FR2879215B1 - Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica - Google Patents

Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica

Info

Publication number
FR2879215B1
FR2879215B1 FR0413468A FR0413468A FR2879215B1 FR 2879215 B1 FR2879215 B1 FR 2879215B1 FR 0413468 A FR0413468 A FR 0413468A FR 0413468 A FR0413468 A FR 0413468A FR 2879215 B1 FR2879215 B1 FR 2879215B1
Authority
FR
France
Prior art keywords
dicarboxylic acids
yarrowia lipolytica
production
mutant strains
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0413468A
Other languages
English (en)
French (fr)
Other versions
FR2879215A1 (fr
Inventor
Jean Marc Nicaud
France Theveniau
Dall Marie Therese Le
Remy Marchal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IFP Energies Nouvelles IFPEN
Original Assignee
IFP Energies Nouvelles IFPEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0413468A priority Critical patent/FR2879215B1/fr
Application filed by IFP Energies Nouvelles IFPEN filed Critical IFP Energies Nouvelles IFPEN
Priority to DE602005021913T priority patent/DE602005021913D1/de
Priority to ES05826569T priority patent/ES2346773T3/es
Priority to PL05826569T priority patent/PL1828392T3/pl
Priority to JP2007546115A priority patent/JP2008523794A/ja
Priority to DK05826569.5T priority patent/DK1828392T3/da
Priority to AT05826569T priority patent/ATE471384T1/de
Priority to EP05826569A priority patent/EP1828392B1/fr
Priority to PCT/FR2005/003140 priority patent/WO2006064131A1/fr
Priority to CN2005800483222A priority patent/CN101228282B/zh
Priority to US11/721,726 priority patent/US20100041115A1/en
Priority to BRPI0519928-0A priority patent/BRPI0519928A2/pt
Priority to CA2590795A priority patent/CA2590795C/fr
Publication of FR2879215A1 publication Critical patent/FR2879215A1/fr
Application granted granted Critical
Publication of FR2879215B1 publication Critical patent/FR2879215B1/fr
Priority to JP2012049322A priority patent/JP5462303B2/ja
Priority to JP2012049326A priority patent/JP5615859B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR0413468A 2004-12-15 2004-12-15 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica Expired - Fee Related FR2879215B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0413468A FR2879215B1 (fr) 2004-12-15 2004-12-15 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
US11/721,726 US20100041115A1 (en) 2004-12-15 2005-12-13 Production of dicarboxylic acids by improved mutant strains of yarrowia lipolytica
PL05826569T PL1828392T3 (pl) 2004-12-15 2005-12-13 Wytwarzanie kwasów dikarboksylowych przez ulepszone zmutowane szczepy Yarrowia lipolytica
JP2007546115A JP2008523794A (ja) 2004-12-15 2005-12-13 改善されたヤロウイア・リポリティカ変異株によるジカルボン酸の製造
DK05826569.5T DK1828392T3 (da) 2004-12-15 2005-12-13 Fremstilling af dicarboxylsyrer ved hjælp af forbedret mutantstamme af Yarrowia lipolytica
AT05826569T ATE471384T1 (de) 2004-12-15 2005-12-13 Herstellung von dicarbonsäure durch verbesserte yarrowia lipolytica-mutantenstämme
EP05826569A EP1828392B1 (fr) 2004-12-15 2005-12-13 Production d' acides dicarboxyliques par des souches mutantes ameliorées de yarrowia lipolytica
PCT/FR2005/003140 WO2006064131A1 (fr) 2004-12-15 2005-12-13 Production d’acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
DE602005021913T DE602005021913D1 (de) 2004-12-15 2005-12-13 Herstellung von dicarbonsäure durch verbesserte yarrowia lipolytica-mutantenstämme
ES05826569T ES2346773T3 (es) 2004-12-15 2005-12-13 Produccion de acidos dicarboxilicos mediante cepas mutantes mejoradas de yarrowia lipolytica.
BRPI0519928-0A BRPI0519928A2 (pt) 2004-12-15 2005-12-13 produção de ácidos dicarboxìlicos por cepas mutantes melhoradas de yarrowia lipolytica
CA2590795A CA2590795C (fr) 2004-12-15 2005-12-13 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
CN2005800483222A CN101228282B (zh) 2004-12-15 2005-12-13 利用解脂耶氏酵母改进突变株生产二羧酸
JP2012049322A JP5462303B2 (ja) 2004-12-15 2012-03-06 改善されたヤロウイア・リポリティカ変異株によるジカルボン酸の製造
JP2012049326A JP5615859B2 (ja) 2004-12-15 2012-03-06 改善されたヤロウイア・リポリティカ変異株によるジカルボン酸の製造

