FR2837824B1 - Nouveaux derives de la podophyllotoxine, leur preparation et leur application en therapeutique - Google Patents

Nouveaux derives de la podophyllotoxine, leur preparation et leur application en therapeutique

Info

Publication number
FR2837824B1
FR2837824B1 FR0203903A FR0203903A FR2837824B1 FR 2837824 B1 FR2837824 B1 FR 2837824B1 FR 0203903 A FR0203903 A FR 0203903A FR 0203903 A FR0203903 A FR 0203903A FR 2837824 B1 FR2837824 B1 FR 2837824B1
Authority
FR
France
Prior art keywords
preparation
therapeutic application
podophyllotoxin derivatives
novel podophyllotoxin
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0203903A
Other languages
English (en)
Other versions
FR2837824A1 (fr
Inventor
Pierre Potier
Brahim Kerkar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR0203903A priority Critical patent/FR2837824B1/fr
Priority to AU2003244727A priority patent/AU2003244727A1/en
Priority to PCT/FR2003/000983 priority patent/WO2003082875A2/fr
Publication of FR2837824A1 publication Critical patent/FR2837824A1/fr
Application granted granted Critical
Publication of FR2837824B1 publication Critical patent/FR2837824B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
FR0203903A 2002-03-28 2002-03-28 Nouveaux derives de la podophyllotoxine, leur preparation et leur application en therapeutique Expired - Fee Related FR2837824B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0203903A FR2837824B1 (fr) 2002-03-28 2002-03-28 Nouveaux derives de la podophyllotoxine, leur preparation et leur application en therapeutique
AU2003244727A AU2003244727A1 (en) 2002-03-28 2003-03-28 Novel podophyllotoxin derivatives, the production thereof and the use of the same in therapeutics
PCT/FR2003/000983 WO2003082875A2 (fr) 2002-03-28 2003-03-28 Nouveaux derives de la podophyllotoxine, leur preparation e tleur application en therapeutique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0203903A FR2837824B1 (fr) 2002-03-28 2002-03-28 Nouveaux derives de la podophyllotoxine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2837824A1 FR2837824A1 (fr) 2003-10-03
FR2837824B1 true FR2837824B1 (fr) 2006-03-03

Family

ID=27839278

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0203903A Expired - Fee Related FR2837824B1 (fr) 2002-03-28 2002-03-28 Nouveaux derives de la podophyllotoxine, leur preparation et leur application en therapeutique

Country Status (3)

Country Link
AU (1) AU2003244727A1 (fr)
FR (1) FR2837824B1 (fr)
WO (1) WO2003082875A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7342114B2 (en) * 2003-07-01 2008-03-11 California Pacific Medical Center Podophyllotoxin derivatives
CN100334090C (zh) * 2005-02-02 2007-08-29 南京医科大学 吡啶类鬼臼毒素化合物及其制备方法和在制备杀虫剂中的应用
CN102875565B (zh) * 2012-09-29 2015-03-25 湖北工业大学 具有抗肿瘤活性的酯化鬼臼类衍生物及其制备方法和用途
CN104672249A (zh) * 2013-11-26 2015-06-03 上海医药工业研究院 鬼臼毒素衍生物、其制备方法、药物组合物及应用
KR101579054B1 (ko) * 2014-03-26 2015-12-21 한국원자력의학원 포도필로톡신 아세테이트를 유효 성분으로 포함하는 방사선치료 증진제
CN104557962A (zh) * 2014-12-17 2015-04-29 江苏科技大学 鬼臼毒素杂环脂类衍生物及其合成方法和应用
CN105250265B (zh) * 2015-08-27 2017-10-03 遵义医学院 鬼臼毒素靛红类衍生物在抗白血病药物中的应用及制备方法
CN106937529B (zh) 2015-10-27 2021-02-05 加州太平洋医疗中心 鬼臼毒素衍生物及其应用
US10087194B2 (en) 2015-10-27 2018-10-02 California Pacific Medical Center Podophyllotoxin derivatives and their use
CN110563739A (zh) * 2018-06-05 2019-12-13 薪火炙药(北京)科技有限公司 具有选择性抗肺癌作用的鬼臼毒素类化合物p-x及其制备方法和应用
CN113200994B (zh) * 2021-04-27 2022-05-17 济宁市第一人民医院 鬼臼毒素羧酸酯类衍生物在制备抗肿瘤产品中的应用
CN113214281B (zh) * 2021-05-19 2022-05-17 济宁市第一人民医院 一类苯磺酰胺苯丁酸鬼臼毒素酯类衍生物的合成及在抗癌药物中的应用
CN114028580B (zh) * 2021-09-30 2023-08-08 成都理工大学 一种鬼臼毒素孪药纳米粒的制备方法
CN115212314B (zh) * 2022-06-14 2024-04-30 沈阳药科大学 一种白蛋白结合型抗肿瘤药及其纳米复合物、制备方法和应用

Also Published As

Publication number Publication date
AU2003244727A1 (en) 2003-10-13
WO2003082875A3 (fr) 2004-04-01
WO2003082875A2 (fr) 2003-10-09
FR2837824A1 (fr) 2003-10-03

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Legal Events

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Effective date: 20071130