GB1570625A - Glucosamine derivatives and a process for their manufacture - Google Patents

Glucosamine derivatives and a process for their manufacture Download PDF

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Publication number
GB1570625A
GB1570625A GB51228/76A GB5122876A GB1570625A GB 1570625 A GB1570625 A GB 1570625A GB 51228/76 A GB51228/76 A GB 51228/76A GB 5122876 A GB5122876 A GB 5122876A GB 1570625 A GB1570625 A GB 1570625A
Authority
GB
United Kingdom
Prior art keywords
carbamoyl
denotes
deoxy
benzyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB51228/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1570625A publication Critical patent/GB1570625A/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB51228/76A 1975-12-10 1976-12-08 Glucosamine derivatives and a process for their manufacture Expired GB1570625A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (1)

Publication Number Publication Date
GB1570625A true GB1570625A (en) 1980-07-02

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
GB51228/76A Expired GB1570625A (en) 1975-12-10 1976-12-08 Glucosamine derivatives and a process for their manufacture

Country Status (30)

Country Link
JP (1) JPS5273820A (ru)
AR (2) AR224091A1 (ru)
AT (1) AT365607B (ru)
AU (1) AU508764B2 (ru)
BE (1) BE849214A (ru)
CA (1) CA1262400A (ru)
CH (2) CH613709A5 (ru)
CS (4) CS205027B2 (ru)
DD (1) DD129781A5 (ru)
DE (1) DE2655500A1 (ru)
DK (1) DK154654C (ru)
ES (2) ES454118A1 (ru)
FI (1) FI64164C (ru)
FR (1) FR2361902A1 (ru)
GB (1) GB1570625A (ru)
GR (1) GR61647B (ru)
HK (1) HK32883A (ru)
HU (1) HU177970B (ru)
IE (1) IE44190B1 (ru)
IL (1) IL51076A (ru)
MY (1) MY8400123A (ru)
NL (1) NL7613666A (ru)
NO (1) NO144850C (ru)
NZ (1) NZ182837A (ru)
PL (4) PL110787B1 (ru)
PT (1) PT65946B (ru)
SE (1) SE445923B (ru)
SG (1) SG11083G (ru)
SU (3) SU660589A3 (ru)
ZA (1) ZA767333B (ru)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4323560A (en) 1979-10-12 1982-04-06 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4414204A (en) 1979-07-25 1983-11-08 Ciba-Geigy Corporation Antibiotic preparations having increased effectiveness, processes for their manufacture and method for increasing the antibiotic action of antibiotics
US4681856A (en) * 1983-08-18 1987-07-21 Toshiyuki Hamaoka Daiichi Seiyaku Co., Ltd. Muramyldipeptide active ester derivatives
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
EP3389643A4 (en) * 2015-12-15 2019-07-10 Bharat Biotech International Limited NOVEL COMPOUND DERIVED FROM MURAMYL PEPTIDES, SYNTHESIS AND USES THEREOF
EP3387005A4 (en) * 2015-12-10 2019-07-10 Bharat Biotech International Limited NEW COMPOUND DERIVED FROM MURAMYL, SYNTHESIS AND USES THEREOF
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
CH636887A5 (en) * 1976-04-26 1983-06-30 Syntex Inc Process for the preparation of novel immunological adjuvant compounds
EP0002677B1 (en) 1977-12-02 1982-10-13 Takeda Chemical Industries, Ltd. Glucosamine-peptide derivatives and their pharmaceutical compositions
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
EP0003833B2 (de) * 1978-02-24 1990-12-19 Ciba-Geigy Ag Antigenderivate, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Präparate
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
US4256735A (en) * 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
EP0026746B1 (de) * 1979-10-02 1985-04-10 Ciba-Geigy Ag Kombinationspräparate zur Anwendung in einem Verfahren zur Steigerung der Wirkung von Antibiotika, antibiotische Präparate mit gesteigerter Wirksamkeit und Verfahren zu deren Herstellung
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (de) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika
GR78246B (ru) * 1981-01-23 1984-09-26 Ciba Geigy Ag
EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
WO2019040109A1 (en) 2017-08-21 2019-02-28 Celgene Corporation PROCESSES FOR THE PREPARATION OF (S) -TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414204A (en) 1979-07-25 1983-11-08 Ciba-Geigy Corporation Antibiotic preparations having increased effectiveness, processes for their manufacture and method for increasing the antibiotic action of antibiotics
US4323560A (en) 1979-10-12 1982-04-06 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4681856A (en) * 1983-08-18 1987-07-21 Toshiyuki Hamaoka Daiichi Seiyaku Co., Ltd. Muramyldipeptide active ester derivatives
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
EP3387005A4 (en) * 2015-12-10 2019-07-10 Bharat Biotech International Limited NEW COMPOUND DERIVED FROM MURAMYL, SYNTHESIS AND USES THEREOF
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
EP3389643A4 (en) * 2015-12-15 2019-07-10 Bharat Biotech International Limited NOVEL COMPOUND DERIVED FROM MURAMYL PEPTIDES, SYNTHESIS AND USES THEREOF

Also Published As

Publication number Publication date
NO144850B (no) 1981-08-17
IL51076A0 (en) 1977-02-28
SU747430A3 (ru) 1980-07-23
GR61647B (en) 1978-12-05
CS205027B2 (en) 1981-04-30
PL110353B1 (en) 1980-07-31
PL110787B1 (en) 1980-07-31
DK154654C (da) 1989-05-08
HK32883A (en) 1983-09-02
BE849214A (fr) 1977-06-09
JPS638118B2 (ru) 1988-02-19
PL194291A1 (pl) 1978-10-23
NL7613666A (nl) 1977-06-14
CS205025B2 (en) 1981-04-30
DE2655500A1 (de) 1977-06-23
SE445923B (sv) 1986-07-28
AU2042276A (en) 1978-06-15
AR224091A1 (es) 1981-10-30
HU177970B (en) 1982-02-28
SG11083G (en) 1983-09-16
DK154654B (da) 1988-12-05
IL51076A (en) 1980-09-16
CS205026B2 (en) 1981-04-30
ES454118A1 (es) 1978-03-01
FI64164C (fi) 1983-10-10
DE2655500C2 (ru) 1988-12-22
IE44190L (en) 1977-06-10
NZ182837A (en) 1978-07-28
SU1060118A3 (ru) 1983-12-07
DK552476A (da) 1977-06-11
FI64164B (fi) 1983-06-30
DD129781A5 (de) 1978-02-08
PL110794B1 (en) 1980-07-31
IE44190B1 (en) 1981-09-09
FI763541A (ru) 1977-06-11
AR220686A1 (es) 1980-11-28
CA1262400A (en) 1989-10-17
CH614718A5 (en) 1979-12-14
MY8400123A (en) 1984-12-31
NO764191L (ru) 1977-06-13
CS205028B2 (en) 1981-04-30
PT65946A (en) 1977-01-01
ZA767333B (en) 1977-11-30
PL112672B1 (en) 1980-10-31
AU508764B2 (en) 1980-04-03
NO144850C (no) 1981-11-25
SE7613851L (sv) 1977-06-11
AT365607B (de) 1982-02-10
PT65946B (en) 1978-06-14
ATA909276A (de) 1981-06-15
CH613709A5 (en) 1979-10-15
SU660589A3 (ru) 1979-04-30
ES465514A1 (es) 1978-09-16
JPS5273820A (en) 1977-06-21
FR2361902A1 (fr) 1978-03-17
FR2361902B1 (ru) 1980-11-07

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19931208