GB201513743D0 - Muscarinic agonists - Google Patents

Muscarinic agonists

Info

Publication number
GB201513743D0
GB201513743D0 GBGB1513743.3A GB201513743A GB201513743D0 GB 201513743 D0 GB201513743 D0 GB 201513743D0 GB 201513743 A GB201513743 A GB 201513743A GB 201513743 D0 GB201513743 D0 GB 201513743D0
Authority
GB
United Kingdom
Prior art keywords
muscarinic agonists
muscarinic
agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1513743.3A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nxera Pharma UK Ltd
Original Assignee
Heptares Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heptares Therapeutics Ltd filed Critical Heptares Therapeutics Ltd
Priority to GBGB1513743.3A priority Critical patent/GB201513743D0/en
Publication of GB201513743D0 publication Critical patent/GB201513743D0/en
Priority to PCT/GB2016/052385 priority patent/WO2017021729A1/en
Priority to EP16750222.8A priority patent/EP3331529B1/en
Priority to AU2016304387A priority patent/AU2016304387B2/en
Priority to DK16750222.8T priority patent/DK3331529T3/da
Priority to CA2994203A priority patent/CA2994203C/en
Priority to JP2018504992A priority patent/JP6843114B2/ja
Priority to US15/749,957 priority patent/US10738029B2/en
Priority to HK18109572.7A priority patent/HK1250138B/en
Priority to CN201680045224.1A priority patent/CN108025004B/zh
Priority to ES16750222T priority patent/ES2894637T3/es
Priority to US16/942,167 priority patent/US11254656B2/en
Priority to US17/672,302 priority patent/US12024499B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB1513743.3A 2015-08-03 2015-08-03 Muscarinic agonists Ceased GB201513743D0 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
GBGB1513743.3A GB201513743D0 (en) 2015-08-03 2015-08-03 Muscarinic agonists
ES16750222T ES2894637T3 (es) 2015-08-03 2016-08-03 Agonistas muscarínicos
JP2018504992A JP6843114B2 (ja) 2015-08-03 2016-08-03 ムスカリン作動薬
EP16750222.8A EP3331529B1 (en) 2015-08-03 2016-08-03 Muscarinic agonists
AU2016304387A AU2016304387B2 (en) 2015-08-03 2016-08-03 Muscarinic agonists
DK16750222.8T DK3331529T3 (da) 2015-08-03 2016-08-03 Muskarinagonister
CA2994203A CA2994203C (en) 2015-08-03 2016-08-03 Azaspiro compounds as muscarinic agonists
PCT/GB2016/052385 WO2017021729A1 (en) 2015-08-03 2016-08-03 Muscarinic agonists
US15/749,957 US10738029B2 (en) 2015-08-03 2016-08-03 Muscarinic agonists
HK18109572.7A HK1250138B (en) 2015-08-03 2016-08-03 Muscarinic agonists
CN201680045224.1A CN108025004B (zh) 2015-08-03 2016-08-03 毒蕈碱激动剂
US16/942,167 US11254656B2 (en) 2015-08-03 2020-07-29 Muscarinic agonists
US17/672,302 US12024499B2 (en) 2015-08-03 2022-02-15 Muscarinic agonists

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1513743.3A GB201513743D0 (en) 2015-08-03 2015-08-03 Muscarinic agonists

Publications (1)

Publication Number Publication Date
GB201513743D0 true GB201513743D0 (en) 2015-09-16

Family

ID=54063149

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1513743.3A Ceased GB201513743D0 (en) 2015-08-03 2015-08-03 Muscarinic agonists

Country Status (10)

Country Link
US (3) US10738029B2 (enExample)
EP (1) EP3331529B1 (enExample)
JP (1) JP6843114B2 (enExample)
CN (1) CN108025004B (enExample)
AU (1) AU2016304387B2 (enExample)
CA (1) CA2994203C (enExample)
DK (1) DK3331529T3 (enExample)
ES (1) ES2894637T3 (enExample)
GB (1) GB201513743D0 (enExample)
WO (1) WO2017021729A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106831541B (zh) 2011-11-18 2019-09-06 赫普泰雅治疗有限公司 毒蕈碱性m1受体激动剂
GB201404922D0 (en) 2014-03-19 2014-04-30 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201513740D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonist
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
GB201709652D0 (en) * 2017-06-16 2017-08-02 Heptares Therapeutics Ltd Pharmaceutical compounds
US11149022B2 (en) 2017-10-17 2021-10-19 Vanderbilt University Antagonists of the muscarinic acetylcholine receptor M4
CA3094366A1 (en) * 2018-03-23 2019-09-26 Pfizer Inc. Piperazine azaspiro derivatives
GB201810245D0 (en) * 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819961D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds
KR102798432B1 (ko) * 2019-10-09 2025-04-22 노파르티스 아게 M4 작용제로서의 5-옥사-2-아자스피로[3.4]옥탄 유도체
UY38906A (es) * 2019-10-09 2021-05-31 Novartis Ag Compuestos 2- derivados de azaspiro[3,4]octano como agonistas de m4 y composiciones de los mismos

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GB201504675D0 (en) * 2015-03-19 2015-05-06 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201513742D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
GB201513740D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonist
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
US10259787B2 (en) 2016-10-14 2019-04-16 Heptares Therapeutics Limited Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists
GB201709652D0 (en) 2017-06-16 2017-08-02 Heptares Therapeutics Ltd Pharmaceutical compounds
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GB201810239D0 (en) * 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201810245D0 (en) * 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819961D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202103211D0 (en) 2021-03-08 2021-04-21 Heptares Therapeutics Ltd Pharmaceutical compounds for use in therapy

Also Published As

Publication number Publication date
US12024499B2 (en) 2024-07-02
WO2017021729A1 (en) 2017-02-09
EP3331529A1 (en) 2018-06-13
HK1250138A1 (en) 2018-11-30
ES2894637T3 (es) 2022-02-15
US11254656B2 (en) 2022-02-22
US20200354339A1 (en) 2020-11-12
CA2994203A1 (en) 2017-02-09
CN108025004A (zh) 2018-05-11
JP6843114B2 (ja) 2021-03-17
US10738029B2 (en) 2020-08-11
AU2016304387A1 (en) 2018-02-22
JP2018522033A (ja) 2018-08-09
CA2994203C (en) 2023-11-28
CN108025004B (zh) 2021-07-09
EP3331529B1 (en) 2021-09-29
DK3331529T3 (da) 2021-10-18
US20230002354A1 (en) 2023-01-05
AU2016304387B2 (en) 2020-10-22
US20180222885A1 (en) 2018-08-09

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