FR2455043A1 - Cristallisation du sel sesqui-sodique d'un diacide d'oxa-b-lactame antibiotique - Google Patents

Cristallisation du sel sesqui-sodique d'un diacide d'oxa-b-lactame antibiotique

Info

Publication number
FR2455043A1
FR2455043A1 FR8008779A FR8008779A FR2455043A1 FR 2455043 A1 FR2455043 A1 FR 2455043A1 FR 8008779 A FR8008779 A FR 8008779A FR 8008779 A FR8008779 A FR 8008779A FR 2455043 A1 FR2455043 A1 FR 2455043A1
Authority
FR
France
Prior art keywords
diacide
sesqui
oxa
lactam
sodium salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8008779A
Other languages
English (en)
Other versions
FR2455043B1 (fr
Inventor
William Joe Wheeler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2455043A1 publication Critical patent/FR2455043A1/fr
Application granted granted Critical
Publication of FR2455043B1 publication Critical patent/FR2455043B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SEL D-SESQUI-SODIQUE DU DERIVE DE DIACIDE D'OXA-B-LACTAME DE FORMULE: (CF DESSIN DANS BOPI) ESSENTIELLEMENT EXEMPT DE LA FORME L. CETTE FORME CRISTALLISEE CONVIENT PARTICULIEREMENT BIEN A L'UTILISATION THERAPEUTIQUE DU COMPOSE EN TANT QU'AGENT ANTIBIOTIQUE.
FR8008779A 1979-04-24 1980-04-18 Cristallisation du sel sesqui-sodique d'un diacide d'oxa-b-lactame antibiotique Granted FR2455043A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/032,840 US4259485A (en) 1979-04-24 1979-04-24 Crystallization process

Publications (2)

Publication Number Publication Date
FR2455043A1 true FR2455043A1 (fr) 1980-11-21
FR2455043B1 FR2455043B1 (fr) 1983-08-05

Family

ID=21867102

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8008779A Granted FR2455043A1 (fr) 1979-04-24 1980-04-18 Cristallisation du sel sesqui-sodique d'un diacide d'oxa-b-lactame antibiotique

Country Status (34)

Country Link
US (1) US4259485A (fr)
EP (1) EP0018760B1 (fr)
JP (1) JPS55143992A (fr)
KR (1) KR840000036B1 (fr)
AR (1) AR225174A1 (fr)
AT (1) AT368158B (fr)
AU (1) AU531272B2 (fr)
BE (1) BE882849A (fr)
BG (1) BG34904A3 (fr)
CA (1) CA1124236A (fr)
CH (1) CH645901A5 (fr)
CS (1) CS212347B2 (fr)
DD (1) DD150205A5 (fr)
DE (1) DE3067412D1 (fr)
DK (1) DK172880A (fr)
EG (1) EG14334A (fr)
ES (1) ES8200110A1 (fr)
FI (1) FI801252A (fr)
FR (1) FR2455043A1 (fr)
GB (1) GB2047703B (fr)
GR (1) GR68048B (fr)
HU (1) HU182127B (fr)
IE (1) IE49703B1 (fr)
IL (1) IL59895A (fr)
IT (1) IT1141294B (fr)
LU (1) LU82384A1 (fr)
NZ (1) NZ193482A (fr)
PH (1) PH15146A (fr)
PL (1) PL124423B1 (fr)
PT (1) PT71115A (fr)
RO (1) RO79315A (fr)
SU (1) SU925251A3 (fr)
YU (1) YU108180A (fr)
ZA (1) ZA802329B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2484835A1 (fr) * 1980-06-23 1981-12-24 Shionogi & Co Preparations stables de b-lactames antibacteriens lyophilises renfermant un compose de sucre ou d'alcool sucre comme agent de stabilisation

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56103185A (en) * 1980-01-22 1981-08-18 Shionogi & Co Ltd Malonamidoxa-dethia-cephem compound
JPS597193A (ja) * 1982-07-02 1984-01-14 Shionogi & Co Ltd マロニルメチル基の異性化方法
RU2555360C2 (ru) * 2012-11-06 2015-07-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ определения воды в координационных соединениях

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2345452A1 (fr) * 1976-03-25 1977-10-21 Shionogi & Co Procede de preparation d'arylmalonamido-1-oxadethiacephalosporines et nouveaux produits ainsi obtenus, a activite antibacterienne

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1557552A (en) * 1977-02-15 1979-12-12 Shionogi & Co 1 oxadethiacepham compounds
CA1100962A (fr) * 1977-04-28 1981-05-12 Yoshio Hamashima Haloarylmalonamidooxacephalosporines
JPS609718B2 (ja) * 1977-08-25 1985-03-12 塩野義製薬株式会社 チアジアゾリルチオセフアロスポリン類縁抗生物質
BE871213R (fr) * 1978-10-12 1979-02-01 Shionogi & Co Arylmalonamido-1-oxadethiacephalosporines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2345452A1 (fr) * 1976-03-25 1977-10-21 Shionogi & Co Procede de preparation d'arylmalonamido-1-oxadethiacephalosporines et nouveaux produits ainsi obtenus, a activite antibacterienne
US4138486A (en) * 1976-03-25 1979-02-06 Shionogi & Co., Ltd. Arylmalonamido-1-oxadethiacephalosporins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/79 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2484835A1 (fr) * 1980-06-23 1981-12-24 Shionogi & Co Preparations stables de b-lactames antibacteriens lyophilises renfermant un compose de sucre ou d'alcool sucre comme agent de stabilisation

Also Published As

Publication number Publication date
DE3067412D1 (en) 1984-05-17
SU925251A3 (ru) 1982-04-30
IT8021527A0 (it) 1980-04-21
FR2455043B1 (fr) 1983-08-05
AU531272B2 (en) 1983-08-18
CA1124236A (fr) 1982-05-25
KR840000036B1 (ko) 1984-01-28
IT1141294B (it) 1986-10-01
LU82384A1 (fr) 1980-07-31
RO79315A (fr) 1982-08-17
GR68048B (fr) 1981-10-29
ATA207380A (de) 1982-01-15
ES490828A0 (es) 1981-10-16
BG34904A3 (en) 1983-12-15
GB2047703B (en) 1983-04-20
AT368158B (de) 1982-09-27
ES8200110A1 (es) 1981-10-16
EP0018760B1 (fr) 1984-04-11
GB2047703A (en) 1980-12-03
IE49703B1 (en) 1985-11-27
JPS6242915B2 (fr) 1987-09-10
JPS55143992A (en) 1980-11-10
US4259485A (en) 1981-03-31
ZA802329B (en) 1981-11-25
EG14334A (en) 1983-12-31
CH645901A5 (fr) 1984-10-31
PL223649A1 (fr) 1981-02-13
HU182127B (en) 1983-12-28
AU5763380A (en) 1980-10-30
BE882849A (fr) 1980-10-20
FI801252A (fi) 1980-10-25
PL124423B1 (en) 1983-01-31
YU108180A (en) 1983-02-28
PT71115A (en) 1980-05-01
DD150205A5 (de) 1981-08-19
EP0018760A1 (fr) 1980-11-12
NZ193482A (en) 1982-03-23
IE800804L (en) 1980-10-24
CS212347B2 (en) 1982-03-26
IL59895A (en) 1983-05-15
DK172880A (da) 1980-10-25
AR225174A1 (es) 1982-02-26
KR830002778A (ko) 1983-05-30
PH15146A (en) 1982-08-24

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Legal Events

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