FR2473524A1 - Derives n-glycosyliques des antibiotiques du groupe des anthracyclines et procede pour leur obtention - Google Patents

Derives n-glycosyliques des antibiotiques du groupe des anthracyclines et procede pour leur obtention Download PDF

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Publication number
FR2473524A1
FR2473524A1 FR8019344A FR8019344A FR2473524A1 FR 2473524 A1 FR2473524 A1 FR 2473524A1 FR 8019344 A FR8019344 A FR 8019344A FR 8019344 A FR8019344 A FR 8019344A FR 2473524 A1 FR2473524 A1 FR 2473524A1
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FR
France
Prior art keywords
derivatives
antibiotic
group
denotes
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8019344A
Other languages
English (en)
French (fr)
Other versions
FR2473524B1 (enExample
Inventor
Barbara Stefanska
Leonard Falkowski
Edward Borowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gdansk University of Technology
Original Assignee
Gdansk University of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gdansk University of Technology filed Critical Gdansk University of Technology
Publication of FR2473524A1 publication Critical patent/FR2473524A1/fr
Application granted granted Critical
Publication of FR2473524B1 publication Critical patent/FR2473524B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8019344A 1979-10-17 1980-09-08 Derives n-glycosyliques des antibiotiques du groupe des anthracyclines et procede pour leur obtention Granted FR2473524A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL1979219049A PL124284B1 (en) 1979-10-17 1979-10-17 Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group

Publications (2)

Publication Number Publication Date
FR2473524A1 true FR2473524A1 (fr) 1981-07-17
FR2473524B1 FR2473524B1 (enExample) 1983-06-03

Family

ID=19998972

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8019344A Granted FR2473524A1 (fr) 1979-10-17 1980-09-08 Derives n-glycosyliques des antibiotiques du groupe des anthracyclines et procede pour leur obtention

Country Status (11)

Country Link
US (1) US4351937A (enExample)
JP (1) JPS5914479B2 (enExample)
BE (1) BE884318A (enExample)
DE (1) DE3028148C2 (enExample)
DK (1) DK305880A (enExample)
FI (1) FI67708C (enExample)
FR (1) FR2473524A1 (enExample)
GB (1) GB2060609B (enExample)
PL (1) PL124284B1 (enExample)
SE (1) SE8005099L (enExample)
SU (2) SU1011051A3 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648327A5 (de) * 1980-10-16 1985-03-15 Hoffmann La Roche Anthracycline.
JPS6297A (ja) * 1985-06-24 1987-01-06 Microbial Chem Res Found アントラサイクリン化合物
US4863739A (en) * 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
WO1989006654A1 (en) * 1988-01-19 1989-07-27 Board Of Regents, The University Of Texas System Glycosides, liposomal compositions thereof, and methods for their use
EP0648503B1 (en) * 1993-09-22 2000-07-26 Hoechst Aktiengesellschaft Pro-prodrugs, their production and use
GB9727546D0 (en) * 1997-12-31 1998-03-18 Pharmacia & Upjohn Spa Anthracycline glycosides
WO2000056267A2 (en) * 1999-03-19 2000-09-28 Waldemar Priebe Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics
EP1278527A4 (en) 2000-01-14 2003-04-09 Intrabiotics Pharmaceuticals DERIVATIVES OF POLYEN MACROLIDES, THEIR PRODUCTION AND USE
CN104211738B (zh) * 2014-08-15 2016-09-28 合肥合源药业有限公司 一种伊达比星中的杂质、其制备方法及其应用
RU2642068C1 (ru) * 2017-04-26 2018-01-24 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60877C (fi) * 1971-08-13 1982-04-13 Politechnika Gdanska Foerfarande foer framstaellning av terapeutiskt aktiva i vatten laett dispergerbara polyenmakrolidantibiot-n-glykosylderivat
JPS5323961A (en) * 1976-08-16 1978-03-06 Microbial Chem Res Found Antitumors
GB1561507A (en) * 1976-11-17 1980-02-20 Farmaceutici Italia Snthracycline disaccharides
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/77 *

Also Published As

Publication number Publication date
FR2473524B1 (enExample) 1983-06-03
GB2060609A (en) 1981-05-07
JPS5914479B2 (ja) 1984-04-04
JPS5663994A (en) 1981-05-30
FI67708B (fi) 1985-01-31
SU1011051A3 (ru) 1983-04-07
SE8005099L (sv) 1981-04-18
DK305880A (da) 1981-04-18
PL219049A1 (enExample) 1981-05-08
SU1054352A1 (ru) 1983-11-15
PL124284B1 (en) 1983-01-31
DE3028148A1 (de) 1981-04-30
BE884318A (fr) 1980-11-03
US4351937A (en) 1982-09-28
DE3028148C2 (de) 1984-10-25
FI802332A7 (fi) 1981-04-18
FI67708C (fi) 1985-05-10
GB2060609B (en) 1984-09-05

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