FR2413403A1 - Nouveaux derives 4''-deoxy-4''-acylamido de l'oleandomycine, de l'erythromycine et du carbonate d'erythromycine, leur procede de production et composition pharmaceutique les contenant - Google Patents
Nouveaux derives 4''-deoxy-4''-acylamido de l'oleandomycine, de l'erythromycine et du carbonate d'erythromycine, leur procede de production et composition pharmaceutique les contenantInfo
- Publication number
- FR2413403A1 FR2413403A1 FR7900014A FR7900014A FR2413403A1 FR 2413403 A1 FR2413403 A1 FR 2413403A1 FR 7900014 A FR7900014 A FR 7900014A FR 7900014 A FR7900014 A FR 7900014A FR 2413403 A1 FR2413403 A1 FR 2413403A1
- Authority
- FR
- France
- Prior art keywords
- erythromycin
- oleandomycin
- deoxy
- new
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 3
- ZWCGOSCDWAAFKK-YZPBMOCRSA-N carbonic acid;(3r,4s,5s,6r,7r,9r,11r,12r,13s,14r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2, Chemical compound OC(O)=O.O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ZWCGOSCDWAAFKK-YZPBMOCRSA-N 0.000 title abstract 2
- RZPAKFUAFGMUPI-KGIGTXTPSA-N oleandomycin Chemical class O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@@H](C)C(=O)[C@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C RZPAKFUAFGMUPI-KGIGTXTPSA-N 0.000 title abstract 2
- 229960003276 erythromycin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- XCLJRCAJSCMIND-JCTYMORFSA-N (9S)-erythromycyclamine Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)[C@@H](N)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 XCLJRCAJSCMIND-JCTYMORFSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86672278A | 1978-01-03 | 1978-01-03 | |
| US05/937,640 US4180654A (en) | 1978-01-03 | 1978-08-29 | 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2413403A1 true FR2413403A1 (fr) | 1979-07-27 |
| FR2413403B1 FR2413403B1 (en, 2012) | 1982-07-23 |
Family
ID=27127966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7900014A Granted FR2413403A1 (fr) | 1978-01-03 | 1979-01-02 | Nouveaux derives 4''-deoxy-4''-acylamido de l'oleandomycine, de l'erythromycine et du carbonate d'erythromycine, leur procede de production et composition pharmaceutique les contenant |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4180654A (en, 2012) |
| JP (1) | JPS5495585A (en, 2012) |
| AT (1) | AT364457B (en, 2012) |
| AU (1) | AU506684B2 (en, 2012) |
| CH (1) | CH639972A5 (en, 2012) |
| CS (1) | CS204042B2 (en, 2012) |
| DD (1) | DD141026A5 (en, 2012) |
| DE (2) | DE2953969C2 (en, 2012) |
| DK (1) | DK147943C (en, 2012) |
| ES (2) | ES476544A1 (en, 2012) |
| FI (1) | FI68058C (en, 2012) |
| FR (1) | FR2413403A1 (en, 2012) |
| GB (1) | GB2013181B (en, 2012) |
| GR (1) | GR72779B (en, 2012) |
| HU (1) | HU180276B (en, 2012) |
| IE (1) | IE47642B1 (en, 2012) |
| IL (1) | IL56363A (en, 2012) |
| IN (1) | IN150395B (en, 2012) |
| IT (1) | IT1109925B (en, 2012) |
| LU (1) | LU80747A1 (en, 2012) |
| NL (1) | NL176461C (en, 2012) |
| NO (2) | NO146711C (en, 2012) |
| NZ (1) | NZ189274A (en, 2012) |
| PH (4) | PH14745A (en, 2012) |
| PL (2) | PL117603B1 (en, 2012) |
| PT (1) | PT69014A (en, 2012) |
| SE (2) | SE447118B (en, 2012) |
| YU (2) | YU312278A (en, 2012) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0114486A3 (en) * | 1982-12-27 | 1984-12-12 | Pfizer Inc. | Alkylation of oleandomycin |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5848285U (ja) * | 1981-09-26 | 1983-04-01 | コナミ工業株式会社 | テ−ブル型テレビゲ−ム機 |
| US4518590A (en) * | 1984-04-13 | 1985-05-21 | Pfizer Inc. | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method |
| JPS62240086A (ja) * | 1986-04-12 | 1987-10-20 | 株式会社 エ−ス電研 | 遊技機の前面構造 |
| US5075289A (en) * | 1988-06-07 | 1991-12-24 | Abbott Laboratories | 9-r-azacyclic erythromycin antibiotics |
| YU55690A (en) * | 1990-03-21 | 1990-12-31 | Pliva Pharm & Chem Works | Process for preparing oleandomycin oxime |
