FR2389628A2 - - Google Patents
Info
- Publication number
- FR2389628A2 FR2389628A2 FR7725388A FR7725388A FR2389628A2 FR 2389628 A2 FR2389628 A2 FR 2389628A2 FR 7725388 A FR7725388 A FR 7725388A FR 7725388 A FR7725388 A FR 7725388A FR 2389628 A2 FR2389628 A2 FR 2389628A2
- Authority
- FR
- France
- Prior art keywords
- aminolysis
- methylene
- hydrogenation
- sleep
- dioxatricyclodecanes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
a. Procédé de fabrication de 2,9-dioxatricycloØ4,3,1,0**3,**7õ décanes comprenant un reste d'amine tertiaire en position 3' à partir de 3-iodométhyl - 4 beta - acétoxy-10-méthylène - 2,9- dioxatricyclodécanes par aminolyse et hydrogénation, suivant ce qui est indiqué au brevet principal. b. Pour obtenir un produit plus pur, on procède d'abord à l'hydrogénation catalytique de la double liaison raccordant le methylene, on isole les composés 10-méthylés épimères du mélange de réaction puis on les soumet à une aminolyse et éventuellement, encore, à d'autres réactions postérieures. c. Les produits obtenus sont caractérisés par des effets spécifiques sur le sommeil profond et sur le sommeil paradoxal.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2719916A DE2719916C2 (de) | 1977-05-04 | 1977-05-04 | Verfahren zur Herstellung von 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decanen |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2389628A2 true FR2389628A2 (fr) | 1978-12-01 |
FR2389628B2 FR2389628B2 (fr) | 1981-01-23 |
Family
ID=6007994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7725388A Expired FR2389628B2 (fr) | 1977-05-04 | 1977-08-19 |
Country Status (23)
Country | Link |
---|---|
US (1) | US4182889A (fr) |
JP (2) | JPS53137995A (fr) |
AT (1) | AT352139B (fr) |
AU (1) | AU512406B2 (fr) |
BE (1) | BE857981R (fr) |
CA (1) | CA1130300A (fr) |
CH (1) | CH638213A5 (fr) |
DD (1) | DD132871A6 (fr) |
DE (1) | DE2719916C2 (fr) |
DK (1) | DK273977A (fr) |
ES (1) | ES461131A2 (fr) |
FI (1) | FI772488A (fr) |
FR (1) | FR2389628B2 (fr) |
GB (1) | GB1581263A (fr) |
GR (1) | GR70658B (fr) |
IE (1) | IE45756B1 (fr) |
MX (1) | MX4851E (fr) |
NL (1) | NL7706640A (fr) |
NO (1) | NO146360C (fr) |
PH (1) | PH15677A (fr) |
SE (1) | SE439310B (fr) |
SU (1) | SU724084A3 (fr) |
ZA (1) | ZA774753B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0136662A2 (fr) * | 1983-10-01 | 1985-04-10 | Kali-Chemie Pharma GmbH | 2,6-Dioxa-bicyclo-[2,2,2]-octan-7-yl-acetaldéhydes |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2547205C2 (de) * | 1975-10-22 | 1983-12-08 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung |
DE3335826A1 (de) * | 1983-10-01 | 1985-04-18 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Neue n-(2,10-dioxa-tricyclo-(5,3,1,0(pfeil hoch)3(pfeil hoch)(pfeil hoch),(pfeil hoch)(pfeil hoch)8(pfeil hoch))- undecan-5-yl)-tryptamin-derivate |
SE510643C2 (sv) * | 1997-06-27 | 1999-06-14 | Astra Ab | Termodynamiskt stabil omeprazol natrium form B |
DE10130145A1 (de) * | 2001-06-22 | 2003-01-02 | Wella Ag | Kationische Farbstoffe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Färbemittel |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3812154A (en) * | 1969-12-08 | 1974-05-21 | Kali Chemie Ag | Dioxatricyclodecanes |
DE2129507C3 (de) | 1971-06-15 | 1980-02-14 | Kali-Chemie Ag, 3000 Hannover | Verfahren zur Herstellung von 8-Alkoxy-3halogenmethyl-4-acetoxy- 10-methylen-2,9dioxatricyclo(43,l,03 7 )decanen |
FI56533C (fi) | 1973-02-08 | 1980-02-11 | Kali Chemie Pharma Gmbh | Saett att framstaella nya 4alfa-karbamyloxi-8-alkoxi-10-metylen-3-metyl-2,9-dioxatricyklo(4,3,1,03,7)-dekaner |
-
1977
- 1977-05-04 DE DE2719916A patent/DE2719916C2/de not_active Expired
- 1977-05-24 NO NO771806A patent/NO146360C/no unknown
- 1977-05-28 GR GR53578A patent/GR70658B/el unknown
- 1977-06-16 NL NL7706640A patent/NL7706640A/xx not_active Application Discontinuation
- 1977-06-21 DK DK273977A patent/DK273977A/da not_active Application Discontinuation
- 1977-07-11 IE IE1428/77A patent/IE45756B1/en unknown
- 1977-07-11 GB GB29095/77A patent/GB1581263A/en not_active Expired
- 1977-07-21 MX MX77100803U patent/MX4851E/es unknown
- 1977-07-28 AT AT554377A patent/AT352139B/de not_active IP Right Cessation
- 1977-07-29 ES ES461131A patent/ES461131A2/es not_active Expired
- 1977-08-05 ZA ZA00774753A patent/ZA774753B/xx unknown
- 1977-08-08 CH CH971477A patent/CH638213A5/de not_active IP Right Cessation
- 1977-08-09 CA CA284,645A patent/CA1130300A/fr not_active Expired
- 1977-08-10 AU AU27794/77A patent/AU512406B2/en not_active Expired
- 1977-08-15 JP JP9771777A patent/JPS53137995A/ja active Pending
- 1977-08-18 SE SE7709317A patent/SE439310B/xx not_active IP Right Cessation
- 1977-08-18 DD DD7700200649A patent/DD132871A6/xx not_active IP Right Cessation
- 1977-08-19 SU SU772511707A patent/SU724084A3/ru active
- 1977-08-19 BE BE6046120A patent/BE857981R/fr not_active IP Right Cessation
- 1977-08-19 FI FI772488A patent/FI772488A/fi not_active Application Discontinuation
- 1977-08-19 FR FR7725388A patent/FR2389628B2/fr not_active Expired
- 1977-08-22 PH PH20155A patent/PH15677A/en unknown
- 1977-08-22 US US05/826,636 patent/US4182889A/en not_active Expired - Lifetime
-
1985
- 1985-11-06 JP JP60247310A patent/JPS61197584A/ja active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0136662A2 (fr) * | 1983-10-01 | 1985-04-10 | Kali-Chemie Pharma GmbH | 2,6-Dioxa-bicyclo-[2,2,2]-octan-7-yl-acetaldéhydes |
EP0136662A3 (en) * | 1983-10-01 | 1986-02-12 | Kali-Chemie Pharma Gmbh | 2,6-dioxa-bicyclo-û2,2,2¨-octan-7-yl-acetaldehydes |
Also Published As
Publication number | Publication date |
---|---|
IE45756B1 (en) | 1982-11-17 |
SU724084A3 (ru) | 1980-03-25 |
SE7709317L (sv) | 1978-11-05 |
DE2719916A1 (de) | 1978-11-09 |
FR2389628B2 (fr) | 1981-01-23 |
JPS61197584A (ja) | 1986-09-01 |
NO146360C (no) | 1982-09-15 |
SE439310B (sv) | 1985-06-10 |
FI772488A (fi) | 1978-11-05 |
DD132871A6 (de) | 1978-11-15 |
DE2719916C2 (de) | 1987-03-19 |
GR70658B (fr) | 1982-12-03 |
MX4851E (es) | 1982-11-01 |
NL7706640A (nl) | 1978-11-07 |
BE857981R (fr) | 1978-02-20 |
CA1130300A (fr) | 1982-08-24 |
JPS6160078B2 (fr) | 1986-12-19 |
CH638213A5 (de) | 1983-09-15 |
DK273977A (da) | 1978-11-05 |
ES461131A2 (es) | 1978-06-01 |
NO771806L (no) | 1978-11-07 |
US4182889A (en) | 1980-01-08 |
GB1581263A (en) | 1980-12-10 |
AT352139B (de) | 1979-09-10 |
PH15677A (en) | 1983-03-11 |
NO146360B (no) | 1982-06-07 |
AU512406B2 (en) | 1980-10-09 |
AU2779477A (en) | 1979-02-15 |
ZA774753B (en) | 1978-06-28 |
ATA554377A (de) | 1979-02-15 |
JPS53137995A (en) | 1978-12-01 |
IE45756L (en) | 1978-11-04 |
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