GB201322602D0 - Pharmaceutical compounds - Google Patents

Pharmaceutical compounds

Info

Publication number
GB201322602D0
GB201322602D0 GBGB1322602.2A GB201322602A GB201322602D0 GB 201322602 D0 GB201322602 D0 GB 201322602D0 GB 201322602 A GB201322602 A GB 201322602A GB 201322602 D0 GB201322602 D0 GB 201322602D0
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1322602.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almac Discovery Ltd
Original Assignee
Almac Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almac Discovery Ltd filed Critical Almac Discovery Ltd
Priority to GBGB1322602.2A priority Critical patent/GB201322602D0/en
Publication of GB201322602D0 publication Critical patent/GB201322602D0/en
Priority to KR1020167019551A priority patent/KR102405462B1/ko
Priority to ES14815843.9T priority patent/ES2650013T3/es
Priority to CN201480069437.9A priority patent/CN105829315B/zh
Priority to RU2016123363A priority patent/RU2691105C1/ru
Priority to DK14815843.9T priority patent/DK3083625T3/en
Priority to AU2014369457A priority patent/AU2014369457B2/en
Priority to PL14815843T priority patent/PL3083625T3/pl
Priority to SM20180020T priority patent/SMT201800020T1/it
Priority to PT148158439T priority patent/PT3083625T/pt
Priority to MX2016007801A priority patent/MX371108B/es
Priority to US15/105,869 priority patent/US9850247B2/en
Priority to CA2933755A priority patent/CA2933755C/en
Priority to LTEP14815843.9T priority patent/LT3083625T/lt
Priority to JP2016541294A priority patent/JP6437559B2/ja
Priority to EP14815843.9A priority patent/EP3083625B1/en
Priority to SI201430580T priority patent/SI3083625T1/en
Priority to BR112016014151-2A priority patent/BR112016014151B1/pt
Priority to HUE14815843A priority patent/HUE037908T2/hu
Priority to HRP20180080TT priority patent/HRP20180080T1/hr
Priority to PCT/GB2014/053793 priority patent/WO2015092431A1/en
Priority to NO14815843A priority patent/NO3083625T3/no
Priority to SG11201603814TA priority patent/SG11201603814TA/en
Priority to RS20171338A priority patent/RS56731B1/sr
Priority to NZ720178A priority patent/NZ720178A/en
Priority to IL245672A priority patent/IL245672B/en
Priority to ZA2016/03337A priority patent/ZA201603337B/en
Priority to CY20181100041T priority patent/CY1120035T1/el
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB1322602.2A 2013-12-19 2013-12-19 Pharmaceutical compounds Ceased GB201322602D0 (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
GBGB1322602.2A GB201322602D0 (en) 2013-12-19 2013-12-19 Pharmaceutical compounds
NZ720178A NZ720178A (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
CA2933755A CA2933755C (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
