FR2500751A1 - Compositions pharmaceutiques anti-inflammatoires topiques a base de sels d'acides carboxyliques, nouveaux sels d'acides carboxyliques et leur preparation - Google Patents
Compositions pharmaceutiques anti-inflammatoires topiques a base de sels d'acides carboxyliques, nouveaux sels d'acides carboxyliques et leur preparation Download PDFInfo
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- FR2500751A1 FR2500751A1 FR8103932A FR8103932A FR2500751A1 FR 2500751 A1 FR2500751 A1 FR 2500751A1 FR 8103932 A FR8103932 A FR 8103932A FR 8103932 A FR8103932 A FR 8103932A FR 2500751 A1 FR2500751 A1 FR 2500751A1
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- 235000010944 ethyl methyl cellulose Nutrition 0.000 description 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 1
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- 239000004744 fabric Substances 0.000 description 1
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- 239000008273 gelatin Substances 0.000 description 1
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- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
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- 238000010438 heat treatment Methods 0.000 description 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 150000003840 hydrochlorides Chemical class 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
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- 239000012442 inert solvent Substances 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
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- 230000001333 moisturizer Effects 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- 235000010935 mono and diglycerides of fatty acids Nutrition 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- YNAVUWVOSKDBBP-UHFFFAOYSA-O morpholinium Chemical compound [H+].C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-O 0.000 description 1
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- 229940105132 myristate Drugs 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
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- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 235000015927 pasta Nutrition 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 125000004817 pentamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical group CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- NWZBFJYXRGSRGD-UHFFFAOYSA-M sodium;octadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOS([O-])(=O)=O NWZBFJYXRGSRGD-UHFFFAOYSA-M 0.000 description 1
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- 235000015096 spirit Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-O triethanolammonium Chemical compound OCC[NH+](CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-O 0.000 description 1
- JSPLKZUTYZBBKA-UHFFFAOYSA-N trioxidane Chemical compound OOO JSPLKZUTYZBBKA-UHFFFAOYSA-N 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8105822A GB2093693B (en) | 1981-02-24 | 1981-02-24 | Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids novel carboxylic acid salts and the production thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2500751A1 true FR2500751A1 (fr) | 1982-09-03 |
| FR2500751B1 FR2500751B1 (en, 2012) | 1984-12-28 |
Family
ID=10519933
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8103932A Granted FR2500751A1 (fr) | 1981-02-24 | 1981-02-27 | Compositions pharmaceutiques anti-inflammatoires topiques a base de sels d'acides carboxyliques, nouveaux sels d'acides carboxyliques et leur preparation |
| FR8119055A Granted FR2514348A1 (fr) | 1981-02-24 | 1981-10-09 | Nouveaux sels d'acides carboxyliques, procede pour leur preparation et compositions pharmaceutiques les contenant |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8119055A Granted FR2514348A1 (fr) | 1981-02-24 | 1981-10-09 | Nouveaux sels d'acides carboxyliques, procede pour leur preparation et compositions pharmaceutiques les contenant |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US4407824A (en, 2012) |
| AT (1) | AT370721B (en, 2012) |
| CA (1) | CA1180008A (en, 2012) |
