GB2084573B - Improvements in or relating to 3-aryl-5-isothiazole derivatives - Google Patents
Improvements in or relating to 3-aryl-5-isothiazole derivativesInfo
- Publication number
- GB2084573B GB2084573B GB8128465A GB8128465A GB2084573B GB 2084573 B GB2084573 B GB 2084573B GB 8128465 A GB8128465 A GB 8128465A GB 8128465 A GB8128465 A GB 8128465A GB 2084573 B GB2084573 B GB 2084573B
- Authority
- GB
- United Kingdom
- Prior art keywords
- aryl
- relating
- isothiazole derivatives
- isothiazole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/189,435 US4346094A (en) | 1980-09-22 | 1980-09-22 | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2084573A GB2084573A (en) | 1982-04-15 |
| GB2084573B true GB2084573B (en) | 1984-09-12 |
Family
ID=22697314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8128465A Expired GB2084573B (en) | 1980-09-22 | 1981-09-21 | Improvements in or relating to 3-aryl-5-isothiazole derivatives |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4346094A (cs) |
| EP (1) | EP0048615B1 (cs) |
| JP (1) | JPS5785379A (cs) |
| KR (1) | KR830007597A (cs) |
| AR (1) | AR229103A1 (cs) |
| AT (1) | ATE7657T1 (cs) |
| AU (1) | AU7551681A (cs) |
| CS (1) | CS228536B2 (cs) |
| DD (1) | DD201790A5 (cs) |
| DE (1) | DE3163900D1 (cs) |
| DK (1) | DK417981A (cs) |
| ES (1) | ES505678A0 (cs) |
| FI (1) | FI812940L (cs) |
| GB (1) | GB2084573B (cs) |
| GR (1) | GR75046B (cs) |
| IL (1) | IL63890A0 (cs) |
| NO (1) | NO813208L (cs) |
| PL (1) | PL130497B1 (cs) |
| PT (1) | PT73711B (cs) |
| RO (1) | RO82216A (cs) |
| YU (1) | YU227181A (cs) |
| ZA (1) | ZA816549B (cs) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4428956A (en) | 1980-12-29 | 1984-01-31 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4431652A (en) * | 1980-12-29 | 1984-02-14 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4539328A (en) * | 1983-03-25 | 1985-09-03 | Fmc Corporation | Nematicidal isothiazole derivatives |
| US4620865A (en) * | 1983-11-07 | 1986-11-04 | Eli Lilly And Company | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides |
| IE59813B1 (en) * | 1986-05-09 | 1994-04-06 | Warner Lambert Co | Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them |
| ZW21687A1 (en) * | 1986-12-12 | 1988-07-20 | Hoffmann La Roche | Triazine derivatives |
| HU218942B (hu) * | 1990-11-30 | 2001-01-29 | Teijin Ltd. | 2-Fenil-tiazol-származékok, az ezeket tartalmazó gyógyászati készítmények, valamint eljárás a vegyületek előállítására |
| US5294630A (en) * | 1992-07-07 | 1994-03-15 | Eli Lilly And Company | Treatment of inflammatory bowel disease |
| US5436258A (en) * | 1992-09-09 | 1995-07-25 | Eli Lilly And Company | Prevention of bone resorption |
| MY117352A (en) * | 1995-10-31 | 2004-06-30 | Ciba Sc Holding Ag | Oximesulfonic acid esters and the use thereof as latent sulfonic acids. |
| ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
| EP1044002A4 (en) | 1997-11-07 | 2003-05-02 | Univ Johns Hopkins | METHODS FOR THE TREATMENT OF HEART CONTRACTILITY |
| TW575792B (en) * | 1998-08-19 | 2004-02-11 | Ciba Sc Holding Ag | New unsaturated oxime derivatives and the use thereof as latent acids |
| SG78412A1 (en) | 1999-03-31 | 2001-02-20 | Ciba Sc Holding Ag | Oxime derivatives and the use thereof as latent acids |
| KR20040089607A (ko) | 2002-02-06 | 2004-10-21 | 시바 스페셜티 케미칼스 홀딩 인크. | 설포네이트 유도체 및 잠산으로서의 이의 용도 |
| ATE440820T1 (de) * | 2004-08-27 | 2009-09-15 | Astellas Pharma Inc | 2-phenylpyridinderivat |
| US7612108B2 (en) * | 2004-08-27 | 2009-11-03 | Astellas Pharma Inc. | 2-phenylthiophene derivative |
| RU2008118156A (ru) | 2005-10-07 | 2009-11-20 | Астеллас Фарма Инк. (Jp) | Производное триарилкарбоновой кислоты |
| WO2007097403A1 (ja) | 2006-02-24 | 2007-08-30 | Astellas Pharma Inc. | 消化管潰瘍治療又は予防薬 |
| GB2450975B (en) | 2007-07-12 | 2010-02-24 | Ciba Holding Inc | Yellow radiation curing inks |
