GB1574566A - Cell characterisation apparatus - Google Patents

Cell characterisation apparatus Download PDF

Info

Publication number
GB1574566A
GB1574566A GB8468/78A GB846878A GB1574566A GB 1574566 A GB1574566 A GB 1574566A GB 8468/78 A GB8468/78 A GB 8468/78A GB 846878 A GB846878 A GB 846878A GB 1574566 A GB1574566 A GB 1574566A
Authority
GB
United Kingdom
Prior art keywords
cells
wall portion
passage
flow
plane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8468/78A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1574566A publication Critical patent/GB1574566A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
GB8468/78A 1977-03-04 1978-03-03 Cell characterisation apparatus Expired GB1574566A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2709399A DE2709399C3 (de) 1977-03-04 1977-03-04 Einrichtung zum Messen von Zelleigenschaften

Publications (1)

Publication Number Publication Date
GB1574566A true GB1574566A (en) 1980-09-10

Family

ID=6002741

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8468/78A Expired GB1574566A (en) 1977-03-04 1978-03-03 Cell characterisation apparatus

Country Status (5)

Country Link
US (1) US4225229A (enExample)
CH (1) CH626725A5 (enExample)
DE (1) DE2709399C3 (enExample)
FR (1) FR2382691A1 (enExample)
GB (1) GB1574566A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000282A1 (en) * 1985-07-10 1987-01-15 Harald Steen A flow chamber device for flow cytometers

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU938936A1 (ru) * 1978-11-01 1982-06-30 Институт биологической физики АН СССР Устройство дл поиска измененных клеток в цитологическом препарате
US4408877A (en) 1979-04-10 1983-10-11 Ernst Leitz Wetzlar Gmbh Device for hydrodynamic focussing of a particle-suspension in a liquid flow cytophotometer
US4348107A (en) * 1980-07-18 1982-09-07 Coulter Electronics, Inc. Orifice inside optical element
IT1171329B (it) * 1981-06-25 1987-06-10 B I M Srl Dispositivo per la valutazione obiettiva cella concentrazione e della motilita' degli speramtozoi in campioni di liquido seminale con sistema elettronico di elaborazione e presentazione dei risultati di analisi
DE3233055C2 (de) * 1982-09-06 1994-07-28 Coulter Electronics Durchflußvorrichtung zur Untersuchung einzelner, in einer Flüssigkeit suspendierter Teilchen
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
DE3420018A1 (de) * 1984-05-29 1985-12-05 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Vorrichtung zur messung bestimmter eigenschaften in einem traegermedium suspendierter partikel
US4661913A (en) * 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
JPH0652263B2 (ja) * 1985-12-10 1994-07-06 株式会社日立製作所 細胞分析装置
EP0286855A1 (de) * 1987-04-15 1988-10-19 BBC Brown Boveri AG Verfahren zum Aetzen von Vertiefungen in ein Siliziumsubstrat
DE3718407A1 (de) * 1987-06-02 1988-12-22 Hund Helmut Gmbh Anordnung fuer die optische analyse von partikelpopulationen in gasen und fluessigkeiten
US4945974A (en) * 1988-02-05 1990-08-07 Reynolds Metals Company Apparatus for and process of direct casting of metal strip
US4954715A (en) * 1989-06-26 1990-09-04 Zoeld Tibor Method and apparatus for an optimized multiparameter flow-through particle and cell analyzer
DE4221063C2 (de) * 1992-06-26 1994-06-01 Thomas Dr Heiden Optisches System für Auflicht-Fluoreszenzmikroskop zur Beobachtung mehrer Fluoreszenzvorgänge
IT1272120B (it) * 1993-03-22 1997-06-11 Bio Rad Spd Srl Camera di misurazione per citometro a flusso
JP4323571B2 (ja) 1997-01-31 2009-09-02 エックスワイ， インコーポレイテッド 光学装置
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6400453B1 (en) 1998-08-21 2002-06-04 Union Biometrica, Inc. Instrument for selecting and depositing multicellular organisms and other large objects
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002043574A2 (en) 2000-11-29 2002-06-06 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
US8211629B2 (en) 2002-08-01 2012-07-03 Xy, Llc Low pressure sperm cell separation system
CA2534394C (en) 2002-08-15 2013-01-08 Xy, Inc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
DK2308419T3 (da) 2003-03-28 2016-06-06 Inguran Llc Fremgangsmåde til bedømmelse af farvningstilstandene for dyresperm, som skal sorteres.
EP1625203B1 (en) 2003-05-15 2015-04-08 Xy, Llc Efficient haploid cell sorting for flow cytometer systems
JP2005030831A (ja) * 2003-07-09 2005-02-03 Aisin Seiki Co Ltd セルソータ用光照射装置
WO2005095590A2 (en) 2004-03-29 2005-10-13 Monsanto Technology Llc Sperm suspensions for sorting into x or y chromosome-bearing enriched populations
AR049732A1 (es) 2004-07-22 2006-08-30 Monsanto Co Proceso para enriquecer una poblacion de celulas de esperma
FI120634B (fi) * 2007-08-17 2009-12-31 Kari Seppaelae Menetelmä ja laitteisto näytteen ottamiseksi
US10900885B2 (en) 2014-12-19 2021-01-26 Captl Llc Flow cytometry using hydrodynamically planar flow
WO2016099538A1 (en) 2014-12-19 2016-06-23 Captl Llc Flow cytometry using hydrodynamically planar flow
DE102020000677B4 (de) 2020-02-01 2023-01-12 Hochschule Anhalt Universaldurchflussmessgerät und Verfahren zur Steuerung eines Universaldurchflussmessgeräts

