FR3054137B1 - Dispositif medical implantable d’injection locoregionale - Google Patents

Dispositif medical implantable d’injection locoregionale Download PDF

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Publication number
FR3054137B1
FR3054137B1 FR1656954A FR1656954A FR3054137B1 FR 3054137 B1 FR3054137 B1 FR 3054137B1 FR 1656954 A FR1656954 A FR 1656954A FR 1656954 A FR1656954 A FR 1656954A FR 3054137 B1 FR3054137 B1 FR 3054137B1
Authority
FR
France
Prior art keywords
cover
microfluidic chip
medical device
implantable medical
parenchyma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1656954A
Other languages
English (en)
Other versions
FR3054137A1 (fr
Inventor
Brice Calvignac
Jean-Christophe Gimel
Laurent Lemaire
Florence Franconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite dAngers
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite dAngers
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1656954A priority Critical patent/FR3054137B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Universite dAngers, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Centre National de la Recherche Scientifique CNRS
Priority to EP17754405.3A priority patent/EP3487575A1/fr
Priority to US16/319,686 priority patent/US20210178136A1/en
Priority to CA3031316A priority patent/CA3031316A1/fr
Priority to CN201780045154.4A priority patent/CN109475729A/zh
Priority to JP2019502558A priority patent/JP7183145B2/ja
Priority to PCT/FR2017/052013 priority patent/WO2018015690A1/fr
Publication of FR3054137A1 publication Critical patent/FR3054137A1/fr
Application granted granted Critical
Publication of FR3054137B1 publication Critical patent/FR3054137B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un dispositif médical implantable (1) d'injection locorégionale dans la lumière d'un vaisseau sanguin ou dans un parenchyme comprenant une puce microfluidique (13) et un capot (14), dans lequel la puce microfluidique (13) comprend au moins un canal microfluidique (121) s'étendant depuis une première face de la puce microfluidique (13) jusqu'à une deuxième face de la puce microfluidique (13), le capot (14) comprend au moins deux micro-aiguilles creuses (11) faisant saillie depuis le capot (14), le capot (14) est fixé sur la deuxième face de la puce microfluidique (13) de sorte que le au moins un canal microfluidique (121) soit en connexion fluide avec les au moins deux micro-aiguilles creuses (11) ; et la longueur des au moins deux micro-aiguilles creuses (11) faisant saillie depuis le capot (14) est configuré de sorte que lorsque le capot (14) est implanté sur la paroi externe d'un vaisseau sanguin ou sur un parenchyme, l'extrémité des au moins deux microaiguilles creuses (11) pénètre la lumière du vaisseau sanguin ou dans le parenchyme.
FR1656954A 2016-07-21 2016-07-21 Dispositif medical implantable d’injection locoregionale Expired - Fee Related FR3054137B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR1656954A FR3054137B1 (fr) 2016-07-21 2016-07-21 Dispositif medical implantable d’injection locoregionale
US16/319,686 US20210178136A1 (en) 2016-07-21 2017-07-21 Implantable medical device for locoregional injection
CA3031316A CA3031316A1 (fr) 2016-07-21 2017-07-21 Dispositif medical implantable d'injection locoregionale
CN201780045154.4A CN109475729A (zh) 2016-07-21 2017-07-21 用于局部注射的可植入医疗装置
EP17754405.3A EP3487575A1 (fr) 2016-07-21 2017-07-21 Dispositif médical implantable d'injection locorégionale
JP2019502558A JP7183145B2 (ja) 2016-07-21 2017-07-21 局所領域注入のための植込み可能な医療装置
PCT/FR2017/052013 WO2018015690A1 (fr) 2016-07-21 2017-07-21 Dispositif médical implantable d'injection locorégionale

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1656954 2016-07-21
FR1656954A FR3054137B1 (fr) 2016-07-21 2016-07-21 Dispositif medical implantable d’injection locoregionale

Publications (2)

Publication Number Publication Date
FR3054137A1 FR3054137A1 (fr) 2018-01-26
FR3054137B1 true FR3054137B1 (fr) 2021-08-27

Family

ID=57396573

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1656954A Expired - Fee Related FR3054137B1 (fr) 2016-07-21 2016-07-21 Dispositif medical implantable d’injection locoregionale

Country Status (7)

Country Link
US (1) US20210178136A1 (fr)
EP (1) EP3487575A1 (fr)
JP (1) JP7183145B2 (fr)
CN (1) CN109475729A (fr)
CA (1) CA3031316A1 (fr)
FR (1) FR3054137B1 (fr)
WO (1) WO2018015690A1 (fr)

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5797898A (en) 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US7070590B1 (en) 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
CA2352974A1 (fr) * 1998-12-18 2000-06-22 John H. Livingston Ensembles d'injection pourvus d'elements de micro-perforation, utilises avec des dispositifs medicaux, et leurs procedes d'utilisation
CN2654137Y (zh) * 2003-11-04 2004-11-10 浙江大学 一种基于微加工技术的无痛微针阵列
US8206334B2 (en) * 2006-01-31 2012-06-26 Kralick Francis A Implantable micro-system for treatment of hydrocephalus
CN1830496A (zh) * 2006-04-10 2006-09-13 清华大学 “-”字形结构三维微型实心、空心硅针或刀
US20090326415A1 (en) 2006-08-28 2009-12-31 Agency For Science ,Technology And Research Microneedles and methods for fabricating microneedles
CN100998901B (zh) * 2007-01-12 2012-10-10 中国科学院上海微系统与信息技术研究所 多孔硅无痛注射微针阵列及其制备方法
US20090074831A1 (en) * 2007-09-18 2009-03-19 Robert Falotico LOCAL VASCULAR DELIVERY OF mTOR INHIBITORS IN COMBINATION WITH PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR STIMULATORS
JP2011500252A (ja) 2007-10-27 2011-01-06 デビオテック ソシエテ アノニム 極微針付き医療注射器具
US8808255B2 (en) * 2007-12-14 2014-08-19 Oregon Health & Science University Drug delivery cuff
EP3300765A1 (fr) * 2008-11-18 2018-04-04 3M Innovative Properties Co. Réseau de micro-aiguilles creuses
JPWO2010067882A1 (ja) 2008-12-12 2012-05-24 株式会社クレハ 癌及び喘息治療のための医薬組成物
JP2010168368A (ja) 2008-12-26 2010-08-05 Taisho Pharmaceutical Co Ltd Psma7、nedd1およびrae1遺伝子発現抑制剤の用途
CN101879336A (zh) * 2009-05-06 2010-11-10 中国科学院半导体研究所 用于皮下药物注射的基于柔性基底的微针阵列及其制法
EP2275164A1 (fr) 2009-07-15 2011-01-19 Debiotech S.A. Micro-aiguilles à multicanaux
JP2011078654A (ja) * 2009-10-09 2011-04-21 Asti Corp マイクロニードルアレイとマイクロニードルアレイの製造方法
KR101794376B1 (ko) * 2010-04-28 2017-11-06 킴벌리-클라크 월드와이드, 인크. siRNA 전달용 의료 기구
CN101912663B (zh) * 2010-08-18 2013-09-04 清华大学 空心微针阵列芯片、经皮给药贴片、器件及制备方法
CN102453713B (zh) * 2010-10-20 2014-02-19 中国医学科学院肿瘤研究所 HULC siRNA及其在制备治疗肝癌的药物中的用途
KR101241059B1 (ko) * 2011-03-04 2013-03-11 연세대학교 산학협력단 마이크로 니들을 이용한 혈관외벽 장착 약물 전달장치 및 약물 전달방법
EP2686058A1 (fr) * 2011-03-18 2014-01-22 Université Libre de Bruxelles Dispositifs pour la perforation d'une membrane du corps humain ou animal
KR101542549B1 (ko) * 2011-09-02 2015-08-06 산디아 코포레이션 바이오센싱 및 약물 전달을 위한 마이크로니들 어레이
CN103570594A (zh) * 2012-08-01 2014-02-12 苏州迈泰生物技术有限公司 二芳基胺类化合物及其在制备抗恶性肿瘤药物中的用途
CN104004822B (zh) * 2013-02-27 2018-08-07 霍克克 Ssx2ip在预测或诊断肿瘤转移中的应用
CN104043192B (zh) * 2014-06-28 2016-08-24 陈彦彪 一次性微针装置
CN105381536A (zh) * 2015-12-22 2016-03-09 无锡吉迈微电子有限公司 自行载药的长时透皮给药及取样装置

Also Published As

Publication number Publication date
EP3487575A1 (fr) 2019-05-29
JP7183145B2 (ja) 2022-12-05
JP2019524253A (ja) 2019-09-05
FR3054137A1 (fr) 2018-01-26
CN109475729A (zh) 2019-03-15
WO2018015690A1 (fr) 2018-01-25
US20210178136A1 (en) 2021-06-17
CA3031316A1 (fr) 2018-01-25

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