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0413468A FR2879215B1 (fr) 2004-12-15 2004-12-15 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica

Publications (2)

Publication Number Publication Date
FR2879215A1 FR2879215A1 (fr) 2006-06-16
FR2879215B1 true FR2879215B1 (fr) 2010-08-20

Family

ID=34954795

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0413468A Expired - Fee Related FR2879215B1 (fr) 2004-12-15 2004-12-15 Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica

Country Status (13)

Country Link
US (1) US20100041115A1 (enExample)
EP (1) EP1828392B1 (enExample)
JP (3) JP2008523794A (enExample)
CN (1) CN101228282B (enExample)
AT (1) ATE471384T1 (enExample)
BR (1) BRPI0519928A2 (enExample)
CA (1) CA2590795C (enExample)
DE (1) DE602005021913D1 (enExample)
DK (1) DK1828392T3 (enExample)
ES (1) ES2346773T3 (enExample)
FR (1) FR2879215B1 (enExample)
PL (1) PL1828392T3 (enExample)
WO (1) WO2006064131A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2927089B1 (fr) 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
DK2310517T3 (en) * 2008-07-11 2016-06-06 Inst Nat De La Rech Agronomique (Inra) Novel mutant yeast strains having a capability to accumulate a large amount of lipids
FR2957074B1 (fr) 2010-03-05 2012-04-27 Organisation Nationale Interprofessionnelle Des Graines Et Fruits Oleagineux O N I D O L Procede de preparation d'acides carboxyliques par coupure oxydante d'un diol vicinal
FR2962133B1 (fr) 2010-07-01 2014-09-12 Agronomique Inst Nat Rech Optimisation de la synthese et de l'accumulation de lipides
MY184871A (en) 2011-07-06 2021-04-28 Radici Chimica S P A Biological methods for preparing a fatty dicarboxylic acid
US9850493B2 (en) 2012-12-19 2017-12-26 Verdezyne, Inc. Biological methods for preparing a fatty dicarboxylic acid
JP2016501040A (ja) 2012-12-19 2016-01-18 ヴェルデザイン，インコーポレーテッド 脂肪族ジカルボン酸を調製するための生物学的方法
FR3002774A1 (fr) 2013-03-04 2014-09-05 Agronomique Inst Nat Rech Levures mutantes ayant une production accrue de lipides et d'acide citrique
FR3005317B1 (fr) 2013-05-02 2016-03-18 Agronomique Inst Nat Rech Levures mutantes capables de produire un acide gras inhabituel
DE102014220186B4 (de) 2013-12-12 2017-06-22 Technische Universität Dresden Hefestämme und Verfahren zur Produktion von Omega-Hydroxyfettsäuren und Dicarbonsäuren
EP3155094A1 (en) 2014-06-11 2017-04-19 Institut National De La Recherche Agronomique (INRA) Improved lipid accumulation in yarrowia lipolytica strains by overexpression of hexokinase and new strains thereof
US9695404B2 (en) 2014-07-18 2017-07-04 Industrial Technology Research Institute Genetically modified microorganism for producing long-chain dicarboxylic acid and method of using thereof
US10174350B2 (en) 2014-07-18 2019-01-08 Industrial Technology Research Institute Genetically modified microorganism for producing medium-chain lauric acid and/or dodecanedioic acid and method of using thereof
US9932665B2 (en) 2015-01-22 2018-04-03 United Technologies Corporation Corrosion resistant coating application method
CN107532186A (zh) * 2015-03-27 2018-01-02 油料作物与高蛋白作物领域发展基金会 微生物和其用于生产二酸的用途
EP3085788A1 (en) 2015-04-23 2016-10-26 Institut National De La Recherche Agronomique Mutant yeast strain capable of degrading cellobiose
EP3106520A1 (en) 2015-06-17 2016-12-21 Institut National De La Recherche Agronomique Mutant yarrowia strain capable of degrading galactose
JP6898915B2 (ja) 2015-07-22 2021-07-07 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 生物を用いる長鎖ジカルボン酸の高レベルの生産
US20180327724A1 (en) * 2015-10-27 2018-11-15 Korea Research Institute Of Bioscience And Biotechnology Method for producing heavy chain aminocarboxylic acid
US20190136278A1 (en) 2016-05-10 2019-05-09 Institut National De La Recherche Agronomique Mutant yeast strains with enhanced production of erythritol or erythrulose
EP3348647A1 (en) 2017-01-13 2018-07-18 Institut National De La Recherche Agronomique Mutant yeast strain capable of producing medium chain fatty acids
EP3360956A1 (en) 2017-02-10 2018-08-15 Institut National De La Recherche Agronomique Mutant yeast strain capable of degrading cellulose
CN107083338A (zh) * 2017-05-15 2017-08-22 天津大学 重组菌株及其构建方法与在产菜油甾醇中的应用
EP3652300A4 (en) 2017-07-13 2021-06-23 Radici Chimica S.p.A. BIOLOGICAL PROCEDURES FOR MODIFYING CELLULAR CARBON FLOW
US11136596B2 (en) * 2018-07-06 2021-10-05 Cibt America Inc. Long-chain dibasic acid with low content of hydroxyl acid impurity and production method thereof
CN110684676B (zh) * 2018-07-06 2023-08-08 上海凯赛生物技术股份有限公司 一种低含量羟基酸杂质的长链二元酸及其生产方法
CN111117982B (zh) * 2019-12-25 2023-05-12 武汉新华扬生物股份有限公司 一种拟除虫菊酯降解酶、其编码基因、重组菌株和应用
US20230089404A1 (en) 2021-09-18 2023-03-23 Indian Oil Corporation Limited Bioassisted Process For Selective Conversion Of Alkane Rich Refinery Stream
CN114958900B (zh) * 2022-05-16 2024-04-19 华中科技大学 一种解脂耶氏酵母高效无标记基因整合载体及其应用

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DE3540834A1 (de) 1985-11-18 1987-05-21 Henkel Kgaa Verfahren zur herstellung von dicarbonsaeuren
US5254466A (en) 1989-11-06 1993-10-19 Henkel Research Corporation Site-specific modification of the candida tropicals genome
WO1991014781A1 (en) * 1990-03-19 1991-10-03 Henkel Research Corporation METHOD FOR INCREASING THE OMEGA-HYDROXYLASE ACTIVITY IN $i(CANDIDA TROPICALIS)
US6673613B2 (en) * 2000-07-26 2004-01-06 Cognis Corporation Use of CYP52A2A promoter to increase gene expression in yeast
EP1506302A4 (en) * 2002-05-23 2006-02-08 Cognis Ip Man Gmbh CANDIDA TROPICALIS BLOCKED BY OXIDATION BETA NON REVERSIBLE

Also Published As

Publication number Publication date
JP5462303B2 (ja) 2014-04-02
EP1828392A1 (fr) 2007-09-05
EP1828392B1 (fr) 2010-06-16
CN101228282B (zh) 2013-09-18
WO2006064131A1 (fr) 2006-06-22
CA2590795A1 (fr) 2006-06-22
BRPI0519928A2 (pt) 2009-04-07
CN101228282A (zh) 2008-07-23
CA2590795C (fr) 2014-09-02
DE602005021913D1 (de) 2010-07-29
JP2008523794A (ja) 2008-07-10
PL1828392T3 (pl) 2011-04-29
ES2346773T3 (es) 2010-10-20
ATE471384T1 (de) 2010-07-15
FR2879215A1 (fr) 2006-06-16
JP2012105680A (ja) 2012-06-07
JP2012130352A (ja) 2012-07-12
JP5615859B2 (ja) 2014-10-29
WO2006064131A8 (fr) 2007-08-02
DK1828392T3 (da) 2010-09-27
US20100041115A1 (en) 2010-02-18

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