| CY (2) | CY1443A (en, 2012) |
| FR (2) | FR2500751A1 (en, 2012) |
| GB (2) | GB2093693B (en, 2012) |
| HK (1) | HK83888A (en, 2012) |
| KE (1) | KE3820A (en, 2012) |
| LU (1) | LU83945A1 (en, 2012) |
| NL (1) | NL193216C (en, 2012) |
| SE (2) | SE448088B (en, 2012) |
| SG (1) | SG33388G (en, 2012) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2499980A1 (fr) * | 1981-02-16 | 1982-08-20 | Ciba Geigy Ag | Le (o-(2,6-dichloranilino))-phenylacetate de n-methyl-d-glucammonium, son obtention et les preparations pharmaceutiques le contenant |
| EP0095952A3 (fr) * | 1982-05-04 | 1984-03-28 | Emile Dr. Bouchara | Nouveau sel d'indométacine, son procédé de préparation et les compositions pharmaceutiques en renfermant |
| EP0147476A1 (en) * | 1983-12-08 | 1985-07-10 | Toko Yakuhin Industry Co., Ltd. | Gel preparations for external application |
| FR2569690A1 (fr) * | 1984-09-06 | 1986-03-07 | Sigma Tau Ind Farmaceuti | Sel de d,l-lysine de l'acide 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetique, son procede de preparation et compositions pharmaceutiques le contenant |
| GB2231570A (en) * | 1989-05-12 | 1990-11-21 | American Home Prod | Amine salts of a naphthalenepropionic acid derivative |
| EP0472501A3 (en) * | 1990-08-23 | 1993-02-24 | Ciba-Geigy Ag | Codeinsalt of a substituted carbonacid, process of its preparation, its use and pharmaceutical preparations |
| EP0621263A3 (en) * | 1993-04-23 | 1995-02-15 | Teikoku Seiyaku Kk | Anti-inflammatory and analgesic external plaster preparation. |
| WO1996000716A1 (en) * | 1994-06-29 | 1996-01-11 | Ciba-Geigy Ag | New salts of 2-[(2,6-dichlorophenyl)amine]phenylacetoxyacetic acid with organic basic cations |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4437053A (en) * | 1982-05-10 | 1984-03-13 | Diasonics (Nmr) Inc. | Gradient power supply |
| CH655656B (en, 2012) * | 1982-10-07 | 1986-05-15 | ||
| ES8407042A1 (es) * | 1982-10-08 | 1984-09-01 | Espinos & Bofill Lab Sa | Procedimiento para la obtencion de un nuevo derivado del sulpiride. |
| JPS59137408A (ja) * | 1983-01-27 | 1984-08-07 | Taisho Pharmaceut Co Ltd | 軟膏 |
| JPS59139315A (ja) * | 1983-01-31 | 1984-08-10 | Taisho Pharmaceut Co Ltd | クリ−ム剤 |
| CH643138A5 (de) * | 1983-08-29 | 1984-05-30 | Mepha Ag | Indomethacin enthaltende, gelartige salbe. |
| US4670254A (en) * | 1983-12-09 | 1987-06-02 | Toko Yakuhin Industry Co., Ltd. | Gel preparations for topical application of diclofenac sodium |
| DE3423589A1 (de) * | 1984-06-27 | 1986-01-09 | Wella Ag, 6100 Darmstadt | Oxidationshaarfaerbemittel auf basis einer niedrigviskosen traegermasse |
| CA1265288A (en) * | 1984-11-22 | 1990-01-30 | E. I. Du Pont De Nemours And Company | Curable fluoroelastomer composition |
| US4980084A (en) * | 1985-09-11 | 1990-12-25 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Water rinsable petroleum jelly compositions |
| US4690774A (en) * | 1985-09-11 | 1987-09-01 | Chesebrough Pond's Inc. | Novel translucent water in oil emulsions |
| US4832858A (en) * | 1987-02-19 | 1989-05-23 | Chesebrough-Pond's Inc. | Water dispersible petroleum jelly compositions |
| US5444076A (en) * | 1990-11-26 | 1995-08-22 | Roemmers S.A.I.C.F. | Pharmaceutical preparation for topical application |
| AU2259692A (en) * | 1991-07-03 | 1993-02-11 | Sano Corporation | Composition and method for transdermal delivery of diclofenac |
| US6117907A (en) * | 1993-04-14 | 2000-09-12 | Sher; Neal A. | Topical treatment of ocular pain after corneal surgery |
| FI100692B (fi) * | 1994-05-24 | 1998-02-13 | Leiras Oy | Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä |
| RU2128989C1 (ru) * | 1997-03-05 | 1999-04-20 | Закрытое акционерное общество "Химмедсинтез" | Композиция антимикробного, противовоспалительного и регенерационного действия |
| US20030060657A1 (en) * | 1998-04-28 | 2003-03-27 | Russinsky Limited | Process for the preparation of Aceclofenac |
| RU2177314C2 (ru) * | 2000-03-22 | 2001-12-27 | Кривошеин Юрий Семенович | Состав с антисептическими, репаративными и болеутоляющими свойствами |
| TWI290464B (en) | 2000-09-01 | 2007-12-01 | Novartis Consumer Health Sa | Treatment of burns |