JP2016541294A JP6437559B2 (ja) 2013-12-19 2014-12-19 Wee−1キナーゼ阻害剤として有用なピリミドピリミジノン
CN201480069437.9A CN105829315B (zh) 2013-12-19 2014-12-19 可用作Wee-1激酶抑制剂的嘧啶并嘧啶酮类
RU2016123363A RU2691105C1 (ru) 2013-12-19 2014-12-19 Лекарственные соединения
DK14815843.9T DK3083625T3 (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
AU2014369457A AU2014369457B2 (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as Wee-1 kinase inhibitors
PL14815843T PL3083625T3 (pl) 2013-12-19 2014-12-19 Pirymidopirymidynony użyteczne jako inhibitory kinazy wee-1
SM20180020T SMT201800020T1 (it) 2013-12-19 2014-12-19 Pirimidopirimidinoni utili come inibitori della chinasi wee-1
PT148158439T PT3083625T (pt) 2013-12-19 2014-12-19 Pirimidopirimidinonas úteis como inibidores da cinase wee-1
MX2016007801A MX371108B (es) 2013-12-19 2014-12-19 Pirimidopirimidinonas utiles como iniciadores de wee-1 cinasa.
US15/105,869 US9850247B2 (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as Wee-1 kinase inhibitors
KR1020167019551A KR102405462B1 (ko) 2013-12-19 2014-12-19 Wee-1 카이네이즈 억제제로 유용한 피리미도피리미디논
LTEP14815843.9T LT3083625T (lt) 2013-12-19 2014-12-19 Pirimidopirimidinonai, tinkami naudoti kaip wee-1 kinazės inhibitoriai
ES14815843.9T ES2650013T3 (es) 2013-12-19 2014-12-19 Pirimidopirimidinonas útiles como inhibidores de la quinasa Wee-1
EP14815843.9A EP3083625B1 (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
SI201430580T SI3083625T1 (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones, useful as Wee-1 kinase inhibitors
BR112016014151-2A BR112016014151B1 (pt) 2013-12-19 2014-12-19 Pirirmidopirimidinonas úteis como inibidores de quinases wee-1
HUE14815843A HUE037908T2 (hu) 2013-12-19 2014-12-19 Pirimodopirimidononok mint WEE-1 kináz inhibitorok
HRP20180080TT HRP20180080T1 (hr) 2013-12-19 2014-12-19 Pirimidopirimidinoni korisni kao inhibitori wee-1 kinaze
PCT/GB2014/053793 WO2015092431A1 (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
NO14815843A NO3083625T3 (enExample) 2013-12-19 2014-12-19
SG11201603814TA SG11201603814TA (en) 2013-12-19 2014-12-19 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
RS20171338A RS56731B1 (sr) 2013-12-19 2014-12-19 Pirimidopirimidinoni korisni kao inhibitori wee-1 kinaze
ZA2016/03337A ZA201603337B (en) 2013-12-19 2016-05-17 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
IL245672A IL245672B (en) 2013-12-19 2016-05-17 Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
CY20181100041T CY1120035T1 (el) 2013-12-19 2018-01-15 Πυριμιδοπυριμιδινονες χρησιμες ως αναστολεις της wee-1 κινασης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1322602.2A GB201322602D0 (en) 2013-12-19 2013-12-19 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
GB201322602D0 true GB201322602D0 (en) 2014-02-05