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1815352C3 (de) * 1968-12-18 1975-03-20 Wolfgang Prof. Dr. Dittrich Automatisches MeB- und Zählgerät für die Teilchen einer Dispersion
US3788744A (en) * 1970-01-14 1974-01-29 Bio Physics Systems Inc Method and apparatus for photoanalysis
US3740665A (en) * 1972-03-16 1973-06-19 Avco Corp Transverse flowing liquid laser
DE7333009U (de) 1972-09-15 1974-03-07 Applied Research Laboratories Ltd Durchflußküvette
US3811777A (en) * 1973-02-06 1974-05-21 Johnson Res Foundation Medical Time-sharing fluorometer and reflectometer
US3984307A (en) * 1973-03-05 1976-10-05 Bio/Physics Systems, Inc. Combined particle sorter and segregation indicator
US3916205A (en) * 1973-05-31 1975-10-28 Block Engineering Differential counting of leukocytes and other cells
US3902807A (en) * 1973-10-25 1975-09-02 Du Pont Method for operating an attenuated total reflection infrared system
US3897154A (en) * 1973-11-15 1975-07-29 Roland C Hawes Sample-background autocancellation in fluid-sample analyzers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000282A1 (en) * 1985-07-10 1987-01-15 Harald Steen A flow chamber device for flow cytometers
EP0229814B1 (en) * 1985-07-10 1989-05-31 STEEN, Harald A flow chamber device for flow cytometers

Also Published As

Publication number Publication date
DE2709399C3 (de) 1980-07-24
FR2382691B1 (enExample) 1982-07-09
DE2709399A1 (de) 1978-09-07
FR2382691A1 (fr) 1978-09-29
DE2709399B2 (de) 1979-11-08
CH626725A5 (enExample) 1981-11-30
US4225229A (en) 1980-09-30

Similar Documents

Publication Publication Date Title
US4225229A (en) Apparatus for measuring cytological properties
US4673289A (en) Optical device with a high collection efficiency and cytofluorimeter making use of the same
EP0689672B1 (en) An optical arrangement for flow cytometers
US4200802A (en) Parabolic cell analyzer
US3497690A (en) Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof
JP3891925B2 (ja) 生物学的粒子の情報を得る装置
EP0068404B1 (en) Analyzer for simultaneously determining volume and light emission characteristics of particles
US7800754B2 (en) Optical arrangement for a flow cytometer
US4915501A (en) Device for measuring the light scattering of biological cells in flow cytophotometers
EP0210343A1 (en) Flow cytometry apparatus with improved light beam adjustment
US3999855A (en) Illumination system
US11150458B2 (en) Multi-mode imaging optical system
JPH05340865A (ja) 測定装置
US3950649A (en) Vertical reflection type fluorescence microphotometer
GB2125181A (en) Flow cells for particle study
JPH06160724A (ja) フラッシュフォトリシス用顕微鏡
GB1389553A (en) Apparatus for investigating microscopic particles
US4351611A (en) Monitoring of a detection zone utilizing zero order radiation from a concave reflecting grating
Rost et al. An improved microspectrofluorimeter with automatic digital data logging: construction and operation
Young Principles and technique of fluorescence microscopy
US11867607B2 (en) Electro-optical device for taking measurements of flow
JP2010286381A (ja) フローサイトメーター
JPH0552895B2 (enExample)
US5404238A (en) Flashlight illuminating apparatus for a microscope
JPH03266809A (ja) 紫外域用落射蛍光顕微鏡

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee