FR2859996B1 - Solvat acetonique du dimethoxy docetaxel et son procede de preparation - Google Patents
Solvat acetonique du dimethoxy docetaxel et son procede de preparationInfo
- Publication number
- FR2859996B1 FR2859996B1 FR0311016A FR0311016A FR2859996B1 FR 2859996 B1 FR2859996 B1 FR 2859996B1 FR 0311016 A FR0311016 A FR 0311016A FR 0311016 A FR0311016 A FR 0311016A FR 2859996 B1 FR2859996 B1 FR 2859996B1
- Authority
- FR
- France
- Prior art keywords
- solvat
- acetonic
- preparing
- same
- dimethoxy docetaxel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (43)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0311016A FR2859996B1 (fr) | 2003-09-19 | 2003-09-19 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| PE2004000799A PE20050870A1 (es) | 2003-09-19 | 2004-08-19 | Solvato acetonico del dimetoxi docetaxel y su procedimiento de preparacion |
| KR1020067005396A KR101123588B1 (ko) | 2003-09-19 | 2004-09-16 | 디메톡시 도세탁셀 아세톤 용매화물 및 이의 제조 방법 |
| ES04787385T ES2403149T4 (es) | 2003-09-19 | 2004-09-16 | Solvato acetónico de dimetoxi docetaxel y su procedimiento de preparación |
| PA20048612401A PA8612401A1 (es) | 2003-09-19 | 2004-09-16 | Solvato acetonico del dimetoxi docetaxel y su procedimiento de preparacion |
| PT4787385T PT1667986E (pt) | 2003-09-19 | 2004-09-16 | Solvato de acetona de dimetoxi docetaxel e processo para a sua preparação |
| BRPI0414492A BRPI0414492A8 (pt) | 2003-09-19 | 2004-09-16 | solvato acetônico do dimetóxi docetaxel e seu processo de preparação |
| CNB200480026128XA CN100429207C (zh) | 2003-09-19 | 2004-09-16 | 二甲氧基多西他赛丙酮化物及其制备方法 |
| EP04787385A EP1667986B1 (fr) | 2003-09-19 | 2004-09-16 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| CA002539309A CA2539309A1 (fr) | 2003-09-19 | 2004-09-16 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| MEP-2008-117A ME00054B (me) | 2003-09-19 | 2004-09-16 | Acetonski solvati dimetoksi docetaksela i postupci za njihovo dobijanje |
| YUP-2006/0189A RS20060189A (en) | 2003-09-19 | 2004-09-16 | Dimethoxy docetaxel acetone solvate et method for the preparation thereof |
| MXPA06002639A MXPA06002639A (es) | 2003-09-19 | 2004-09-16 | Solvato acetonico del dimetoxi docetaxel y su procedimiento de preparacion. |
| RS20060189A RS54614B1 (en) | 2003-09-19 | 2004-09-16 | Acetone solvate dimethoxy docetaxel and procedure for its production |
| DK04787385.6T DK1667986T3 (da) | 2003-09-19 | 2004-09-16 | Acetonesolvat af dimethoxydocetaxel og fremgangsmåde til fremstilling heraf |
| MEP-117/08A MEP11708A (en) | 2003-09-19 | 2004-09-16 | Dimethoxy docetaxel acetone solvate et method for the preparation thereof |
| PCT/FR2004/002344 WO2005028462A1 (fr) | 2003-09-19 | 2004-09-16 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| PL04787385T PL1667986T3 (pl) | 2003-09-19 | 2004-09-16 | Solwat acetonowy dimetoksydocetakselu i sposób jego wytwarzania |
| RU2006113122/04A RU2342373C2 (ru) | 2003-09-19 | 2004-09-16 | Ацетоновый сольват диметоксидоцетаксела и способ его получения |
| SI200432016T SI1667986T1 (sl) | 2003-09-19 | 2004-09-16 | Acetonski solvat dimetoksi docetaksela in postopek za njegovo pripravo |
| JP2006526663A JP5010279B2 (ja) | 2003-09-19 | 2004-09-16 | ジメトキシドセタキセル・アセトン溶媒和物およびその製造方法 |
| NZ545835A NZ545835A (en) | 2003-09-19 | 2004-09-16 | Dimethoxy docetaxel acetone solvate and method for the preparation thereof |
| UAA200604360A UA87115C2 (ru) | 2003-09-19 | 2004-09-16 | Ацетоновый сольват диметоксидоцетаксела и способ его получения |
| ARP040103329A AR045667A1 (es) | 2003-09-19 | 2004-09-16 | Solvato acetonico del dimetoxi docetaxel y su procedimiento de preparacion |
| AU2004274212A AU2004274212B2 (en) | 2003-09-19 | 2004-09-16 | Dimethoxy docetaxel acetone solvate et method for the preparation thereof |
| MYPI20043787A MY136668A (en) | 2003-09-19 | 2004-09-17 | Acetone solvate of dimethoxydocetaxel and its process of preparation |
| TW093128097A TWI382022B (zh) | 2003-09-19 | 2004-09-17 | 二甲氧基剋癌易（ｄｏｃｅｔａｘｅｌ）之丙酮溶劑合物及其製法 |
| US10/944,254 US7241907B2 (en) | 2003-09-19 | 2004-09-17 | Acetone solvate of dimethoxy docetaxel and its process of preparation |
| IL174240A IL174240A (en) | 2003-09-19 | 2006-03-09 | Dimethoxy docetaxel acetone solvate and method for the preparation thereof |
| CR8292A CR8292A (es) | 2003-09-19 | 2006-03-15 | Solvato acetonico del dimetoxi docetaxel y su procedimiento de preparacion |
| ZA200602255A ZA200602255B (en) | 2003-09-19 | 2006-03-17 | Dimethoxy docetaxel acetone solvate and method for the preparation thereof |
| TNP2006000086A TNSN06086A1 (en) | 2003-09-19 | 2006-03-17 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| MA28881A MA28045A1 (fr) | 2003-09-19 | 2006-03-17 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| NO20061714A NO335997B1 (no) | 2003-09-19 | 2006-04-19 | Dimetoksydocetaksel-acetonsolvat og fremgangsmåte for fremstilling derav |
| HK06114182.3A HK1093340A1 (en) | 2003-09-19 | 2006-12-28 | Dimethoxy docetaxel acetone solvate et method for the preparation thereof |
| LU92172C LU92172I2 (fr) | 2003-09-19 | 2013-03-20 | Solvat acétonique du cabazitaxel, ou désigné solvat acétonique du diméthoxy docetaxel ou solvat acétonique du (2R,3S)-3-tertbutoxycarbonylamino-2-hydroxy-3-phénylpropionate de 4-acetoxy-2a-benzoyloxy-5ß,20-époxy-1-hydroxy-7ß,10a-diméthoxy-9-oxo-tax-11-ène-13a-yle (acétonate du cabazitaxel) |
| HRP20130322TT HRP20130322T1 (en) | 2003-09-19 | 2013-04-10 | Dimethoxy docetaxel acetone solvate et method for the preparation thereof |
| CY20131100313T CY1114575T1 (el) | 2003-09-19 | 2013-04-16 | Διαλυμα ακετονης διμεθοξυ δοσεταξελης και η διαδικασια παρασκευης του |
| CY2013016C CY2013016I2 (el) | 2003-09-19 | 2013-05-13 | Διαλυμα ακετονης διμεθοξυ δοσεταξελης και η διαδικασια παρασκευης του |
| HUS1300025C HUS1300025I1 (hu) | 2003-09-19 | 2013-06-07 | Dimetoxidocetaxel aceton-szolvátja és eljárás ennek elõállítására |
| BE2013C036C BE2013C036I2 (US07576130-20090818-C00114.png) | 2003-09-19 | 2013-06-13 | |
| FR13C0037C FR13C0037I2 (fr) | 2003-09-19 | 2013-07-04 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| NO2015013C NO2015013I1 (no) | 2003-09-19 | 2015-04-22 | Cabazitaxel acetonat, også betegnet acetonsolvat av cabazitaxel eller acetonsolvat av imetoksydocetaxel, eller acetonsolvat av 4-acetoksy-2¿-benzoyloksy-5ß,20-epoksy-1-hydroksy-ß,10ßdimetoksy-9-oksotaks-11-en-13¿-yl (2R,3S)-3-tertbutoksykarbonylamino-2-hydroksy-3-fenylpropionat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0311016A FR2859996B1 (fr) | 2003-09-19 | 2003-09-19 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2859996A1 FR2859996A1 (fr) | 2005-03-25 |
