FR2756490B1 - Methodes de prevention du cancer du sein - Google Patents

Methodes de prevention du cancer du sein

Info

Publication number
FR2756490B1
FR2756490B1 FR9713580A FR9713580A FR2756490B1 FR 2756490 B1 FR2756490 B1 FR 2756490B1 FR 9713580 A FR9713580 A FR 9713580A FR 9713580 A FR9713580 A FR 9713580A FR 2756490 B1 FR2756490 B1 FR 2756490B1
Authority
FR
France
Prior art keywords
methods
breast cancer
preventing breast
preventing
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9713580A
Other languages
English (en)
French (fr)
Other versions
FR2756490A1 (fr
Inventor
Frederic Jay Cohen
Joan Ellen Glusman
Ronald Keith Knickerbocker
Nikolaus Thomas Nickelsen
Teri Janine Scott
Robert Stephen Eckert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27268608&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2756490(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9624800.0A external-priority patent/GB9624800D0/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2756490A1 publication Critical patent/FR2756490A1/fr
Application granted granted Critical
Publication of FR2756490B1 publication Critical patent/FR2756490B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
FR9713580A 1996-10-30 1997-10-29 Methodes de prevention du cancer du sein Expired - Fee Related FR2756490B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2985096P 1996-10-30 1996-10-30
GBGB9624800.0A GB9624800D0 (en) 1996-11-29 1996-11-29 Methods of preventing breast cancer
US4026097P 1997-03-10 1997-03-10

Publications (2)

Publication Number Publication Date
FR2756490A1 FR2756490A1 (fr) 1998-06-05
FR2756490B1 true FR2756490B1 (fr) 2003-06-20

Family

ID=27268608

Family Applications (2)

Application Number Title Priority Date Filing Date
FR9713580A Expired - Fee Related FR2756490B1 (fr) 1996-10-30 1997-10-29 Methodes de prevention du cancer du sein
FR9713579A Expired - Fee Related FR2755014B1 (fr) 1996-10-30 1997-10-29 Ameliorations concernant la prophylaxie du cancer du sein

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR9713579A Expired - Fee Related FR2755014B1 (fr) 1996-10-30 1997-10-29 Ameliorations concernant la prophylaxie du cancer du sein

Country Status (43)