| MX2011008348A (es) | 2009-02-27 | 2011-09-01 | Teijin Pharma Ltd | Proceso para producir derivado heterociclico sustituido con fenilo a traves de acoplamiento usando catalizador de metal de transicion. |
| JP2012522084A (ja) | 2009-03-30 | 2012-09-20 | ビーエーエスエフ ソシエタス・ヨーロピア | Ｕｖ線量インジケータフィルム |
| AU2011294204B2 (en) | 2010-08-27 | 2015-07-23 | Teijin Limited | Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using a palladium compound |
| US9310677B2 (en) | 2011-01-28 | 2016-04-12 | Basf | Polymerizable composition comprising an oxime sulfonate as thermal curing agent |
| MY176149A (en) * | 2013-03-29 | 2020-07-24 | Teijin Pharma Ltd | Pyrazole derivative |
| CN106604912A (zh) | 2014-08-29 | 2017-04-26 | 巴斯夫欧洲公司 | 肟磺酸酯衍生物 |
| WO2016174043A1 (de) | 2015-04-29 | 2016-11-03 | Bsn Medical Gmbh | Mehrstufiges verfahren zur no-herstellung |
| JP6812361B2 (ja) | 2015-04-29 | 2021-01-13 | ビーエスエヌ メディカル ゲーエムベーハー | 医療用入浴機器 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1178604A (en) * | 1966-03-21 | 1970-01-21 | American Cyanamid Co | Novel Pyridinium Salts and Methods for Preparing Same |
| US3464999A (en) * | 1967-07-27 | 1969-09-02 | R & L Molecular Research Ltd | Thiadiazolylisothiazoles |
| GB1180268A (en) * | 1967-09-26 | 1970-02-04 | Ici Ltd | Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives |
| GB1192701A (en) * | 1968-03-22 | 1970-05-20 | Ici Ltd | Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same |
| US3681498A (en) * | 1970-10-19 | 1972-08-01 | American Cyanamid Co | Isothiazolyl pyridinium salts as hypoglycemic agents |
-
1980
- 1980-09-22 US US06/189,435 patent/US4346094A/en not_active Expired - Lifetime
-
1981
- 1981-09-19 PL PL1981233103A patent/PL130497B1/pl unknown
- 1981-09-20 IL IL63890A patent/IL63890A0/xx unknown
- 1981-09-21 AT AT81304325T patent/ATE7657T1/de not_active IP Right Cessation
- 1981-09-21 FI FI812940A patent/FI812940L/fi not_active Application Discontinuation
- 1981-09-21 PT PT73711A patent/PT73711B/pt unknown
- 1981-09-21 GB GB8128465A patent/GB2084573B/en not_active Expired
- 1981-09-21 ES ES505678A patent/ES505678A0/es active Granted
- 1981-09-21 NO NO813208A patent/NO813208L/no unknown
- 1981-09-21 DK DK417981A patent/DK417981A/da not_active Application Discontinuation
- 1981-09-21 RO RO81105346A patent/RO82216A/ro unknown
- 1981-09-21 AU AU75516/81A patent/AU7551681A/en not_active Abandoned
- 1981-09-21 EP EP81304325A patent/EP0048615B1/en not_active Expired
- 1981-09-21 AR AR286818A patent/AR229103A1/es active
- 1981-09-21 YU YU02271/81A patent/YU227181A/xx unknown
- 1981-09-21 GR GR66108A patent/GR75046B/el unknown
- 1981-09-21 ZA ZA816549A patent/ZA816549B/xx unknown
- 1981-09-21 DE DE8181304325T patent/DE3163900D1/de not_active Expired
- 1981-09-22 CS CS816978A patent/CS228536B2/cs unknown
- 1981-09-22 DD DD81233487A patent/DD201790A5/de unknown
- 1981-09-22 JP JP56150483A patent/JPS5785379A/ja active Pending
- 1981-09-22 KR KR1019810003537A patent/KR830007597A/ko unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL233103A1 (cs) | 1982-12-20 |
| ES8301225A1 (es) | 1982-12-01 |
| RO82216B (ro) | 1983-06-30 |
| CS228536B2 (en) | 1984-05-14 |
| KR830007597A (ko) | 1983-11-04 |
| JPS5785379A (en) | 1982-05-28 |
| ATE7657T1 (de) | 1984-06-15 |
| YU227181A (en) | 1983-10-31 |
| ES505678A0 (es) | 1982-12-01 |
| GB2084573A (en) | 1982-04-15 |
| PT73711B (en) | 1982-12-20 |
| IL63890A0 (en) | 1981-12-31 |
| DE3163900D1 (en) | 1984-07-05 |
| GR75046B (cs) | 1984-07-12 |
| ZA816549B (en) | 1983-04-27 |
| EP0048615B1 (en) | 1984-05-30 |
| PL130497B1 (en) | 1984-08-31 |
| US4346094A (en) | 1982-08-24 |
| FI812940L (fi) | 1982-03-23 |
| EP0048615A1 (en) | 1982-03-31 |
| AR229103A1 (es) | 1983-06-15 |
| DD201790A5 (de) | 1983-08-10 |
| DK417981A (da) | 1982-03-23 |
| PT73711A (en) | 1981-10-01 |
| NO813208L (no) | 1982-03-23 |
| AU7551681A (en) | 1982-04-01 |
| RO82216A (ro) | 1983-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 7732 | Case decided by the comptroller ** patent revoked (sect. 73(2)/1977) |