AU2307999A - Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions - Google Patents

Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions

Info

Publication number
AU2307999A
AU2307999A AU23079/99A AU2307999A AU2307999A AU 2307999 A AU2307999 A AU 2307999A AU 23079/99 A AU23079/99 A AU 23079/99A AU 2307999 A AU2307999 A AU 2307999A AU 2307999 A AU2307999 A AU 2307999A
Authority
AU
Australia
Prior art keywords
myopia
conditions
various
treat glaucoma
muscarinic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU23079/99A
Inventor
Hwang-Hsing Chen
Anura Dantanarayana
Thomas R. Dean
Zixia Feng
Mark R Hellberg
Andrew Hoffman
Abdelmoula Namil
Najam Sharif
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of AU2307999A publication Critical patent/AU2307999A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU23079/99A 1997-12-23 1998-12-22 Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions Abandoned AU2307999A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6876597P 1997-12-23 1997-12-23
US60068765 1997-12-23
PCT/US1998/027590 WO1999032481A1 (en) 1997-12-23 1998-12-22 Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions

Publications (1)

Publication Number Publication Date
AU2307999A true AU2307999A (en) 1999-07-12

Family

ID=22084565

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23079/99A Abandoned AU2307999A (en) 1997-12-23 1998-12-22 Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions

Country Status (2)

Country Link
AU (1) AU2307999A (en)
WO (1) WO1999032481A1 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200101939T2 (en) 1999-01-28 2002-05-21 Bristol-Myers Squibb Company Antidepressant heterocyclic compounds
KR20010008898A (en) * 1999-07-05 2001-02-05 우종일 Nucleotide monomer containing six-membered azasugar and antisense oligomers thereof
ES2223588T3 (en) * 1999-10-13 2005-03-01 Banyu Pharmaceutical Co., Ltd. IMIDAZOLIDINONA SUBSTITUTED DERIVATIVES.
SI1598339T1 (en) * 2001-04-18 2009-12-31 Euro Celtique Sa 1-(4-amino-cyclohexyl)-1,3-dihydro-2h-benzimidazole-2-one derivatives and related compounds as nociceptin analogs and orl1 ligands for the treatment of pain
US7164024B2 (en) 2001-04-20 2007-01-16 Banyu Pharmaceutical Co., Ltd. Benzimidazolone derivatives
WO2004089942A2 (en) * 2001-10-02 2004-10-21 Acadia Pharmaceuticals Inc. Benzimidazolidinone derivatives as muscarinic agents
RU2288919C2 (en) 2001-10-02 2006-12-10 Акадиа Фармасьютикалз, Инк. Derivatives of benzimidazolidinone as agents for muscarinic receptors
US6951849B2 (en) 2001-10-02 2005-10-04 Acadia Pharmaceuticals Inc. Benzimidazolidinone derivatives as muscarinic agents
WO2003105781A2 (en) 2002-06-17 2003-12-24 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
DE602006019119D1 (en) * 2005-09-30 2011-02-03 Glaxo Group Ltd COMPOUNDS WITH ACTIVITY AT THE M1 RECEPTOR AND THEIR USE IN MEDICINE
JP5209479B2 (en) * 2005-09-30 2013-06-12 グラクソ グループ リミテッド Benzimidazolones having activity at the M1 receptor
US8288412B2 (en) 2005-09-30 2012-10-16 Glaxo Group Limited Compounds which have activity at M1 receptor and their uses in medicine
TW200813018A (en) * 2006-06-09 2008-03-16 Astrazeneca Ab Novel compounds
TW200815405A (en) * 2006-06-09 2008-04-01 Astrazeneca Ab Novel compounds
EP3101018B1 (en) * 2007-08-31 2019-03-06 Purdue Pharma L.P. Substituted-quinoxaline-type-piperidine compounds and the uses thereof
US8119661B2 (en) 2007-09-11 2012-02-21 Astrazeneca Ab Piperidine derivatives and their use as muscarinic receptor modulators
AR068480A1 (en) 2007-09-20 2009-11-18 Glaxo Group Ltd COMPOSITE OF 4-HETEROARIL-PIPERIDINIL-N-SUBSTITUTED ITS USE FOR THE PREPARATION OF A USEFUL MEDICINAL PRODUCT FOR THE TREATMENT OF AN AFFECTION IN WHICH THE AGONISM OF A M1 MUSCARINIC RECEIVER AND PHARMACEUTICAL COMPOSITION THAT UNDERSTAND IT
WO2009037294A1 (en) * 2007-09-20 2009-03-26 Glaxo Group Limited Compounds which have activity at m1 receptor and their uses in medicine
GB0718415D0 (en) * 2007-09-20 2007-10-31 Glaxo Group Ltd Compounds
UY31672A1 (en) * 2008-02-28 2009-09-30 "MUSCARINIC RECEPTORS AGONISTS PHARMACEUTICAL COMPOSITIONS METHODS OF TREATMENT OF THE SAME, AND PROCEDURES FOR THEIR PREPARATION"
WO2009124883A1 (en) * 2008-04-09 2009-10-15 H. Lundbeck A/S Novel 1,3-dihydro-benzoimidazol-2-ones as m1 agonists
GB0817982D0 (en) * 2008-10-01 2008-11-05 Glaxo Group Ltd Compounds
US9187451B2 (en) 2011-11-18 2015-11-17 Heptares Therapeutics Limited Muscarinic M1 receptor agonists
JP2015083543A (en) * 2012-02-14 2015-04-30 大日本住友製薬株式会社 Novel condensed-ring pyrrolidine derivative
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9593106B2 (en) 2013-02-07 2017-03-14 Heptares Therapeutics Limited Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
ES2789756T3 (en) 2015-12-23 2020-10-26 Merck Sharp & Dohme Allosteric modulators of 6,7-dihydro-5H-pyrrolo [3,4-b] pyridin-5-one of the muscarinic acetylcholine receptor M4
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
WO2018112842A1 (en) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. 6,6-fused heteroaryl piperidine ether allosteric modulators of m4 muscarinic acetylcholine receptor
WO2018112843A1 (en) 2016-12-22 2018-06-28 Merck Sharp & Dohme Corp. Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
KR20210145787A (en) 2019-04-02 2021-12-02 알리고스 테라퓨틱스 인코포레이티드 Compounds targeting PRMT5
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4407961A1 (en) * 1994-03-10 1995-09-14 Thomae Gmbh Dr K Imidazolidin-2-one, medicaments containing these compounds and process for their preparation
US5691323A (en) * 1995-05-12 1997-11-25 Merck & Co., Inc. Muscarine antagonists
US5574044A (en) * 1994-10-27 1996-11-12 Merck & Co., Inc. Muscarine antagonists
WO1997016192A1 (en) * 1995-10-31 1997-05-09 Merck & Co., Inc. Muscarine antagonists
WO1997016186A1 (en) * 1995-10-31 1997-05-09 Merck & Co., Inc. Muscarine agonists
TW531537B (en) * 1995-12-27 2003-05-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-substituted piperidine derivatives

Also Published As

Publication number Publication date
WO1999032481A1 (en) 1999-07-01

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase