FR2389628A2 - - Google Patents

Info

Publication number
FR2389628A2
FR2389628A2 FR7725388A FR7725388A FR2389628A2 FR 2389628 A2 FR2389628 A2 FR 2389628A2 FR 7725388 A FR7725388 A FR 7725388A FR 7725388 A FR7725388 A FR 7725388A FR 2389628 A2 FR2389628 A2 FR 2389628A2
Authority
FR
France
Prior art keywords
aminolysis
methylene
hydrogenation
sleep
dioxatricyclodecanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7725388A
Other languages
English (en)
Other versions
FR2389628B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Publication of FR2389628A2 publication Critical patent/FR2389628A2/fr
Application granted granted Critical
Publication of FR2389628B2 publication Critical patent/FR2389628B2/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

a. Procédé de fabrication de 2,9-dioxatricycloØ4,3,1,0**3,**7õ décanes comprenant un reste d'amine tertiaire en position 3' à partir de 3-iodométhyl - 4 beta - acétoxy-10-méthylène - 2,9- dioxatricyclodécanes par aminolyse et hydrogénation, suivant ce qui est indiqué au brevet principal. b. Pour obtenir un produit plus pur, on procède d'abord à l'hydrogénation catalytique de la double liaison raccordant le methylene, on isole les composés 10-méthylés épimères du mélange de réaction puis on les soumet à une aminolyse et éventuellement, encore, à d'autres réactions postérieures. c. Les produits obtenus sont caractérisés par des effets spécifiques sur le sommeil profond et sur le sommeil paradoxal.
FR7725388A 1977-05-04 1977-08-19 Expired FR2389628B2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2719916A DE2719916C2 (de) 1977-05-04 1977-05-04 Verfahren zur Herstellung von 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decanen

Publications (2)

Publication Number Publication Date
FR2389628A2 true FR2389628A2 (fr) 1978-12-01
FR2389628B2 FR2389628B2 (fr) 1981-01-23

Family

ID=6007994

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7725388A Expired FR2389628B2 (fr) 1977-05-04 1977-08-19

Country Status (23)

Country Link
US (1) US4182889A (fr)
JP (2) JPS53137995A (fr)
AT (1) AT352139B (fr)
AU (1) AU512406B2 (fr)
BE (1) BE857981R (fr)
CA (1) CA1130300A (fr)
CH (1) CH638213A5 (fr)
DD (1) DD132871A6 (fr)
DE (1) DE2719916C2 (fr)
DK (1) DK273977A (fr)
ES (1) ES461131A2 (fr)
FI (1) FI772488A (fr)
FR (1) FR2389628B2 (fr)
GB (1) GB1581263A (fr)
GR (1) GR70658B (fr)
IE (1) IE45756B1 (fr)
MX (1) MX4851E (fr)
NL (1) NL7706640A (fr)
NO (1) NO146360C (fr)
PH (1) PH15677A (fr)
SE (1) SE439310B (fr)
SU (1) SU724084A3 (fr)
ZA (1) ZA774753B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0136662A2 (fr) * 1983-10-01 1985-04-10 Kali-Chemie Pharma GmbH 2,6-Dioxa-bicyclo-[2,2,2]-octan-7-yl-acetaldéhydes

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2547205C2 (de) * 1975-10-22 1983-12-08 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
DE3335826A1 (de) * 1983-10-01 1985-04-18 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue n-(2,10-dioxa-tricyclo-(5,3,1,0(pfeil hoch)3(pfeil hoch)(pfeil hoch),(pfeil hoch)(pfeil hoch)8(pfeil hoch))- undecan-5-yl)-tryptamin-derivate
SE510643C2 (sv) * 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
DE10130145A1 (de) * 2001-06-22 2003-01-02 Wella Ag Kationische Farbstoffe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Färbemittel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3812154A (en) * 1969-12-08 1974-05-21 Kali Chemie Ag Dioxatricyclodecanes
DE2129507C3 (de) 1971-06-15 1980-02-14 Kali-Chemie Ag, 3000 Hannover Verfahren zur Herstellung von 8-Alkoxy-3halogenmethyl-4-acetoxy- 10-methylen-2,9dioxatricyclo(43,l,03 7 )decanen
FI56533C (fi) 1973-02-08 1980-02-11 Kali Chemie Pharma Gmbh Saett att framstaella nya 4alfa-karbamyloxi-8-alkoxi-10-metylen-3-metyl-2,9-dioxatricyklo(4,3,1,03,7)-dekaner

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0136662A2 (fr) * 1983-10-01 1985-04-10 Kali-Chemie Pharma GmbH 2,6-Dioxa-bicyclo-[2,2,2]-octan-7-yl-acetaldéhydes
EP0136662A3 (en) * 1983-10-01 1986-02-12 Kali-Chemie Pharma Gmbh 2,6-dioxa-bicyclo-û2,2,2¨-octan-7-yl-acetaldehydes

Also Published As

Publication number Publication date
IE45756B1 (en) 1982-11-17
SU724084A3 (ru) 1980-03-25
SE7709317L (sv) 1978-11-05
DE2719916A1 (de) 1978-11-09
FR2389628B2 (fr) 1981-01-23
JPS61197584A (ja) 1986-09-01
NO146360C (no) 1982-09-15
SE439310B (sv) 1985-06-10
FI772488A (fi) 1978-11-05
DD132871A6 (de) 1978-11-15
DE2719916C2 (de) 1987-03-19
GR70658B (fr) 1982-12-03
MX4851E (es) 1982-11-01
NL7706640A (nl) 1978-11-07
BE857981R (fr) 1978-02-20
CA1130300A (fr) 1982-08-24
JPS6160078B2 (fr) 1986-12-19
CH638213A5 (de) 1983-09-15
DK273977A (da) 1978-11-05
ES461131A2 (es) 1978-06-01
NO771806L (no) 1978-11-07
US4182889A (en) 1980-01-08
GB1581263A (en) 1980-12-10
AT352139B (de) 1979-09-10
PH15677A (en) 1983-03-11
NO146360B (no) 1982-06-07
AU512406B2 (en) 1980-10-09
AU2779477A (en) 1979-02-15
ZA774753B (en) 1978-06-28
ATA554377A (de) 1979-02-15
JPS53137995A (en) 1978-12-01
IE45756L (en) 1978-11-04

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