Country Link
US (2) US6303634B1 (OSRAM)
EP (3) EP1369115B1 (OSRAM)
JP (2) JPH10147530A (OSRAM)
CN (2) CN1182591A (OSRAM)
AP (1) AP971A (OSRAM)
AR (2) AR010538A1 (OSRAM)
AT (2) ATE239475T1 (OSRAM)
AU (3) AU5005197A (OSRAM)
BE (2) BE1011381A5 (OSRAM)
BG (1) BG63841B1 (OSRAM)
BR (1) BR9712703A (OSRAM)
CA (2) CA2219377A1 (OSRAM)
CH (2) CH693820A5 (OSRAM)
CZ (2) CZ341297A3 (OSRAM)
DE (2) DE69721692T2 (OSRAM)
DK (2) DK0839532T3 (OSRAM)
EA (2) EA002054B1 (OSRAM)
EE (1) EE03663B1 (OSRAM)
ES (4) ES2135342B1 (OSRAM)
FR (2) FR2756490B1 (OSRAM)
GB (3) GB2318734B (OSRAM)
GE (1) GEP20032910B (OSRAM)
GR (2) GR970100409A (OSRAM)
HU (2) HUP9701778A3 (OSRAM)
IE (2) IE970772A1 (OSRAM)
IL (2) IL122026A0 (OSRAM)
IS (1) IS5035A (OSRAM)
IT (2) ITMI972434A1 (OSRAM)
LU (2) LU90157B1 (OSRAM)
LV (1) LV12353B (OSRAM)
MY (1) MY121623A (OSRAM)
NL (2) NL1007387C2 (OSRAM)
NO (2) NO974973D0 (OSRAM)
NZ (1) NZ329042A (OSRAM)
PT (2) PT839532E (OSRAM)
RO (1) RO120813B1 (OSRAM)
SG (2) SG72765A1 (OSRAM)
SI (3) SI1369115T1 (OSRAM)
SK (1) SK287047B6 (OSRAM)
TR (1) TR199900951T2 (OSRAM)
UA (1) UA46762C2 (OSRAM)
WO (2) WO1998018449A1 (OSRAM)
YU (1) YU42397A (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458811B1 (en) * 1996-03-26 2002-10-01 Eli Lilly And Company Benzothiophenes formulations containing same and methods
GB9624800D0 (en) * 1996-11-29 1997-01-15 Lilly Co Eli Methods of preventing breast cancer
FI109332B (fi) 1998-12-17 2002-07-15 Orion Yhtymae Oyj Toremifeenin liukoisia koostumuksia
FI982733A7 (fi) * 1998-12-17 2000-06-18 Orion Yhtymae Oyj Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia
WO2002094788A1 (en) 2001-05-22 2002-11-28 Eli Lilly And Company 2-substituted 1,2,3,4-tetrahydroquinolines and derivatives thereof, compositions and methods
PT1401446E (pt) 2001-05-22 2005-05-31 Lilly Co Eli Derivados de tetrahidroquinolina para a inibicao de doencas associadas com a privacao de estrogenio ou com uma resposta fisiologica aberrante ao estrogenio endogeno
US20040225200A1 (en) * 2003-05-09 2004-11-11 Edmundson Catherine M. System and method of analyzing the health of a population
GR1005694B (el) * 2005-06-08 2007-10-22 Αλεξης Μιχαηλ Ιστοειδικα αντιοιστρογονα ειδικα για τον αλφα υποδοχεα των οιστρογονων
UA97813C2 (uk) * 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
WO2011099942A1 (en) 2010-02-09 2011-08-18 Silverstone Pharma New addition salts of raloxifene, process for the preparation thereof and use thereof in therapy
CN102973573B (zh) * 2012-11-28 2015-04-08 玉林师范学院 一种人乳腺癌细胞抑制剂及制备方法
CN103830197A (zh) * 2014-03-14 2014-06-04 崔书豪 一种盐酸雷洛昔芬分散片及其制备方法
CN116650484A (zh) * 2023-05-11 2023-08-29 南通大学 一种乳腺癌相关蛋白的抑制剂及其应用
WO2025099483A1 (en) * 2023-11-06 2025-05-15 Centro De Investigación Y De Estudios Avanzados Del I.P.N. Use for raloxifene for the treatment of hepatic cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4656187A (en) * 1981-08-03 1987-04-07 Eli Lilly And Company Treatment of mammary cancer
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
ZA948025B (en) * 1993-10-15 1996-04-15 Lilly Co Eli Methods for treating resistant neoplasms
CA2143263C (en) * 1994-03-02 2002-01-08 Kerry John Hartauer Orally administrable raloxifene formulations
US5478847A (en) * 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
US5604248A (en) * 1994-05-05 1997-02-18 Eli Lilly And Company Method for minimizing the uterotrophic effect of tamoxifen and tamoxifen analogs
US5521214A (en) * 1995-01-25 1996-05-28 Eli Lilly And Company Methods of inhibiting environmental estrogens
US5821254A (en) 1995-02-17 1998-10-13 The United States Of America As Represented By The Department Of Health And Human Services Uses of 9-cis-retinoic acids and derivatives thereof alone or in combination with antineoplastic agents in the prevention or treatment of cancer
EA001257B1 (ru) * 1996-03-26 2000-12-25 Эли Лилли Энд Компани Бензотиофены, содержащие их фармацевтические композиции и способы лечения патологических состояний с их использованием

