GB1035005A - Local anesthetic preparations and process of making same - Google Patents
Local anesthetic preparations and process of making sameInfo
- Publication number
- GB1035005A GB1035005A GB8735/64A GB873564A GB1035005A GB 1035005 A GB1035005 A GB 1035005A GB 8735/64 A GB8735/64 A GB 8735/64A GB 873564 A GB873564 A GB 873564A GB 1035005 A GB1035005 A GB 1035005A
- Authority
- GB
- United Kingdom
- Prior art keywords
- anaesthetic
- carbon dioxide
- base
- solutions
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003589 local anesthetic agent Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 8
- 230000003444 anaesthetic effect Effects 0.000 abstract 7
- 239000001569 carbon dioxide Substances 0.000 abstract 4
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 2
- 150000005827 chlorofluoro hydrocarbons Chemical class 0.000 abstract 2
- 229960004194 lidocaine Drugs 0.000 abstract 2
- 239000003380 propellant Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Substances [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 abstract 1
- 239000000159 acid neutralizing agent Substances 0.000 abstract 1
- 229940124326 anaesthetic agent Drugs 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000005323 carbonate salts Chemical class 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 235000015110 jellies Nutrition 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 229960002409 mepivacaine Drugs 0.000 abstract 1
- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- -1 n-butyl-amino Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US177172A US3136691A (en) | 1962-03-05 | 1962-03-05 | Aqueous solution of local anesthetic maintained under pressure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1035005A true GB1035005A (en) | 1966-07-06 |
Family
ID=22647491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8735/64A Expired GB1035005A (en) | 1962-03-05 | 1963-03-05 | Local anesthetic preparations and process of making same |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3136691A (enrdf_load_stackoverflow) |
| CH (1) | CH465767A (enrdf_load_stackoverflow) |
| DE (1) | DE1220967B (enrdf_load_stackoverflow) |
| DK (1) | DK109053C (enrdf_load_stackoverflow) |
| GB (1) | GB1035005A (enrdf_load_stackoverflow) |
| SE (1) | SE315689B (enrdf_load_stackoverflow) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4811692B1 (enrdf_load_stackoverflow) * | 1967-07-07 | 1973-04-14 | ||
| US3940483A (en) * | 1971-02-05 | 1976-02-24 | E. R. Squibb & Sons, Inc. | Antibiotic compositions and method |
| US4218477A (en) * | 1971-07-28 | 1980-08-19 | Astra Pharmaceutical Products, Inc. | Primary aminoacylanilides, methods of making the same and use as antiarrhythmic drugs |
| US4935225A (en) * | 1987-09-11 | 1990-06-19 | Curtis John P | Appetite suppresant dentifrice |
| US5331012A (en) * | 1990-07-30 | 1994-07-19 | Riddick Kenneth B | Topical pharmaceutical preparation for fever blisters and other viral infections and method of use |
| US20050123484A1 (en) * | 2003-10-02 | 2005-06-09 | Collegium Pharmaceutical, Inc. | Non-flammable topical anesthetic liquid aerosols |
| US20060188449A1 (en) * | 2003-10-03 | 2006-08-24 | Jane Hirsh | Topical aerosol foams |
| US8652443B2 (en) * | 2008-02-14 | 2014-02-18 | Precision Dermatology, Inc. | Foamable microemulsion compositions for topical administration |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR981029A (fr) * | 1949-02-17 | 1951-05-21 | Procédé de pulvérisation fine d'un liquide | |
| US2953284A (en) * | 1957-12-06 | 1960-09-20 | Aerosol Tech Inc | Pressurized dispenser |
-
1962
- 1962-03-05 US US177172A patent/US3136691A/en not_active Expired - Lifetime
-
1963
- 1963-03-04 DE DEA42495A patent/DE1220967B/de active Pending
- 1963-03-05 GB GB8735/64A patent/GB1035005A/en not_active Expired
- 1963-03-05 SE SE2383/63A patent/SE315689B/xx unknown
- 1963-03-05 DK DK99763AA patent/DK109053C/da active
- 1963-03-05 CH CH278663A patent/CH465767A/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1220967B (de) | 1966-07-14 |
| DK109053C (da) | 1968-03-11 |
| US3136691A (en) | 1964-06-09 |
| SE315689B (enrdf_load_stackoverflow) | 1969-10-06 |
| CH465767A (de) | 1968-11-30 |
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