| FR2859996B1 true FR2859996B1 (fr) | 2006-02-03 |
Family
ID=34224354
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR0311016A Expired - Lifetime FR2859996B1 (fr) | 2003-09-19 | 2003-09-19 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| FR13C0037C Active FR13C0037I2 (fr) | 2003-09-19 | 2013-07-04 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR13C0037C Active FR13C0037I2 (fr) | 2003-09-19 | 2013-07-04 | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
Country Status (38)
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007109654A2 (en) * | 2006-03-21 | 2007-09-27 | Dr. Reddy's Laboratories Ltd. | Docetaxel polymorphs and processes |
| US7855591B2 (en) * | 2006-06-07 | 2010-12-21 | Atmel Corporation | Method and system for providing a charge pump very low voltage applications |
| US7652522B2 (en) * | 2006-09-05 | 2010-01-26 | Atmel Corporation | High efficiency low cost bi-directional charge pump circuit for very low voltage applications |
| JP2010516625A (ja) | 2007-01-24 | 2010-05-20 | インサート セラピューティクス， インコーポレイテッド | 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート |
| FR2926551A1 (fr) * | 2008-01-17 | 2009-07-24 | Aventis Pharma Sa | Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation |
| AU2013205442B2 (en) * | 2008-01-17 | 2016-05-12 | Aventis Pharma S.A. | Crystalline forms of dimethoxy docetaxel and methods for preparing same |
| EP2331140B1 (en) | 2008-08-11 | 2018-07-04 | Nektar Therapeutics | Multi-arm polymeric alkanoate conjugates |
| FR2945211A1 (fr) * | 2009-05-06 | 2010-11-12 | Sanofi Aventis | Combinaison antitumorale comprenant la cabazitaxel et la capecitabine |
| WO2011051894A1 (en) | 2009-10-29 | 2011-05-05 | Aventis Pharma S.A. | Novel antitumoral use of cabazitaxel |
| CA2708489A1 (en) * | 2009-10-29 | 2011-04-29 | Aventis Pharma S.A. | Use of cabazitaxel and a prednisone or a prednisolone in the treatment of prostate cancer |
| AU2015200149B2 (en) * | 2009-10-29 | 2016-12-01 | Aventis Pharma S.A. | Novel antitumoral use of cabazitaxel |
| US10894087B2 (en) | 2010-12-22 | 2021-01-19 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds |
| US20130331443A1 (en) | 2010-12-22 | 2013-12-12 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of taxane-based compounds |
| CN103764637A (zh) * | 2011-04-12 | 2014-04-30 | 普拉斯化学品有限公司 | 卡巴他赛的固态形式及其制备方法 |
| WO2013024495A1 (en) * | 2011-08-18 | 2013-02-21 | Dr. Reddys Laboratories Limited | Pharmaceutical formulations of cabazitaxel |
| TWI526437B (zh) | 2011-09-09 | 2016-03-21 | 台灣神隆股份有限公司 | 卡巴他賽之結晶型 |
| CN103906747A (zh) | 2011-10-31 | 2014-07-02 | 台湾神隆股份有限公司 | 卡巴他赛及其中间体的制备方法 |
| EP2773629B1 (en) | 2011-11-01 | 2018-04-11 | Fresenius Kabi Oncology Limited | Process for the preparation of an amorphous form of cabazitaxel |
| DE112012004944T5 (de) | 2011-11-28 | 2014-12-11 | Fresenius Kabi Oncology Ltd. | Kristalline Formen von Cabazitaxel und deren Herstellungsverfahren |
| WO2013088335A1 (en) | 2011-12-13 | 2013-06-20 | Aventis Pharma S.A. | Crystalline form of cabazitaxel and process for preparing the same |
| US9403785B2 (en) | 2012-01-03 | 2016-08-02 | Shilpa Medicare Limited | Process for preparing amorphous cabazitaxel |
| BR112014019675A2 (pt) * | 2012-02-10 | 2017-07-11 | Aventis Pharma Sa | usos pediátricos de cabazitaxel |
