GB0823554D0 - Process for the preparation of optically active compounds using transfer hydrogenation - Google Patents

Process for the preparation of optically active compounds using transfer hydrogenation

Info

Publication number
GB0823554D0
GB0823554D0 GBGB0823554.1A GB0823554A GB0823554D0 GB 0823554 D0 GB0823554 D0 GB 0823554D0 GB 0823554 A GB0823554 A GB 0823554A GB 0823554 D0 GB0823554 D0 GB 0823554D0
Authority
GB
United Kingdom
Prior art keywords
preparation
optically active
active compounds
transfer hydrogenation
hydrogenation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0823554.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40344210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0823554(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB0823554.1A priority Critical patent/GB0823554D0/en
Publication of GB0823554D0 publication Critical patent/GB0823554D0/en
Priority to US12/653,748 priority patent/US8415508B2/en
Priority to ARP090105061A priority patent/AR075496A1/es
Priority to PCT/EP2009/067821 priority patent/WO2010072798A1/en
Priority to SG2011042108A priority patent/SG172052A1/en
Priority to KR1020117017258A priority patent/KR20110098964A/ko
Priority to CA2748349A priority patent/CA2748349A1/en
Priority to AU2009331493A priority patent/AU2009331493B2/en
Priority to NZ593493A priority patent/NZ593493A/xx
Priority to EP09799106A priority patent/EP2382172A1/en
Priority to BRPI0923394A priority patent/BRPI0923394A2/pt
Priority to MA34036A priority patent/MA32983B1/fr
Priority to MX2011006918A priority patent/MX2011006918A/es
Priority to TW098144595A priority patent/TW201035028A/zh
Priority to CN2009801523437A priority patent/CN102264672A/zh
Priority to MYPI20112891 priority patent/MY151103A/en
Priority to JP2011542822A priority patent/JP2012513966A/ja
Priority to TN2011000290A priority patent/TN2011000290A1/fr
Priority to IL213520A priority patent/IL213520A0/en
Priority to CL2011001563A priority patent/CL2011001563A1/es
Priority to CO11081447A priority patent/CO6382153A2/es
Priority to EC2011011221A priority patent/ECSP11011221A/es
Priority to US13/705,884 priority patent/US8637713B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • C07C303/30—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reactions not involving the formation of esterified sulfo groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
    • C07C39/11—Alkylated hydroxy benzenes containing also acyclically bound hydroxy groups, e.g. saligenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
GBGB0823554.1A 2008-12-24 2008-12-24 Process for the preparation of optically active compounds using transfer hydrogenation Ceased GB0823554D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GBGB0823554.1A GB0823554D0 (en) 2008-12-24 2008-12-24 Process for the preparation of optically active compounds using transfer hydrogenation
US12/653,748 US8415508B2 (en) 2008-12-24 2009-12-17 Process for the preparation of optically active compounds using transfer hydrogenation
ARP090105061A AR075496A1 (es) 2008-12-24 2009-12-22 Proceso para la preparacion de compuestos opticamente activos usando hidrogenacion de transferencia y uso de los mismos
MYPI20112891 MY151103A (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
JP2011542822A JP2012513966A (ja) 2008-12-24 2009-12-23 水素移動反応を使用する光学活性化合物の調製の方法
EP09799106A EP2382172A1 (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
CN2009801523437A CN102264672A (zh) 2008-12-24 2009-12-23 使用转移氢化制备旋光化合物的方法
KR1020117017258A KR20110098964A (ko) 2008-12-24 2009-12-23 수소화 전이반응을 사용한 광학 활성 화합물의 제조 방법
CA2748349A CA2748349A1 (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
AU2009331493A AU2009331493B2 (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
NZ593493A NZ593493A (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
PCT/EP2009/067821 WO2010072798A1 (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
BRPI0923394A BRPI0923394A2 (pt) 2008-12-24 2009-12-23 processo para preparação de compostos opticamente ativos usando hidrogenação de tranferência.
MA34036A MA32983B1 (fr) 2008-12-24 2009-12-23 Procede de preparation de composes optiquement actifs par hydrogenation par transfert
MX2011006918A MX2011006918A (es) 2008-12-24 2009-12-23 Proceso para la preparacion de compuestos opticamente activos usando hidrogenacion de transferencia.
TW098144595A TW201035028A (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
SG2011042108A SG172052A1 (en) 2008-12-24 2009-12-23 Process for the preparation of optically active compounds using transfer hydrogenation
TN2011000290A TN2011000290A1 (en) 2008-12-24 2011-06-09 Process for the preparation of optically active compounds using transfer hydrogenation
IL213520A IL213520A0 (en) 2008-12-24 2011-06-13 Process for the preparation of optically active compounds using transfer hydrogenation
CL2011001563A CL2011001563A1 (es) 2008-12-24 2011-06-23 Proceso para preparar compuestos opticamente activos derivados de fenol por medio de hidrogenacion de transferencia sobre una hidroxifenona, siendo los compuestos formados utiles en la preparacion de compuestos tales como rivastigmina.
CO11081447A CO6382153A2 (es) 2008-12-24 2011-06-29 Proceso para la preparacion de compuestos opticamente activos usando hidrogenacion de transferencia
EC2011011221A ECSP11011221A (es) 2008-12-24 2011-07-22 Proceso para la preparación de compuestos ópticamente activos usando hidrogenación de transferencia
US13/705,884 US8637713B2 (en) 2008-12-24 2012-12-05 Process for preparation of optically active compounds using transfer hydrogenation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0823554.1A GB0823554D0 (en) 2008-12-24 2008-12-24 Process for the preparation of optically active compounds using transfer hydrogenation