| GB0310980D0 (en) * | 2003-05-13 | 2003-06-18 | Glaxo Group Ltd | Novel compounds |
| WO2004101587A1 (en) * | 2003-05-13 | 2004-11-25 | Glaxo Group Limited | Novel 14 and 15 memberred-ring compounds |
| GB0310992D0 (en) * | 2003-05-13 | 2003-06-18 | Glaxo Group Ltd | Novel compounds |
| GB0310984D0 (en) * | 2003-05-13 | 2003-06-18 | Glaxo Group Ltd | Novel compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3869445A (en) * | 1973-05-03 | 1975-03-04 | Abbott Lab | 4{41 -O-sulfonyl erythromycin-9-O-oxime derivatives |
| US3884902A (en) * | 1973-05-04 | 1975-05-20 | Abbott Lab | Sulfonyl derivatives of erythromycin |
| US3884903A (en) * | 1973-06-21 | 1975-05-20 | Abbott Lab | 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives |
| US4063014A (en) * | 1975-06-12 | 1977-12-13 | Abbott Laboratories | 4"-O-sulfonyl erythromycin-9-O-oxime derivatives |
| US4069379A (en) * | 1976-07-08 | 1978-01-17 | Pfizer Inc. | Semi-synthetic oleandomycins |
| IE44509B1 (en) * | 1976-03-03 | 1981-12-30 | Pfizer | Semi-synthetic oleandomycins |
| US4085119A (en) * | 1977-02-04 | 1978-04-18 | Pfizer Inc. | 4-Substituted amino derivatives of oleandomycin |
| US4090017A (en) * | 1977-02-04 | 1978-05-16 | Pfizer Inc. | 4-Deoxy-4-substituted amino derivatives of oleandomycin |
-
1978
- 1978-08-29 US US05/937,640 patent/US4180654A/en not_active Expired - Lifetime
- 1978-11-15 DK DK507778A patent/DK147943C/da not_active IP Right Cessation
- 1978-11-20 IN IN830/DEL/78A patent/IN150395B/en unknown
- 1978-12-20 GB GB7849227A patent/GB2013181B/en not_active Expired
- 1978-12-21 CH CH1303678A patent/CH639972A5/de not_active IP Right Cessation
- 1978-12-21 NZ NZ189274A patent/NZ189274A/xx unknown
- 1978-12-28 JP JP16447078A patent/JPS5495585A/ja active Granted
- 1978-12-28 YU YU03122/78A patent/YU312278A/xx unknown
- 1978-12-29 HU HU78PI660A patent/HU180276B/hu not_active IP Right Cessation
- 1978-12-29 AU AU42985/78A patent/AU506684B2/en not_active Expired
- 1978-12-30 GR GR58008A patent/GR72779B/el unknown
-
1979
- 1979-01-02 FI FI790004A patent/FI68058C/fi not_active IP Right Cessation
- 1979-01-02 PH PH22004A patent/PH14745A/en unknown
- 1979-01-02 LU LU80747A patent/LU80747A1/xx unknown
- 1979-01-02 PT PT69014A patent/PT69014A/pt unknown
- 1979-01-02 IT IT19013/79A patent/IT1109925B/it active
- 1979-01-02 IE IE5/79A patent/IE47642B1/en not_active IP Right Cessation
- 1979-01-02 ES ES476544A patent/ES476544A1/es not_active Expired
- 1979-01-02 FR FR7900014A patent/FR2413403A1/fr active Granted
- 1979-01-02 IL IL56363A patent/IL56363A/xx not_active IP Right Cessation
- 1979-01-02 AT AT0002979A patent/AT364457B/de not_active IP Right Cessation
- 1979-01-02 NO NO790006A patent/NO146711C/no unknown
- 1979-01-02 SE SE7900028A patent/SE447118B/sv not_active IP Right Cessation
- 1979-01-02 NL NLAANVRAGE7900006,A patent/NL176461C/xx not_active IP Right Cessation
- 1979-01-03 DE DE2953969A patent/DE2953969C2/de not_active Expired
- 1979-01-03 DE DE19792900118 patent/DE2900118A1/de active Granted
- 1979-01-03 CS CS79100A patent/CS204042B2/cs unknown
- 1979-01-03 PL PL1979212593A patent/PL117603B1/pl unknown
- 1979-01-03 PL PL1979227812A patent/PL118573B1/pl unknown
- 1979-01-03 DD DD79210317A patent/DD141026A5/de unknown
- 1979-07-11 ES ES482420A patent/ES482420A1/es not_active Expired
- 1979-12-21 PH PH23449A patent/PH15439A/en unknown
- 1979-12-21 PH PH23451A patent/PH15752A/en unknown
- 1979-12-21 PH PH23450A patent/PH15626A/en unknown
-
1982
- 1982-02-26 NO NO820613A patent/NO147716C/no unknown
- 1982-09-24 YU YU02139/82A patent/YU213982A/xx unknown
-
1983
- 1983-08-15 SE SE8304417A patent/SE448385B/sv not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0114486A3 (en) * | 1982-12-27 | 1984-12-12 | Pfizer Inc. | Alkylation of oleandomycin |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |