GB0700133D0 - Human cytomegalovirus neutralising antibodies and use thereof - Google Patents
Human cytomegalovirus neutralising antibodies and use thereofInfo
- Publication number
- GB0700133D0 GB0700133D0 GBGB0700133.2A GB0700133A GB0700133D0 GB 0700133 D0 GB0700133 D0 GB 0700133D0 GB 0700133 A GB0700133 A GB 0700133A GB 0700133 D0 GB0700133 D0 GB 0700133D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- human cytomegalovirus
- neutralising antibodies
- cytomegalovirus neutralising
- antibodies
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—DNA viruses
- C07K16/085—Orthoherpesviridae (F), e.g. pseudorabies virus or Epstein-Barr virus
- C07K16/089—Cytomegalovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (49)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0700133.2A GB0700133D0 (en) | 2007-01-04 | 2007-01-04 | Human cytomegalovirus neutralising antibodies and use thereof |
| EP14188865.1A EP2860189A3 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| CA2673755A CA2673755C (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| BRPI0806185-8A BRPI0806185A2 (pt) | 2007-01-04 | 2008-01-03 | anticorpo neutralizador de alta potência, fragmento de um anticorpo, molécula de ácido nucléico, vetor, célula, clone de célula b imortalizado, epìtopo, polipeptìdio imunogênico, método para produção de anticorpos, composição farmacêutica, uso de um primeiro anticorpo ou fragmento, composição ou uso, método para tratamento de um sujeito, kit para diagnóstico de infecção por hcmv, método para preparação de uma célula recombinante, método para produção de anticorpos, método de detecção de polipeptìdios e epìtopo que se liga especificamente a um anticorpo |
| RU2009129403/10A RU2469045C2 (ru) | 2007-01-04 | 2008-01-03 | Антитела, нейтрализующие цитомегаловирус человека, и их применение |
| JP2009544477A JP5710123B2 (ja) | 2007-01-04 | 2008-01-03 | ヒトサイトメガロウイルス中和抗体およびその使用 |
| KR1020147021517A KR101659306B1 (ko) | 2007-01-04 | 2008-01-03 | 인간 사이토메갈로바이러스 중화 항체 및 이의 용도 |
| SI200831025T SI2118140T1 (sl) | 2007-01-04 | 2008-01-03 | Protitelesa, ki nevtralizirajo humani citomegalovirus, in njihova uporaba |
| MYPI2013003538A MY161200A (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| ES12156048.6T ES2526907T3 (es) | 2007-01-04 | 2008-01-03 | Anticuerpos neutralizantes de citomegalovirus humano y su uso |
| MYPI20092825 MY150709A (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| HK10104864.3A HK1139158B (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| HRP20130877AT HRP20130877T1 (hr) | 2007-01-04 | 2008-01-03 | Antitijela koja neutraliziraju humani citomegalovirus i njihova primjena |
| EP08737590.3A EP2118140B1 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| MX2009007320A MX2009007320A (es) | 2007-01-04 | 2008-01-03 | Anticuerpos neutralizantes del citomegalovirus humano y su uso. |
| PT121560486T PT2487187E (pt) | 2007-01-04 | 2008-01-03 | Anticorpos neutralizantes de citomegalovírus humano e sua utilização |
| KR1020097016334A KR101541927B1 (ko) | 2007-01-04 | 2008-01-03 | 인간 사이토메갈로바이러스 중화 항체 및 이의 용도 |
| PCT/IB2008/001111 WO2008084410A2 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| US11/969,104 US7955599B2 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralizing antibodies and use thereof |
| PL08737590T PL2118140T3 (pl) | 2007-01-04 | 2008-01-03 | Przeciwciała neutralizujące ludzki cytomegalowirus i ich zastosowanie |
| SG2013042544A SG192399A1 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| SG2011097805A SG177943A1 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| NZ578844A NZ578844A (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| CN2008800071531A CN101657467B (zh) | 2007-01-04 | 2008-01-03 | 人类巨细胞病毒中和抗体及其用途 |
| EP12156048.6A EP2487187B1 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| DK08737590.3T DK2118140T3 (da) | 2007-01-04 | 2008-01-03 | Humancytomegalovirus-neutraliserende antistoffer og anvendelse deraf |
| PT87375903T PT2118140E (pt) | 2007-01-04 | 2008-01-03 | Anticorpos neutralizantes de citomegalovírus humano e utilização destes |
| ES08737590T ES2426987T3 (es) | 2007-01-04 | 2008-01-03 | Anticuerpos neutralizantes de citomegalovirus humano y su uso |
| SG2013042486A SG191635A1 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| UAA200908229A UA100682C2 (ru) | 2007-01-04 | 2008-01-03 | АНТИТЕЛО, КОТОРОЕ НЕЙТРАЛИЗУЕТ ЧЕЛОВЕЧЕСКИЙ ЦИТОМЕГАЛОВИРУС (hCMV), И ЕГО ПРИМЕНЕНИЕ |
| AU2008204258A AU2008204258B2 (en) | 2007-01-04 | 2008-01-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| US12/174,568 US7947274B2 (en) | 2007-01-04 | 2008-07-16 | Human cytomegalovirus neutralising antibodies and use thereof |
| IL199585A IL199585A (en) | 2007-01-04 | 2009-06-25 | Antibodies that neutralize and utilize human cytomegalovirus |
| GT200900188A GT200900188A (es) | 2007-01-04 | 2009-07-01 | Anticuerpos neutralizantes del citomegalovirus humano y su uso. |
| TNP2009000285A TN2009000285A1 (en) | 2007-01-04 | 2009-07-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| EC2009009547A ECSP099547A (es) | 2007-01-04 | 2009-07-29 | Anticuerpos neutralizantes del citomegalovirus humano y su uso |
| CR10961A CR10961A (es) | 2007-01-04 | 2009-07-31 | Anticuerpos neutralizantes del citomegalovirus humano y su uso |
| ZA200905408A ZA200905408B (en) | 2007-01-04 | 2009-08-03 | Human cytomegalovirus neutralising antibodies and use thereof |
| MA32141A MA31225B1 (fr) | 2007-01-04 | 2009-08-04 | Anticorps neutralisants des cytomegalovirus humains et leur utilisation |
| CO09081236A CO6220862A2 (es) | 2007-01-04 | 2009-08-04 | Anticuerpos neutralizantes de citomegalovirus humano y su uso |
| US13/087,814 US8298538B2 (en) | 2007-01-04 | 2011-04-15 | Human cytomegalovirus neutralising antibodies and use thereof |
| US13/092,364 US8309089B2 (en) | 2007-01-04 | 2011-04-22 | Human cytomegalovirus neutralising antibodies and use thereof |
| US13/618,264 US9217028B2 (en) | 2007-01-04 | 2012-09-14 | Human cytomegalovirus neutralising antibodies and use thereof |
| US13/619,305 US8545848B2 (en) | 2007-01-04 | 2012-09-14 | Human cytomegalovirus neutralising antibodies and use thereof |
| HK13101783.4A HK1174344B (en) | 2007-01-04 | 2013-02-08 | Human cytomegalovirus neutralising antibodies and use thereof |
| CY20131100726T CY1114271T1 (el) | 2007-01-04 | 2013-08-26 | Αντισωματα εξουδετερωσης, ανθρωπινου κυτταρομεγαλοϊου και χρηση αυτων |
| US14/041,799 US9149524B2 (en) | 2007-01-04 | 2013-09-30 | Human cytomegalovirus neutralising antibodies and use thereof |
| JP2014043126A JP2014141501A (ja) | 2007-01-04 | 2014-03-05 | ヒトサイトメガロウイルス中和抗体およびその使用 |
| US14/938,438 US9611316B2 (en) | 2007-01-04 | 2015-11-11 | Human cytomegalovirus neutralising antibodies and use thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0700133.2A GB0700133D0 (en) | 2007-01-04 | 2007-01-04 | Human cytomegalovirus neutralising antibodies and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0700133D0 true GB0700133D0 (en) | 2007-02-14 |
Family
ID=37801734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0700133.2A Ceased GB0700133D0 (en) | 2007-01-04 | 2007-01-04 | Human cytomegalovirus neutralising antibodies and use thereof |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | US7955599B2 (enExample) |
| EP (3) | EP2487187B1 (enExample) |
| JP (2) | JP5710123B2 (enExample) |
| KR (2) | KR101659306B1 (enExample) |
| CN (1) | CN101657467B (enExample) |
| AU (1) | AU2008204258B2 (enExample) |
| BR (1) | BRPI0806185A2 (enExample) |
| CA (1) | CA2673755C (enExample) |
| CO (1) | CO6220862A2 (enExample) |
| CR (1) | CR10961A (enExample) |
| CY (1) | CY1114271T1 (enExample) |
| DK (1) | DK2118140T3 (enExample) |
| EC (1) | ECSP099547A (enExample) |
| ES (2) | ES2526907T3 (enExample) |
| GB (1) | GB0700133D0 (enExample) |
| GT (1) | GT200900188A (enExample) |
| HR (1) | HRP20130877T1 (enExample) |
| IL (1) | IL199585A (enExample) |
| MA (1) | MA31225B1 (enExample) |
| MX (1) | MX2009007320A (enExample) |
| MY (2) | MY150709A (enExample) |
| NZ (1) | NZ578844A (enExample) |
| PL (1) | PL2118140T3 (enExample) |
| PT (2) | PT2487187E (enExample) |
| RU (1) | RU2469045C2 (enExample) |
| SG (3) | SG191635A1 (enExample) |
| SI (1) | SI2118140T1 (enExample) |
| TN (1) | TN2009000285A1 (enExample) |
| UA (1) | UA100682C2 (enExample) |
| WO (1) | WO2008084410A2 (enExample) |
| ZA (1) | ZA200905408B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3031469B1 (en) * | 2006-06-07 | 2023-08-23 | The Trustees Of Princeton University | Cytomegalovirus surface protein complex for use in vaccines and as a drug target |
| US7947274B2 (en) | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
| GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
| US8435510B2 (en) | 2007-08-08 | 2013-05-07 | Sutter West Bay Hospitals | Platelet derived growth factor receptor supports cytomegalovirus infectivity |
| US8124093B2 (en) | 2008-07-16 | 2012-02-28 | Institute For Research In Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
| AU2012203417B2 (en) * | 2008-07-16 | 2014-07-10 | Institute For Research In Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
| JP5475774B2 (ja) * | 2008-07-16 | 2014-04-16 | インスティテュート フォー リサーチ イン バイオメディシン | ヒトサイトメガロウイルス中和抗体およびその使用 |
| ES2662519T3 (es) * | 2008-07-25 | 2018-04-06 | Institute For Research In Biomedicine | Anticuerpos neutralizantes contra el virus de la gripe A y usos de estos |
| US8871207B2 (en) | 2008-07-25 | 2014-10-28 | Humabs, LLC | Neutralizing anti-influenza A virus antibodies and uses thereof |
| DK2420572T3 (en) | 2009-04-01 | 2015-06-15 | Evec Inc | MONOCLONAL ANTIBODY THAT CAN BIND TO SPECIFIC discontinuous EPITOPE, OCCURRING IN AD 1 REGION OF HUMAN cytomegalovirus GB-glycoprotein AND ANTIBODY-binding fragment thereof. |
| NZ600974A (en) * | 2009-12-23 | 2014-08-29 | 4Antibody Ag | Binding members for human cytomegalovirus |
| CA2839420C (en) | 2010-06-16 | 2023-06-13 | Lawrence M. Kauvar | High affinity human antibodies to human cytomegalovirus (cmv) gb protein |
| CA2841551C (en) | 2011-07-18 | 2020-07-28 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
| BR112014024023A2 (pt) | 2012-03-28 | 2017-07-18 | Genentech Inc | anticorpos idiotípicos anti-hcmv e usos dos mesmos |