Family

ID=50071157

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1322602.2A Ceased GB201322602D0 (en) 2013-12-19 2013-12-19 Pharmaceutical compounds

Country Status (28)

Country Link
US (1) US9850247B2 (enExample)
EP (1) EP3083625B1 (enExample)
JP (1) JP6437559B2 (enExample)
KR (1) KR102405462B1 (enExample)
CN (1) CN105829315B (enExample)
AU (1) AU2014369457B2 (enExample)
BR (1) BR112016014151B1 (enExample)
CA (1) CA2933755C (enExample)
CY (1) CY1120035T1 (enExample)
DK (1) DK3083625T3 (enExample)
ES (1) ES2650013T3 (enExample)
GB (1) GB201322602D0 (enExample)
HR (1) HRP20180080T1 (enExample)
HU (1) HUE037908T2 (enExample)
IL (1) IL245672B (enExample)
LT (1) LT3083625T (enExample)
MX (1) MX371108B (enExample)
NO (1) NO3083625T3 (enExample)
NZ (1) NZ720178A (enExample)
PL (1) PL3083625T3 (enExample)
PT (1) PT3083625T (enExample)
RS (1) RS56731B1 (enExample)
RU (1) RU2691105C1 (enExample)
SG (1) SG11201603814TA (enExample)
SI (1) SI3083625T1 (enExample)
SM (1) SMT201800020T1 (enExample)
WO (1) WO2015092431A1 (enExample)
ZA (1) ZA201603337B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10364247B2 (en) * 2015-04-21 2019-07-30 Ruijin Hospital Affiliated To Shanghai Jiao Tong University School Of Medicine Preparation and use of novel protein kinase inhibitors
CA3003737C (en) * 2015-11-01 2021-09-14 The Regents Of The University Of Colorado, A Body Corporate Wee1 kinase inhibitors and methods of making and using the same
CA3043945A1 (en) 2016-11-16 2018-05-24 Sui Xiong Cai 8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6h)-ones
US10954216B2 (en) 2016-12-27 2021-03-23 Riken BMP-signal-inhibiting compound
CN110198943B (zh) * 2017-01-23 2021-04-16 石家庄智康弘仁新药开发有限公司 作为Wee1抑制剂的1,2-二氢-3H-吡唑[3,4-d]嘧啶-3-酮衍生物
GB201703881D0 (en) * 2017-03-10 2017-04-26 Almac Discovery Ltd Pharmaceutical compounds
SG11201908788YA (en) 2017-03-31 2019-10-30 Seattle Genetics Inc Combinations of chk1- and wee1 - inhibitors
CN110914277B (zh) * 2017-07-10 2022-08-09 上海瑛派药业有限公司 咪唑并[1,2-b]嘧啶并[4,5-d]哒嗪-5(6H)-酮类化合物及其应用
CN109422754A (zh) * 2017-08-24 2019-03-05 上海迪诺医药科技有限公司 吡唑并[3,4-d]嘧啶-3-酮衍生物、其药物组合物及应用
WO2019074979A1 (en) 2017-10-09 2019-04-18 Girafpharma, Llc HETEROCYCLIC COMPOUNDS AND USES THEREOF
AU2018347307A1 (en) 2017-10-09 2020-04-23 Nuvation Bio Inc. Heterocyclic compounds and uses thereof
WO2019085933A1 (zh) 2017-11-01 2019-05-09 南京明德新药研发股份有限公司 作为Wee1抑制剂的大环类化合物及其应用
WO2019169065A2 (en) * 2018-02-28 2019-09-06 The Regents Of The University Of Colorado, A Body Corporate Wee1 kinase inhibitors and methods of treating cancer using the same
MX2021003531A (es) * 2018-09-27 2021-07-21 Betta Pharmaceuticals Co Ltd Inhibidor de fgfr4 y su uso.
US12180184B2 (en) 2018-10-26 2024-12-31 Wuxi Biocity Biopharmaceutics Co., Ltd. Pyrimidopyrazolone derivative as Wee1 inhibitor and use thereof
EP3902805A4 (en) 2018-12-28 2023-03-01 SPV Therapeutics Inc. CYCLINE-DEPENDENT KINASE INHIBITORS
KR102697799B1 (ko) 2019-03-22 2024-08-23 쇼우야오 홀딩스 (베이징) 코., 엘티디. Wee1 억제제 및 이의 제조 및 용도
EP3952878A4 (en) * 2019-04-09 2023-01-04 Nuvation Bio Inc. HETEROCYCLIC COMPOUNDS AND THEIR USES
CN113939296A (zh) 2019-04-09 2022-01-14 诺维逊生物股份有限公司 杂环化合物及其用途
EP3952879A4 (en) * 2019-04-09 2023-01-04 Nuvation Bio Inc. HETEROCYCLIC COMPOUNDS AND THEIR USES
HRP20241008T1 (hr) 2019-04-30 2024-11-08 Wuxi Biocity Biopharmaceutics Co., Ltd. Kristalni oblik spoja inhibitora wee1 i njegova uporaba
CN112142763B (zh) * 2019-06-28 2024-01-26 上海医药集团股份有限公司 一种吡唑酮并嘧啶类化合物、其制备方法及应用
CN115698006B (zh) 2020-06-17 2024-03-29 微境生物医药科技(上海)有限公司 作为Wee-1抑制剂的吡唑并[3,4-d]嘧啶-3-酮衍生物
EP4221710A4 (en) * 2020-10-01 2024-09-18 University of Washington DRUG-LIKE MOLECULES AND METHODS FOR THERAPEUTIC TARGETING OF MICRORNA-21
TW202239409A (zh) * 2020-12-18 2022-10-16 英商葛蘭素史密斯克藍智慧財產發展有限公司 化合物
MX2023007244A (es) * 2020-12-18 2023-06-29 Glaxosmithkline Ip Dev Ltd Compuestos quimicos utiles para inhibir los canales de sodio activados por voltaje de nav1.8 y tratar las enfermedades mediadas por nav1.8.
JP2024515318A (ja) 2021-04-30 2024-04-08 ウィゲン・バイオメディシン・テクノロジー・(シャンハイ)・カンパニー・リミテッド Wee-1阻害剤としての縮合環状化合物、その調製方法およびその使用
WO2022270994A1 (ko) 2021-06-25 2022-12-29 한국화학연구원 유비퀴틴 프로테오좀 경로를 통해 비티케이 분해작용을 가지는 신규한 이작용성 헤테로사이클릭 화합물과 이의 용도
CN116462687B (zh) 2022-01-18 2025-01-07 江苏天士力帝益药业有限公司 Wee1抑制剂及其制备和用途
CN116836184B (zh) * 2022-03-25 2025-07-25 药雅科技(上海)有限公司 Wee1激酶抑制剂的制备及其应用
WO2023217201A2 (zh) * 2022-05-10 2023-11-16 杭州德睿智药科技有限公司 作为Wee1抑制剂的新型嘧啶并杂环类新化合物及其应用
CN117402162A (zh) 2022-07-13 2024-01-16 江苏天士力帝益药业有限公司 Wee1抑制剂及其制备和用途
TW202519226A (zh) 2023-11-08 2025-05-16 美商艾克塞里克斯公司 使用抑制pkmyt1之化合物治療癌症之方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7504396B2 (en) 2003-06-24 2009-03-17 Amgen Inc. Substituted heterocyclic compounds and methods of use
WO2005090344A1 (en) 2004-03-15 2005-09-29 F. Hoffmann-La Roche Ag Novel dichloro-phenyl-pyrido [2,3-d] pyrimidine derivates, their manufacture and use as pharmaceutical agents
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP5411847B2 (ja) 2007-04-25 2014-02-12 Msd株式会社 Weelキナーゼインヒビターとしてのジヒドロピラゾロピリミジノン誘導体の多形
MX2009013728A (es) 2007-06-15 2010-01-25 Banyu Pharma Co Ltd Derivados de bicicloanilina.
EP2213673B1 (en) 2007-10-23 2013-06-05 Msd K.K. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
CA2745959A1 (en) * 2008-12-12 2010-06-17 Msd K.K. Dihydropyrimidopyrimidine derivatives
WO2010067886A1 (en) 2008-12-12 2010-06-17 Banyu Pharmaceutical Co.,Ltd. Dihydropyrimidopyrimidine derivative
JP5886310B2 (ja) * 2010-12-06 2016-03-16 グラクソ グループ リミテッドGlaxo Group Limited Lp−PLA2により媒介される疾患または状態の処置における使用のためのピリミジノン化合物
AR084515A1 (es) * 2010-12-22 2013-05-22 Merz Pharma Gmbh & Co Kgaa Derivados heterociclicos nitrogenados, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento de enfermedades asociadas al sistema nervioso central tales como parkinson y alzheimer, entre otras
TWI532742B (zh) 2011-02-28 2016-05-11 艾伯維有限公司 激酶之三環抑制劑
WO2013012681A1 (en) 2011-07-15 2013-01-24 Abbott Laboratories Tricyclic inhibitors of kinases useful for the treatment of proliferative diseases
US8796289B2 (en) 2011-07-19 2014-08-05 Abbvie Inc. Pyridazino[4,5-D]pyrimidin-5(6H)-one inhibitors of kinases
JP2014530867A (ja) 2011-10-20 2014-11-20 アッヴィ・インコーポレイテッド キナーゼのピリドピリミジノン阻害剤
CA2864142A1 (en) * 2012-02-23 2013-08-29 Abbvie Inc. Pyridopyrimidinone inhibitors of kinases
CN102816164A (zh) * 2012-08-31 2012-12-12 北京理工大学 一种合成7-氨基-2,3-二氢嘧啶[4,5-d]嘧啶-4(1H)-酮的方法