Publications (1)

Publication Number Publication Date
GB0823554D0 true GB0823554D0 (en) 2009-01-28

Family

ID=40344210

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0823554.1A Ceased GB0823554D0 (en) 2008-12-24 2008-12-24 Process for the preparation of optically active compounds using transfer hydrogenation

Country Status (22)

Country Link
US (2) US8415508B2 (https=)
EP (1) EP2382172A1 (https=)
JP (1) JP2012513966A (https=)
KR (1) KR20110098964A (https=)
CN (1) CN102264672A (https=)
AR (1) AR075496A1 (https=)
AU (1) AU2009331493B2 (https=)
BR (1) BRPI0923394A2 (https=)
CA (1) CA2748349A1 (https=)
CL (1) CL2011001563A1 (https=)
CO (1) CO6382153A2 (https=)
EC (1) ECSP11011221A (https=)
GB (1) GB0823554D0 (https=)
IL (1) IL213520A0 (https=)
MA (1) MA32983B1 (https=)
MX (1) MX2011006918A (https=)
MY (1) MY151103A (https=)
NZ (1) NZ593493A (https=)
SG (1) SG172052A1 (https=)
TN (1) TN2011000290A1 (https=)
TW (1) TW201035028A (https=)
WO (1) WO2010072798A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103193600B (zh) * 2012-01-07 2016-04-06 浙江九洲药物科技有限公司 卡巴拉汀中间体的制备方法
WO2014200094A1 (ja) * 2013-06-14 2014-12-18 日産化学工業株式会社 光学活性アルコール化合物の製造方法
CN103980270A (zh) * 2014-05-19 2014-08-13 埃斯特维华义制药有限公司 一种（r）-3-奎宁醇的制备方法
CN108752322A (zh) * 2018-09-12 2018-11-06 广州新民培林医药科技有限公司 一种新型Tepotinib衍生物和制备方法及其在抗肿瘤药物中的应用
CN109809967B (zh) * 2019-03-04 2022-03-18 陕西师范大学 一种合成手性醇的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201906B (en) 1987-03-04 1991-01-28 Sandoz Ag Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them
US4996235A (en) * 1987-11-25 1991-02-26 Eli Lilly And Company 3,4-diphenylbutanamines
JPH0899940A (ja) * 1994-09-30 1996-04-16 Kanegafuchi Chem Ind Co Ltd 光学活性な１−（３，４−ジメトキシフェニル）−２−アミノプロパンの製造法
GB9706321D0 (en) 1997-03-26 1997-05-14 Zeneca Ltd Catalytic hydrogenation
JP3938651B2 (ja) * 2000-04-13 2007-06-27 セントラル硝子株式会社 光学活性α−メチル−ビス−３、５−（トリフルオロメチル）ベンジルアミンの製造方法
WO2002051781A1 (fr) 2000-12-25 2002-07-04 Ajinomoto Co., Inc. Procede permettant de preparer un compose d'halohydrine optiquement actif
ATE414053T1 (de) * 2003-07-08 2008-11-15 Unilever Nv Verfahren zur herstellung einer kosmetisch aktiven verbindung
GB0329284D0 (en) 2003-12-18 2004-01-21 Avecia Ltd Process
KR101085804B1 (ko) 2004-03-29 2011-11-22 간토 가가꾸 가부시키가이샤 광학 활성 알코올의 제법
US6939981B1 (en) * 2004-06-25 2005-09-06 Eastman Chemical Company Ruthenium complexes of phosphine-aminophosphine ligands
RU2393148C2 (ru) * 2004-11-08 2010-06-27 Эмкюр Фармасьютикалз Лимитед Способ получения (s)-3-[(1-диметиламино)этил]-фенил-n-этил-n-метил-карбамата
WO2006137167A1 (ja) 2005-06-20 2006-12-28 Kanto Kagaku Kabushiki Kaisha スルホナート触媒及びそれを利用したアルコール化合物の製法
TWI389709B (zh) 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
WO2007147897A1 (de) 2006-06-23 2007-12-27 Basf Se Verfahren zur herstellung von optisch aktiven 2-halogen-1-phenylethanol-derivaten und folgeprodukten davon
US20110105693A1 (en) 2008-05-01 2011-05-05 Kanata Chemical Technologies Inc. Cationic transition-metal arene catalysts

Also Published As

Publication number Publication date
US8637713B2 (en) 2014-01-28
US20100168229A1 (en) 2010-07-01
MA32983B1 (fr) 2012-01-02
ECSP11011221A (es) 2011-08-31
NZ593493A (en) 2013-03-28
CN102264672A (zh) 2011-11-30
BRPI0923394A2 (pt) 2016-01-12
TW201035028A (en) 2010-10-01
CL2011001563A1 (es) 2012-01-13
WO2010072798A1 (en) 2010-07-01
MY151103A (en) 2014-04-15
EP2382172A1 (en) 2011-11-02
US8415508B2 (en) 2013-04-09
IL213520A0 (en) 2011-07-31
SG172052A1 (en) 2011-07-28
AR075496A1 (es) 2011-04-06
KR20110098964A (ko) 2011-09-02
US20130096337A1 (en) 2013-04-18
MX2011006918A (es) 2011-07-29
JP2012513966A (ja) 2012-06-21
CO6382153A2 (es) 2012-02-15
TN2011000290A1 (en) 2012-12-17
AU2009331493B2 (en) 2013-03-07
AU2009331493A1 (en) 2011-07-07
CA2748349A1 (en) 2010-07-01

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)