FR2488258B1 - - Google Patents

Info

Publication number
FR2488258B1
FR2488258B1 FR8115520A FR8115520A FR2488258B1 FR 2488258 B1 FR2488258 B1 FR 2488258B1 FR 8115520 A FR8115520 A FR 8115520A FR 8115520 A FR8115520 A FR 8115520A FR 2488258 B1 FR2488258 B1 FR 2488258B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8115520A
Other languages
French (fr)
Other versions
FR2488258A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FR2488258A1 publication Critical patent/FR2488258A1/fr
Application granted granted Critical
Publication of FR2488258B1 publication Critical patent/FR2488258B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8115520A 1980-08-11 1981-08-11 Acide 7-beta-(alpha-syn-methoxyimino-alpha - (2-aminothiazol-4-yl) - acetamino)-3-((1,2,3-thiadiazol-5-ylthio) methyl)-3-cepheme-4-carboxylique et derives alkyliques en c1-c6 de celui-ci, compositions contenant ces composes et leurs applications Granted FR2488258A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17688980A 1980-08-11 1980-08-11
US06/281,438 US4399132A (en) 1980-08-11 1981-07-08 7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof

Publications (2)

Publication Number Publication Date
FR2488258A1 FR2488258A1 (fr) 1982-02-12
FR2488258B1 true FR2488258B1 (da) 1984-08-24

Family

ID=26872715

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8115520A Granted FR2488258A1 (fr) 1980-08-11 1981-08-11 Acide 7-beta-(alpha-syn-methoxyimino-alpha - (2-aminothiazol-4-yl) - acetamino)-3-((1,2,3-thiadiazol-5-ylthio) methyl)-3-cepheme-4-carboxylique et derives alkyliques en c1-c6 de celui-ci, compositions contenant ces composes et leurs applications

Country Status (25)

Country Link
US (1) US4399132A (da)
JP (1) JPS5759895A (da)
KR (1) KR840002163B1 (da)
AR (1) AR228869A1 (da)
AT (1) AT389639B (da)
AU (1) AU545895B2 (da)
BE (1) BE889913A (da)
CA (1) CA1175417A (da)
CH (1) CH648561A5 (da)
DD (1) DD202164A5 (da)
DE (1) DE3130404A1 (da)
DK (1) DK155945C (da)
FI (1) FI74020C (da)
FR (1) FR2488258A1 (da)
GB (1) GB2083461B (da)
GR (1) GR75676B (da)
HK (1) HK52089A (da)
HU (1) HU185644B (da)
IE (1) IE51486B1 (da)
IL (1) IL63531A (da)
NL (1) NL8103751A (da)
NO (1) NO161566C (da)
NZ (1) NZ197965A (da)
PL (1) PL131457B1 (da)
SE (1) SE452324B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60120886A (ja) * 1983-12-02 1985-06-28 Takeda Chem Ind Ltd セフェムカルボン酸のナトリウム塩の結晶
US4914091A (en) * 1984-04-02 1990-04-03 American Cyanamid Company Esters of cephalosporin derivitives
EP0238060B1 (en) 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
EP0252473A3 (en) * 1986-07-08 1989-07-05 American Cyanamid Company 7 beta-(substituted) amino-3-substituted cephalosporanic acids and esters
US4927922A (en) * 1986-07-08 1990-05-22 American Cyanamid Company 7β-(substituted)amino-3-substituted cephalosporanic acids and esters
EP0257275A3 (en) * 1986-07-28 1990-05-23 American Cyanamid Company Cephalosporin and penicillin derivatives
US5066799A (en) * 1986-07-28 1991-11-19 American Cyanamid Company Intermediates for the preparation of aminothiazoloximino cephalosporins
JPH01230547A (ja) * 1988-01-14 1989-09-14 Takeda Chem Ind Ltd ３−オキソ酪酸第三ブチルの製造法及びその用途
AT394196B (de) * 1990-01-22 1992-02-10 Biochemie Gmbh (6r,7r)-7-((2-(2-amino-4-thiazolyl) -2oxoacetamido)-3-(1,2,3-thiadiazol-5-yl)thiomethyl-3-cephem-4-carbons|urenitrat
CN105646538B (zh) * 2016-03-09 2018-04-24 上海宁瑞生化技术有限公司 一种头孢唑南的制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
JPS597717B2 (ja) * 1976-09-08 1984-02-20 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2856404A1 (de) * 1978-12-28 1980-07-17 Dynamit Nobel Ag 1,2,3-thiadiazol-5-yl-thioglycolsaeure, deren derivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
SE8104771L (sv) 1982-02-12
FI812470L (fi) 1982-02-12
PL232568A1 (en) 1983-06-06
AU545895B2 (en) 1985-08-08
BE889913A (fr) 1982-02-10
IL63531A0 (en) 1981-11-30
DD202164A5 (de) 1983-08-31
FR2488258A1 (fr) 1982-02-12
IE51486B1 (en) 1987-01-07
KR830006311A (ko) 1983-09-20
NO812701L (no) 1982-02-12
PL131457B1 (en) 1984-11-30
GB2083461A (en) 1982-03-24
DK155945B (da) 1989-06-05
HK52089A (en) 1989-07-07
IL63531A (en) 1985-07-31
JPS5759895A (en) 1982-04-10
JPS6141517B2 (da) 1986-09-16
NO161566B (no) 1989-05-22
KR840002163B1 (ko) 1984-11-24
AU7384881A (en) 1982-02-18
DE3130404C2 (da) 1990-07-19
AR228869A1 (es) 1983-04-29
HU185644B (en) 1985-03-28
CH648561A5 (da) 1985-03-29
US4399132A (en) 1983-08-16
DK355081A (da) 1982-02-12
ATA307683A (de) 1989-06-15
CA1175417A (en) 1984-10-02
GB2083461B (en) 1984-04-11
AT389639B (de) 1990-01-10
DE3130404A1 (de) 1982-06-16
DK155945C (da) 1989-12-04
NL8103751A (nl) 1982-03-01
FI74020C (fi) 1987-12-10
GR75676B (da) 1984-08-02
NO161566C (no) 1989-08-30
NZ197965A (en) 1984-03-16
FI74020B (fi) 1987-08-31
SE452324B (sv) 1987-11-23
IE811811L (en) 1982-02-11

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Legal Events

Date Code Title Description
ST Notification of lapse