| WO2014099908A1 (en) * | 2012-12-17 | 2014-06-26 | Genentech, Inc. | Methods for inhibiting viral infection in transplant patients |
| JP6535675B2 (ja) | 2013-10-02 | 2019-06-26 | メディミューン,エルエルシー | 抗a型インフルエンザ抗体の中和及びその使用 |
| CN113563462B (zh) | 2014-07-15 | 2024-08-13 | 免疫医疗有限责任公司 | 中和抗乙型流感抗体及其用途 |
| US20160069643A1 (en) * | 2014-09-06 | 2016-03-10 | Philip Lyren | Weapon Targeting System |
| MX389708B (es) | 2015-06-01 | 2025-03-20 | Medimmune Llc | Neutralizacion de moleculas de union anti-influenza y usos de las mismas. |
| US11136407B2 (en) * | 2016-01-08 | 2021-10-05 | Aimm Therapeutics B.V. | Therapeutic anti-CD9 antibody |
| SG11201805001UA (en) | 2016-01-13 | 2018-07-30 | Medimmune Llc | Method of treating influenza a |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| CA3019588A1 (en) | 2016-04-20 | 2017-10-26 | Merck Sharp & Dohme Corp. | Cmv neutralizing antigen binding proteins |
| CN112004826B (zh) * | 2018-02-05 | 2024-06-14 | 自由大学基金会 | 反向激动性抗us28抗体 |
| CN109580944A (zh) * | 2018-12-07 | 2019-04-05 | 潍坊医学院 | 一种人巨细胞病毒检测试纸及其制造方法 |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| CN109738631A (zh) * | 2019-01-21 | 2019-05-10 | 潍坊医学院 | 一种人巨细胞病毒IgM抗体检测试纸的制备方法 |
| CN112898414B (zh) * | 2019-12-04 | 2024-05-10 | 珠海泰诺麦博制药股份有限公司 | 抗人巨细胞病毒抗体及其用途 |
| US11857622B2 (en) | 2020-06-21 | 2024-01-02 | Pfizer Inc. | Human cytomegalovirus GB polypeptide |
| CN118459574B (zh) * | 2022-10-21 | 2025-06-17 | 珠海泰诺麦博制药股份有限公司 | 抗人巨细胞病毒抗体及其用途 |
Family Cites Families (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1061943A (en) | 1964-09-10 | 1967-03-15 | Carter S Ink Co | Marking composition |
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3766162A (en) | 1971-08-24 | 1973-10-16 | Hoffmann La Roche | Barbituric acid antigens and antibodies specific therefor |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4294817A (en) | 1977-11-25 | 1981-10-13 | International Diagnostic Technology, Inc. | Method of fluoro immunoassay |
| US4233402A (en) | 1978-04-05 | 1980-11-11 | Syva Company | Reagents and method employing channeling |
| US4313927A (en) | 1979-10-19 | 1982-02-02 | Ames-Yissum Ltd. | Immunoassay method for detecting viral antibodies in whole blood samples |
| US4334016A (en) | 1980-06-19 | 1982-06-08 | The Wistar Institute Of Anatomy And Biology | Human osteogenic sarcoma cell line and use thereof for immunofluorescent antibody test |
| JPS5896026A (ja) | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
| US4609546A (en) | 1982-06-24 | 1986-09-02 | Japan Chemical Research Co., Ltd. | Long-acting composition |
| FR2543570B1 (fr) | 1983-03-31 | 1985-08-09 | Pasteur Institut | Anticorps monoclonaux anticytomegalovirus humains, hybridomes secreteurs de ces anticorps et polypeptides porteurs d'un determinant antigenique sequentiel de cytomegalovirus humains |
| US4617379A (en) | 1983-06-14 | 1986-10-14 | Miles Laboratories, Inc. | High titer cytomegalovirus immune serum globulin |
| GB8404368D0 (en) | 1984-02-20 | 1984-03-28 | Cogent Ltd | Monoclonal antibodies to human cytomegalovirus |
| US6100064A (en) | 1984-04-06 | 2000-08-08 | Chiron Corporation | Secreted viral proteins useful for vaccines and diagnostics |
| FR2563630B1 (fr) | 1984-04-27 | 1988-02-19 | Pasteur Institut | Anticorps monoclonaux anticytomegalovirus et procedes pour le diagnostic in vitro des infections par les cytomegalovirus humains et d'une proteine-kinase inductible par les cytomegalovirus et susceptible d'etre reconnue par les susdits anticorps monoclonaux |
| US4783399A (en) | 1984-05-04 | 1988-11-08 | Scripps Clinic And Research Foundation | Diagnostic system for the detection of cytomegalovirus |
| US4743562A (en) | 1984-08-21 | 1988-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Purified human cytomegalovirus protein |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| EP0198086B1 (en) | 1984-09-28 | 1991-01-16 | Teijin Limited | Mouse human hybridoma producing antivirus human antibody, process for its preparation, and antivirus human monoclonal antibody |
| US4808518A (en) | 1985-02-11 | 1989-02-28 | University Of Tennessee Research Corporation | Recovery of cytomegalovirus antigen and use thereof in an assay |
| US4804627A (en) | 1985-05-09 | 1989-02-14 | Sloan-Kettering Institute For Cancer Research | Method for cloning lymphoblastoid cells |
| US4766106A (en) | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| EP0248909B1 (en) | 1985-12-06 | 1994-08-17 | Teijin Limited | Anticytomegaloviral human monoclonal antibody and process for its preparation |
| US4831175A (en) | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US5126130A (en) | 1986-11-24 | 1992-06-30 | The Childrens Hospital Incorporated | Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a |
| US5153311A (en) | 1986-11-24 | 1992-10-06 | The Children's Hospital, Incorporated | Immunogenic glycoproteins of human cytomegalovirus gCII |
| LU86752A1 (fr) | 1987-01-30 | 1988-08-23 | Univ Bruxelles | Procede de production d'anticorps monoclonaux humains(igg)anticytomegalovirus et anticorps monoclonaux ainsi obtenus |
| NZ226694A (en) | 1987-10-28 | 1994-04-27 | Oncogen | Human immunoglobulin produced by recombinant dna techniques |
| US5180813A (en) | 1989-03-24 | 1993-01-19 | University Of Iowa Research Foundation | Early envelope glycoprotein of human cytomegalovirus (hmcv) and monoclonal antibodies to the glycoproteins |
| US5194654A (en) | 1989-11-22 | 1993-03-16 | Vical, Inc. | Lipid derivatives of phosphonoacids for liposomal incorporation and method of use |
| WO1991004277A1 (en) | 1989-09-14 | 1991-04-04 | Children's Biomedical Research Institute | Monoclonal antibodies specific to cytomegalovirus glycoprotein |
| WO1991005876A1 (en) | 1989-10-20 | 1991-05-02 | Children's Biomedical Research Institute | Human cytomegalovirus-specific monoclonal antibody cocktail |
| GB9008223D0 (en) | 1990-04-11 | 1990-06-13 | Royal Free Hosp School Med | Improvements relating to the detection of viruses |
| DE4035174A1 (de) | 1990-11-06 | 1992-05-07 | Biotest Ag | Verfahren zur bestimmung von proteinen in koerperfluessigkeiten und mittel zur durchfuehrung des verfahrens |
| US5997878A (en) | 1991-03-07 | 1999-12-07 | Connaught Laboratories | Recombinant poxvirus-cytomegalovirus, compositions and uses |
| JPH053794A (ja) * | 1991-06-26 | 1993-01-14 | Green Cross Corp:The | 抗サイトメガロウイルスヒトモノクローナル抗体およびその産生細胞 |
| DE4128684A1 (de) | 1991-08-29 | 1993-03-04 | Behringwerke Ag | Hcmv-spezifische peptide, mittel dazu und ihre verwendung |
| ES2125248T3 (es) | 1992-04-10 | 1999-03-01 | Thomas Totterman | Metodo de deteccion de una infeccion cmv. |
| SE9201281L (sv) | 1992-04-23 | 1993-10-24 | Bioinvent Int Ab | Nya humana monoklonala antikroppar och förfarande för framställning därav |