| US9394266B2 (en) | 2012-03-08 | 2016-07-19 | IVAX International GmbH | Solid state forms of cabazitaxel and processes for preparation thereof |
| CN102675257B (zh) * | 2012-05-10 | 2014-07-02 | 上海金和生物技术有限公司 | 一种卡巴他赛晶体及其制备方法 |
| CN102746258B (zh) | 2012-07-25 | 2015-02-04 | 重庆泰濠制药有限公司 | 卡巴他赛的结晶形式及其制备方法 |
| EP2880021A4 (en) | 2012-07-31 | 2015-06-17 | Yung Shin Pharm Ind Co Ltd | AMORPHIC CABACITAXEL |
| WO2014028704A1 (en) | 2012-08-15 | 2014-02-20 | Yung Shin Pharm. Ind. Co., Ltd. | Stable pharmaceutical formulation of cabazitaxel |
| CN103664836B (zh) * | 2012-09-20 | 2016-04-20 | 齐鲁制药有限公司 | 7β,10β-二甲氧基多西紫杉醇氘代丙酮合物的晶型A及其制备方法 |
| US20140094432A1 (en) | 2012-10-02 | 2014-04-03 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
| CN103804323A (zh) * | 2012-11-14 | 2014-05-21 | 上海希迈医药科技有限公司 | 一种卡巴他赛溶剂化物及其制备方法和应用 |
| CN103058960B (zh) * | 2012-12-12 | 2014-12-10 | 江苏奥赛康药业股份有限公司 | 卡巴他赛多晶型形式及其制备方法 |
| EP2743264A1 (en) | 2012-12-13 | 2014-06-18 | INDENA S.p.A. | New crystalline form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof |
| CN103910698B (zh) * | 2012-12-30 | 2016-01-20 | 上海医药工业研究院 | 卡巴他赛丙酮合物及其结晶 |
| CN103910696B (zh) * | 2012-12-30 | 2016-01-20 | 上海医药工业研究院 | 卡巴他赛异丙醚合物及其结晶 |
| EP2777691A1 (en) | 2013-03-14 | 2014-09-17 | Pharmachemie B.V. | Taxoid - Purification of Liquid Excipients |
| EP2815749A1 (en) | 2013-06-20 | 2014-12-24 | IP Gesellschaft für Management mbH | Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern |
| WO2015000165A1 (zh) * | 2013-07-04 | 2015-01-08 | 北京新天宇科技开发有限公司 | 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法 |
| CN104277014A (zh) * | 2013-07-04 | 2015-01-14 | 北京新天宇科技开发有限公司 | 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法 |
| EP2865674A1 (en) | 2013-10-23 | 2015-04-29 | INDENA S.p.A. | Crystalline solvate forms of Cabazitaxel |
| EP2865675A1 (en) * | 2013-10-23 | 2015-04-29 | INDENA S.p.A. | A crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof |
| CN103601704B (zh) * | 2013-11-22 | 2015-05-06 | 石家庄智恒医药科技有限公司 | 无定形卡巴他赛的制备 |
| WO2016113752A2 (en) | 2015-01-12 | 2016-07-21 | Emcure Pharmaceuticals Limited | Liquid formulation of cabazitaxel |
| PL3258931T3 (pl) * | 2015-02-17 | 2020-12-28 | Erasmus University Medical Center Rotterdam | Zastosowanie kabazitakselu w leczeniu nowotworu złośliwego prostaty |
| EP3093014A1 (en) | 2015-05-13 | 2016-11-16 | Aventis Pharma S.A. | Cabazitaxel and its use for treating cancer |
| US10188626B2 (en) | 2015-11-03 | 2019-01-29 | Cipla Limited | Stabilized cabazitaxel formulations |
| MX2019006207A (es) | 2016-11-29 | 2019-11-18 | Censa Pharmaceuticals Inc | Forma polimorfica de sepiapterina. |
| IL266955B2 (en) | 2016-11-29 | 2023-09-01 | Ptc Therapeutics Mp Inc | Polymorphs of spiafatrin and its salts |
| JP2020532535A (ja) | 2017-09-01 | 2020-11-12 | ピーティーシー セラピューティクス エムピー，インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
| FI3801536T3 (fi) | 2018-05-30 | 2024-08-29 | Ptc Therapeutics Mp Inc | Sepiapteriinin antaminen ilman ruokaa käytettäväksi menetelmässä sepiapteriinin plasma-altistuksen lisäämiseksi |
| WO2020249507A1 (en) | 2019-06-11 | 2020-12-17 | Indena S.P.A. | Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it |
| EP3808345A1 (en) | 2019-10-15 | 2021-04-21 | Sanofi Mature IP | Cabazitaxel in mcrpc patients previously treated with docetaxel and who failed a prior androgen signaling targeted inhibitor agent |