Also Published As

Publication number Publication date
HRP20180080T1 (hr) 2018-03-09
CN105829315A (zh) 2016-08-03
DK3083625T3 (en) 2017-12-18
CA2933755A1 (en) 2015-06-25
BR112016014151B1 (pt) 2023-01-17
CY1120035T1 (el) 2018-12-12
ES2650013T3 (es) 2018-01-16
EP3083625A1 (en) 2016-10-26
KR102405462B1 (ko) 2022-06-03
US20160318936A1 (en) 2016-11-03
PL3083625T3 (pl) 2018-03-30
CN105829315B (zh) 2019-03-08
ZA201603337B (en) 2018-07-25
EP3083625B1 (en) 2017-11-01
SG11201603814TA (en) 2016-07-28
NZ720178A (en) 2022-05-27
BR112016014151A2 (enExample) 2017-08-08
AU2014369457A1 (en) 2016-06-09
RU2016123363A (ru) 2018-01-25
RS56731B1 (sr) 2018-03-30
SMT201800020T1 (it) 2018-05-02
IL245672B (en) 2021-10-31
MX371108B (es) 2020-01-17
RU2691105C1 (ru) 2019-06-11
PT3083625T (pt) 2018-02-06
KR20160098499A (ko) 2016-08-18
HUE037908T2 (hu) 2018-09-28
AU2014369457B2 (en) 2018-08-09
IL245672A0 (en) 2016-06-30
JP2017500335A (ja) 2017-01-05
JP6437559B2 (ja) 2018-12-12
MX2016007801A (es) 2016-09-07
SI3083625T1 (en) 2018-03-30
US9850247B2 (en) 2017-12-26
NO3083625T3 (enExample) 2018-03-31
LT3083625T (lt) 2017-12-27
CA2933755C (en) 2023-01-31
WO2015092431A1 (en) 2015-06-25

Similar Documents

Publication Publication Date Title
GB201322602D0 (en) Pharmaceutical compounds
GB201306610D0 (en) Pharmaceutical compounds
IL240846A0 (en) drug combination
AP2015008713A0 (en) Tetrahydropyrrolothiazine compounds
GB201302927D0 (en) Compounds
ZA201602047B (en) Pharmaceutical compounds
AP3850A (en) Azetidinyloxyphenylpyrrolidine compounds
SG11201601477VA (en) Pharmaceutical composition
ZA201600027B (en) Pharmaceutical preparation
GB201312386D0 (en) Pharmaceutical compounds
EP2948457A4 (en) COMPOUNDS
GB201306794D0 (en) Compounds
IL244365A0 (en) pharmaceutical preparation
GB201317166D0 (en) Pharmaceutical compounds
GB201316791D0 (en) Pharmaceutical Compounds
GB201316780D0 (en) Pharmaceutical compounds
GB201315733D0 (en) Pharmaceutical compounds
GB201315734D0 (en) Pharmaceutical compounds
GB201312464D0 (en) Pharmaceutical compounds
GB201308781D0 (en) Pharmaceutical compounds
GB201308782D0 (en) Pharmaceutical compounds
GB201308780D0 (en) Pharmaceutical compounds
GB201321316D0 (en) Pharmaceutical Compound
GB201309405D0 (en) Pharmaceutical compound
GB201316662D0 (en) Pharmaceutical Combination

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)