GB1160151A - Therapeutically Active Metal Chelates of Proteins - Google Patents
Therapeutically Active Metal Chelates of ProteinsInfo
- Publication number
- GB1160151A GB1160151A GB4497766A GB4497766A GB1160151A GB 1160151 A GB1160151 A GB 1160151A GB 4497766 A GB4497766 A GB 4497766A GB 4497766 A GB4497766 A GB 4497766A GB 1160151 A GB1160151 A GB 1160151A
- Authority
- GB
- United Kingdom
- Prior art keywords
- chelate
- metal
- chelates
- proteins
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052751 metal Inorganic materials 0.000 title abstract 7
- 239000002184 metal Substances 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 235000018102 proteins Nutrition 0.000 abstract 6
- 239000013522 chelant Substances 0.000 abstract 4
- 235000001014 amino acid Nutrition 0.000 abstract 3
- 229940024606 amino acid Drugs 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 235000018417 cysteine Nutrition 0.000 abstract 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 2
- 150000002739 metals Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002674 ointment Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- 239000004475 Arginine Substances 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 102000006395 Globulins Human genes 0.000 abstract 1
- 108010044091 Globulins Proteins 0.000 abstract 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 210000001557 animal structure Anatomy 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N aspartic acid group Chemical group N[C@@H](CC(=O)O)C(=O)O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- 229910052796 boron Inorganic materials 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 229910052804 chromium Inorganic materials 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 230000016396 cytokine production Effects 0.000 abstract 1
- 238000004925 denaturation Methods 0.000 abstract 1
- 230000036425 denaturation Effects 0.000 abstract 1
- 238000001962 electrophoresis Methods 0.000 abstract 1
- 239000002662 enteric coated tablet Substances 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- 229910052745 lead Inorganic materials 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 229910052748 manganese Inorganic materials 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000001742 protein purification Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052710 silicon Inorganic materials 0.000 abstract 1
- 239000010703 silicon Substances 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 235000013311 vegetables Nutrition 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4717—Plasma globulins, lactoglobulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49404865A | 1965-10-08 | 1965-10-08 | |
| US57645466A | 1966-08-31 | 1966-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1160151A true GB1160151A (en) | 1969-07-30 |
Family
ID=27051278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4497766A Expired GB1160151A (en) | 1965-10-08 | 1966-10-07 | Therapeutically Active Metal Chelates of Proteins |
Country Status (11)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3624251A (en) * | 1970-01-16 | 1971-11-30 | Diagnostic Data Inc | Orgotein purification process by heating above 65{20 {0 c. |
| US3687927A (en) * | 1971-06-07 | 1972-08-29 | Diagnostic Data Inc | Orgotein isolation process employing single ion exchange resin having both acidic and basic groups |
| CN114656653A (zh) * | 2022-03-22 | 2022-06-24 | 中国农业大学 | 一种金属离子诱导副肌球蛋白水凝胶的制备及解离方法 |
| CN116831287A (zh) * | 2023-06-21 | 2023-10-03 | 中国食品发酵工业研究院有限公司 | 一种豌豆蛋白-姜黄素纳米颗粒及其制备方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52163241U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1976-06-04 | 1977-12-10 | ||
| HU185420B (en) * | 1981-04-27 | 1985-02-28 | Erdoekemiai Erdoegazdasagi Veg | Process for the production of ammonium-complexes of natural proteins and bioactive coating and retaining substance compositions of plant protection containing such compounds |
| IT1150213B (it) * | 1982-03-02 | 1986-12-10 | Italfarmaco Spa | Derivati di ferro biodisponibile esenti da gastrolesivita',procentimento di preparazione e relative composizioni farmaceutiche |
-
1966
- 1966-09-21 IL IL2655166A patent/IL26551A/xx unknown
- 1966-10-03 ES ES0331853A patent/ES331853A1/es not_active Expired
- 1966-10-05 BE BE687828D patent/BE687828A/xx not_active IP Right Cessation
- 1966-10-06 CH CH1447066A patent/CH575433A5/de not_active IP Right Cessation
- 1966-10-06 DE DE1966B0089232 patent/DE1617332C3/de not_active Expired
- 1966-10-07 NL NL6614177A patent/NL152756B/xx not_active IP Right Cessation
- 1966-10-07 GB GB4497766A patent/GB1160151A/en not_active Expired
- 1966-10-07 SE SE1359766A patent/SE362012B/xx unknown
- 1966-10-07 DK DK522766A patent/DK122434B/da unknown
- 1966-10-07 FR FR79235A patent/FR6237M/fr not_active Expired
- 1966-10-08 JP JP41066148A patent/JPS494929B1/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3624251A (en) * | 1970-01-16 | 1971-11-30 | Diagnostic Data Inc | Orgotein purification process by heating above 65{20 {0 c. |
| US3687927A (en) * | 1971-06-07 | 1972-08-29 | Diagnostic Data Inc | Orgotein isolation process employing single ion exchange resin having both acidic and basic groups |
| CN114656653A (zh) * | 2022-03-22 | 2022-06-24 | 中国农业大学 | 一种金属离子诱导副肌球蛋白水凝胶的制备及解离方法 |
| CN114656653B (zh) * | 2022-03-22 | 2023-08-04 | 中国农业大学 | 一种金属离子诱导副肌球蛋白水凝胶的制备及解离方法 |
| CN116831287A (zh) * | 2023-06-21 | 2023-10-03 | 中国食品发酵工业研究院有限公司 | 一种豌豆蛋白-姜黄素纳米颗粒及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE687828A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-04-05 |
| NL152756B (nl) | 1977-04-15 |
| DK122434B (da) | 1972-03-06 |
| IL26551A (en) | 1970-06-17 |
| ES331853A1 (es) | 1967-12-01 |
| SE362012B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-11-26 |
| CH575433A5 (en) | 1976-05-14 |
| DE1617332C3 (de) | 1979-09-13 |
| NL6614177A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-04-10 |
| JPS494929B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-02-04 |
| DE1617332A1 (de) | 1972-01-27 |
| DE1617332B2 (de) | 1979-01-11 |
| FR6237M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1968-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed |