GB1369259A - Acylxylidide local anaesthetics - Google Patents

Acylxylidide local anaesthetics

Info

Publication number
GB1369259A
GB1369259A GB5937771A GB5937771A GB1369259A GB 1369259 A GB1369259 A GB 1369259A GB 5937771 A GB5937771 A GB 5937771A GB 5937771 A GB5937771 A GB 5937771A GB 1369259 A GB1369259 A GB 1369259A
Authority
GB
United Kingdom
Prior art keywords
alkyl
reacting
pharmaceutically acceptable
formula
xylidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5937771A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra USA Inc
Original Assignee
Astra Pharmaceutical Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceutical Products Inc filed Critical Astra Pharmaceutical Products Inc
Publication of GB1369259A publication Critical patent/GB1369259A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38—Acyl halides
    • C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
    • C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
GB5937771A 1970-12-22 1971-12-21 Acylxylidide local anaesthetics Expired GB1369259A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10077770A 1970-12-22 1970-12-22
US00164022A US3812147A (en) 1970-12-22 1971-07-19 Acylxylidide local anaesthetics

Publications (1)

Publication Number Publication Date
GB1369259A true GB1369259A (en) 1974-10-23

Family

ID=26797539

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5937771A Expired GB1369259A (en) 1970-12-22 1971-12-21 Acylxylidide local anaesthetics

Country Status (23)

Country Link
US (1) US3812147A (no)
JP (1) JPS5644063B1 (no)
AR (1) AR193840A1 (no)
AT (1) AT319205B (no)
AU (1) AU468489B2 (no)
BE (1) BE776656A (no)
BR (1) BR7108466D0 (no)
CA (1) CA943966A (no)
DD (1) DD99779A5 (no)
DE (1) DE2162744C3 (no)
DK (1) DK139814B (no)
ES (2) ES398210A1 (no)
FI (1) FI55027C (no)
FR (1) FR2118985B1 (no)
GB (1) GB1369259A (no)
HU (1) HU163373B (no)
IE (1) IE35909B1 (no)
IT (1) IT1066334B (no)
NL (2) NL172149C (no)
NO (1) NO135934C (no)
PL (1) PL83097B1 (no)
SE (1) SE393374B (no)
SU (1) SU419023A3 (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009986A1 (en) * 1989-02-28 1990-09-07 Aktiebolaget Astra New local anaesthetic compounds and a process for their preparation

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237068A (en) * 1971-07-28 1980-12-02 Astra Pharmaceutical Products, Inc. Primary aminoacylanilides
US3966934A (en) * 1971-12-08 1976-06-29 Astra Pharmaceutical Products, Inc. Synergistic local anesthetic compositions
US3957996A (en) * 1971-12-08 1976-05-18 Astra Pharmaceutical Products, Inc. Pharmaceutical local anesthetic compositions
US3975443A (en) * 1972-06-06 1976-08-17 Allen & Hanburys Limited 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
JPS598269B2 (ja) * 1975-08-22 1984-02-23 萬有製薬株式会社 オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ
JPS57176939A (en) * 1981-04-03 1982-10-30 Goodrich Co B F Improved synthesis of hindered amine stabilizer for high polymer materials
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
EP2101819B1 (en) 2006-11-20 2013-01-09 President and Fellows of Harvard College Methods, compositions, and kits for treating pain and pruritis
CA3027255C (en) 2009-07-10 2022-06-21 The General Hospital Corporation Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
JP6833811B2 (ja) 2015-08-03 2021-02-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 荷電イオンチャネル遮断薬及び使用方法
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US11377422B2 (en) 2019-03-11 2022-07-05 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
AU2020237474A1 (en) 2019-03-11 2021-09-30 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CA3129089A1 (en) 2019-03-11 2020-09-17 Bridget Mccarthy Cole Ester substituted ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
KR20220123381A (ko) 2019-11-06 2022-09-06 녹시온 테라퓨틱스 인코포레이티드 하전된 이온 채널 차단제 및 사용 방법
EP4118070A4 (en) 2020-03-11 2024-04-10 Nocion Therapeutics, Inc. CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124837A (en) * 1966-06-03 1968-08-21 Wyeth John & Brother Ltd Substituted anilides

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009986A1 (en) * 1989-02-28 1990-09-07 Aktiebolaget Astra New local anaesthetic compounds and a process for their preparation
GR900100108A (el) * 1989-02-28 1991-06-28 Astra Ab Νεες ενωσεις τοπικης αναισθησιας και μεθοδος για την παρασκευη τους.

Also Published As

Publication number Publication date
FI55027B (fi) 1979-01-31
DE2162744B2 (de) 1981-07-02
ES398210A1 (es) 1975-03-16
CA943966A (en) 1974-03-19
ES425626A1 (es) 1976-06-16
AT319205B (de) 1974-12-10
JPS5644063B1 (no) 1981-10-16
FI55027C (fi) 1979-05-10
IT1066334B (it) 1985-03-04
DD99779A5 (no) 1973-08-20
AU3709971A (en) 1973-06-28
DK139814C (no) 1979-10-01
SE393374B (sv) 1977-05-09
NO135934B (no) 1977-03-21
AU468489B2 (en) 1976-01-15
BR7108466D0 (pt) 1973-06-14
BE776656A (fr) 1972-06-14
NL7117644A (no) 1972-06-26
SU419023A3 (ru) 1974-03-05
IE35909B1 (en) 1976-06-23
NL172149C (nl) 1983-07-18
FR2118985A1 (no) 1972-08-04
IE35909L (en) 1972-06-22
DE2162744C3 (de) 1982-04-15
NO135934C (no) 1977-06-29
PL83097B1 (no) 1975-12-31
DK139814B (da) 1979-04-23
AR193840A1 (es) 1973-05-31
US3812147A (en) 1974-05-21
NL172149B (nl) 1983-02-16
FR2118985B1 (no) 1975-12-26
HU163373B (no) 1973-08-28
NL8204126A (nl) 1983-02-01
DE2162744A1 (de) 1972-07-06

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years