| DE10114561A1 (de) * | 2001-03-24 | 2002-09-26 | Wella Ag | Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern |
| ITMI20020986A1 (it) * | 2002-05-10 | 2003-11-10 | Acraf | Composizione a base di diclofenac per il trattamento topico di affezioni del cavo orofaringeo |
| AR042206A1 (es) | 2002-11-26 | 2005-06-15 | Novartis Ag | Acidos fenilaceticos y derivados |
| ITMI20030269A1 (it) * | 2003-02-14 | 2004-08-15 | Advance Holdings Ltd | Sale di cetilpiridino di un agente antiinfiammatorio |
| FR2854802B1 (fr) * | 2003-05-12 | 2005-06-24 | Galderma Res & Dev | Procede de preparation d'une formulation contenant un principe actif microdose |
| EP2055298A1 (en) | 2007-10-30 | 2009-05-06 | Novartis AG | Topical composition |
| US11000495B2 (en) | 2014-09-10 | 2021-05-11 | GSK Consumer Healthcare S.A. | Topical diclofenac sodium compositions |
| CN116143647A (zh) * | 2023-03-03 | 2023-05-23 | 长沙晶易医药科技股份有限公司 | 双氯芬酸二乙胺的新晶型及其制备方法 |
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| FR2395251A1 (fr) * | 1977-06-23 | 1979-01-19 | Asahi Chemical Ind | Acide phenylglycolique substitue, sels et esters pharmaceutiquement acceptables de celui-ci et procedes de preparation |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2499980A1 (fr) * | 1981-02-16 | 1982-08-20 | Ciba Geigy Ag | Le (o-(2,6-dichloranilino))-phenylacetate de n-methyl-d-glucammonium, son obtention et les preparations pharmaceutiques le contenant |
| EP0095952A3 (fr) * | 1982-05-04 | 1984-03-28 | Emile Dr. Bouchara | Nouveau sel d'indométacine, son procédé de préparation et les compositions pharmaceutiques en renfermant |
| EP0147476A1 (en) * | 1983-12-08 | 1985-07-10 | Toko Yakuhin Industry Co., Ltd. | Gel preparations for external application |
| FR2569690A1 (fr) * | 1984-09-06 | 1986-03-07 | Sigma Tau Ind Farmaceuti | Sel de d,l-lysine de l'acide 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetique, son procede de preparation et compositions pharmaceutiques le contenant |
| GB2231570A (en) * | 1989-05-12 | 1990-11-21 | American Home Prod | Amine salts of a naphthalenepropionic acid derivative |
| EP0396839A3 (en) * | 1989-05-12 | 1991-06-05 | American Home Products Corporation | Naphthalenepropionic acid salts |
| GB2231570B (en) * | 1989-05-12 | 1992-05-20 | American Home Prod | Naphthalenepropionic acid salts |
| EP0472501A3 (en) * | 1990-08-23 | 1993-02-24 | Ciba-Geigy Ag | Codeinsalt of a substituted carbonacid, process of its preparation, its use and pharmaceutical preparations |
| EP0621263A3 (en) * | 1993-04-23 | 1995-02-15 | Teikoku Seiyaku Kk | Anti-inflammatory and analgesic external plaster preparation. |
| US5607690A (en) * | 1993-04-23 | 1997-03-04 | Teikoku Seiyaku Co., Ltd. | External anti-inflammatory and analgesic plaster preparation |
| WO1996000716A1 (en) * | 1994-06-29 | 1996-01-11 | Ciba-Geigy Ag | New salts of 2-[(2,6-dichlorophenyl)amine]phenylacetoxyacetic acid with organic basic cations |
| US5708024A (en) * | 1994-06-29 | 1998-01-13 | Novartis Corporation | Salts of 2- (2,6-dichlorophenyl)amine!phenylacetoxyacetic acid with organic basic cations |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2143528B (en) | 1985-10-02 |
| SE8203228L (sv) | 1982-08-18 |
| GB2093693B (en) | 1985-10-02 |
| SG33388G (en) | 1988-09-30 |
| CY1444A (en) | 1989-03-10 |
| FR2500751B1 (en, 2012) | 1984-12-28 |
| ATA70981A (de) | 1982-09-15 |
| FR2514348A1 (fr) | 1983-04-15 |
| KE3820A (en) | 1988-09-09 |
| US4407824A (en) | 1983-10-04 |
| CA1180008A (en) | 1984-12-27 |
| US4619926A (en) | 1986-10-28 |
| FR2514348B1 (en, 2012) | 1984-12-14 |
| NL8100917A (nl) | 1982-09-16 |
| AT370721B (de) | 1983-04-25 |
| NL193216B (nl) | 1998-11-02 |
| HK83888A (en) | 1988-10-21 |
| US4551475A (en) | 1985-11-05 |
| GB2143528A (en) | 1985-02-13 |
| GB8418021D0 (en) | 1984-08-22 |
| NL193216C (nl) | 1999-03-03 |
| LU83945A1 (de) | 1982-12-13 |
| SE8101064L (sv) | 1982-08-18 |
| CY1443A (en) | 1989-03-10 |
| GB2093693A (en) | 1982-09-08 |
| US4784808A (en) | 1988-11-15 |
| SE448088B (sv) | 1987-01-19 |
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