FR2873704B1 - Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques - Google Patents

Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques

Info

Publication number
FR2873704B1
FR2873704B1 FR0408478A FR0408478A FR2873704B1 FR 2873704 B1 FR2873704 B1 FR 2873704B1 FR 0408478 A FR0408478 A FR 0408478A FR 0408478 A FR0408478 A FR 0408478A FR 2873704 B1 FR2873704 B1 FR 2873704B1
Authority
FR
France
Prior art keywords
vectorization
anionic charge
polyamino acids
hydrophobic
active principles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0408478A
Other languages
English (en)
French (fr)
Other versions
FR2873704A1 (fr
Inventor
Olivier Breyne
Gauthier Pouliquen
You Ping Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0408478A priority Critical patent/FR2873704B1/fr
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Priority to US11/658,803 priority patent/US20100098656A1/en
Priority to CA002573612A priority patent/CA2573612A1/fr
Priority to EP05792029A priority patent/EP1773914B9/fr
Priority to JP2007523129A priority patent/JP5324093B2/ja
Priority to AT05792029T priority patent/ATE449806T1/de
Priority to PCT/FR2005/050610 priority patent/WO2006021710A1/fr
Priority to DE602005017903T priority patent/DE602005017903D1/de
Publication of FR2873704A1 publication Critical patent/FR2873704A1/fr
Application granted granted Critical
Publication of FR2873704B1 publication Critical patent/FR2873704B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88—Polyamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48—Polymers modified by chemical after-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Polyamides (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0408478A 2004-07-30 2004-07-30 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques Expired - Fee Related FR2873704B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0408478A FR2873704B1 (fr) 2004-07-30 2004-07-30 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques
CA002573612A CA2573612A1 (fr) 2004-07-30 2005-07-25 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques
EP05792029A EP1773914B9 (fr) 2004-07-30 2005-07-25 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques
JP2007523129A JP5324093B2 (ja) 2004-07-30 2005-07-25 負電荷を有する疎水性基で官能基化された分岐鎖ポリアミノ酸、及びその応用、特に治療への応用
US11/658,803 US20100098656A1 (en) 2004-07-30 2005-07-25 Polyamino acids functionalized by hydrophobic grafts bearing an anionic charge and applications thereof, such as therapeutic applications
AT05792029T ATE449806T1 (de) 2004-07-30 2005-07-25 Mittels wasserabweisender implantate mit anionischer ladung funktionalisierte polyaminosäuren und anwendungen, wie etwa therapeutische anwendungen dafür
PCT/FR2005/050610 WO2006021710A1 (fr) 2004-07-30 2005-07-25 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques
DE602005017903T DE602005017903D1 (de) 2004-07-30 2005-07-25 Mittels wasserabweisender implantate mit anionischer ladung funktionalisierte polyaminosäuren und anwendungen, wie etwa therapeutische anwendungen dafür

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0408478A FR2873704B1 (fr) 2004-07-30 2004-07-30 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques

Publications (2)

Publication Number Publication Date
FR2873704A1 FR2873704A1 (fr) 2006-02-03
FR2873704B1 true FR2873704B1 (fr) 2006-12-08

Family

ID=34949825

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0408478A Expired - Fee Related FR2873704B1 (fr) 2004-07-30 2004-07-30 Polyaminoacides fonctionnalises par des greffons hydrophobes portant une charge anionique et leurs applications notamment therapeutiques

Country Status (8)