| JPH05260961A (ja) * | 1992-05-21 | 1993-10-12 | Teijin Ltd | サイトメガロウイルスに対するヒト・モノクローナル抗体を産生するハイブリドーマ |
| GB9221654D0 (en) * | 1992-10-15 | 1992-11-25 | Scotgen Ltd | Recombinant human anti-cytomegalovirus antibodies |
| AU681115B2 (en) | 1993-01-21 | 1997-08-21 | Erna Moller | Prevention and treatment of cytomegalovirus using aminopeptidase |
| JPH08506325A (ja) | 1993-01-28 | 1996-07-09 | サンド ファーマスーティカル コーポレーション | サイトメガロウイルスに対するヒトモノクローナル抗体 |
| US5750106A (en) * | 1993-01-28 | 1998-05-12 | Novartis Ag | Human monoclonal antibodies to cytomegalovirus |
| AU6777594A (en) | 1993-04-30 | 1994-11-21 | Scripps Research Institute, The | Human monoclonal antibodies to human cytomegalovirus, and methods therefor |
| US5595721A (en) | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| EP0702083A3 (de) | 1994-07-26 | 1997-01-15 | Biotest Ag | Polypeptide und Fusionsproteine bestehend aus dem UL 57 Leserahmen bzw. dem C-terminalen Bereich des Tegumentproteins pp150 aus HCMV, entsprechende Oligonucleotide und Nachweis reagentien |
| US5783383A (en) | 1995-05-23 | 1998-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of detecting cytomegalovirus (CMV) |
| US6019980A (en) | 1995-06-07 | 2000-02-01 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| US5800981A (en) | 1996-02-22 | 1998-09-01 | University Of Limburg | Human cytomegalovirus antigen and its use |
| DE69716305T2 (de) | 1996-07-12 | 2003-06-26 | Organon Teknika B.V., Boxtel | Peptidereagenz zum nachweis von humanem cytomegalovirus (cmv) |
| CA2263316A1 (en) | 1996-08-14 | 1998-02-19 | Klara Berencsi | Methods and compositions for preventing or retarding the development of atherosclerotic lesions |
| WO1998033892A1 (en) | 1997-01-30 | 1998-08-06 | Cedars-Sinai Medical Center | Establishment of hhv-8+ lymphoma cell line, virus produced, antibody, diagnostic method and kit for detecting hhv-8 infection |
| US6183752B1 (en) | 1997-02-05 | 2001-02-06 | Pasteur Merieux Serums Et Vaccins | Restenosis/atherosclerosis diagnosis, prophylaxis and therapy |
| AU8063798A (en) | 1997-06-19 | 1999-01-04 | Regents Of The University Of California, The | Secretory immunoglobulin produced by single cells and methods for making and using same |
| EP0996730A1 (en) | 1997-07-18 | 2000-05-03 | Connaught Laboratories Limited | Nucleic acid vaccines encoding g protein of respiratory syncytial virus |
| US20030180257A1 (en) | 1997-11-14 | 2003-09-25 | Mark Parrington | Alphavirus vectors for paramyxovirus vaccines |
| DE19756214C1 (de) | 1997-12-17 | 1999-02-25 | Biotest Ag | Polypeptide mit Aminosäuresequenzen aus dem N-terminalen Bereich von gp116 und deren Verwendung bei der Diagnostik, Prophylaxe und Therapie |
| IL138033A0 (en) | 1998-03-12 | 2001-10-31 | Genentech Inc | Method of preventing the death of retinal neurons and treating ocular diseases |
| EP1091763B1 (de) | 1998-06-29 | 2003-09-17 | Wolfgang Bergter | Antivirale und antiretrovirale radioimmunpharmaka auf der basis von alpha- und beta-strahlern |
| RU2133472C1 (ru) | 1998-09-16 | 1999-07-20 | Унитарное государственное Московское предприятие по производству бактерийных препаратов | Способ диагностики активной стадии цитомегаловирусной инфекции человека |
| MY133346A (en) | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
| US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
