GB1520247A - Pelletised medicament formulations - Google Patents
Pelletised medicament formulationsInfo
- Publication number
- GB1520247A GB1520247A GB35334/74A GB3533474A GB1520247A GB 1520247 A GB1520247 A GB 1520247A GB 35334/74 A GB35334/74 A GB 35334/74A GB 3533474 A GB3533474 A GB 3533474A GB 1520247 A GB1520247 A GB 1520247A
- Authority
- GB
- United Kingdom
- Prior art keywords
- agglomerates
- microns
- medicament
- pelletised
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical compound O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 239000012298 atmosphere Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000004040 coloring Methods 0.000 abstract 1
- 229960000265 cromoglicic acid Drugs 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229960001317 isoprenaline Drugs 0.000 abstract 1
- 238000009877 rendering Methods 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Otolaryngology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB35334/74A GB1520247A (en) | 1974-08-10 | 1974-08-10 | Pelletised medicament formulations |
IE1645/75A IE41586B1 (en) | 1974-08-10 | 1975-07-23 | Pelletised medicament formulations |
ZA00754765A ZA754765B (en) | 1974-08-10 | 1975-07-23 | Pharmaceutical composition in pellet form |
CY1049A CY1049A (en) | 1974-08-10 | 1975-07-24 | Pelletised medicament formulations |
IL47829A IL47829A (en) | 1974-08-10 | 1975-07-28 | Medicament in pellet form and its preparation |
CA232,477A CA1072569A (en) | 1974-08-10 | 1975-07-29 | Pellet form medicament |
NLAANVRAGE7509080,A NL177980C (nl) | 1974-08-10 | 1975-07-30 | Werkwijze voor het vervaardigen van een vast, inhaleerbaar geneesmiddel-preparaat, alsmede houder, die een dergelijk preparaat bevat. |
AR259849A AR210997A1 (es) | 1974-08-10 | 1975-07-31 | Metodo para la produccion del medicamento cromoglicato disodico en forma de granulos. |
BE158922A BE832097A (fr) | 1974-08-10 | 1975-08-04 | Medicaments en granules friables propres a l'inhalation |
FI752232A FI65547C (fi) | 1974-08-10 | 1975-08-06 | Foerfarande foer framstaellning av foer inhalering avsedda mjuka dinatriumkromoglykatpelletar |
DE2535258A DE2535258C2 (de) | 1974-08-10 | 1975-08-07 | Inhalierbares Medikament in Pelletform |
BR7505055*A BR7505055A (pt) | 1974-08-10 | 1975-08-07 | Medicamento em pelota e processo de sua manufatura |
FR7524631A FR2282259A1 (fr) | 1974-08-10 | 1975-08-07 | Medicament sous forme de grains friables |
DK360875A DK145654C (da) | 1974-08-10 | 1975-08-08 | Inhaleringspraeparat til anvendelse i en insufflator og fremgangsmaade til fremstilling deraf |
SE7508967A SE440595B (sv) | 1974-08-10 | 1975-08-08 | Forfaraande for framstellning av mjuka dinatriumkromoglykatpelletkulor for inhalering |
ES440139A ES440139A1 (es) | 1974-08-10 | 1975-08-08 | Metodo mejorado para la fabricacion de un medicamento de inhalacion en forma de granulos blandos. |
LU73182A LU73182A1 (enrdf_load_stackoverflow) | 1974-08-10 | 1975-08-08 | |
NO752786A NO146660C (no) | 1974-08-10 | 1975-08-08 | Fremgangsmaate til fremstilling av myke dinatriumchromoglykatpellets. |
HU75FI596A HU175594B (hu) | 1974-08-10 | 1975-08-08 | Sposob poluchenija farmacevticheskikh preparatov formulirovannykh v forme piljulej |
JP50096732A JPS5910326B2 (ja) | 1974-08-10 | 1975-08-11 | 軟質ペレツト状薬物の製造方法 |
AU83859/75A AU492916B2 (en) | 1974-08-10 | 1975-08-11 | Medicament in soft pellet form |
DE19772702504 DE2702504A1 (de) | 1974-08-10 | 1977-01-21 | Arzneimittel in weicher tabletten- oder koernerform |
KE3034A KE3034A (en) | 1974-08-10 | 1980-03-10 | Pelletised medicament formulations |
HK177/80A HK17780A (en) | 1974-08-10 | 1980-04-03 | Pelletised medicament formulations |
