP7116059B2 (ja) 2016-11-21 2022-08-09 ジャスト－エヴォテック バイオロジックス、インコーポレイテッド アフリベルセプト製剤及びその使用
MY202872A (en) 2017-11-20 2024-05-28 Just Evotec Biologics Inc Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof
US20190224129A1 (en) 2018-01-22 2019-07-25 Johnson & Johnson Consumer Inc. Perforated capsules
SI3996699T1 (sl) 2019-07-09 2023-10-30 Farmalider, S. A. Kombinacija ibuprofena in tramadola za lajšanje bolečine
US20210378968A1 (en) 2020-05-28 2021-12-09 Johnson & Johnson Consumer Inc. Multi-cavity customizable dosage forms

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
EP0424028A2 (en) * 1989-10-17 1991-04-24 Merck & Co. Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics
EP0505180A1 (en) * 1991-03-22 1992-09-23 Merck & Co. Inc. High-content ibuprofen lysinate pharmaceutical formulation
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
HUT59656A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424028A2 (en) * 1989-10-17 1991-04-24 Merck & Co. Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
EP0505180A1 (en) * 1991-03-22 1992-09-23 Merck & Co. Inc. High-content ibuprofen lysinate pharmaceutical formulation
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations

Also Published As

Publication number Publication date
IT1264855B1 (it) 1996-10-17
ITMI931324A0 (it) 1993-06-18
CH686866A5 (it) 1996-07-31
SE9402156L (sv) 1994-12-22
FR2706891A1 (https=) 1994-12-30
BE1007193A5 (fr) 1995-04-18
FR2706891B1 (https=) 1995-10-20
DE4420858A1 (de) 1994-12-22
CA2125644C (en) 2007-06-05
ITMI931324A1 (it) 1994-12-21
ES2099022B1 (es) 1998-01-16
CA2125644A1 (en) 1994-12-22
ES2099022A1 (es) 1997-05-01
US5510385A (en) 1996-04-23
JPH0710749A (ja) 1995-01-13
SE9402156D0 (sv) 1994-06-20
GB9410987D0 (en) 1994-07-20
NL9401006A (nl) 1995-01-16

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)