JPH0710749A - S(+)−2−(4−イソブチルフェニル)プロピオン酸と塩基性アミノ酸との塩を含有する医薬組成物 - Google Patents

S(+)−2−(4−イソブチルフェニル)プロピオン酸と塩基性アミノ酸との塩を含有する医薬組成物

Info

Publication number
JPH0710749A
JPH0710749A JP6136833A JP13683394A JPH0710749A JP H0710749 A JPH0710749 A JP H0710749A JP 6136833 A JP6136833 A JP 6136833A JP 13683394 A JP13683394 A JP 13683394A JP H0710749 A JPH0710749 A JP H0710749A
Authority
JP
Japan
Prior art keywords
ibuprofen
pharmaceutical composition
salt
oral administration
alginate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6136833A
Other languages
English (en)
Japanese (ja)
Inventor
Stroppolo Federico
ストロッポロ フェデリコ
Bonadeo Daniele
ボナデオ ダニエレ
Gian F Fornasini
フランコ フォルナッシニ ジァン
Gazzaniga Annibale
ギャザニーガ アンニバーレ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Publication of JPH0710749A publication Critical patent/JPH0710749A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP6136833A 1993-06-21 1994-06-20 S(+)−2−(4−イソブチルフェニル)プロピオン酸と塩基性アミノ酸との塩を含有する医薬組成物 Pending JPH0710749A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93A001324 1993-06-21
IT93MI001324A IT1264855B1 (it) 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici

Publications (1)

Publication Number Publication Date
JPH0710749A true JPH0710749A (ja) 1995-01-13

Family

ID=11366435

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6136833A Pending JPH0710749A (ja) 1993-06-21 1994-06-20 S(+)−2−(4−イソブチルフェニル)プロピオン酸と塩基性アミノ酸との塩を含有する医薬組成物

Country Status (12)

Country Link
US (1) US5510385A (https=)
JP (1) JPH0710749A (https=)
BE (1) BE1007193A5 (https=)
CA (1) CA2125644C (https=)
CH (1) CH686866A5 (https=)
DE (1) DE4420858A1 (https=)
ES (1) ES2099022B1 (https=)
FR (1) FR2706891B1 (https=)
GB (1) GB2279251A (https=)
IT (1) IT1264855B1 (https=)
NL (1) NL9401006A (https=)
SE (1) SE9402156L (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012525359A (ja) * 2009-04-27 2012-10-22 ラボラトリオ デ アプリカシオネス ファルマコディナミカス,エセ.アー. イブプロフェンリシナートの経口投与用の懸濁液

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767091A (en) * 1994-02-24 1998-06-16 Otsuka Pharmaceutical Factory, Inc. Analgesic effect enhancing preparations
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US6251426B1 (en) 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6344479B1 (en) 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
CA2461616A1 (en) * 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
WO2004093864A1 (en) 2003-03-21 2004-11-04 Mcneil-Ppc, Inc. Non-steroidal anti-inflammatory drug dosing regimen
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
CA2570649A1 (en) * 2004-06-07 2005-12-22 Strides Arcolab Limited Pharmaceutical composition containing a stable and clear solution of anti-inflammatory drug in soft gelatin capsule and process for producing the same
US20050281876A1 (en) * 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
MX2009000145A (es) * 2006-06-30 2009-01-23 Mcneil Ppc Inc Capsulas duras llenas con liquido que contiene ibuprofeno.
JP2010510320A (ja) 2006-11-21 2010-04-02 マクニール−ピーピーシー・インコーポレーテツド 改変型放出鎮痛性懸濁液
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
CA2696063C (en) * 2007-08-15 2014-05-06 Mcneil-Ppc, Inc. Immediate release and sustained release ibuprofen dosing form
US8143314B1 (en) * 2007-09-13 2012-03-27 Robert Carl Stover Methods and formulations for treating ineffective or decreased esophageal motility
CN101390844B (zh) * 2007-09-23 2011-11-09 天津医科大学 精氨酸布洛芬片剂及其制备方法
CN101265178A (zh) * 2008-04-25 2008-09-17 北京阜康仁生物制药科技有限公司 一种右旋布洛芬的氨基酸盐及其药用组合物
WO2010065936A1 (en) * 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
CN101978955A (zh) * 2010-11-05 2011-02-23 航天中心医院 右旋布洛芬氨基酸盐片剂及其制备方法
ES2519592T3 (es) * 2011-11-17 2014-11-07 Zambon S.P.A. Composiciones sólidas farmacéuticas que contienen sales de ibuprofeno
MX359529B (es) 2012-02-07 2018-10-01 Mcneil Ppc Inc Tabletas recubiertas de desintegración rápida.
BR112015005968A2 (pt) 2012-09-18 2017-07-04 Mcneil Ppc Inc formas de dosagem orais de liberação prolongada compreendendo partículas derivadas do ácido propiônico com baixo ponto de fusão
BR112015005876A2 (pt) 2012-09-18 2017-07-04 Mcneil Ppc Inc partículas derivadas de ácido propiônico com baixo ponto de fusão para uso em formas de dosagem oral
US10583089B2 (en) 2016-07-19 2020-03-10 Johnson & Johnson Consumer Inc. Tablets having discontinuous coated regions
CN109689030A (zh) 2016-07-19 2019-04-26 强生消费者公司 具有不连续涂覆区域的片剂
CN109937034B (zh) 2016-11-21 2022-09-16 济世-伊沃泰克生物制品有限公司 阿柏西普制剂及其用途
CA3081094A1 (en) 2017-11-20 2019-05-23 Alison J. GILLESPIE Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof
RU2020127753A (ru) 2018-01-22 2022-02-24 Джонсон энд Джонсон Консьюмер Инк. Перфорированные капсулы
SI3996699T1 (sl) 2019-07-09 2023-10-30 Farmalider, S. A. Kombinacija ibuprofena in tramadola za lajšanje bolečine
US20210378968A1 (en) 2020-05-28 2021-12-09 Johnson & Johnson Consumer Inc. Multi-cavity customizable dosage forms