MY34/81A MY8100034A (en) | 1974-08-10 | 1981-12-30 | Pelletised medicament formulations |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB35334/74A GB1520247A (en) | 1974-08-10 | 1974-08-10 | Pelletised medicament formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1520247A true GB1520247A (en) | 1978-08-02 |
Family
ID=10376566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB35334/74A Expired GB1520247A (en) | 1974-08-10 | 1974-08-10 | Pelletised medicament formulations |
Country Status (21)
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0398631A1 (en) * | 1989-05-17 | 1990-11-22 | FISONS plc | Pharmaceutical composition |
GB2237510A (en) * | 1989-11-04 | 1991-05-08 | Danbiosyst Uk | Small particle drug compositions for nasal administration |
US5198221A (en) * | 1989-05-17 | 1993-03-30 | Fisons Plc | Pharmaceutical composition |
US5551489A (en) * | 1993-10-01 | 1996-09-03 | Astra Aktiebolag | Agglomeration of finely divided powders |
US6102036A (en) * | 1994-04-12 | 2000-08-15 | Smoke-Stop | Breath activated inhaler |
US6284287B1 (en) | 1994-07-16 | 2001-09-04 | Asta Medica Ag | Particulate formulation for administration by inhalation |
US6371171B1 (en) | 1993-10-01 | 2002-04-16 | Astra Aktiebolag | Agglomeration of finely divided powders |
US6436902B1 (en) | 1994-12-22 | 2002-08-20 | Astrazeneca Ab | Therapeutic preparations for inhalation |
US6495167B2 (en) | 1997-03-20 | 2002-12-17 | Schering Corporation | Preparation of powder agglomerates |
US6503537B2 (en) | 1997-03-20 | 2003-01-07 | Schering Corporation | Preparation of powder agglomerates |
US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
US6610653B1 (en) | 1994-06-23 | 2003-08-26 | Astrazeneca Ab | Therapeutic preparation for inhalation |
US6623760B1 (en) | 1999-01-28 | 2003-09-23 | Schering Corporation | Method of preparing particles for agglomeration |
US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
US6846801B1 (en) | 1993-06-24 | 2005-01-25 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
US6884794B2 (en) | 2000-04-17 | 2005-04-26 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets |
US6932962B1 (en) | 1994-12-22 | 2005-08-23 | Astrazeneca Ab | Aerosol drug formulations containing hydrofluoroalkanes and alkyl saccharides |
US7399528B2 (en) | 1999-07-16 | 2008-07-15 | Chiesi Farmaceutici S.P.A. | Powder particles with smooth surface for use in inhalation therapy |
EP2036544A1 (en) | 1997-03-20 | 2009-03-18 | Schering Corporation | Dosage form of powder agglomerates |
US8871274B2 (en) | 2000-04-17 | 2014-10-28 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2741202A1 (de) * | 1976-09-23 | 1978-03-30 | Fisons Ltd | Dinatriumcromoglycat mit besonderer massendichte |
JPS6034925B2 (ja) * | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
DE3636209A1 (de) * | 1986-10-24 | 1988-04-28 | Lentia Gmbh | Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates |
TWI225402B (en) | 1996-03-13 | 2004-12-21 | Biochemie Gmbh | Auxiliary-free agglomerates |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1812574A1 (de) * | 1968-12-04 | 1970-06-11 | Riedel De Haen Ag | Verfahren zur Herstellung biozider Granulate |
GB1381872A (en) * | 1971-06-22 | 1975-01-29 | Fisons Ltd | Pharmaceutical compositions for inhalation |
-
1974
- 1974-08-10 GB GB35334/74A patent/GB1520247A/en not_active Expired
-
1975
- 1975-07-23 ZA ZA00754765A patent/ZA754765B/xx unknown
- 1975-07-23 IE IE1645/75A patent/IE41586B1/en not_active IP Right Cessation
- 1975-07-24 CY CY1049A patent/CY1049A/xx unknown
- 1975-07-28 IL IL47829A patent/IL47829A/xx unknown
- 1975-07-29 CA CA232,477A patent/CA1072569A/en not_active Expired
- 1975-07-30 NL NLAANVRAGE7509080,A patent/NL177980C/xx not_active IP Right Cessation
