GB0309009D0 - Quinazoline derivatives - Google Patents

Quinazoline derivatives

Info

Publication number
GB0309009D0
GB0309009D0 GBGB0309009.9A GB0309009A GB0309009D0 GB 0309009 D0 GB0309009 D0 GB 0309009D0 GB 0309009 A GB0309009 A GB 0309009A GB 0309009 D0 GB0309009 D0 GB 0309009D0
Authority
GB
United Kingdom
Prior art keywords
quinazoline derivatives
effect
tyrxosine
quinazsoline
animnal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0309009.9A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Priority to GBGB0309009.9A priority Critical patent/GB0309009D0/en
Publication of GB0309009D0 publication Critical patent/GB0309009D0/en
Priority to KR1020057020096A priority patent/KR20060006821A/ko
Priority to JP2006506155A priority patent/JP2006524218A/ja
Priority to PCT/GB2004/001713 priority patent/WO2004093880A1/en
Priority to AU2004231349A priority patent/AU2004231349A1/en
Priority to MXPA05011332A priority patent/MXPA05011332A/es
Priority to EP04728367A priority patent/EP1631292B1/en
Priority to CNB2004800170469A priority patent/CN100406453C/zh
Priority to ES04728367T priority patent/ES2329576T3/es
Priority to NZ543015A priority patent/NZ543015A/en
Priority to AT04728367T priority patent/ATE438402T1/de
Priority to US10/554,202 priority patent/US20070149546A1/en
Priority to HK06107909.9A priority patent/HK1087632B/en
Priority to CA002526897A priority patent/CA2526897A1/en
Priority to BRPI0409633-9A priority patent/BRPI0409633A/pt
Priority to DE602004022404T priority patent/DE602004022404D1/de
Priority to ZA200508525A priority patent/ZA200508525B/en
Priority to NO20054856A priority patent/NO20054856L/no
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GBGB0309009.9A 2003-04-22 2003-04-22 Quinazoline derivatives Ceased GB0309009D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB0309009.9A GB0309009D0 (en) 2003-04-22 2003-04-22 Quinazoline derivatives
DE602004022404T DE602004022404D1 (de) 2003-04-22 2004-04-20 4-anilino-chinazolin-derivate als proliferationshemmende mittel
ES04728367T ES2329576T3 (es) 2003-04-22 2004-04-20 Derivados de 4-anilino-quinazolina como agentes antiproliferativos.
AT04728367T ATE438402T1 (de) 2003-04-22 2004-04-20 4-anilino-chinazolin-derivate als proliferationshemmende mittel
PCT/GB2004/001713 WO2004093880A1 (en) 2003-04-22 2004-04-20 4-anilino-quinazoline derivatives as antiproliferative agents
AU2004231349A AU2004231349A1 (en) 2003-04-22 2004-04-20 4-anilino-quinazoline derivatives as antiproliferative agents
MXPA05011332A MXPA05011332A (es) 2003-04-22 2004-04-20 Derivados de 4-anilino-quinazolina como agentes antiproliferativos.
EP04728367A EP1631292B1 (en) 2003-04-22 2004-04-20 4-anilino-quinazoline derivatives as antiproliferative agents
CNB2004800170469A CN100406453C (zh) 2003-04-22 2004-04-20 抗增殖药4-苯胺基-喹唑啉衍生物
KR1020057020096A KR20060006821A (ko) 2003-04-22 2004-04-20 항증식제로서의 4-아닐리노-퀴나졸린 유도체
NZ543015A NZ543015A (en) 2003-04-22 2004-04-20 4-Anilino-quinazoline derivatives for producing antiproliferative effect by inhibiting erbB2 receptor tyrosine kinase
JP2006506155A JP2006524218A (ja) 2003-04-22 2004-04-20 増殖抑制薬としての４−アニリノキナゾリン誘導体
US10/554,202 US20070149546A1 (en) 2003-04-22 2004-04-20 4-Anilino-quinazoline derivatives as antiproliferative agents
HK06107909.9A HK1087632B (en) 2003-04-22 2004-04-20 4-anilino-quinazoline derivatives as antiproliferative agents
CA002526897A CA2526897A1 (en) 2003-04-22 2004-04-20 4-anilino-quinazoline derivatives as antiproliferative agents
BRPI0409633-9A BRPI0409633A (pt) 2003-04-22 2004-04-20 derivado de quinazolina, composição farmacêutica, e processo para a preparação do derivado de quinazolina
NO20054856A NO20054856L (no) 2003-04-22 2005-10-20 4-anilino-kinazolinderivater som antiproliferative midler
ZA200508525A ZA200508525B (en) 2003-04-22 2005-10-20 4-Anilino-quinazoline derivatives as antiproliferative agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0309009.9A GB0309009D0 (en) 2003-04-22 2003-04-22 Quinazoline derivatives

Publications (1)

Publication Number Publication Date
GB0309009D0 true GB0309009D0 (en) 2003-05-28

Family

ID=9957022

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0309009.9A Ceased GB0309009D0 (en) 2003-04-22 2003-04-22 Quinazoline derivatives

Country Status (17)

Country Link
US (1) US20070149546A1 (cg-RX-API-DMAC7.html)
EP (1) EP1631292B1 (cg-RX-API-DMAC7.html)
JP (1) JP2006524218A (cg-RX-API-DMAC7.html)
KR (1) KR20060006821A (cg-RX-API-DMAC7.html)
CN (1) CN100406453C (cg-RX-API-DMAC7.html)
AT (1) ATE438402T1 (cg-RX-API-DMAC7.html)
AU (1) AU2004231349A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0409633A (cg-RX-API-DMAC7.html)
CA (1) CA2526897A1 (cg-RX-API-DMAC7.html)
DE (1) DE602004022404D1 (cg-RX-API-DMAC7.html)
ES (1) ES2329576T3 (cg-RX-API-DMAC7.html)
GB (1) GB0309009D0 (cg-RX-API-DMAC7.html)
MX (1) MXPA05011332A (cg-RX-API-DMAC7.html)
NO (1) NO20054856L (cg-RX-API-DMAC7.html)
NZ (1) NZ543015A (cg-RX-API-DMAC7.html)
WO (1) WO2004093880A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200508525B (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115260164A (zh) * 2021-05-01 2022-11-01 杭州星鳌生物科技有限公司 新型4(3h)-喹唑啉酮类似物的制备方法、结构组成及其在抗肿瘤药物中的应用

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US6924285B2 (en) 2002-03-30 2005-08-02 Boehringer Ingelheim Pharma Gmbh & Co. Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
US20070021429A1 (en) * 2003-04-09 2007-01-25 Yves St-Denis Condensed n-heterocyclic compounds and their use as crf receptor antagonists
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JP2007501854A (ja) * 2003-05-27 2007-02-01 ファイザー・プロダクツ・インク 受容体型チロシンキナーゼ阻害薬としてのキナゾリン類およびピリド［３，４−ｄ］ピリミジン類
GB0321648D0 (en) * 2003-09-16 2003-10-15 Astrazeneca Ab Quinazoline derivatives
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US6924285B2 (en) * 2002-03-30 2005-08-02 Boehringer Ingelheim Pharma Gmbh & Co. Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
GB0309850D0 (en) * 2003-04-30 2003-06-04 Astrazeneca Ab Quinazoline derivatives
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EP1664028A1 (en) * 2003-09-16 2006-06-07 AstraZeneca AB Quinazoline derivatives as tyrosine kinase inhibitors
GB0321648D0 (en) * 2003-09-16 2003-10-15 Astrazeneca Ab Quinazoline derivatives
BRPI0414489A8 (pt) * 2003-09-16 2019-01-15 Astrazeneca Ab derivado de quinazolina, composição farmacêutica, uso de um derivado de quinazolina, e, processo para a preparação de um derivado de quinazolina
ATE353888T1 (de) * 2003-09-19 2007-03-15 Astrazeneca Ab Chinazolinderivate
CA2540008A1 (en) * 2003-09-25 2005-04-07 Astrazeneca Ab Quinazoline derivatives
GB0322409D0 (en) * 2003-09-25 2003-10-29 Astrazeneca Ab Quinazoline derivatives
GB0326459D0 (en) * 2003-11-13 2003-12-17 Astrazeneca Ab Quinazoline derivatives
WO2005075439A1 (en) * 2004-02-03 2005-08-18 Astrazeneca Ab Quinazoline derivatives
CN1993349A (zh) * 2004-06-04 2007-07-04 阿斯利康(瑞典)有限公司 作为erbb受体酪氨酸激酶的喹唑啉衍生物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115260164A (zh) * 2021-05-01 2022-11-01 杭州星鳌生物科技有限公司 新型4(3h)-喹唑啉酮类似物的制备方法、结构组成及其在抗肿瘤药物中的应用
CN115260164B (zh) * 2021-05-01 2024-03-26 杭州星鳌生物科技有限公司 新型4(3h)-喹唑啉酮类似物的制备方法、结构组成及其在抗肿瘤药物中的应用

Also Published As

Publication number Publication date
CN100406453C (zh) 2008-07-30
WO2004093880A1 (en) 2004-11-04
ZA200508525B (en) 2007-04-25
KR20060006821A (ko) 2006-01-19
HK1087632A1 (en) 2006-10-20
CN1809360A (zh) 2006-07-26
MXPA05011332A (es) 2005-11-28
NO20054856L (no) 2005-11-21
ES2329576T3 (es) 2009-11-27
CA2526897A1 (en) 2004-11-04
BRPI0409633A (pt) 2006-04-25
EP1631292B1 (en) 2009-08-05
NO20054856D0 (no) 2005-10-20
NZ543015A (en) 2008-01-31
ATE438402T1 (de) 2009-08-15
EP1631292A1 (en) 2006-03-08
AU2004231349A1 (en) 2004-11-04
DE602004022404D1 (de) 2009-09-17
US20070149546A1 (en) 2007-06-28
JP2006524218A (ja) 2006-10-26

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