FR2455586A1 - Nouveaux carbonates organiques, leur procede de fabrication et leurs utilisations pour la formation d'esters actifs d'acides amines - Google Patents

Nouveaux carbonates organiques, leur procede de fabrication et leurs utilisations pour la formation d'esters actifs d'acides amines

Info

Publication number
FR2455586A1
FR2455586A1 FR8010130A FR8010130A FR2455586A1 FR 2455586 A1 FR2455586 A1 FR 2455586A1 FR 8010130 A FR8010130 A FR 8010130A FR 8010130 A FR8010130 A FR 8010130A FR 2455586 A1 FR2455586 A1 FR 2455586A1
Authority
FR
France
Prior art keywords
amino
formation
acid esters
amino acid
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8010130A
Other languages
English (en)
Other versions
FR2455586B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2455586A1 publication Critical patent/FR2455586A1/fr
Application granted granted Critical
Publication of FR2455586B1 publication Critical patent/FR2455586B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/72—4,7-Endo-alkylene-iso-indoles
    • C07D209/76—4,7-Endo-alkylene-iso-indoles with oxygen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

CES NOUVEAUX CARBONATES PRESENTENT LA FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN GROUPE SUCCINIMIDO, PHTALIMIDO OU 5-NORBORNENE-2,3-DICARBOXIMIDO. ILS SONT PREPARES PAR REACTION D'UN COMPOSE N-HYDROXY DE FORMULE ROH, DANS LAQUELLE R A LES DEFINITIONS CI-DESSUS AVEC UN AGENT DE SILYLATION, SUIVIE D'UNE REACTION DU PRODUIT SILYLE OBTENU AVEC LE PHOSGENE OU AVEC LE TRICHLOROMETHYLCHLOROFORMIATE, SOIT A L'ETAT FONDU, SOIT EN PRESENCE D'UN SOLVANT ORGANIQUE NON POLAIRE. CES COMPOSES SONT UTILES NON SEULEMENT COMME REACTIFS DE FORMATION D'ESTERS ACTIFS D'ACIDES AMINES MAIS AUSSI COMME REACTIFS PERMETTANT D'INTRODUIRE UN GROUPE CARBONYLE ENTRE DEUX GROUPES AMINO, DES GROUPES AMINO ET HYDROXYLE OU DES GROUPES AMINO ET MERCAPTO, DE FORMER UN ISOTHIOCYANATE A PARTIR D'UN ACIDE DITHIOCARBAMIDE PAR ELIMINATION D'HYDROGENE SULFURE DE CE DERNIER, AINSI QUE DE FORMER DES DERIVES D'ACIDE ACRYLIQUE A PARTIR DE SERINE N-PROTEGEE PAR DESHYDRATATION DE CELLE-CI.
FR8010130A 1979-05-02 1980-04-30 Nouveaux carbonates organiques, leur procede de fabrication et leurs utilisations pour la formation d'esters actifs d'acides amines Granted FR2455586A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5334779A JPS55145665A (en) 1979-05-02 1979-05-02 Agent for forming active ester of amino acid

Publications (2)

Publication Number Publication Date
FR2455586A1 true FR2455586A1 (fr) 1980-11-28
FR2455586B1 FR2455586B1 (fr) 1983-03-11

Family

ID=12940233

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8010130A Granted FR2455586A1 (fr) 1979-05-02 1980-04-30 Nouveaux carbonates organiques, leur procede de fabrication et leurs utilisations pour la formation d'esters actifs d'acides amines

Country Status (6)

Country Link
US (1) US4341707A (fr)
JP (1) JPS55145665A (fr)
DE (2) DE3016831A1 (fr)
FR (1) FR2455586A1 (fr)
GB (1) GB2049686B (fr)
IT (1) IT1175395B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU144584A (en) * 1983-08-25 1987-06-30 Akad Wissenschaften Ddr Process for making n-(chlorocarbonyloxi)-s-norbornen-2,3-dicarboximide
DE4016596A1 (de) * 1990-05-23 1991-11-28 Hoechst Ag Ein neues kupplungsreagenz fuer die peptidsynthese
US5281698A (en) * 1991-07-23 1994-01-25 Cetus Oncology Corporation Preparation of an activated polymer ester for protein conjugation
AT404250B (de) * 1996-04-04 1998-09-25 Chemie Linz Gmbh Verfahren zur herstellung von carbonsäuresuccinimidylestern
DE19928236C2 (de) * 1999-06-21 2002-05-16 Gottschall Instruction Ges Fue Verfahren zur Herstellung von Kondensationsverbindungen
WO2002076927A2 (fr) * 2001-03-28 2002-10-03 Bayer Aktiengesellschaft Procede pour la production d'amides d'acide carboxylique
JP5598466B2 (ja) * 2009-04-02 2014-10-01 日産化学工業株式会社 ポリアミック酸アルキルエステルを含有するポリイミド前駆体組成物
CN112574038A (zh) * 2021-01-07 2021-03-30 北京微量化学研究所 一种柠檬酸单酯的选择性合成方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670556A1 (de) * 1967-03-13 1971-02-11 Akad Wissenschaften Ddr Verfahren zur Herstellung von gemischten Alkylkohlensaeureestern NN-disubstituierter Hydroxylamine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA574953A (fr) * 1959-04-28 Kuhle Engelbert Fongicides
US3317559A (en) * 1963-08-23 1967-05-02 American Cyanamid Co alpha-amino acid esters of n-hydroxysuccinimide and preparation and use in peptide synthesis
US3651012A (en) * 1969-04-25 1972-03-21 Gen Electric Novel bis-imide compositions and polymers therefrom
DE2631656C2 (de) * 1976-07-14 1983-02-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung eines Hydroxysuccinimidoester-Derivats zur Bindung von biologisch aktiven Proteinen aneinander und/oder an flüssige oder feste Trägerstoffe
US4030173A (en) * 1976-07-26 1977-06-21 Corning Glass Works Pin handling and insertion mechanism

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670556A1 (de) * 1967-03-13 1971-02-11 Akad Wissenschaften Ddr Verfahren zur Herstellung von gemischten Alkylkohlensaeureestern NN-disubstituierter Hydroxylamine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/69 *

Also Published As

Publication number Publication date
DE3016831C2 (fr) 1989-12-07
FR2455586B1 (fr) 1983-03-11
GB2049686B (en) 1983-06-15
GB2049686A (en) 1980-12-31
IT1175395B (it) 1987-07-01
JPS55145665A (en) 1980-11-13
IT8009417A0 (it) 1980-04-30
JPH0112751B2 (fr) 1989-03-02
DE3051115C2 (fr) 1989-12-28
DE3016831A1 (de) 1980-12-04
US4341707A (en) 1982-07-27

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