- 1975-07-31 AR AR259849A patent/AR210997A1/es active
- 1975-08-04 BE BE158922A patent/BE832097A/xx not_active IP Right Cessation
- 1975-08-06 FI FI752232A patent/FI65547C/fi not_active IP Right Cessation
- 1975-08-07 BR BR7505055*A patent/BR7505055A/pt unknown
- 1975-08-07 FR FR7524631A patent/FR2282259A1/fr active Granted
- 1975-08-08 DK DK360875A patent/DK145654C/da not_active IP Right Cessation
- 1975-08-08 HU HU75FI596A patent/HU175594B/hu unknown
- 1975-08-08 LU LU73182A patent/LU73182A1/xx unknown
- 1975-08-08 NO NO752786A patent/NO146660C/no unknown
- 1975-08-08 SE SE7508967A patent/SE440595B/xx not_active IP Right Cessation
- 1975-08-11 JP JP50096732A patent/JPS5910326B2/ja not_active Expired
-
1980
- 1980-03-10 KE KE3034A patent/KE3034A/xx unknown
- 1980-04-03 HK HK177/80A patent/HK17780A/xx unknown
-
1981
- 1981-12-30 MY MY34/81A patent/MY8100034A/xx unknown
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5198221A (en) * | 1989-05-17 | 1993-03-30 | Fisons Plc | Pharmaceutical composition |
EP0398631A1 (en) * | 1989-05-17 | 1990-11-22 | FISONS plc | Pharmaceutical composition |
GB2237510A (en) * | 1989-11-04 | 1991-05-08 | Danbiosyst Uk | Small particle drug compositions for nasal administration |
GB2237510B (en) * | 1989-11-04 | 1993-09-15 | Danbiosyst Uk | Small particle drug compositions for nasal administration |
US6846801B1 (en) | 1993-06-24 | 2005-01-25 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
US5551489A (en) * | 1993-10-01 | 1996-09-03 | Astra Aktiebolag | Agglomeration of finely divided powders |
US6371171B1 (en) | 1993-10-01 | 2002-04-16 | Astra Aktiebolag | Agglomeration of finely divided powders |
US6102036A (en) * | 1994-04-12 | 2000-08-15 | Smoke-Stop | Breath activated inhaler |
US6610653B1 (en) | 1994-06-23 | 2003-08-26 | Astrazeneca Ab | Therapeutic preparation for inhalation |
US6284287B1 (en) | 1994-07-16 | 2001-09-04 | Asta Medica Ag | Particulate formulation for administration by inhalation |
US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
US6932962B1 (en) | 1994-12-22 | 2005-08-23 | Astrazeneca Ab | Aerosol drug formulations containing hydrofluoroalkanes and alkyl saccharides |
US6436902B1 (en) | 1994-12-22 | 2002-08-20 | Astrazeneca Ab | Therapeutic preparations for inhalation |
US6495167B2 (en) | 1997-03-20 | 2002-12-17 | Schering Corporation | Preparation of powder agglomerates |
US6503537B2 (en) | 1997-03-20 | 2003-01-07 | Schering Corporation | Preparation of powder agglomerates |
EP2036544A1 (en) | 1997-03-20 | 2009-03-18 | Schering Corporation | Dosage form of powder agglomerates |
US8173172B2 (en) | 1997-03-20 | 2012-05-08 | Schering Corporation | Preparation of powder agglomerates |
US6623760B1 (en) | 1999-01-28 | 2003-09-23 | Schering Corporation | Method of preparing particles for agglomeration |
US7399528B2 (en) | 1999-07-16 | 2008-07-15 | Chiesi Farmaceutici S.P.A. | Powder particles with smooth surface for use in inhalation therapy |
US6884794B2 (en) | 2000-04-17 | 2005-04-26 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets |
EP1719505A2 (en) | 2000-04-17 | 2006-11-08 | CHIESI FARMACEUTICI S.p.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard pellets |
US7223748B2 (en) | 2000-04-17 | 2007-05-29 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets |
EP2272508A2 (en) | 2000-04-17 | 2011-01-12 | Vectura Limited | Pharmaceutical Formulations for Dry Powder Inhalers |
US8871274B2 (en) | 2000-04-17 | 2014-10-28 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
US9566239B2 (en) | 2000-04-17 | 2017-02-14 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
PE20 | Patent expired after termination of 20 years |
Effective date: 19950723 |