GB1560406A - Solid solutions of ergot alkaholids in polymers - Google Patents

Solid solutions of ergot alkaholids in polymers Download PDF

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Publication number
GB1560406A
GB1560406A GB42907/76A GB4290776A GB1560406A GB 1560406 A GB1560406 A GB 1560406A GB 42907/76 A GB42907/76 A GB 42907/76A GB 4290776 A GB4290776 A GB 4290776A GB 1560406 A GB1560406 A GB 1560406A
Authority
GB
United Kingdom
Prior art keywords
composition
polymer
solid
weight
molecular weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB42907/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1560406A publication Critical patent/GB1560406A/en
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB42907/76A 1975-10-17 1976-10-15 Solid solutions of ergot alkaholids in polymers Expired GB1560406A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2546577A DE2546577B2 (de) 1975-10-17 1975-10-17 Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden

Publications (1)

Publication Number Publication Date
GB1560406A true GB1560406A (en) 1980-02-06

Family

ID=5959411

Family Applications (1)

Application Number Title Priority Date Filing Date
GB42907/76A Expired GB1560406A (en) 1975-10-17 1976-10-15 Solid solutions of ergot alkaholids in polymers

Country Status (28)

Country Link
JP (1) JPS5854122B2 (es)
AT (1) AT362510B (es)
AU (1) AU508628B2 (es)
BE (1) BE847368A (es)
CA (1) CA1079641A (es)
CH (1) CH643737A5 (es)
CS (1) CS199647B2 (es)
DE (1) DE2546577B2 (es)
DK (1) DK146194C (es)
ES (1) ES452420A1 (es)
FI (1) FI762875A (es)
FR (1) FR2327764A1 (es)
GB (1) GB1560406A (es)
GR (1) GR61268B (es)
HK (1) HK3183A (es)
HU (1) HU172533B (es)
IE (1) IE43778B1 (es)
IL (1) IL50686A (es)
MY (1) MY8400063A (es)
NL (1) NL184558C (es)
NO (1) NO144468C (es)
NZ (1) NZ182341A (es)
PH (1) PH14513A (es)
PT (1) PT65719B (es)
SE (1) SE430379B (es)
SG (1) SG63082G (es)
SU (1) SU1165223A3 (es)
ZA (1) ZA766166B (es)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450877A (en) * 1977-11-03 1984-05-29 Hoechst Aktiengesellschaft Pharmaceutical preparations in solid unit dosage form
GB2160100A (en) * 1984-06-14 1985-12-18 Sandoz Ltd Galenical retard formulations
US4992278A (en) * 1987-01-14 1991-02-12 Ciba-Geigy Corporation Therapeutic system for sparingly soluble active ingredients
WO1999032118A1 (en) * 1997-12-22 1999-07-01 Schering Corporation Molecular dispersion composition with enhanced bioavailability
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
WO2005000273A1 (en) * 2003-06-27 2005-01-06 Bioprogress S.P.A. Composite product obtainable by cogrinding of a active principle with a copolymer n-vinyl-2-pyrrolidone/vinyl-acetate
US7070968B2 (en) 1994-02-04 2006-07-04 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411882A (en) 1978-12-21 1983-10-25 Sandoz Ltd. Galenical compositions
WO1980001242A1 (en) * 1978-12-21 1980-06-26 Sandoz Ag Galenical preparation
FR2454804B1 (fr) * 1979-04-26 1986-11-21 Sanofi Sa Medicament a base de dihydroergotoxine et son procede de preparation
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
FR2610827B1 (fr) * 1987-02-18 1991-09-13 Pf Medicament Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication
US5064656A (en) * 1989-11-14 1991-11-12 Dr. Gergely & Co. Uncoated pharmaceutical reaction tablet
DE4401646A1 (de) * 1994-01-21 1995-07-27 Krewel Werke Gmbh Optimal freisetzende Kava-Extrakte
US7771746B2 (en) 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
JP4965784B2 (ja) * 1999-12-03 2012-07-04 ポリケム・ソシエテ・アノニム バイオアベイラビリティの向上した麦角アルカロイドの徐放性医薬組成物の製造法及びその組成物
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450877A (en) * 1977-11-03 1984-05-29 Hoechst Aktiengesellschaft Pharmaceutical preparations in solid unit dosage form
GB2160100A (en) * 1984-06-14 1985-12-18 Sandoz Ltd Galenical retard formulations
US4992278A (en) * 1987-01-14 1991-02-12 Ciba-Geigy Corporation Therapeutic system for sparingly soluble active ingredients
US7070968B2 (en) 1994-02-04 2006-07-04 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
US7838512B2 (en) 1994-02-04 2010-11-23 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
WO1999032118A1 (en) * 1997-12-22 1999-07-01 Schering Corporation Molecular dispersion composition with enhanced bioavailability
AU761994B2 (en) * 1997-12-22 2003-06-12 Merck Sharp & Dohme Corp. Molecular dispersion composition with enhanced bioavailability
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
AU761994C (en) * 1997-12-22 2004-01-08 Merck Sharp & Dohme Corp. Molecular dispersion composition with enhanced bioavailability
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
WO2005000273A1 (en) * 2003-06-27 2005-01-06 Bioprogress S.P.A. Composite product obtainable by cogrinding of a active principle with a copolymer n-vinyl-2-pyrrolidone/vinyl-acetate

Also Published As

Publication number Publication date
FI762875A (es) 1977-04-18
PT65719A (fr) 1976-11-01
IE43778L (en) 1977-04-17
DK454176A (da) 1977-04-18
IL50686A (en) 1979-05-31
AT362510B (de) 1981-05-25
IL50686A0 (en) 1976-12-31
DE2546577B2 (de) 1981-04-02
AU1875476A (en) 1978-04-20
NZ182341A (en) 1978-09-20
DK146194B (da) 1983-07-25
IE43778B1 (en) 1981-05-20
ATA767976A (de) 1980-10-15
NL184558C (nl) 1989-09-01
CS199647B2 (en) 1980-07-31
NL184558B (nl) 1989-04-03
ZA766166B (en) 1978-05-30
AU508628B2 (en) 1980-03-27
ES452420A1 (es) 1978-04-16
JPS5251014A (en) 1977-04-23
CA1079641A (en) 1980-06-17
MY8400063A (en) 1984-12-31
NL7611295A (nl) 1977-04-19
JPS5854122B2 (ja) 1983-12-02
DE2546577A1 (de) 1977-04-21
DK146194C (da) 1984-01-02
FR2327764A1 (fr) 1977-05-13
NO144468C (no) 1981-09-09
SE7611189L (sv) 1977-04-18
SU1165223A3 (ru) 1985-06-30
SE430379B (sv) 1983-11-14
CH643737A5 (en) 1984-06-29
BE847368A (fr) 1977-04-15
GR61268B (en) 1978-10-17
NO144468B (no) 1981-06-01
PH14513A (en) 1981-08-24
FR2327764B1 (es) 1979-03-02
PT65719B (fr) 1978-06-12
NO763446L (es) 1977-04-19
SG63082G (en) 1983-09-09
HU172533B (hu) 1978-09-28
HK3183A (en) 1983-01-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PCNP Patent ceased through non-payment of renewal fee