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
DK0424028T3 (da) * 1989-10-17 1996-01-29 Merck & Co Inc S(+)-ibuprofen-L-aminosyre og S(+)-ibuprofen-D-aminosyre som et forbedret smertestillende middel med fremskyndet indtrædelse
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
HUT59656A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components
ES2093192T3 (es) * 1991-03-22 1996-12-16 Merck & Co Inc Formulacion farmaceutica con elevado contenido de lisinato de ibuprofeno.
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012525359A (ja) * 2009-04-27 2012-10-22 ラボラトリオ デ アプリカシオネス ファルマコディナミカス,エセ.アー. イブプロフェンリシナートの経口投与用の懸濁液

Also Published As

Publication number Publication date
US5510385A (en) 1996-04-23
ES2099022A1 (es) 1997-05-01
DE4420858A1 (de) 1994-12-22
ITMI931324A1 (it) 1994-12-21
SE9402156L (sv) 1994-12-22
ITMI931324A0 (it) 1993-06-18
CA2125644A1 (en) 1994-12-22
GB2279251A (en) 1995-01-04
ES2099022B1 (es) 1998-01-16
FR2706891B1 (https=) 1995-10-20
CA2125644C (en) 2007-06-05
GB9410987D0 (en) 1994-07-20
FR2706891A1 (https=) 1994-12-30
SE9402156D0 (sv) 1994-06-20
NL9401006A (nl) 1995-01-16
IT1264855B1 (it) 1996-10-17
BE1007193A5 (fr) 1995-04-18
CH686866A5 (it) 1996-07-31

Similar Documents

Publication Publication Date Title
JPH0710749A (ja) S(+)−2−(4−イソブチルフェニル)プロピオン酸と塩基性アミノ酸との塩を含有する医薬組成物
US4689218A (en) Effervescent composition with analgesic activity
RU2128160C1 (ru) Трометаминная соль (+)-(s)-2-(3-бензоилфенил)пропионовой кислоты, способ ее получения, фармацевтическая композиция
CA2382886C (en) Benzamide formulation with histone deacetylase inhibitor activity
JP6027722B2 (ja) 脳梗塞の予防及び治療用医薬品の製造におけるl−ブチルフタリドの使用
US5525631A (en) Compositions of the ethyl ester of L-DOPA
KR19980064024A (ko) 약학 조성물
EP0710108B1 (en) Liquid pharmaceutical composition for oral use containing 2-(4-isobutylphenyl)propionic acid
JPS63146815A (ja) イブプロフェン含有医薬組成物
CZ281717B6 (cs) Terapeutické činidlo
FR2602141A1 (fr) Composition pharmaceutique a activite analgesique contenant de l'ibuprofene comme principe actif
US20050171203A1 (en) Pregabalin composition
BE1007194A3 (fr) Composition pharmaceutique ayant une activite analgesique.
NL9400481A (nl) Farmaceutische samenstelling die analgetische activiteit bezit.
WO1991006295A1 (en) Analgesic composition containing optically pure s(+) flurbiprofen
KR970011456B1 (ko) d-2-(6-메톡시-2-나프틸)-프로피온산의 광학활성 유도체와 이것을 함유한 약제학적 조성물
EP0935964A1 (en) Pharmaceutical compositions containing NSAIDs and piperine
US5185157A (en) Treatment of refractory Eosinophilia-Myalgia Syndrome with L-tryptophan composition
JP5782299B2 (ja) 神経因性疼痛用鎮痛剤
WO2016111310A1 (ja) 新規アンジオテンシン変換酵素阻害剤

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20040803

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20041028

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20041102

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050128

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20050531