FR2535609A1 - Medicament a action antitumorale a base de polyhexamethyleneguanidine - Google Patents

Medicament a action antitumorale a base de polyhexamethyleneguanidine Download PDF

Info

Publication number
FR2535609A1
FR2535609A1 FR8218494A FR8218494A FR2535609A1 FR 2535609 A1 FR2535609 A1 FR 2535609A1 FR 8218494 A FR8218494 A FR 8218494A FR 8218494 A FR8218494 A FR 8218494A FR 2535609 A1 FR2535609 A1 FR 2535609A1
Authority
FR
France
Prior art keywords
cancer
product
polyhexamethyleneguanidine
tumor
action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8218494A
Other languages
English (en)
French (fr)
Other versions
FR2535609B1 (ja
Inventor
I Z Lulle
M J Lidak
R A Paegle
A A Zidermane
I M Kravchenko
A P Gilev
T I Kagan
P A Gembitsky
B Z Simkhovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST ORGANICHESKOGO SINTEZA AK
Original Assignee
INST ORGANICHESKOGO SINTEZA AK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST ORGANICHESKOGO SINTEZA AK filed Critical INST ORGANICHESKOGO SINTEZA AK
Publication of FR2535609A1 publication Critical patent/FR2535609A1/fr
Application granted granted Critical
Publication of FR2535609B1 publication Critical patent/FR2535609B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
FR8218494A 1982-06-21 1982-11-04 Medicament a action antitumorale a base de polyhexamethyleneguanidine Granted FR2535609A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SU1982/000020 WO1984000105A1 (en) 1982-06-21 1982-06-21 Medicinal preparation having antitumoral effect

Publications (2)

Publication Number Publication Date
FR2535609A1 true FR2535609A1 (fr) 1984-05-11
FR2535609B1 FR2535609B1 (ja) 1985-03-15

Family

ID=21616776

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8218494A Granted FR2535609A1 (fr) 1982-06-21 1982-11-04 Medicament a action antitumorale a base de polyhexamethyleneguanidine

Country Status (9)

Country Link
JP (1) JPS59501110A (ja)
CA (1) CA1194802A (ja)
CH (1) CH660964A5 (ja)
DE (1) DE3249514T1 (ja)
FR (1) FR2535609A1 (ja)
GB (1) GB2134783B (ja)
NL (1) NL8220420A (ja)
SE (1) SE8400453L (ja)
WO (1) WO1984000105A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1110948A2 (en) * 1999-12-20 2001-06-27 SK Corporation Polyhexamethyleneguanidine phosphate powder, method of making the same and antimicrobial resin containing the same

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344846A (en) * 1992-12-30 1994-09-06 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
DE19628641C2 (de) * 1996-07-16 1998-12-17 Fresenius Ag Verwendung von PHMB zur Behandlung von Tumorerkrankungen
KR100725004B1 (ko) * 1999-12-24 2007-06-04 에스케이 주식회사 살균소독제 조성물 및 이의 사용방법
AT505312A1 (de) 2007-05-15 2008-12-15 Recticel Schlafkomfort Gmbh Sc Polyurethan-werkstoff mit einer bioziden ausrüstung

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5341426A (en) * 1976-09-27 1978-04-14 Asahi Chem Ind Co Ltd Fungicidal and bactericidal agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824288A (en) * 1961-06-09 1974-07-16 Hoffmann La Roche Substituted hydrazine derivatives and process for the manufacture thereof
BR6457241D0 (pt) * 1963-12-23 1973-06-26 Rohm & Haas Processo para a preparacao de t-octil-guanidinas
GB1492678A (en) * 1975-08-11 1977-11-23 Ici Ltd Guanidine derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5341426A (en) * 1976-09-27 1978-04-14 Asahi Chem Ind Co Ltd Fungicidal and bactericidal agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 89, no. 19, 6 novembre 1978, page 175, résumé no. 158758a COLUMBUS OHIO (US) & JP - A - 78 41 426 (ASAHI CHEMICAL INDUSTRY CO. LTD.)(14-04-1978) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1110948A2 (en) * 1999-12-20 2001-06-27 SK Corporation Polyhexamethyleneguanidine phosphate powder, method of making the same and antimicrobial resin containing the same
EP1110948A3 (en) * 1999-12-20 2002-01-09 SK Corporation Polyhexamethyleneguanidine phosphate powder, method of making the same and antimicrobial resin containing the same

Also Published As

Publication number Publication date
SE437931B (sv) 1985-03-25
DE3249514T1 (de) 1984-05-17
GB2134783A (en) 1984-08-22
CA1194802A (en) 1985-10-08
SE8400453D0 (sv) 1984-01-30
CH660964A5 (de) 1987-06-30
WO1984000105A1 (en) 1984-01-19
SE8400453L (sv) 1985-03-25
GB2134783B (en) 1985-10-30
FR2535609B1 (ja) 1985-03-15
GB8403257D0 (en) 1984-03-14
NL8220420A (nl) 1984-05-01
JPS59501110A (ja) 1984-06-28

Similar Documents

Publication Publication Date Title
WO2017162108A1 (zh) 一种柱芳烃类复合物、其制备方法、药物组合物和用途
KR101888779B1 (ko) Ampk 활성을 증진시킬 수 있는 약물을 제조하기 위한 이소퀴놀린 알칼로이드 유도체의 용도
JP6209579B2 (ja) 補助化療薬品とされる医薬組成物その用途
CA2522980A1 (en) Water soluble wortmannin derivatives
FR2535609A1 (fr) Medicament a action antitumorale a base de polyhexamethyleneguanidine
JP2019531353A (ja) 重水素化化合物及びその医薬的用途
FR2601678A1 (fr) Peptides comprenant la sequence seryl-aspartyl-lysyl-prolyle, procede pour l'extraction du tetrapeptide correspondant, et applications, notamment a la protection de la moelle osseuse au cours de traitements anticancereux par la chimiotherapie
FR2662940A1 (fr) Utilisation de derives de la tetrahydro isoquinoleine pour la preparation de medicaments anti-tumoraux, application a titre de medicaments de derives de la tetrahydro isoquinoleine et produits derives de cette structure.
RU2084449C1 (ru) 1-бензил-2-оксотриптамин гидрохлорид и его производные, обладающие гепатозащитной активностью
FR3002451A1 (fr) Heterocycles phosphores analogues de sucres a activite antimetastatique
JP7485311B2 (ja) がん細胞増殖抑制剤及びがん細胞増殖抑制効果増強剤
WO2021120874A1 (zh) 一种基于n-(3-羟基吡啶-2-羰基)甘氨酸的抗肿瘤药物增敏剂及其应用
KR100360350B1 (ko) 어포토시스억제제
EP0092226B1 (en) Extract of plants of the family of hypoxidaceae for treatment of cancer
CN104326937B (zh) 抗肿瘤化合物及其医药用途
US20100256230A1 (en) 1-butane acid derivatives, pharmaceutical compositions containing said derivatives and the use thereof
RU2675237C1 (ru) Соединение (6-{ [(1S)-1(5-фтор-4-оксо-3-фенил-3,4-дигидрохиназолин-2-ил)пропил]амино} -9Н-пурин-9-ил)метилацетат как ингибитор p110δ - дельта-изоформы фосфоинозитид-3-киназы (PI3K), способы его получения (варианты) и применения
CN112915087B (zh) 一种基于5-羧基-8-羟基喹啉的抗肿瘤药物增敏剂及其应用
CN117731654B (zh) Jjh201601在初发性脑胶质瘤和复发性脑胶质瘤治疗中的新用途
CN115286574B (zh) Blvrb酶功能抑制剂及其制备方法和用途
KR19990034285A (ko) 항암활성을 갖는 육두구 추출물
BE1028852B1 (fr) PRODROGUE DU 5α-hydroxy-6β-[2-(1H-imidazol-4-yl) éthylamino]cholestan-3β-ol ET COMPOSITIONS PHARMACEUTIQUES LE COMPRENANT POUR UTILISATION DANS LE TRAITEMENT DU CANCER
CN108904503B (zh) 6-氯-5-硝基-2,4-二氨基嘧啶在治疗慢性粒细胞白血病药物中的应用
RU2623034C1 (ru) Противоопухолевое средство
JP2002521341A (ja) 抗癌および抗炎症効果を有する牛糞抽出物およびその製造方法

Legal Events

Date Code Title Description
ST Notification of lapse