FR2596062B1 - Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains - Google Patents

Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains

Info

Publication number
FR2596062B1
FR2596062B1 FR878702304A FR8702304A FR2596062B1 FR 2596062 B1 FR2596062 B1 FR 2596062B1 FR 878702304 A FR878702304 A FR 878702304A FR 8702304 A FR8702304 A FR 8702304A FR 2596062 B1 FR2596062 B1 FR 2596062B1
Authority
FR
France
Prior art keywords
human
antigen
certain
monoclonal antibodies
small cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR878702304A
Other languages
English (en)
French (fr)
Other versions
FR2596062A1 (fr
Inventor
Karl Erik Hellstrom
Joseph P Brown
Ingegerd Hellstrom
Hans Marquard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of FR2596062A1 publication Critical patent/FR2596062A1/fr
Application granted granted Critical
Publication of FR2596062B1 publication Critical patent/FR2596062B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • G01N33/5752—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Metal Extraction Processes (AREA)
  • Wire Processing (AREA)
FR878702304A 1986-02-26 1987-02-23 Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains Expired - Fee Related FR2596062B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/834,172 US5185432A (en) 1986-02-26 1986-02-26 Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas

Publications (2)

Publication Number Publication Date
FR2596062A1 FR2596062A1 (fr) 1987-09-25
FR2596062B1 true FR2596062B1 (fr) 1990-06-08

Family

ID=25266276

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878702304A Expired - Fee Related FR2596062B1 (fr) 1986-02-26 1987-02-23 Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains

Country Status (28)

Country Link
US (1) US5185432A (cg-RX-API-DMAC10.html)
JP (1) JPS62220197A (cg-RX-API-DMAC10.html)
KR (2) KR870008026A (cg-RX-API-DMAC10.html)
CN (1) CN87100927A (cg-RX-API-DMAC10.html)
AT (1) AT400577B (cg-RX-API-DMAC10.html)
AU (1) AU612967B2 (cg-RX-API-DMAC10.html)
BE (1) BE1000611A5 (cg-RX-API-DMAC10.html)
CA (1) CA1312025C (cg-RX-API-DMAC10.html)
CH (1) CH675880A5 (cg-RX-API-DMAC10.html)
DD (2) DD276165A5 (cg-RX-API-DMAC10.html)
DE (1) DE3705276A1 (cg-RX-API-DMAC10.html)
DK (1) DK98187A (cg-RX-API-DMAC10.html)
ES (1) ES2004245A6 (cg-RX-API-DMAC10.html)
FI (1) FI870764A7 (cg-RX-API-DMAC10.html)
FR (1) FR2596062B1 (cg-RX-API-DMAC10.html)
GB (1) GB2186885B (cg-RX-API-DMAC10.html)
GR (1) GR870294B (cg-RX-API-DMAC10.html)
IE (1) IE60286B1 (cg-RX-API-DMAC10.html)
IT (1) IT1203511B (cg-RX-API-DMAC10.html)
LU (1) LU86786A1 (cg-RX-API-DMAC10.html)
NL (1) NL8700415A (cg-RX-API-DMAC10.html)
NO (1) NO174719C (cg-RX-API-DMAC10.html)
NZ (1) NZ219338A (cg-RX-API-DMAC10.html)
OA (1) OA08485A (cg-RX-API-DMAC10.html)
PT (1) PT84370B (cg-RX-API-DMAC10.html)
SE (2) SE467988B (cg-RX-API-DMAC10.html)
YU (1) YU46189B (cg-RX-API-DMAC10.html)
ZA (1) ZA869494B (cg-RX-API-DMAC10.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung
JPH0813840B2 (ja) * 1987-03-31 1996-02-14 協和醗酵工業株式会社 抗ヒト肺腺癌単クロ−ン性抗体
US5134075A (en) * 1989-02-17 1992-07-28 Oncogen Limited Partnership Monoclonal antibody to novel antigen associated with human tumors
US5171665A (en) * 1989-04-17 1992-12-15 Oncogen Monoclonal antibody to novel antigen associated with human tumors
US5342774A (en) * 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5589579A (en) * 1994-07-19 1996-12-31 Cytoclonal Pharmaceutics, Inc. Gene sequence and probe for a marker of non-small cell lung carinoma
ES2246522T3 (es) 1997-03-03 2006-02-16 Amersham Biosciences Uk Ltd Extraccion celular in-situ y metodo analitico.
DE19725133A1 (de) * 1997-06-13 1998-12-17 Micromet Ges Fuer Biomedizinis Nachweis von seltenen Zellen
US20050089918A1 (en) * 1998-02-23 2005-04-28 Amersham Biosciences Uk Limited In-situ cell extraction and assay method
US6117981A (en) * 1999-06-03 2000-09-12 Cytoclonal Pharmaceutics, Inc. Hybridomas for lung cancer marker and monoclonal antibodies thereof
EP1212344A4 (en) * 1999-09-03 2004-08-04 Human Genome Sciences Inc POLYNUCLEOTIDES, POLYPEPTIDES AND ANTIBODIES OF THE TYPE B7
WO2001094413A2 (en) 2000-06-06 2001-12-13 Bristol-Myers Squibb Company B7-related nucleic acids and polypeptides and their uses for immunomodulation
TWI317285B (en) * 2000-07-28 2009-11-21 Dainippon Sumitomo Pharma Co New use and kit for remedies for cancer
CN101724072B (zh) * 2008-10-27 2013-10-09 谷为岳 一种抗肿瘤的单克隆抗体的序列及应用
GB0916686D0 (en) * 2009-09-23 2009-11-04 Univ Manchester Metropolitan Treatment of cancer
LT2542256T (lt) 2010-03-04 2019-10-25 Macrogenics Inc Su b7-h3 reaguojantys antikūnai, jų imunologiškai aktyvūs fragmentai ir jų naudojimas
PH12012501751A1 (en) 2010-03-04 2012-11-12 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
WO2012036094A1 (ja) * 2010-09-17 2012-03-22 独立行政法人産業技術総合研究所 肺癌鑑別マーカー
CN102391992B (zh) * 2011-11-03 2012-08-29 潘世扬 抗人非小细胞肺癌单克隆抗体及其应用
GEAP202214922A (en) 2016-04-15 2022-02-10 Macrogenics Inc Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof
CN111662371B (zh) * 2020-04-30 2023-07-04 美康生物科技股份有限公司 细胞角蛋白19片段抗原及其制备方法和应用
CN112300284B (zh) * 2020-12-29 2021-04-06 慈达(广州)生物技术有限公司 核酸筛选结合抗体检测用于癌症检测中的用途及其制备的试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569788A (en) * 1983-05-18 1986-02-11 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies against non small cell lung cancer
IL76877A (en) * 1984-11-02 1991-11-21 Oncogen Diagnostic method for the determination of human non-small cell lung carcinomas employing novel monoclonal antibodies and compositions containing said antibodies
ZA858371B (en) * 1984-11-02 1987-03-25 Oncogen Monoclonal antibodies for human non-small cell lung carcinomas