Country Link
US (1) US20100098656A1 (https=)
EP (1) EP1773914B9 (https=)
JP (1) JP5324093B2 (https=)
AT (1) ATE449806T1 (https=)
CA (1) CA2573612A1 (https=)
DE (1) DE602005017903D1 (https=)
FR (1) FR2873704B1 (https=)
WO (1) WO2006021710A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4992090B2 (ja) * 2005-05-02 2012-08-08 国立大学法人 東京大学 静電結合型高分子ベシクル
FR2915684B1 (fr) * 2007-05-03 2011-01-14 Flamel Tech Sa Particules a base de polyelectrolytes et de principe actif a liberation modifiee et formulations pharmaceutiques contenant ces particules
US7999040B2 (en) 2007-09-25 2011-08-16 Nanochem Solutions, Inc. Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer
WO2009041913A1 (en) * 2007-09-26 2009-04-02 Thorsson Limited Colloidal fertilizer and related methods
US20110060123A1 (en) 2008-04-30 2011-03-10 Kazunori Kataoka Charge conversional ternary polyplex
EP3653584B1 (en) 2010-02-10 2025-08-06 Queen's University At Kingston Draw solution with switchable salt additive and method for desalinating an aqueous solution with this draw solution
JP2013234207A (ja) * 2010-08-31 2013-11-21 Jsr Corp 新規重合体及び新規ｎ−カルボキシアミノ酸無水物、ならびにそれらの製造方法
CN103459439B (zh) 2010-12-15 2017-09-12 金斯顿女王大学 使用具有可转换的离子强度的水的系统和方法
CN111698999A (zh) * 2017-12-06 2020-09-22 阿道恰公司 包含至少一种pi在5.8与8.5之间的基础胰岛素和带有羧酸根电荷及疏水基的共聚氨基酸的ph为7的可注射溶液
BR112020011479A2 (pt) * 2017-12-07 2020-11-17 Adocia composições na forma de uma solução aquosa injetável caracterizada pelo fato de que compreende amilina, um agonista do receptor de amilina ou um análogo de amilina e um co-poliaminoácido
TW201938190A (zh) * 2017-12-07 2019-10-01 法商阿道洽公司 包含至少一具有pi從5.8至8.5之基礎胰島素以及一帶有羧酸鹽電荷及疏水基之共聚胺基酸的ph 7之可注射溶液
WO2019110797A1 (fr) * 2017-12-07 2019-06-13 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
TWI813604B (zh) 2017-12-07 2023-09-01 法商阿道洽公司 包含至少一具有pi從5.8至8.5之基礎胰島素以及一帶有羧酸鹽電荷及疏水基之共聚胺基酸的可注射ph7溶液
MX2020005916A (es) 2017-12-07 2020-10-19 Adocia Composiciones en forma de una solución acuosa inyectable que comprende amilina, un receptor agonista de amilina o un análogo de amilina y un copoliaminoácido.
CN109498548B (zh) * 2018-12-11 2021-09-24 吉林化工学院 一种蛋白质与光敏剂共传递pH响应性聚氨基酸纳米凝胶及其制备方法
JP2024515444A (ja) * 2021-03-18 2024-04-10 アグフア－ゲヴエルト，ナームローゼ・フエンノートシヤツプ ポリ（アミノ酸）系カプセル

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
ATE60340T1 (de) * 1984-10-19 1991-02-15 Battelle Memorial Institute Durch mikroorganismen abbaubares polypeptid und seine verwendung fuer die fortschreitende abgabe von medikamenten.
CH667874A5 (fr) * 1985-12-19 1988-11-15 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
KR940003548U (ko) * 1992-08-14 1994-02-21 김형술 세탁물 건조기
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
FR2732218B1 (fr) * 1995-03-28 1997-08-01 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation
FR2786098B1 (fr) * 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
CN1538985A (zh) * 2001-08-03 2004-10-20 用于洗涤剂组合物中的聚天冬氨酸衍生物
JP2003327693A (ja) * 2002-05-15 2003-11-19 Mitsuru Akashi 親−疎水性修飾ポリ（γ−グルタミン酸）
FR2840614B1 (fr) * 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2843117B1 (fr) * 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
WO2004060968A1 (fr) * 2002-12-04 2004-07-22 Flamel Technologies Polyaminoacides fonctionnalises par au moins un groupement (oligo)aminoacide et leurs applications notamment therapeutiques
FR2855521B1 (fr) * 2003-05-28 2005-08-05 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
FR2873703B1 (fr) * 2004-07-30 2006-12-08 Flamel Technologies Sa Polyaminoacides branches, fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques

Also Published As

Publication number Publication date
EP1773914B9 (fr) 2010-03-31
EP1773914A1 (fr) 2007-04-18
JP2008508389A (ja) 2008-03-21
US20100098656A1 (en) 2010-04-22
JP5324093B2 (ja) 2013-10-23
DE602005017903D1 (de) 2010-01-07
ATE449806T1 (de) 2009-12-15
CA2573612A1 (fr) 2006-03-02
EP1773914B1 (fr) 2009-11-25
WO2006021710A1 (fr) 2006-03-02
FR2873704A1 (fr) 2006-02-03

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Legal Events

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Effective date: 20120330