| ITMI20012160A1 (it) | 2001-10-18 | 2003-04-18 | Edoardo Marchisio | Sistema immunoenzimatico per la caratterizzazione antigenica dell'infezione attiva da cytomegalovirus e cmv confirmation test |
| US6828113B2 (en) | 2002-03-21 | 2004-12-07 | Cornell Research Foundation, Inc. | IgM antibodies to the 70 kDa heat shock protein as a marker for cytomegalovirus infection |
| IL164326A0 (en) | 2002-04-01 | 2005-12-18 | Agensys Inc | Nucleic acid and corresponding protein entitled 238p1b2 and pharmaceutical compositions containing the same |
| RU2239453C2 (ru) * | 2002-12-03 | 2004-11-10 | Федеральное государственное унитарное предприятие " Научно-производственное объединение по медицинским иммунобиологическим препаратам " Микроген" | Препарат иммуноглобулина человека против цитомегаловируса и способ его получения |
| EP1597280B2 (en) | 2003-02-26 | 2016-08-24 | Institute for Research in Biomedicine | Monoclonal antibody production by ebv transformation of b cells |
| US20040228842A1 (en) | 2003-02-27 | 2004-11-18 | Shan Lu | Compositions and methods for cytomegalovirus treatment |
| US20060216302A1 (en) | 2003-02-28 | 2006-09-28 | Robert Root-Bernstein | Immunological markers |
| JP5160887B2 (ja) | 2004-06-21 | 2013-03-13 | メダレックス インコーポレイテッド | インターフェロンアルファレセプター1抗体及びその使用法 |
| BE1016287A6 (nl) | 2004-07-14 | 2006-07-04 | Picanol Nv | Gaapvormingsonderdeel voor een weefmachine en weefmachine. |
| US7976845B2 (en) | 2004-11-29 | 2011-07-12 | The Council Of The Queensland Institute Of Medical Research | Human cytomegalovirus immunotherapy |
| DE602005027258D1 (de) | 2005-03-14 | 2011-05-12 | Us Gov Health & Human Serv | Humane monoklonale antikörper gegen hendra- und nipah-viren |
| KR101508945B1 (ko) | 2005-12-16 | 2015-04-08 | 리보박스 바이오테크놀로지즈 에스아 | 불멸화 항체분비 세포를 수득하는 방법 |
| JPWO2007094423A1 (ja) | 2006-02-15 | 2009-07-09 | 株式会社イーベック | ヒトサイトメガロウイルスに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| MX2008014722A (es) | 2006-05-19 | 2011-04-15 | Teva Pharma | Proteinas de fusion, usos de las mismas y procesos para producir las mismas. |
| EP3031469B1 (en) | 2006-06-07 | 2023-08-23 | The Trustees Of Princeton University | Cytomegalovirus surface protein complex for use in vaccines and as a drug target |
| ES2363992T3 (es) | 2006-12-15 | 2011-08-22 | Ribovax Biotechnologies Sa | Anticuerpos frente a citomegalovirus humano (cmvh). |
| US7947274B2 (en) * | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
| GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
| WO2008120203A2 (en) | 2007-03-29 | 2008-10-09 | Technion Research & Development Foundation Ltd. | Antibodies and their uses for diagnosis and treatment of cytomegalovirus infection and associated diseases |
| US20080248042A1 (en) | 2007-04-05 | 2008-10-09 | Irccs Centro Di Riferimento Oncologico Di Aviano, | Monoclonal antibody cross-reactive against infective agent causing a B-cell expansion and IgG-Fc |
| EP2190876A1 (en) | 2007-08-22 | 2010-06-02 | Ribovax Biotechnologies SA | Antibodies against human cytomegalovirus (hcmv) |
| US7763261B2 (en) | 2007-12-19 | 2010-07-27 | Dcb-Usa Llc | Anti-human cytomegalovirus antibodies |
| JP5475774B2 (ja) | 2008-07-16 | 2014-04-16 | インスティテュート フォー リサーチ イン バイオメディシン | ヒトサイトメガロウイルス中和抗体およびその使用 |
| US8124093B2 (en) | 2008-07-16 | 2012-02-28 | Institute For Research In Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
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