| EP3797834A1 (en) | 2019-09-25 | 2021-03-31 | Sanofi Mature IP | Cabazitaxel in mcrpc patients previously treated with docetaxel and who failed a prior androgen signaling targeted inhibitor agent |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5766635A (en) * | 1991-06-28 | 1998-06-16 | Rhone-Poulenc Rorer S.A. | Process for preparing nanoparticles |
| MA23823A1 (fr) * | 1995-03-27 | 1996-10-01 | Aventis Pharma Sa | Nouveaux taxoides, leur preparation et les compositions qui les contiennent |
| FR2745814B1 (fr) * | 1996-03-06 | 1998-04-03 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2771092B1 (fr) | 1997-11-18 | 1999-12-17 | Rhone Poulenc Rorer Sa | Procede de preparation de derives de la classe des taxoides |
| EP0982027A1 (en) * | 1998-08-17 | 2000-03-01 | Aventis Pharma S.A. | Taxoid derivatives for treating abnormal cell proliferation of the brain |
| US6346543B1 (en) * | 1998-08-17 | 2002-02-12 | Aventis Pharma S.A. | Use of a taxoid to treat abnormal cell proliferation in the brain |
| US6136989A (en) * | 1998-12-30 | 2000-10-24 | Phytogen Life Sciences, Incorporated | Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material |
| US5969165A (en) * | 1999-01-07 | 1999-10-19 | 508037 (Nb) Inc. | Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column |
| ES2211550T3 (es) * | 1999-05-17 | 2004-07-16 | Bristol-Myers Squibb Company | Nuevas condiciones de reaccion para la escision de eteres de sililo en la preparacion de paclitaxel (taxol(r)) y analogos de paclitaxel. |
| RU2284328C2 (ru) * | 2001-11-29 | 2006-09-27 | Дайити Фармасьютикал Ко., Лтд. | Кристаллы производных таксана и способ их получения |
-
2003
- 2003-09-19 FR FR0311016A patent/FR2859996B1/fr not_active Expired - Lifetime
-
2004
- 2004-08-19 PE PE2004000799A patent/PE20050870A1/es not_active Application Discontinuation
- 2004-09-16 RS YUP-2006/0189A patent/RS20060189A/sr unknown
- 2004-09-16 BR BRPI0414492A patent/BRPI0414492A8/pt not_active Application Discontinuation
- 2004-09-16 PT PT4787385T patent/PT1667986E/pt unknown
- 2004-09-16 PA PA20048612401A patent/PA8612401A1/es unknown
- 2004-09-16 EP EP04787385A patent/EP1667986B1/fr not_active Expired - Lifetime
- 2004-09-16 ME MEP-117/08A patent/MEP11708A/xx unknown
- 2004-09-16 DK DK04787385.6T patent/DK1667986T3/da active
- 2004-09-16 RU RU2006113122/04A patent/RU2342373C2/ru active Protection Beyond IP Right Term
- 2004-09-16 AU AU2004274212A patent/AU2004274212B2/en active Active
- 2004-09-16 KR KR1020067005396A patent/KR101123588B1/ko active IP Right Grant
- 2004-09-16 WO PCT/FR2004/002344 patent/WO2005028462A1/fr active Application Filing
- 2004-09-16 NZ NZ545835A patent/NZ545835A/en not_active IP Right Cessation
- 2004-09-16 CN CNB200480026128XA patent/CN100429207C/zh not_active Expired - Lifetime
- 2004-09-16 SI SI200432016T patent/SI1667986T1/sl unknown
- 2004-09-16 JP JP2006526663A patent/JP5010279B2/ja not_active Expired - Lifetime
- 2004-09-16 PL PL04787385T patent/PL1667986T3/pl unknown
- 2004-09-16 CA CA002539309A patent/CA2539309A1/fr not_active Abandoned
- 2004-09-16 ME MEP-2008-117A patent/ME00054B/me unknown
- 2004-09-16 UA UAA200604360A patent/UA87115C2/ru unknown
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