GB201719881D0 - Solid forms of plasma kallikrein inhibitor and salts thereof - Google Patents

Solid forms of plasma kallikrein inhibitor and salts thereof

Info

Publication number
GB201719881D0
GB201719881D0 GBGB1719881.3A GB201719881A GB201719881D0 GB 201719881 D0 GB201719881 D0 GB 201719881D0 GB 201719881 A GB201719881 A GB 201719881A GB 201719881 D0 GB201719881 D0 GB 201719881D0
Authority
GB
United Kingdom
Prior art keywords
salts
solid forms
plasma kallikrein
kallikrein inhibitor
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1719881.3A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kalvista Pharmaceuticals Ltd
Original Assignee
Kalvista Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kalvista Pharmaceuticals Ltd filed Critical Kalvista Pharmaceuticals Ltd
Priority to GBGB1719881.3A priority Critical patent/GB201719881D0/en
Publication of GB201719881D0 publication Critical patent/GB201719881D0/en
Priority to RU2020121150A priority patent/RU2020121150A/ru
Priority to MX2020005422A priority patent/MX2020005422A/es
Priority to BR112020010064-1A priority patent/BR112020010064A2/pt
Priority to EP18815306.8A priority patent/EP3717469A1/en
Priority to KR1020207015220A priority patent/KR20200094142A/ko
Priority to CA3082304A priority patent/CA3082304A1/en
Priority to JP2020526923A priority patent/JP2021504310A/ja
Priority to PCT/GB2018/053466 priority patent/WO2019106377A1/en
Priority to CN201880077596.1A priority patent/CN111433197A/zh
Priority to AU2018374541A priority patent/AU2018374541B2/en
Priority to US16/767,717 priority patent/US11584735B2/en
Priority to IL274555A priority patent/IL274555A/en
Priority to US18/111,219 priority patent/US20230203012A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB1719881.3A 2017-11-29 2017-11-29 Solid forms of plasma kallikrein inhibitor and salts thereof Ceased GB201719881D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
GBGB1719881.3A GB201719881D0 (en) 2017-11-29 2017-11-29 Solid forms of plasma kallikrein inhibitor and salts thereof
US16/767,717 US11584735B2 (en) 2017-11-29 2018-11-29 Solid forms of a plasma kallikrein inhibitor and salts thereof
CA3082304A CA3082304A1 (en) 2017-11-29 2018-11-29 Solid forms of a plasma kallikrein inhibitor and salts thereof
PCT/GB2018/053466 WO2019106377A1 (en) 2017-11-29 2018-11-29 Solid forms of a plasma kallikrein inhibitor and salts thereof
BR112020010064-1A BR112020010064A2 (pt) 2017-11-29 2018-11-29 formas sólidas de um inibidor de calicreína e sais do mesmo
EP18815306.8A EP3717469A1 (en) 2017-11-29 2018-11-29 Solid forms of a plasma kallikrein inhibitor and salts thereof
KR1020207015220A KR20200094142A (ko) 2017-11-29 2018-11-29 혈장 칼리크레인 저해제 및 그 염의 고체 형태
RU2020121150A RU2020121150A (ru) 2017-11-29 2018-11-29 Твердые формы ингибитора калликреина плазмы и его солей
JP2020526923A JP2021504310A (ja) 2017-11-29 2018-11-29 血漿カリクレイン阻害剤及びその塩の固体形態
MX2020005422A MX2020005422A (es) 2017-11-29 2018-11-29 Formas solidas de un inhibidor de calicreina en plasma y sales del mismo.
CN201880077596.1A CN111433197A (zh) 2017-11-29 2018-11-29 血浆激肽释放酶抑制剂及其盐的固体形式
AU2018374541A AU2018374541B2 (en) 2017-11-29 2018-11-29 Solid forms of a plasma kallikrein inhibitor and salts thereof
IL274555A IL274555A (en) 2017-11-29 2020-05-10 Solid forms of the plasma inhibitor kallikrein and their salts
US18/111,219 US20230203012A1 (en) 2017-11-29 2023-02-17 Solid forms of a plasma kallikrein inhibitor and salts thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1719881.3A GB201719881D0 (en) 2017-11-29 2017-11-29 Solid forms of plasma kallikrein inhibitor and salts thereof

Publications (1)

Publication Number Publication Date
GB201719881D0 true GB201719881D0 (en) 2018-01-10

Family

ID=60950492

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1719881.3A Ceased GB201719881D0 (en) 2017-11-29 2017-11-29 Solid forms of plasma kallikrein inhibitor and salts thereof

Country Status (13)

Country Link
US (2) US11584735B2 (enExample)
EP (1) EP3717469A1 (enExample)
JP (1) JP2021504310A (enExample)
KR (1) KR20200094142A (enExample)
CN (1) CN111433197A (enExample)
AU (1) AU2018374541B2 (enExample)
BR (1) BR112020010064A2 (enExample)
CA (1) CA3082304A1 (enExample)
GB (1) GB201719881D0 (enExample)
IL (1) IL274555A (enExample)
MX (1) MX2020005422A (enExample)
RU (1) RU2020121150A (enExample)
WO (1) WO2019106377A1 (enExample)

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GB201609603D0 (en) * 2016-06-01 2016-07-13 Kalvista Pharmaceuticals Ltd Polymorphs of N-[(6-cyano-2-fluoro-3-methoxyphenyl)Methyl]-3-(methoxymethyl)-1-({4-[(2-ox opyridin-1-YL)Methyl]phenyl}methyl)pyrazole-4-carboxamide
GB201719881D0 (en) 2017-11-29 2018-01-10 Kalvista Pharmaceuticals Ltd Solid forms of plasma kallikrein inhibitor and salts thereof
LT3716952T (lt) 2017-11-29 2022-04-11 Kalvista Pharmaceuticals Limited Vaisto formos, apimančios plazmos kalikreino inhibitorių
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CN114867477B (zh) * 2019-07-08 2024-12-27 雷佐鲁特公司 血浆激肽释放酶抑制剂的晶型
CN114206852A (zh) 2019-08-09 2022-03-18 卡尔维斯塔制药有限公司 血浆激肽释放酶抑制剂
ES2987744T3 (es) 2019-09-18 2024-11-18 Takeda Pharmaceuticals Co Inhibidores de calicreína plasmática y usos de los mismos
CN114667289B (zh) 2019-09-18 2025-08-26 武田药品工业有限公司 杂芳基血浆激肽释放酶抑制剂
TW202228686A (zh) 2020-10-15 2022-08-01 英商卡爾維斯塔製藥有限公司 血管性水腫之治療
JP2024505596A (ja) 2021-02-09 2024-02-06 カルビスタ・ファーマシューティカルズ・リミテッド 遺伝性血管性浮腫の治療
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