Also Published As

Publication number Publication date
DE3705276A1 (de) 1987-08-27
NO174719B (no) 1994-03-14
NZ219338A (en) 1991-11-26
KR880010438A (ko) 1988-10-08
IT8719491A0 (it) 1987-02-25
FI870764A0 (fi) 1987-02-23
DK98187D0 (da) 1987-02-25
FR2596062A1 (fr) 1987-09-25
US5185432A (en) 1993-02-09
SE467988B (sv) 1992-10-12
GB2186885A (en) 1987-08-26
CN87100927A (zh) 1988-10-05
NL8700415A (nl) 1987-09-16
CA1312025C (en) 1992-12-29
KR870008026A (ko) 1987-09-23
PT84370A (en) 1987-03-01
DK98187A (da) 1987-08-27
IE870487L (en) 1987-08-26
DD266028A5 (de) 1989-03-22
SE8700805L (sv) 1987-10-22
DD276165A5 (de) 1990-02-14
YU25787A (en) 1990-12-31
GB8703700D0 (en) 1987-03-25
GB2186885B (en) 1990-10-03
ATA43587A (de) 1995-06-15
JPS62220197A (ja) 1987-09-28
GR870294B (en) 1987-06-30
IE60286B1 (en) 1994-06-29
PT84370B (pt) 1989-11-10
ES2004245A6 (es) 1988-12-16
SE9201529D0 (sv) 1992-05-14
KR900006338B1 (ko) 1990-08-28
IT1203511B (it) 1989-02-15
YU46189B (sh) 1993-05-28
ZA869494B (en) 1987-10-28
AU6927287A (en) 1987-08-27
FI870764A7 (fi) 1987-08-27
OA08485A (fr) 1988-07-29
BE1000611A5 (fr) 1989-02-21
SE9201529A0 (sv) 1992-05-14
AT400577B (de) 1996-01-25
CH675880A5 (cg-RX-API-DMAC10.html) 1990-11-15
NO870770D0 (no) 1987-02-25
SE8700805D0 (sv) 1987-02-25
LU86786A1 (fr) 1987-09-15
NO870770L (no) 1987-08-27
NO174719C (no) 1994-06-22
AU612967B2 (en) 1991-07-25

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Legal Events

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ST Notification of lapse