Also Published As

Publication number Publication date
NO974972D0 (no) 1997-10-28
MY121623A (en) 2006-02-28
DK1369115T3 (da) 2007-01-02
CZ300261B6 (cs) 2009-04-01
CN1182590A (zh) 1998-05-27
ES2271476T3 (es) 2007-04-16
SK287047B6 (sk) 2009-10-07
US20020019418A1 (en) 2002-02-14
EP1369115B1 (en) 2006-09-06
ITMI972434A1 (it) 1999-04-29
NL1007386C2 (nl) 1998-05-14
GB2318734A (en) 1998-05-06
EP0839532B1 (en) 2003-05-07
SI1369115T1 (sl) 2006-12-31
EE03663B1 (et) 2002-04-15
AU5005697A (en) 1998-05-22
WO1998018325A1 (en) 1998-05-07
CA2219070A1 (en) 1998-04-30
CH691847A5 (fr) 2001-11-15
ES2197312T3 (es) 2004-01-01
GB2318733A (en) 1998-05-06
WO1998018449A1 (en) 1998-05-07
EP0839532A1 (en) 1998-05-06
GB9722801D0 (en) 1997-12-24
DE69736644T2 (de) 2007-10-25
CA2219070C (en) 2007-12-18
IE970773A1 (en) 2000-02-09
BE1011381A5 (fr) 1999-08-03
UA46762C2 (uk) 2002-06-17
ITMI972433A1 (it) 1999-04-29
FR2756490A1 (fr) 1998-06-05
AP971A (en) 2001-05-30
GR970100408A (el) 1998-06-30
IL122026A0 (en) 1998-03-10
IT1298470B1 (it) 2000-01-10
ES2135343A1 (es) 1999-10-16
EP0839533A1 (en) 1998-05-06
EA199900431A1 (ru) 1999-10-28
GR1003189B (el) 1999-09-01
SK55999A3 (en) 2000-06-12
SI0839532T1 (en) 2003-10-31
IS5035A (is) 1999-04-27
CZ341297A3 (cs) 1998-05-13
GB2318734B (en) 1999-12-01
BR9712703A (pt) 1999-10-26
NZ329042A (en) 1999-08-30
LU90158B1 (fr) 1998-06-02
MX9708340A (es) 1998-08-30
IL122025A0 (en) 1998-03-10
CH693820A5 (fr) 2004-02-27
AU4364797A (en) 1998-05-07
IE970772A1 (en) 2000-02-09
CN1182591A (zh) 1998-05-27
AP9901494A0 (en) 1999-03-31
PT1369115E (pt) 2006-12-29
SG83672A1 (en) 2001-10-16
AU4364897A (en) 1998-05-07
AR010538A1 (es) 2000-06-28
SI20107A (sl) 2000-06-30
LU90157B1 (fr) 1998-06-02
HUP9701777A3 (en) 1999-07-28
JPH10147529A (ja) 1998-06-02
US6303634B1 (en) 2001-10-16
CA2219377A1 (en) 1998-04-30
DE69721692D1 (de) 2003-06-12
ATE338551T1 (de) 2006-09-15
GB9911557D0 (en) 1999-07-21
ES2135342A1 (es) 1999-10-16
CZ341197A3 (cs) 1998-05-13
HUP9701778A3 (en) 1999-06-28
HK1010495A1 (en) 1999-06-25
DE69721692T2 (de) 2004-03-25
HUP9701778A2 (hu) 1999-01-28
PT839532E (pt) 2003-09-30
YU42397A (sh) 2000-10-30
RO120813B1 (ro) 2006-08-30
AU5005197A (en) 1998-05-22
EE9900162A (et) 1999-12-15
NL1007387C2 (nl) 1998-05-14
JPH10147530A (ja) 1998-06-02
IL122025A (en) 2003-01-12
AU731388B2 (en) 2001-03-29
BG103369A (en) 2000-05-31
GR970100409A (el) 1998-06-30
DK0839532T3 (da) 2003-08-25
FR2755014A1 (fr) 1998-04-30
AR013864A1 (es) 2001-01-31
DE69736644D1 (de) 2006-10-19
HU9701777D0 (en) 1997-12-29
HU9701778D0 (en) 1997-12-29
HUP9701777A2 (hu) 1999-06-28
EA002054B1 (ru) 2001-12-24
NO974973D0 (no) 1997-10-28
BE1011382A5 (fr) 1999-08-03
LV12353B (en) 2000-02-20
FR2755014B1 (fr) 1999-02-05
ATE239475T1 (de) 2003-05-15
EA200100716A1 (ru) 2002-06-27
GEP20032910B (en) 2003-03-25
LV12353A (lv) 1999-10-20
NO322468B1 (no) 2006-10-09
SG72765A1 (en) 2000-05-23
GB9722796D0 (en) 1997-12-24
MX9708341A (es) 1998-08-30
ES2135342B1 (es) 2000-05-16
BG63841B1 (bg) 2003-03-31
EA006083B1 (ru) 2005-08-25
EP1369115A1 (en) 2003-12-10
TR199900951T2 (xx) 1999-07-21
NO974972L (no) 1998-05-04

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Legal Events

Date Code Title Description
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Effective date: 20090630